UniProtKB - O74202 (O74202_EMEND)
Protein
Plasma membrane ATPase
Gene
pmaA
Organism
Emericella nidulans (Aspergillus nidulans)
Status
Functioni
The plasma membrane ATPase of plants and fungi is a hydrogen ion pump. The proton gradient it generates drives the active transport of nutrients by H+-symport. The resulting external acidification and/or internal alkinization may mediate growth responses.ARBA annotation
Catalytic activityi
- EC:7.1.2.1UniRule annotationARBA annotation
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- proton-exporting ATPase activity, phosphorylative mechanism Source: UniProtKB-UniRule
GO - Biological processi
- proton export across plasma membrane Source: UniProtKB-UniRule
Keywordsi
Molecular function | TranslocaseUniRule annotation |
Biological process | Hydrogen ion transportUniRule annotation, Ion transport, Transport |
Ligand | ATP-bindingUniRule annotationARBA annotation, MagnesiumUniRule annotation, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:pmaAImported |
Organismi | Emericella nidulans (Aspergillus nidulans)Imported |
Taxonomic identifieri | 162425 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Aspergillaceae › Aspergillus › Aspergillus subgen. Nidulantes |
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-UniRule
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 119 – 142 | HelicalUniRule annotationAdd BLAST | 24 | |
Transmembranei | 148 – 167 | HelicalUniRule annotationAdd BLAST | 20 | |
Transmembranei | 338 – 359 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 379 – 406 | HelicalUniRule annotationAdd BLAST | 28 | |
Transmembranei | 737 – 758 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 764 – 788 | HelicalUniRule annotationAdd BLAST | 25 | |
Transmembranei | 800 – 818 | HelicalUniRule annotationAdd BLAST | 19 | |
Transmembranei | 838 – 854 | HelicalUniRule annotationAdd BLAST | 17 | |
Transmembranei | 866 – 887 | HelicalUniRule annotationAdd BLAST | 22 | |
Transmembranei | 915 – 939 | HelicalUniRule annotationAdd BLAST | 25 |
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 78 – 147 | Cation_ATPase_NInterPro annotationAdd BLAST | 70 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 27 | DisorderedSequence analysisAdd BLAST | 27 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 26 | PolyampholyteSequence analysisAdd BLAST | 26 |
Sequence similaritiesi
Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. [View classification]UniRule annotationARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixUniRule annotationARBA annotationFamily and domain databases
CDDi | cd02076, P-type_ATPase_H, 1 hit |
Gene3Di | 3.40.1110.10, 1 hit |
InterProi | View protein in InterPro IPR004014, ATPase_P-typ_cation-transptr_N IPR023299, ATPase_P-typ_cyto_dom_N IPR018303, ATPase_P-typ_P_site IPR023298, ATPase_P-typ_TM_dom_sf IPR008250, ATPase_P-typ_transduc_dom_A_sf IPR036412, HAD-like_sf IPR006534, P-type_ATPase_IIIA IPR001757, P_typ_ATPase |
Pfami | View protein in Pfam PF00690, Cation_ATPase_N, 1 hit |
PRINTSi | PR00120, HATPASE |
SMARTi | View protein in SMART SM00831, Cation_ATPase_N, 1 hit |
SUPFAMi | SSF56784, SSF56784, 1 hit SSF81653, SSF81653, 2 hits SSF81665, SSF81665, 1 hit |
TIGRFAMsi | TIGR01647, ATPase-IIIA_H, 1 hit TIGR01494, ATPase_P-type, 2 hits |
PROSITEi | View protein in PROSITE PS00154, ATPASE_E1_E2, 1 hit |
i Sequence
Sequence statusi: Complete.
