UniProtKB - O72159 (O72159_9VIRU)
Protein
N-terminal protein
Gene
N/A
Organism
Southern bean mosaic virus
Status
Functioni
covalently attached to the 5' extremity of the genomic and subgenomic RNAs. It may serve as a primer for the replicase.ARBA annotation
responsible for cleavages of polyprotein P2A and replicase polyprotein P2AB.ARBA annotation
Catalytic activityi
- EC:2.7.7.48ARBA annotation
GO - Molecular functioni
- nucleotide binding Source: UniProtKB-KW
- RNA binding Source: InterPro
- RNA-directed 5'-3' RNA polymerase activity Source: UniProtKB-KW
- serine-type endopeptidase activity Source: InterPro
GO - Biological processi
- transcription, DNA-templated Source: InterPro
- viral process Source: InterPro
Keywordsi
Molecular function | Hydrolase, Nucleotidyltransferase, ProteaseImportedARBA annotation, RNA-directed RNA polymeraseARBA annotation, Transferase |
Ligand | Nucleotide-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: N-terminal proteinARBA annotation (EC:2.7.7.48ARBA annotation)Alternative name(s): Serine proteaseARBA annotation VPgARBA annotation |
Organismi | Southern bean mosaic virusImported |
Taxonomic identifieri | 12139 [NCBI] |
Taxonomic lineagei | Viruses › Riboviria › Orthornavirae › Pisuviricota › Pisoniviricetes › Sobelivirales › Solemoviridae › Sobemovirus |
Subcellular locationi
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 6 – 24 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 36 – 61 | HelicalSequence analysisAdd BLAST | 26 |
GO - Cellular componenti
- host cell membrane Source: UniProtKB-SubCell
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 135 – 335 | Peptidase S39InterPro annotationAdd BLAST | 201 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 515 – 562 | DisorderedSequence analysisAdd BLAST | 48 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 515 – 540 | PolarSequence analysisAdd BLAST | 26 |
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisFamily and domain databases
Gene3Di | 2.40.10.10, 2 hits |
InterProi | View protein in InterPro IPR043502, DNA/RNA_pol_sf IPR009003, Peptidase_S1_PA IPR043504, Peptidase_S1_PA_chymotrypsin IPR000382, Peptidase_S39B_luteovirus IPR001795, RNA-dir_pol_luteovirus |
Pfami | View protein in Pfam PF02122, Peptidase_S39, 2 hits PF02123, RdRP_4, 1 hit |
PRINTSi | PR00914, LVIRUSRNAPOL |
SUPFAMi | SSF50494, SSF50494, 1 hit SSF56672, SSF56672, 1 hit |
PROSITEi | View protein in PROSITE PS51868, PEPTIDASE_S39, 1 hit |
i Sequence
Sequence statusi: Complete.
O72159-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MYHPGRSPSF LITLANVICA AILFDIHTGG YQPGSLIPIV AWMTPFVTLL
60 70 80 90 100
WLSASFATYL YKYVRTRLLP EEKVARVYYT AQSAPYFDPA LGVMMQFAPS
110 120 130 140 150
HGGASIEVQV NPSWISLLGG SLKINGDDAS NESAVLGSFY SSVKPGDEPA
160 170 180 190 200
SLVAIKSGPQ TIGFGCRTKI DGDDCLFTAN HVWNNSMRPT ALAKRGKQVA
210 220 230 240 250
IEDWETPLSC DHKMLDFVVV RVPKHVWSKL GVKATQLVCP SDKDAVTCYG
260 270 280 290 300
GSSSDNLLSG TGVCSKVDFS WKLTHSCPTA AGWSGTPIYS SRGVVGMHVG
310 320 330 340 350
FEDIGKLNRG VNAFYVSNYL LRSQETLPPE LSVIEIPFED VETRSYEFIE
360 370 380 390 400
VEIKGRGKAK LGKREFAWIP ESGKYWADDD DDSLPPPPKV VDGKMVWSSA
410 420 430 440 450
QETVAEPLNY QRAAGSRPLP PFLNLQATTS KKEKQPLQEE CPLDLLGSRL
460 470 480 490 500
ASLESCVEKI LQMKSLELLG SSQNCQTSPG PSEAPKQSFT PCYSKQESLI
510 520 530 540 550
PLESQGILKE LVKTSLSATP PPNPVTVSVE KPGPSTQSTK KSARRRNRRK
560 570 580 590 600
STRKPVQGVP LSRLASTNKD LLKRHLELVA LCVTERLFLL SEAEDLLDES
610 620 630 640 650
PVDLVRRGLC DPVRLFVKQE PHASRKVREG RFRLISSVSL VDQLVERMLF
660 670 680 690 700
GPQNQLEIAE WEHIPSKPGM GLSLRQQAKS LFDDLRVKHS RCPAAEADIS
710 720 730 740 750
GFDWSVQDWE LWADVEMRIV LGGFGHKLAK AAQNRFSCFM NSVFQLSDGT
760 770 780 790 800
LIEQQLPGIM KSGSYCTSST NSRIRCLMAE LIGSPWCIAM GDDSVEGWVD
810 820 830 840 850
GAKDKYMRLG HTCKDYKPCA TTISGRLYEV EFCSHVIRED RCWLASWPKT
860 870 880 890 900
LFKYLSEGKW FFEDLERDVS SSPHWPRIRH YVVGNTPSPH KTNLQNQSPR
910 920 930 940 950
YGEEVDKTTV NQGYSEHSGS PGHSIEEAQE PERAPFCCEA ASVYPGWGVH
960
GPYCSGDYGS LT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF055888 Genomic RNA Translation: AAC15987.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF055888 Genomic RNA Translation: AAC15987.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Family and domain databases
Gene3Di | 2.40.10.10, 2 hits |
InterProi | View protein in InterPro IPR043502, DNA/RNA_pol_sf IPR009003, Peptidase_S1_PA IPR043504, Peptidase_S1_PA_chymotrypsin IPR000382, Peptidase_S39B_luteovirus IPR001795, RNA-dir_pol_luteovirus |
Pfami | View protein in Pfam PF02122, Peptidase_S39, 2 hits PF02123, RdRP_4, 1 hit |
PRINTSi | PR00914, LVIRUSRNAPOL |
SUPFAMi | SSF50494, SSF50494, 1 hit SSF56672, SSF56672, 1 hit |
PROSITEi | View protein in PROSITE PS51868, PEPTIDASE_S39, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | O72159_9VIRU | |
Accessioni | O72159Primary (citable) accession number: O72159 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 1, 1998 |
Last sequence update: | August 1, 1998 | |
Last modified: | December 2, 2020 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |