UniProtKB - O70511 (ANK3_RAT)
(max 400 entries)x
Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>
Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)
- BLAST>sp|O70511|ANK3_RAT Ankyrin-3 OS=Rattus norvegicus OX=10116 GN=Ank3 PE=1 SV=3 MAHAASQLKKNRDLEINAEEETEKKKKHRKRSRDRKKKSDANASYLRAARAGHLEKALDY IKNGVDVNICNQNGLNALHLASKEGHVEVVSELLQREANVDAATKKGNTALHIASLAGQA EVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVRFLLDNGASQSLATEDGFTPLAVA LQQGHDQVVSLLLENDTKGKVRLPALHIAARKDDTKAAALLLQNDTNADIESKMVVNRAT ESGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRGA KIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPILSKTKNGLSPLHMATQGDHLNCVQL LLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKKNR IRVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHM AARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSG YTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGKLEVASLLLQKSASPD AAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIAAKKNQMDIATSLLE YGADANAVTRQGIASVHLAAQEGHVDMVSLLLSRNANVNLSNKSGLTPLHLAAQEDRVNV AEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQHSAKVNAKTKNGYTPLHQAAQ QGHTHIINVLLQNNASPNELTVNGNTALAIARRLGYISVVDTLKVVTEEIMTTTTITEKH KMNVPETMNEVLDMSDDEVGKASAPEKLSDGEYISDGEEGEDAITGDTDKYLGPQDLKEL GDDSLPAEGYVGFSLGARSASLRSFSSDRSYTLNRSSYARDSMMIEELLVPSKEQHLPFT REFDSDSLRHYSWAADTLDNVNLVSSPVHSGFLVSFMVDARGGSMRGSRHHGMRIIIPPR KCTAPTRITCRLVKRHKLANPPPMVEGEGLASRLVEMGPAGAQFLGPVIVEIPHFGSMRG KERELIVLRSENGETWKEHQFDSKNEDLSELLNGMDEELDSPEELGTKRICRIITKDFPQ YFAVVSRIKQESNQIGPEGGILSSTTVPLVQASFPEGALTKRIRVGLQAQPVPEETVKKI LGNKATFSPIVTVEPRRRKFHKPITMTIPVPPPSGEGVSNGYKGDTTPSLRLLCSITGGT SPAQWEDITGTTPLTFIKDCVSFTTNVSARFWLADCHQVLETVGLASQLYRELICVPYMA KFVVFAKTNDPVESSLRCFCMTDDRVDKTLEQQENFEEVARSKDIEVLEGKPIYVDCYGN LAPLTKGGQQLVFNFYSFKENRLPFSIKVRDTSQEPCGRLSFLKEPKTTKGLPQTAVCNL NITLPAHKKAEKADRRQSFTSLALRKRYSYLTEPSMKTVERSSGTARSLPTTYSHKPFFS TRPYQSWTTTPITVPGPAKSGSLSSSPSNTPSASPLKSIWSVSTPSPIKSTLGASTTSSV KSISDVASPIRSFRTISSPIRTVASPSPYNTQVASGTLGRVPTITEATPIKGVAPNSTLS SRTSPVTTAGSLLEKSSITMTPPASPKANITMYSSSLPFKSIITSAAPLISSPLKSVVSP TKSAADVISTAKAAMASTLSSPLKQMSGHAEVALVNGSVSPLKYPSSSALINGCKATATL QDKISTATNAVSSVVSAAPDTVEKALSTTTAMPFSPLRSYVSAAAPSAFQSLRAPSASAL YNSLGPSVGVTTSSVTSSIITVPVYSVGNVLAEPALKKLPDSNSLTKSAAALLSPIKTLT TETRPQPHFNRTSSPVKSSLFLASSALKPSVPSSLSSSQEILKDVAEMKEDLMRMTAILQ TDVPEEKPFQTDLPREGRIDDEEPFKIVEKVKEDLVKVSEILKKDVCVESKGPPKSPKSD KGHSPEDDWTEFSSEEIREARQAAASHAPSLPERVHGKANLTRVIDYLTNDIGSSSLTNL KYKFEEAKKEGEERQKRILKPAMALQEHKLKMPPASMRPSTSEKELCKMADSFFGTDAIL ESPDDFSQHDQDKSPLSDSGFETRSEKTPSAPQSAESTGPKPLFHEVPIPPVITETRTEV VHVIRSYEPSTGEIPQSQPEDPVSPKPPPTFMELEPKPTALSIKEKVKAFQMKASSEEED HSRVLSKGMRVKEETHITTTTRMVYHSPPGSECASERIEETMSVHDIMKAFQSGRDPSKE LAGLFEHKSAMSPDVAKSAAETSAQHAEKDNQMKPKLERIIEVHIEKGPQSPCERTDIRM AIVADHLGLSWTELARELNFSVDEINQIRVENPNSLISQSFMLLKKWVTRDGKNATTDAL TSVLTKINRIDIVTLLEGPIFDYGNISGTRSFADENNVFHDPVDGWQNETPSGSLESPAQ ARRITGGLLDRLDDSSDQVRDPITSYLTGEAGKFEANGNHAEVIPEAKAKAYFPESQNDI GKQSIKENLKPKTHGCGRAEEPVSPLTAYQKSLEETSKLVIEDAPKPCVPVGMKKMTRTP ADGKARLNLQEEEGSARSEPKQGEGYKVKTKKEIRNVEKKAH
- Align
Protein
Ankyrin-3
Gene
Ank3
Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:
Annotation score:5 out of 5
<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>Select a section on the left to see content.
<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni
Membrane-cytoskeleton linker. May participate in the maintenance/targeting of ion channels and cell adhesion molecules at the nodes of Ranvier and axonal initial segments. In skeletal muscle, required for costamere localization of DMD and betaDAG1 (By similarity). Regulates KCNA1 channel activity in function of dietary Mg2+ levels, and thereby contributes to the regulation of renal Mg2+ reabsorption (By similarity).By similarity
<p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More...</a></p> Manual assertion inferred from sequence similarity toi
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni
- cadherin binding Source: BHF-UCL <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ipi">GO evidence code guide</a></p> Inferred from physical interactioni
- cytoskeletal protein binding Source: BHF-UCL <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ipi">GO evidence code guide</a></p> Inferred from physical interactioni
- ion channel binding Source: BHF-UCL <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ipi">GO evidence code guide</a></p> Inferred from physical interactioni
- protein binding, bridging Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- spectrin binding Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi
- cellular response to magnesium ion Source: UniProtKB
- magnesium ion homeostasis Source: UniProtKB
- membrane assembly Source: BHF-UCL <p>Inferred from Genetic Interaction</p> <p>Used to describe “traditional” genetic interactions such as suppressors and synthetic lethals as well as other techniques such as functional complementation, rescue experiments, or inferences about a gene drawn from the phenotype of a mutation in a different gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#igi">GO evidence code guide</a></p> Inferred from genetic interactioni
- negative regulation of delayed rectifier potassium channel activity Source: UniProtKB
- neuromuscular junction development Source: RGD <p>Inferred from Expression Pattern</p> <p>Covers cases where the annotation is inferred from the timing or location of expression of a gene.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#iep">GO evidence code guide</a></p> Inferred from expression patterni
- positive regulation of cation channel activity Source: BHF-UCL <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of cell communication by electrical coupling Source: RGD <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of gene expression Source: BHF-UCL <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of homotypic cell-cell adhesion Source: RGD <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of membrane depolarization during cardiac muscle cell action potential Source: BHF-UCL <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of membrane potential Source: BHF-UCL <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of protein targeting to membrane Source: RGD <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of sodium ion transmembrane transporter activity Source: BHF-UCL <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of sodium ion transport Source: BHF-UCL <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- protein localization to plasma membrane Source: BHF-UCL <p>Inferred from Mutant Phenotype</p> <p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- regulation of potassium ion transport Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- signal transduction Source: InterPro
<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi | Recommended name: Ankyrin-3Short name: ANK-3 Alternative name(s): Ankyrin-G |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi | Name:Ank3 |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>Organismi | Rattus norvegicus (Rat) |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri | 10116 [NCBI] |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineagei | cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
| <p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi |
|
Organism-specific databases
Rat genome database More...RGDi | 620157 Ank3 |
<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi
Plasma membrane
Lysosome
- Lysosome By similarity
Cytoskeleton
- cytoskeleton By similarity
Other locations
Note: In root dorsal ganglia, predominantly located in the axolemma of the axon proximal segments. Also associated with the plasma membrane in neuron cell bodies, although at a lower level than in the axon proximal segment. Isoform 1 is restricted to the axolemma of the axon proximal segment. Isoforms containing the muscle-specific 76 amino-acid insertion localize to the sarcolemma and on the postsynaptic membrane of neuromuscular junctions. Isoform 7 interacts with PLEC and FLNC through its muscle-specific C-terminal sequence.