O74202-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAERKISYAA DVENGDHSRP TDVNDDAGLD EYGPLNRYIS TARDNRCGST
60 70 80 90 100
SSAGALSMKQ KKKPWYKFWA KAGGENGEEG FVAPEDWLET DLNGLPSSQI
110 120 130 140 150
EPRRKRGGWN ELTTEKTNFF VQFIGYFRGP ILYVMELAVL LAAGLRDWID
160 170 180 190 200
LGVIIGILML NAVVGWYQEK QAGNVVASLK GDIAMKAVVK RDGQEQEILA
210 220 230 240 250
RELVTGDIVV IEEGTIVPAD VRLICDYDKP ETYETYKEYL ATANDDTLKE
260 270 280 290 300
NDDDDDDHGI EARLGVSLVA VDQSAITGES LAVDKYMADT CYYTTGCKRG
310 320 330 340 350
KAYAIVTATA KHSFVGKTAA LVQGAQDQGH FKAVMDNIGT SLLVLVMFWI
360 370 380 390 400
LAAWIGGFYR HLKIATPEHS DNTLLHWTLI LLIIGVPVGL PVVTTTTLAV
410 420 430 440 450
GAAYLAEQKA IVQKLTAIES LAGVDILCSD KTGTLTANQL SIREPYVNEG
460 470 480 490 500
VDVNWMMAVA AIASNHNVKN LDPIDKVTIL TLRRYPKARE ILARNWVTEK
510 520 530 540 550
YTPFDPVSKR ITTICTCDGV RYTCAKGAPK AILAMSECSP EEAQKFREKA
560 570 580 590 600
SEFARRGFRS LGVAVQKEGE PWQLLGMYPM FDPPREDTAH TIAEAQHLGL
610 620 630 640 650
SVKMLTGDAL AIAKETCKML ALSTKVYDSE RLIHGGLAGS AQHDLVEKAD
660 670 680 690 700
GFAEVFPEHK YQVVEMLQQC GHLTAMTGDG VNDAPSLKKA DCGIAVEGST
710 720 730 740 750
EAAQAAADIV FLAPGLSTIV DAIKLARQIF QRMKAYIQYR IALCIHLELY
760 770 780 790 800
LVTSMIIINE TIKADLIVFI ALFADLATIA VAYDNAHFEA RPVEWQLPKI
810 820 830 840 850
WVISVVLGVL LAAGTWIMRA SLFLENGGII QNFGSPQPML FLEVSLTENW
860 870 880 890 900
LIFVTRGGKT WPSWQLVGAI FVVDVLATLF CVFGWLAGDY VETSPPSQAT
910 920 930 940 950
FSTNNDTDIV TVVVIWAYSI GVTIIIAVVY YLLTIIPALD NLGRKNRSVV
960 970 980 990
DTKVENLLNH LSKLAIEHEV DANGKSRYTL GARAEPEDDE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF036763 Genomic DNA Translation: AAC27991.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF036763 Genomic DNA Translation: AAC27991.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family and domain databases
CDDi | cd02076, P-type_ATPase_H, 1 hit |
Gene3Di | 3.40.1110.10, 1 hit |
InterProi | View protein in InterPro IPR004014, ATPase_P-typ_cation-transptr_N IPR023299, ATPase_P-typ_cyto_dom_N IPR018303, ATPase_P-typ_P_site IPR023298, ATPase_P-typ_TM_dom_sf IPR008250, ATPase_P-typ_transduc_dom_A_sf IPR036412, HAD-like_sf IPR006534, P-type_ATPase_IIIA IPR001757, P_typ_ATPase |
Pfami | View protein in Pfam PF00690, Cation_ATPase_N, 1 hit |
PRINTSi | PR00120, HATPASE |
SMARTi | View protein in SMART SM00831, Cation_ATPase_N, 1 hit |
SUPFAMi | SSF56784, SSF56784, 1 hit SSF81653, SSF81653, 2 hits SSF81665, SSF81665, 1 hit |
TIGRFAMsi | TIGR01647, ATPase-IIIA_H, 1 hit TIGR01494, ATPase_P-type, 2 hits |
PROSITEi | View protein in PROSITE PS00154, ATPASE_E1_E2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | O74202_EMEND | |
Accessioni | O74202Primary (citable) accession number: O74202 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1998 |
Last sequence update: | November 1, 1998 | |
Last modified: | October 7, 2020 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |