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Entry version 112 (02 Jun 2021)
Sequence version 1 (01 Aug 1998)
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Protein

Genome polyprotein

Gene
N/A
Organism
Infectious flacherie virus (isolate Silkworm) (IFV) (Bombyx mori infectious flacherie virus)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionHelicaseARBA annotation, Hydrolase, Nucleotidyltransferase, Protease, RNA-directed RNA polymeraseARBA annotation, Thiol proteaseARBA annotation, Transferase
Biological processViral RNA replicationARBA annotation
LigandATP-binding, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Genome polyproteinARBA annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiInfectious flacherie virus (isolate Silkworm) (IFV) (Bombyx mori infectious flacherie virus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri649896 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiVirusesRiboviriaOrthornaviraePisuviricotaPisoniviricetesPicornaviralesIflaviridaeIflavirus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section only exists in viral entries and indicates the host(s) either as a specific organism or taxonomic group of organisms that are susceptible to be infected by a virus.<p><a href='/help/virus_host' target='_top'>More...</a></p>Virus hostiBombyx mori (Silk moth) [TaxID: 7091]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000681 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Genome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1361 – 1533SF3 helicaseInterPro annotationAdd BLAST173
Domaini2209 – 2433Peptidase C3InterPro annotationAdd BLAST225
Domaini2695 – 2823RdRp catalyticInterPro annotationAdd BLAST129