Cytoskeleton
- spectrin-associated cytoskeleton Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
Endoplasmic reticulum
- sarcoplasmic reticulum Source: RGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
Lysosome
- lysosome Source: UniProtKB-SubCell
Plasma Membrane
- plasma membrane Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- postsynaptic membrane Source: RGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- sarcolemma Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- T-tubule Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
Other locations
- axon initial segment Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- cell surface Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- costamere Source: BHF-UCL <p>Traceable Author Statement</p> <p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#tas">GO evidence code guide</a></p> Traceable author statementi
- dendrite Source: RGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- intercalated disc Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- neuromuscular junction Source: RGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- neuron projection Source: RGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- node of Ranvier Source: ARUK-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- Z disc Source: RGD <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti
Cell junction, Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Lysosome, Membrane, Postsynaptic cell membrane, Synapse<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi
Molecule processing
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_0000429632 | 1 – 2622 | Ankyrin-3Add BLAST | 2622 |
Amino acid modifications
| Feature key | Position(s) | DescriptionActions | Graphical view | Length | |
|---|---|---|---|---|---|
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 39 | PhosphoserineBy similarity <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More...</a></p> Manual assertion inferred from sequence similarity toi | 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 631 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 855 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 869 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 875 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 921 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 924 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 930 | PhosphoserineBy similarity <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More...</a></p> Manual assertion inferred from sequence similarity toi | 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 965 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 967 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 1121 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 1458 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 1469 | PhosphoserineBy similarity <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More...</a></p> Manual assertion inferred from sequence similarity toi | 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 1621 | PhosphoserineBy similarity <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More...</a></p> Manual assertion inferred from sequence similarity toi | 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 1624 | PhosphoserineBy similarity <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More...</a></p> Manual assertion inferred from sequence similarity toi | 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 1984 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 2102 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 2114 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 2117 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 2457 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 2475 | PhosphoserineBy similarity <p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More...</a></p> Manual assertion inferred from sequence similarity toi | 1 | ||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 2544 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| Isoform 4 (identifier: O70511-4) | |||||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 851 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| Isoform 5 (identifier: O70511-5) | |||||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 851 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
| Isoform 2 (identifier: O70511-2) | |||||
| <p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei | 1679 | PhosphoserineCombined sources <p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
| 1 | ||
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi
PhosphoproteinProteomic databases
PaxDb, a database of protein abundance averages across all three domains of life More...PaxDbi | O70511 |
PRoteomics IDEntifications database More...PRIDEi | O70511 |
PTM databases
iPTMnet integrated resource for PTMs in systems biology context More...iPTMneti | O70511 |
Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat. More...PhosphoSitePlusi | O70511 |
SwissPalm database of S-palmitoylation events More...SwissPalmi | O70511 |
<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni
<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi
Expressed at highest levels in brain and testis, followed by skin, kidney, liver and spleen. Isoforms 2, 3, 4, 5, 6 and 7 may be specifically expressed in muscle tissues, including heart and skeletal muscle (extensor digitorum longus) (at protein level) (PubMed:11796721).3 Publications
<p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
- Ref.2"Identification of Ank(G107), a muscle-specific ankyrin-G isoform."
Gagelin C., Constantin B., Deprette C., Ludosky M.A., Recouvreur M., Cartaud J., Cognard C., Raymond G., Kordeli E.
J. Biol. Chem. 277:12978-12987(2002) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 7), SUBCELLULAR LOCATION, TISSUE SPECIFICITY. - Ref.3"Ankyrin-G in skeletal muscle: tissue-specific alternative splicing contributes to the complexity of the sarcolemmal cytoskeleton."
Hopitzan A.A., Baines A.J., Ludosky M.A., Recouvreur M., Kordeli E.
Exp. Cell Res. 309:86-98(2005) [PubMed] [Europe PMC] [Abstract]Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 2; 3; 4; 5; 6 AND 7), SUBCELLULAR LOCATION, TISSUE SPECIFICITY. - Ref.4"Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C."
Maiweilidan Y., Klauza I., Kordeli E.
