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UniProtKB - O74556 (YCZ2_SCHPO)
Protein
Putative mannan endo-1,6-alpha-mannosidase C970.02
Gene
SPCC970.02
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Catalytic activityi
- Random hydrolysis of (1->6)-alpha-D-mannosidic linkages in unbranched (1->6)-mannans. EC:3.2.1.101
GO - Molecular functioni
- mannan endo-1,6-alpha-mannosidase activity Source: PomBase
GO - Biological processi
- cellular oligosaccharide catabolic process Source: PomBase
- fungal-type cell wall biogenesis Source: PomBase
Keywordsi
Molecular function | Glycosidase, Hydrolase |
Protein family/group databases
CAZyi | GH76, Glycoside Hydrolase Family 76 |
Names & Taxonomyi
Protein namesi | Recommended name: Putative mannan endo-1,6-alpha-mannosidase C970.02 (EC:3.2.1.101)Alternative name(s): Endo-alpha-1->6-D-mannanase C970.02 |
Gene namesi | ORF Names:SPCC970.02 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPCC970.02 |
VEuPathDBi | FungiDB:SPCC970.02 |
Subcellular locationi
Endoplasmic reticulum
- endoplasmic reticulum Source: PomBase
Plasma Membrane
- anchored component of external side of plasma membrane Source: PomBase
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_0000012131 | 20 – 442 | Putative mannan endo-1,6-alpha-mannosidase C970.02Add BLAST | 423 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 25 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 82 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 107 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 131 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 201 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 236 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 261 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 264 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 277 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 361 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | O74556 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 275485, 3 interactors |
STRINGi | 4896.SPCC970.02.1 |
Family & Domainsi
Sequence similaritiesi
Belongs to the glycosyl hydrolase 76 family.Curated
Keywords - Domaini
SignalPhylogenomic databases
eggNOGi | ENOG502QSWP, Eukaryota |
HOGENOMi | CLU_025694_1_2_1 |
InParanoidi | O74556 |
OMAi | DIDKTQW |
PhylomeDBi | O74556 |
Family and domain databases
InterProi | View protein in InterPro IPR008928, 6-hairpin_glycosidase_sf IPR005198, Glyco_hydro_76 IPR014480, Mannan-1_6-alpha_mannosidase |
PANTHERi | PTHR12145, PTHR12145, 1 hit |
Pfami | View protein in Pfam PF03663, Glyco_hydro_76, 1 hit |
PIRSFi | PIRSF016302, Man_a_manosd, 1 hit |
SUPFAMi | SSF48208, SSF48208, 1 hit |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
O74556-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSLTIFISLA TILFSFAEAI SVDLNDTSSV DLATSLVADG LLNYYAGQHK
60 70 80 90 100
GGTIGMFLPP AYWWEAGAAW NGLLNRYIAT GNSTYNELVK TSMLYQSGED
110 120 130 140 150
SDYMPSNYTT SEGNDDQAFW GLTVISAAEA NFSNPAADEP QWLELAQAVF
160 170 180 190 200
NQQVTRWDTD HCNGGLRWQI TEFNSGYNYK NTVSNGAFFQ LAARLARFTD
210 220 230 240 250
NDTYAEWANV AYDWSQRIGF IQEDYTVFDG SSIKDNCSSI EITQWTYNIG
260 270 280 290 300
LYMAGAAYMY NYTNSTVWKT RVEGFANKTA KTFFFKDIMF EPVCEIALSC
310 320 330 340 350
NYDQTSFKGF LTRFMVYTAQ MAPFTAPLLE PLLISTAKAA AGACCGGYDG
360 370 380 390 400
VTCGVQWWWN NDTWDGLYGL GEQMSALEAI QAPLLLKSLQ VFKASNGGSS
410 420 430 440
TGDPNAGLYT APVSFANKNF ENLRKHWMLL GFFLLVPTLV LY
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329672 Genomic DNA Translation: CAA20695.1 |
PIRi | T41678 |
RefSeqi | NP_587853.1, NM_001022846.2 |
Genome annotation databases
EnsemblFungii | SPCC970.02.1; SPCC970.02.1:pep; SPCC970.02 |
GeneIDi | 2538908 |
KEGGi | spo:SPCC970.02 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329672 Genomic DNA Translation: CAA20695.1 |
PIRi | T41678 |
RefSeqi | NP_587853.1, NM_001022846.2 |
3D structure databases
SMRi | O74556 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 275485, 3 interactors |
STRINGi | 4896.SPCC970.02.1 |
Protein family/group databases
CAZyi | GH76, Glycoside Hydrolase Family 76 |
Proteomic databases
PaxDbi | O74556 |
Genome annotation databases
EnsemblFungii | SPCC970.02.1; SPCC970.02.1:pep; SPCC970.02 |
GeneIDi | 2538908 |
KEGGi | spo:SPCC970.02 |
Organism-specific databases
PomBasei | SPCC970.02 |
VEuPathDBi | FungiDB:SPCC970.02 |
Phylogenomic databases
eggNOGi | ENOG502QSWP, Eukaryota |
HOGENOMi | CLU_025694_1_2_1 |
InParanoidi | O74556 |
OMAi | DIDKTQW |
PhylomeDBi | O74556 |
Miscellaneous databases
PROi | PR:O74556 |
Family and domain databases
InterProi | View protein in InterPro IPR008928, 6-hairpin_glycosidase_sf IPR005198, Glyco_hydro_76 IPR014480, Mannan-1_6-alpha_mannosidase |
PANTHERi | PTHR12145, PTHR12145, 1 hit |
Pfami | View protein in Pfam PF03663, Glyco_hydro_76, 1 hit |
PIRSFi | PIRSF016302, Man_a_manosd, 1 hit |
SUPFAMi | SSF48208, SSF48208, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | YCZ2_SCHPO | |
Accessioni | O74556Primary (citable) accession number: O74556 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 31, 2004 |
Last sequence update: | November 1, 1998 | |
Last modified: | September 29, 2021 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - Glycosyl hydrolases
Classification of glycosyl hydrolase families and list of entries - SIMILARITY comments
Index of protein domains and families