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00205, rhv_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.20, 3 hits
3.30.70.270, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR014872, Dicistrovirus_capsid-polyPr_C
IPR043502, DNA/RNA_pol_sf
IPR000605, Helicase_SF3_ssDNA/RNA_vir
IPR014759, Helicase_SF3_ssRNA_vir
IPR044067, PCV_3C_PRO
IPR009003, Peptidase_S1_PA
IPR001676, Picornavirus_capsid
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR033703, Rhv-like
IPR001205, RNA-dir_pol_C
IPR007094, RNA-dir_pol_PSvirus
IPR029053, Viral_coat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08762, CRPV_capsid, 1 hit
PF00680, RdRP_1, 1 hit
PF00073, Rhv, 1 hit
PF00910, RNA_helicase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50494, SSF50494, 1 hit
SSF56672, SSF56672, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51874, PCV_3C_PRO, 1 hit
PS50507, RDRP_SSRNA_POS, 1 hit
PS51218, SF3_HELICASE_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O70710-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQDSSCEDPG SSPPNQSVAL PRESILSGVL RKNNVAECDV PKSKSILKNK
60 70 80 90 100
TTMLITMDPD TPFSKYVENA QRLVNSMVQY GYDYTVESHV RFIATRTTVT
110 120 130 140 150
LKNGIFKYVI VCDGLRNVKE VNQFVNVAIL VAMKKYLLYD VKRYTQPQGP
160 170 180 190 200
PETTNTTNPE DIVNQTEISQ QSENTEITQA VDTASAPFLL TTHVLQHQST
210 220 230 240 250
TEPKISLNEL TERYIVIANG VLTSGDTRGQ VKFSLDLPAA IYGNLDSSTS
260 270 280 290 300
TALRPFTLMK TDLEITLKIN SNQAQAGRYV LASYPCRRQA FGVADSVFQQ
310 320 330 340 350
IQREHVEVDV STSADAILQI KYENLRNFMP ILTNEVGETT GESFTTLTLT
360 370 380 390 400
CLSPVNVVAG AVDVVPYQVI ARFVNPFLTG MRYPLPVQGQ GPEFPISTTR
410 420 430 440 450
TREKVIETVR DVNNVLGAIP VFGALYKTVM LAGASAVTSV TRFVAPEPYT
460 470 480 490 500
KVLEDTLVYV GMRNKDKPVD TRPYSVLQPV SQKALCHGLG PIGATKMRLE
510 520 530 540 550
MSVNTPHLPD METVQTSESY SELAQIGGVQ EIFTVSTTTP NGRLLIDLPV
560 570 580 590 600
APFDARYLPN TVISGTGEGA SRVLPPVTYI SQLFQGYTGE LEYEFIPVKT
610 620 630 640 650
AAHNFSILVA FVPFDGEPGN TTFAQALSCH YKIIDFRTNS AGVFTVPFVS
660 670 680 690 700
NSMFRSYTGT ESSFMFARNL NTTTYTSPTI GGGLTVGPFA AWKDPGKVSV
710 720 730 740 750
FMLNPLNPTP IVAPEIEIIV KLRGAKNIQF TIPSQPRFRT AYTTDSYVFA
760 770 780 790 800
PIISGVTNAN HWGTVPQGPV QTMNDDEVPG EPTVPLIGPQ MTHMEMHDDI
810 820 830 840 850
LNVNRRLMHY ARLTTDGLYY VDGSGATVYA PMSGSSACIP IVLSDPVFQN
860 870 880 890 900
FGNNGQGSVN SQEMTPRNIR DATASLFRFG RGSVILSILN HSQNNLVISF
910 920 930 940 950
LPPFQRPMYF SAENGTTTSV FSLGVARTSI GLSAPDSQGY ASVRNVPSVN
960 970 980 990 1000
PVTDIEIPFY SSAVYMDLQA RNGLGAALAI MGNSQSMARG PLYDVVTRTL
1010 1020 1030 1040 1050
GTLKIQTELY PFPATAENLA RLQSTVTIRM GLSDDFKFHH FMGTPPVIAN
1060 1070 1080 1090 1100
YPLVPSIGNV ARTLTRAEIE DELIRAGIES NPGPVVKDVG TEPQGMWDFL
1110 1120 1130 1140 1150
NDLVSAPTEL KRVREQGDYF KEVIGSLKEK IVRSFNISVT QAAALASTML
1160 1170 1180 1190 1200
AAYMNPSPYT VVSAVTNLLV ALNIVDDTFL MKVMLGCNEP QNVKGQGPLD
1210 1220 1230 1240 1250
DDKRESPNWI VPLLVSGFVE YCCSAMQKQD IALDPSNIDE RTVFMKLTEA
1260 1270 1280 1290 1300
LTGVNWFRVS AVMVVTSRLV MAFKWLFEKV QSWLRPSTSY LLLKHNPKFI
1310 1320 1330 1340 1350
ENFMNDYTFI MNELNKNSII GIRQCRDRFW TTLLSAYYLK GIMAKERIRN
1360 1370 1380 1390 1400
PTLLNTVNDI IKKANELTSI LSAPPVRFEP FVVWIFGPRG VGKSTLLQQQ
1410 1420 1430 1440 1450
LIDILEQHKG PGKFEHPNPV YTRNPTSQWW NGYNGQPIVL YDDIGAVSSA
1460 1470 1480 1490 1500
EIDPIVAGEL MAIKSCAIMP LEKPRIEEKE SLMTSVIVGI ASNHPCLKSS
1510 1520 1530 1540 1550
VIRDVGAMDR RRDILARCEF TPEVEKYIKS KKLLNVASAL PEEMTRNNKH
1560 1570 1580 1590 1600
LRYGVFKDPT KVRPNTQDVR VETSTEPDMW LTYDEFMEYS IDVFTRYYTK
1610 1620 1630 1640 1650
ELEKMTKRYK DMLRLCPTYA KGLTDEASVR MAIMQMILKV EESKSTTTMD
1660 1670 1680 1690 1700
TLRYLIQKLE QTTPEYYKTL HKTTKEQLET INKVNTQPEG KFIIDKNKFD
1710 1720 1730 1740 1750
PGHWALSQVG GSRLVDYAKY IYDTLIPWHA PIYGKETVEF KDDTKCVFCK
1760 1770 1780 1790 1800
EKIDMVTYVC NTAKFNEHLA CTCRAAAVVN DTNVVCVYCD TPMVPVFNRQ
1810 1820 1830 1840 1850
PQSIYNWMAA LLSAAKDVLY DPINSLPETW NKEKFRTNMR MLAISAVTAL
1860 1870 1880 1890 1900
VMYTSINFAD IVFKKSTYNA FYKYVGELPH KVLTVGEQVY LMTKSGVKFL
1910 1920 1930 1940 1950
LCRNQDTEFF IPAKDDVENA QGEFDVLPIE PGEIMDIELG GGSGFKVVGH
1960 1970 1980 1990 2000
SKKASRKAQK INREEFSKIS DTASTSSDES DASAHKHEKH GVEFFSWLRV
2010 2020 2030 2040 2050
GEREKCQHDG AIIEKILRKR MSELSCTLDG KLVLYAVEED ETEIVLVVEK
2060 2070 2080 2090 2100
CCSACLLLDD RIVLKISDFF NQNSPIWKQH IDEGLLEYVP ELYVKFLMEC
2110 2120 2130 2140 2150
RNGANVERTV HNEKYSKWQN QILSQITTKF MEAVHVVWVF LTENYKMFLS
2160 2170 2180 2190 2200
GCAIIFCAYK GYKWYKNDEG IIEPVDPQGS YVSASQRTIR SGITRTINNS
2210 2220 2230 2240 2250
YLKGTQAHGP YLKEPNQAVL ARAARIRKNY ITMQLNSIPI WGIGLYGHTV
2260 2270 2280 2290 2300
LMTRHNWHWL KFAARTMNLD ALTIMSRGSD NVVVKFSEVL EVLDLPEVEH
2310 2320 2330 2340 2350
VLIELPKKGL QCFSNIRTYF TKGLDEKGEA TNPQLDELAY YIDVLDGLTL
2360 2370 2380 2390 2400
KSTAISAIGK GEPVQTTFTI NSKTEDYLNS IPSQYDWIIT PTQAKGMCLT
2410 2420 2430 2440 2450
AFLDKQGNIL GFHVAGNARL RQGYVAPIFR ELIPDAGIAS VVTEPEGPST
2460 2470 2480 2490 2500
ENLTYMYSVI DAPYHTFQSK IVPSVLQSEA YDPEKEPCIQ SRTDPRYTHG
2510 2520 2530 2540 2550
ADPLTDGVAT IGQPTKPLND EILMLAYESV RDELLGVLPP PYVQPPVSIR
2560 2570 2580 2590 2600
EAITAERAPI SSSMNLATSA GYPLAGRGSR EKKKSDYILG GQLKASVHNK
2610 2620 2630 2640 2650
INKAYVQRTN GIRPPCVYWA HLKDELRPSE KLRRFGGTRV FSVPPLELVL
2660 2670 2680 2690 2700
NSRRFLLPFM DAFQSFPIEA HHAIGLNPNS GDWRRLRDTL LEKGPCLLQM
2710 2720 2730 2740 2750
DYKNYSDAIP KECVAKAFHI IVDYYRKWHC STVEIENALK TLFLDTADAE
2760 2770 2780 2790 2800
LLVYGDVFKV NNGVLAGHPM TSVVNSVVNL ILMNYMWIKI TRRRASEFFK
2810 2820 2830 2840 2850
LTYIIVMGDD VVISLPKQLT EEFDCRKICA EFAKYDIKVT DSEKNLTGEP
2860 2870 2880 2890 2900
KPYDSFDKFE FLSRGFSDCD AYPDITFAPV KTIALFDCPL WISKGQDEEE
2910 2920 2930 2940 2950
QTIQAIQAGL LLAFDHGPEF FGKYKQLLLE GTSVPTYNYF TWSELYSLFH
2960 2970 2980 2990 3000
GDVYSSGEQS VQTNNEHGIV LKKIPMVLSY IYADSMCIGS DAEIGEEKGA
3010 3020 3030 3040 3050
LEAQAMFQKK QLRAINISKQ AEHYLTAAED IYDSLDKVKN LEKWRCGCKY
3060 3070 3080
DCMREVERRM LEKVGKSMNA LLEENAKEPL IEMLE
Length:3,085
Mass (Da):345,803
Last modified:August 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i23FC9600DBF71531
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB000906 Genomic RNA Translation: BAA25371.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T00327