Exp. Cell Res. 317:724-736(2011) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH PLEC AND FLNC, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni
<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei
May be a constituent of a NFASC/NRCAM/ankyrin G complex. Interacts with RHBG. Directly interacts with DMD and betaDAG1; this interaction does not interfere with DMD-binding and is required for DMD and betaDAG1 retention at costameres. Interacts (via N-terminal ANK repeats) with SCHIP1 isoform 7 (via C-terminus); this interaction is required for the localization at axon initial segments (AISs) and nodes of Ranvier (NRs) (By similarity). Interacts with PLEC and FLNC (PubMed:21223964). Interacts with KCNA1; this inhibits channel activity (By similarity). Interacts (via ANK repeats) with IQCJ-SCHIP1; required for IQCJ-SCHIP1 localization at axon initial segments (AIS) and nodes of Ranvier (By similarity). Interacts with SCHIP1 (By similarity).By similarity
<p>Manually curated information which has been propagated from a related experimentally characterized protein.</p> <p><a href="/manual/evidences#ECO:0000250">More...</a></p> Manual assertion inferred from sequence similarity toi
1 Publication<p>Manually curated information for which there is published experimental evidence.</p> <p><a href="/manual/evidences#ECO:0000269">More...</a></p> Manual assertion based on experiment ini
- Ref.4"Novel interactions of ankyrins-G at the costameres: the muscle-specific Obscurin/Titin-Binding-related Domain (OTBD) binds plectin and filamin C."
Maiweilidan Y., Klauza I., Kordeli E.
Exp. Cell Res. 317:724-736(2011) [PubMed] [Europe PMC] [Abstract]Cited for: INTERACTION WITH PLEC AND FLNC, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi
| With | Entry | #Exp. | IntAct | Notes |
|---|---|---|---|---|
| FLNC | Q14315 | 2 | EBI-9663485,EBI-489954 | From Homo sapiens. |
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni
- cadherin binding Source: BHF-UCL <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ipi">GO evidence code guide</a></p> Inferred from physical interactioni
- cytoskeletal protein binding Source: BHF-UCL <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ipi">GO evidence code guide</a></p> Inferred from physical interactioni
- ion channel binding Source: BHF-UCL <p>Inferred from Physical Interaction</p> <p>Covers physical interactions between the gene product of interest and another molecule (or ion, or complex).</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ipi">GO evidence code guide</a></p> Inferred from physical interactioni
- protein binding, bridging Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- spectrin binding Source: BHF-UCL <p>Inferred from Direct Assay</p> <p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p> <p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
Protein-protein interaction databases
The Biological General Repository for Interaction Datasets (BioGrid) More...BioGridi | 262995, 3 interactors |
CORUM comprehensive resource of mammalian protein complexes More...CORUMi | O70511 |
Database of interacting proteins More...DIPi | DIP-60342N |
Protein interaction database and analysis system More...IntActi | O70511, 7 interactors |
STRING: functional protein association networks More...STRINGi | 10116.ENSRNOP00000043687 |
<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei
3D structure databases
SWISS-MODEL Repository - a database of annotated 3D protein structure models More...SMRi | O70511 |
Database of comparative protein structure models More...ModBasei | Search... |
MobiDB: a database of protein disorder and mobility annotations More...MobiDBi | Search... |
<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi
Domains and Repeats
