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Entry version 155 (29 Sep 2021)
Sequence version 1 (01 Nov 1998)
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Protein

Probable cation-transporting ATPase C1672.11c

Gene

SPCC1672.11c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei6194-aspartylphosphate intermediateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi1015MagnesiumBy similarity1
Metal bindingi1019MagnesiumBy similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-SPO-936837, Ion transport by P-type ATPases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Probable cation-transporting ATPase C1672.11c (EC:7.2.2.-)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:SPCC1672.11c
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri284812 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002485 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome III

Organism-specific databases

Schizosaccharomyces pombe database

More...
PomBasei
SPCC1672.11c

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
FungiDB:SPCC1672.11c

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 139CytoplasmicSequence analysisAdd BLAST139
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei140 – 161HelicalSequence analysisAdd BLAST22
Topological domaini162 – 167ExtracellularSequence analysis6
Transmembranei168 – 190HelicalSequence analysisAdd BLAST23
Topological domaini191 – 324CytoplasmicSequence analysisAdd BLAST134
Transmembranei325 – 347HelicalSequence analysisAdd BLAST23
Topological domaini348 – 350ExtracellularSequence analysis3
Transmembranei351 – 369HelicalSequence analysisAdd BLAST19
Topological domaini370 – 531CytoplasmicSequence analysisAdd BLAST162
Transmembranei532 – 551HelicalSequence analysisAdd BLAST20
Topological domaini552 – 564ExtracellularSequence analysisAdd BLAST13
Transmembranei565 – 586HelicalSequence analysisAdd BLAST22
Topological domaini587 – 1072CytoplasmicSequence analysisAdd BLAST486
Transmembranei1073 – 1091HelicalSequence analysisAdd BLAST19
Topological domaini1092 – 1099ExtracellularSequence analysis8
Transmembranei1100 – 1117HelicalSequence analysisAdd BLAST18
Topological domaini1118 – 1135CytoplasmicSequence analysisAdd BLAST18
Transmembranei1136 – 1159HelicalSequence analysisAdd BLAST24
Topological domaini1160 – 1180ExtracellularSequence analysisAdd BLAST21
Transmembranei1181 – 1203HelicalSequence analysisAdd BLAST23
Topological domaini1204 – 1216CytoplasmicSequence analysisAdd BLAST13
Transmembranei1217 – 1236HelicalSequence analysisAdd BLAST20
Topological domaini1237 – 1253ExtracellularSequence analysisAdd BLAST17
Transmembranei1254 – 1274HelicalSequence analysisAdd BLAST21
Topological domaini1275 – 1315CytoplasmicSequence analysisAdd BLAST41

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000463521 – 1315Probable cation-transporting ATPase C1672.11cAdd BLAST1315

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O74431

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O74431

PRoteomics IDEntifications database

More...
PRIDEi
O74431

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O74431

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
275332, 3 interactors

STRING: functional protein association networks

More...
STRINGi
4896.SPCC1672.11c.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0208, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001828_3_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O74431

Identification of Orthologs from Complete Genome Data

More...
OMAi
GFKFYED

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O74431

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR036412, HAD-like_sf
IPR006544, P-type_TPase_V
IPR001757, P_typ_ATPase
IPR044492, P_typ_ATPase_HD_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12409, P5-ATPase, 1 hit

