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Protein
Submitted name:

Homeobox protein Six6

Gene

six3b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi168 – 227HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

  • brain development Source: ZFIN
  • embryonic camera-type eye morphogenesis Source: ZFIN
  • eye development Source: ZFIN
  • optic nerve development Source: ZFIN
  • optic nerve morphogenesis Source: ZFIN
  • sensory epithelium regeneration Source: ZFIN

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationImported

Names & Taxonomyi

Protein namesi
Submitted name:
Homeobox protein Six6Imported
Submitted name:
SIX homeobox 3bImported
Submitted name:
Sine oculis homeobox homolog 3bImported
Submitted name:
Six3Imported
Gene namesi
Name:six3bImported
Synonyms:six3Imported, six6Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
Proteomesi
  • UP000000437 Componenti: Chromosome 12

Organism-specific databases

ZFINiZDB-GENE-990415-128 six3b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000054879

Interactioni

Protein-protein interaction databases

STRINGi7955.ENSDARP00000071625

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini166 – 226HomeoboxInterPro annotationAdd BLAST61

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationImported

Phylogenomic databases

eggNOGiKOG0775 Eukaryota
ENOG410XRPB LUCA
GeneTreeiENSGT00540000070251
HOGENOMiHOG000261680
HOVERGENiHBG003609
OrthoDBiEOG091G083I
TreeFamiTF315545

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR001356 Homeobox_dom
IPR031701 SIX1_SD
IPR032949 SIX3
PANTHERiPTHR10390:SF31 PTHR10390:SF31, 1 hit
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PF16878 SIX1_SD, 1 hit
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

O73709-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVFRSPLELY PSHLFLPNFA DRPLLLAGSI PRARSPEDLP MFQLPTLNFS
60 70 80 90 100
AEQVASVCET LEETGDIERL GRFLWSLPVA PGACDAINKH ESIQRARAVV
110 120 130 140 150
AYHTGSFREL YHILETHKFT KDSHGKLQAM WLEAHYQEAE KLRGRPLGPV
160 170 180 190 200
DKYRVRKKFP LPRTIWDGEQ KTHCFKERTR GLLREWYLQD PYPNPSKKRE
210 220 230 240 250
LAQATGLTPT QVGNWFKNRR QRDRAAAAKN RLQHHGLGQS SLRSMSESGC
260 270 280 290
TPHSSAESPC AAASPTTSVS SMNERGDGGT ILSVTDSDSD FDV
Length:293
Mass (Da):33,012
Last modified:August 1, 1998 - v1
Checksum:i56EC18007B2C676D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR932018 Genomic DNA No translation available.
AF030281 mRNA Translation: AAC27449.1
BC059425 mRNA Translation: AAH59425.1
AB004881 mRNA Translation: BAA31752.1
RefSeqiNP_571438.1, NM_131363.1
UniGeneiDr.75402

Genome annotation databases

EnsembliENSDART00000077157; ENSDARP00000071625; ENSDARG00000054879
GeneIDi30636
KEGGidre:30636

Similar proteinsi

Entry informationi

Entry nameiO73709_DANRE
AccessioniPrimary (citable) accession number: O73709
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 137 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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