NCBI Reference Sequences

More...
RefSeqi
NP_620559.1, NC_003781.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
944329

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vg:944329

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB000906 Genomic RNA Translation: BAA25371.1
PIRiT00327
RefSeqiNP_620559.1, NC_003781.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Genome annotation databases

GeneIDi944329
KEGGivg:944329

Family and domain databases

CDDicd00205, rhv_like, 1 hit
Gene3Di2.60.120.20, 3 hits
3.30.70.270, 1 hit
InterProiView protein in InterPro
IPR014872, Dicistrovirus_capsid-polyPr_C
IPR043502, DNA/RNA_pol_sf
IPR000605, Helicase_SF3_ssDNA/RNA_vir
IPR014759, Helicase_SF3_ssRNA_vir
IPR044067, PCV_3C_PRO
IPR009003, Peptidase_S1_PA
IPR001676, Picornavirus_capsid
IPR043128, Rev_trsase/Diguanyl_cyclase
IPR033703, Rhv-like
IPR001205, RNA-dir_pol_C
IPR007094, RNA-dir_pol_PSvirus
IPR029053, Viral_coat
PfamiView protein in Pfam
PF08762, CRPV_capsid, 1 hit
PF00680, RdRP_1, 1 hit
PF00073, Rhv, 1 hit
PF00910, RNA_helicase, 1 hit
SUPFAMiSSF50494, SSF50494, 1 hit
SSF56672, SSF56672, 1 hit
PROSITEiView protein in PROSITE
PS51874, PCV_3C_PRO, 1 hit
PS50507, RDRP_SSRNA_POS, 1 hit
PS51218, SF3_HELICASE_2, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO70710_IFVS
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O70710
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: June 2, 2021
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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