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Protein

Peptidyl-prolyl cis-trans isomerase cyp3

Gene

cyp3

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).By similarity

Catalytic activityi

Peptidylproline (omega=180) = peptidylproline (omega=0).

GO - Molecular functioni

  • peptidyl-prolyl cis-trans isomerase activity Source: PomBase

GO - Biological processi

Keywordsi

Molecular functionIsomerase, Rotamase

Names & Taxonomyi

Protein namesi
Recommended name:
Peptidyl-prolyl cis-trans isomerase cyp3 (EC:5.2.1.8)
Short name:
PPIase cyp3
Alternative name(s):
Rotamase cyp3
Gene namesi
Name:cyp3
ORF Names:SPBC1709.04c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC1709.04c
PomBaseiSPBC1709.04c cyp3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002329591 – 173Peptidyl-prolyl cis-trans isomerase cyp3Add BLAST173

Proteomic databases

MaxQBiO74729
PaxDbiO74729
PRIDEiO74729

Interactioni

Protein-protein interaction databases

BioGridi276731, 19 interactors
STRINGi4896.SPBC1709.04c.1

Structurei

3D structure databases

ProteinModelPortaliO74729
SMRiO74729
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 172PPIase cyclophilin-typePROSITE-ProRule annotationAdd BLAST165

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000065981
InParanoidiO74729
KOiK09567
OMAiDRPLTNC
OrthoDBiEOG092C5DG5
PhylomeDBiO74729

Family and domain databases

Gene3Di2.40.100.10, 1 hit
InterProiView protein in InterPro
IPR029000 Cyclophilin-like_dom_sf
IPR024936 Cyclophilin-type_PPIase
IPR020892 Cyclophilin-type_PPIase_CS
IPR002130 Cyclophilin-type_PPIase_dom
PANTHERiPTHR11071 PTHR11071, 1 hit
PfamiView protein in Pfam
PF00160 Pro_isomerase, 1 hit
PIRSFiPIRSF001467 Peptidylpro_ismrse, 1 hit
PRINTSiPR00153 CSAPPISMRASE
SUPFAMiSSF50891 SSF50891, 1 hit
PROSITEiView protein in PROSITE
PS00170 CSA_PPIASE_1, 1 hit
PS50072 CSA_PPIASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

O74729-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTEPVVFMD IAIDGRLLGR IKIRLFSSIV PKTAENFRQF CTGETLGVNQ
60 70 80 90 100
KPIGYKNSTF HRIIQGFMIQ GGDFVSGDGT GSATIFNSRT FPDENFTLKH
110 120 130 140 150
DRPGLLSMAN AGKDSNGCQF FITTVPCDFL DGKHVVFGEV IEGYDIVKEI
160 170
ESTPVGANSR PKSNVAIVEC GEM
Length:173
Mass (Da):18,906
Last modified:November 1, 1998 - v1
Checksum:i116DA3AF5FED08B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329671 Genomic DNA Translation: CAA21243.1
PIRiT39632
RefSeqiNP_595437.1, NM_001021345.2

Genome annotation databases

EnsemblFungiiSPBC1709.04c.1; SPBC1709.04c.1:pep; SPBC1709.04c
GeneIDi2540198
KEGGispo:SPBC1709.04c

Similar proteinsi

Entry informationi

Entry nameiPPIH_SCHPO
AccessioniPrimary (citable) accession number: O74729
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 18, 2006
Last sequence update: November 1, 1998
Last modified: March 28, 2018
This is version 114 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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