Structure-Function Linkage Database

More...
SFLDi
SFLDF00027, p-type_atpase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81660, SSF81660, 1 hit
SSF81665, SSF81665, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01494, ATPase_P-type, 3 hits
TIGR01657, P-ATPase-V, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O74431-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASPKMIRSK RSTSSIASKN SLNSYLASSL MSHDSIFDGP GLGTSIPSSV
60 70 80 90 100
SSFHHQTLRP SSDASVSQFS MDYLQSEYNL NRYNDGESIA ASRDYQSLLR
110 120 130 140 150
DNGSGVYSDE EEITEMMLEE LNIHPVLRRE SVGEAAGLSE DGCCQILYLV
160 170 180 190 200
EEDLEVGIAG YKTNKSRYRL YQAICLLTLG LAYLIFRWLP KYFIRFVGTR
210 220 230 240 250
EPLATADWLT IETQWGELSK LDIQIQPYEN SLSSIFGASI RVAAPEGTEN
260 270 280 290 300
DPFIENFRYV NYRYMKLIFH PLLDRFLIQQ DWKDPRWIRD TSVVKEGLER
310 320 330 340 350
DAINDRLCIF GENLIDLELK SVSQLLIDEV LHPFYIFQVF SIILWSMDSY
360 370 380 390 400
YYYAICILII SVVSILGSLI ETRKTLRRMR EMSRFTCPVR VYRDGFWTSI
410 420 430 440 450
SSTDLVIGDV FEISDPELTI FPADALLLSG DCIVNESMLT GESIPVSKIP
460 470 480 490 500
ATDQSMKELF SFSKNIPASL CKHFLFSGTK IIQVRKPFVN EKEEGASLAM
510 520 530 540 550
VVRTGFNTTK GALVRSMIFP KPTNFSFYRD SFRFITAMFI IALIGFVFSS
560 570 580 590 600
INLLTLGVPI ATIIIRALDL ITIVVPPALP ATLTIGTTFA ISRLRKQGIF
610 620 630 640 650
CISPQRVNVS GKLDLISFDK TGTLTEDGLD IMGVSVIEGS ELGDLRSNSG
660 670 680 690 700
NLCSKDLLSN DSPSNLLYTM ATCHMLRYVD GELVGDPLDI KMFKFTHWSY
710 720 730 740 750
SEENFLNKKM SSEQAEDAAY VRTQQLIPPT VSPPWNSPSN NYTESDLELG
760 770 780 790 800
IVRTFEFVSQ LRRMAVIVKH GKFKKMDAYV KGAPEIMPSI CKPESFPANY
810 820 830 840 850
QEVLDYYTHN GFRVIACASK QLENCTWAKA QRMKREQVEC DLDFCGFIVF
860 870 880 890 900
ENKLKSTTAT VIRELNDARI RTVMCTGDNV LTSICVGKRC GMLPEDGYVF
910 920 930 940 950
LPRFDEESES ADEASRQLVW QAIENNEIFL DPHTLRPNVD FADHEPVSIE
960 970 980 990 1000
LARLKDFHIA LTGDVFRWLV DYAPLNVFHH ILLKAQIFAR MSPSEKNELV
1010 1020 1030 1040 1050
SCFQNLNYCV GFCGDGANDC GALKAADVGI SLSEAEASVA APFTSKWFEI
1060 1070 1080 1090 1100
TCVLDVIKDG RAALVTSFSC FQYMALYSAI QFITVSILYT TNSNLGDFQF
1110 1120 1130 1140 1150
LFIDLVIILP IAVFMGRSRP YHRLAHKRPT ANLVSKRILS PLIGQIVLIC
1160 1170 1180 1190 1200
IIQYITLRIV RREPWYIPPP ANSSDTNITN SDVTALFLIS CFQYIFIGVV
1210 1220 1230 1240 1250
LSIGPPYREK VWRNYSFTAV VVVLLILTVK LIRLQNHKNF FMKLFQLTPT
1260 1270 1280 1290 1300
SKSFQNFLIF AGVIYYLLAA SGQNYIFISM TNFISHLNNR LLNRRTKVSK
1310
KLYKRLFADL QNEQV
Length:1,315
Mass (Da):148,787
Last modified:November 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i081A550E59F2B0B5
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20449.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T41055

NCBI Reference Sequences

More...
RefSeqi
NP_587882.1, NM_001022874.2

Genome annotation databases

Ensembl fungal genome annotation project

More...
EnsemblFungii
SPCC1672.11c.1; SPCC1672.11c.1:pep; SPCC1672.11c

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
2538749

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
spo:SPCC1672.11c

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA20449.1
PIRiT41055
RefSeqiNP_587882.1, NM_001022874.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi275332, 3 interactors
STRINGi4896.SPCC1672.11c.1

PTM databases

iPTMnetiO74431

Proteomic databases

MaxQBiO74431
PaxDbiO74431
PRIDEiO74431

Genome annotation databases

EnsemblFungiiSPCC1672.11c.1; SPCC1672.11c.1:pep; SPCC1672.11c
GeneIDi2538749
KEGGispo:SPCC1672.11c

Organism-specific databases

PomBaseiSPCC1672.11c
VEuPathDBiFungiDB:SPCC1672.11c

Phylogenomic databases

eggNOGiKOG0208, Eukaryota
HOGENOMiCLU_001828_3_1_1
InParanoidiO74431
OMAiGFKFYED
PhylomeDBiO74431

Enzyme and pathway databases

ReactomeiR-SPO-936837, Ion transport by P-type ATPases

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O74431

Family and domain databases

InterProiView protein in InterPro
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR036412, HAD-like_sf
IPR006544, P-type_TPase_V
IPR001757, P_typ_ATPase
IPR044492, P_typ_ATPase_HD_dom
PfamiView protein in Pfam
PF12409, P5-ATPase, 1 hit
SFLDiSFLDF00027, p-type_atpase, 1 hit
SUPFAMiSSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81660, SSF81660, 1 hit
SSF81665, SSF81665, 1 hit
TIGRFAMsiTIGR01494, ATPase_P-type, 3 hits
TIGR01657, P-ATPase-V, 1 hit
PROSITEiView protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiATC9_SCHPO
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O74431
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 1, 1998
Last modified: September 29, 2021
This is version 155 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families
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