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 73 – 102 | ANK 1Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 106 – 135 | ANK 2Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 139 – 168 | ANK 3Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 172 – 201 | ANK 4Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 203 – 230 | ANK 5Add BLAST | 28 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 242 – 271 | ANK 6Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 275 – 304 | ANK 7Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 308 – 337 | ANK 8Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 341 – 370 | ANK 9Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 374 – 403 | ANK 10Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 407 – 436 | ANK 11Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 440 – 469 | ANK 12Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 473 – 502 | ANK 13Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 506 – 535 | ANK 14Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 539 – 568 | ANK 15Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 572 – 601 | ANK 16Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 605 – 634 | ANK 17Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 638 – 667 | ANK 18Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 671 – 700 | ANK 19Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 704 – 733 | ANK 20Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 737 – 766 | ANK 21Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 770 – 799 | ANK 22Add BLAST | 30 | |
| <p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati | 803 – 832 | ANK 23Add BLAST | 30 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 992 – 1147 | ZU5 1PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 156 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 1149 – 1296 | ZU5 2PROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 148 | |
| <p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini | 2336 – 2420 | DeathPROSITE-ProRule annotation <p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p> <p><a href="/manual/evidences#ECO:0000255">More...</a></p> Manual assertion according to rulesi Add BLAST | 85 |
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini
ANK repeat, RepeatPhylogenomic databases
evolutionary genealogy of genes: Non-supervised Orthologous Groups More...eggNOGi | KOG4177 Eukaryota COG0666 LUCA |
The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms More...HOGENOMi | HOG000012873 |
The HOVERGEN Database of Homologous Vertebrate Genes More...HOVERGENi | HBG024337 |
KEGG Orthology (KO) More...KOi | K10380 |
Family and domain databases
Conserved Domains Database More...CDDi | cd00204 ANK, 7 hits cd08803 Death_ank3, 1 hit |
Gene3D Structural and Functional Annotation of Protein Families More...Gene3Di | 1.25.40.20, 3 hits |
Integrated resource of protein families, domains and functional sites More...InterProi | View protein in InterPro IPR037971 Ank3_Death IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR011029 DEATH-like_dom_sf IPR000488 Death_domain IPR000906 ZU5_dom |
Pfam protein domain database More...Pfami | View protein in Pfam PF00023 Ank, 2 hits PF12796 Ank_2, 6 hits PF13606 Ank_3, 1 hit PF00531 Death, 1 hit PF00791 ZU5, 1 hit |
Protein Motif fingerprint database; a protein domain database More...PRINTSi | PR01415 ANKYRIN |
Simple Modular Architecture Research Tool; a protein domain database More...SMARTi | View protein in SMART SM00248 ANK, 22 hits SM00005 DEATH, 1 hit SM00218 ZU5, 1 hit |
Superfamily database of structural and functional annotation More...SUPFAMi | SSF47986 SSF47986, 1 hit SSF48403 SSF48403, 3 hits |
PROSITE; a protein domain and family database More...PROSITEi | View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 21 hits PS50017 DEATH_DOMAIN, 1 hit PS51145 ZU5, 2 hits |
<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (7)i
<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.
This entry describes 7 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basketAdded to basket
Isoform 1 (identifier: O70511-1) [UniParc]FASTAAdd to basketAdded to basketShow »
Also known as: AnkG270
This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
10 20 30 40 50
MAHAASQLKK NRDLEINAEE ETEKKKKHRK RSRDRKKKSD ANASYLRAAR
60 70 80 90 100
AGHLEKALDY IKNGVDVNIC NQNGLNALHL ASKEGHVEVV SELLQREANV
110 120 130 140 150
DAATKKGNTA LHIASLAGQA EVVKVLVTNG ANVNAQSQNG FTPLYMAAQE
160 170 180 190 200
NHLEVVRFLL DNGASQSLAT EDGFTPLAVA LQQGHDQVVS LLLENDTKGK
210 220 230 240 250
VRLPALHIAA RKDDTKAAAL LLQNDTNADI ESKMVVNRAT ESGFTPLHIA
260 270 280 290 300
AHYGNINVAT LLLNRAAAVD FTARNDITPL HVASKRGNAN MVKLLLDRGA
310 320 330 340 350
KIDAKTRDGL TPLHCGARSG HEQVVEMLLD RAAPILSKTK NGLSPLHMAT
360 370 380 390 400
QGDHLNCVQL LLQHNVPVDD VTNDYLTALH VAAHCGHYKV AKVLLDKKAN
410 420 430 440 450
PNAKALNGFT PLHIACKKNR IRVMELLLKH GASIQAVTES GLTPIHVAAF
460 470 480 490 500
MGHVNIVSQL MHHGASPNTT NVRGETALHM AARSGQAEVV RYLVQDGAQV
510 520 530 540 550
EAKAKDDQTP LHISARLGKA DIVQQLLQQG ASPNAATTSG YTPLHLSARE
560 570 580 590 600
GHEDVAAFLL DHGASLSITT KKGFTPLHVA AKYGKLEVAS LLLQKSASPD
610 620 630 640 650
AAGKSGLTPL HVAAHYDNQK VALLLLDQGA SPHAAAKNGY TPLHIAAKKN
660 670 680 690 700
QMDIATSLLE YGADANAVTR QGIASVHLAA QEGHVDMVSL LLSRNANVNL
710 720 730 740 750
SNKSGLTPLH LAAQEDRVNV AEVLVNQGAH VDAQTKMGYT PLHVGCHYGN
760 770 780 790 800
IKIVNFLLQH SAKVNAKTKN GYTPLHQAAQ QGHTHIINVL LQNNASPNEL
810 820 830 840 850
TVNGNTALAI ARRLGYISVV DTLKVVTEEI MTTTTITEKH KMNVPETMNE
860 870 880 890 900
VLDMSDDEVG KASAPEKLSD GEYISDGEEG EDAITGDTDK YLGPQDLKEL
910 920 930 940 950
GDDSLPAEGY VGFSLGARSA SLRSFSSDRS YTLNRSSYAR DSMMIEELLV
960 970 980 990 1000
PSKEQHLPFT REFDSDSLRH YSWAADTLDN VNLVSSPVHS GFLVSFMVDA
1010 1020 1030 1040 1050
RGGSMRGSRH HGMRIIIPPR KCTAPTRITC RLVKRHKLAN PPPMVEGEGL
1060 1070 1080 1090 1100
ASRLVEMGPA GAQFLGPVIV EIPHFGSMRG KERELIVLRS ENGETWKEHQ
1110 1120 1130 1140 1150
FDSKNEDLSE LLNGMDEELD SPEELGTKRI CRIITKDFPQ YFAVVSRIKQ
1160 1170 1180 1190 1200
ESNQIGPEGG ILSSTTVPLV QASFPEGALT KRIRVGLQAQ PVPEETVKKI
1210 1220 1230 1240 1250
LGNKATFSPI VTVEPRRRKF HKPITMTIPV PPPSGEGVSN GYKGDTTPSL
1260 1270 1280 1290 1300
RLLCSITGGT SPAQWEDITG TTPLTFIKDC VSFTTNVSAR FWLADCHQVL
1310 1320 1330 1340 1350
ETVGLASQLY RELICVPYMA KFVVFAKTND PVESSLRCFC MTDDRVDKTL
1360 1370 1380 1390 1400
EQQENFEEVA RSKDIEVLEG KPIYVDCYGN LAPLTKGGQQ LVFNFYSFKE
1410 1420 1430 1440 1450
NRLPFSIKVR DTSQEPCGRL SFLKEPKTTK GLPQTAVCNL NITLPAHKKA
1460 1470 1480 1490 1500
EKADRRQSFT SLALRKRYSY LTEPSMKTVE RSSGTARSLP TTYSHKPFFS
1510 1520 1530 1540 1550
TRPYQSWTTT PITVPGPAKS GSLSSSPSNT PSASPLKSIW SVSTPSPIKS
1560 1570 1580 1590 1600
TLGASTTSSV KSISDVASPI RSFRTISSPI RTVASPSPYN TQVASGTLGR
1610 1620 1630 1640 1650
VPTITEATPI KGVAPNSTLS SRTSPVTTAG SLLEKSSITM TPPASPKANI
1660 1670 1680 1690 1700
TMYSSSLPFK SIITSAAPLI SSPLKSVVSP TKSAADVIST AKAAMASTLS
1710 1720 1730 1740 1750
SPLKQMSGHA EVALVNGSVS PLKYPSSSAL INGCKATATL QDKISTATNA
1760 1770 1780 1790 1800
VSSVVSAAPD TVEKALSTTT AMPFSPLRSY VSAAAPSAFQ SLRAPSASAL
1810 1820 1830 1840 1850
YNSLGPSVGV TTSSVTSSII TVPVYSVGNV LAEPALKKLP DSNSLTKSAA
1860 1870 1880 1890 1900
ALLSPIKTLT TETRPQPHFN RTSSPVKSSL FLASSALKPS VPSSLSSSQE
1910 1920 1930 1940 1950
ILKDVAEMKE DLMRMTAILQ TDVPEEKPFQ TDLPREGRID DEEPFKIVEK
1960 1970 1980 1990 2000
VKEDLVKVSE ILKKDVCVES KGPPKSPKSD KGHSPEDDWT EFSSEEIREA
2010 2020 2030 2040 2050
RQAAASHAPS LPERVHGKAN LTRVIDYLTN DIGSSSLTNL KYKFEEAKKE
2060 2070 2080 2090 2100
GEERQKRILK PAMALQEHKL KMPPASMRPS TSEKELCKMA DSFFGTDAIL
2110 2120 2130 2140 2150
ESPDDFSQHD QDKSPLSDSG FETRSEKTPS APQSAESTGP KPLFHEVPIP
2160 2170 2180 2190 2200
PVITETRTEV VHVIRSYEPS TGEIPQSQPE DPVSPKPPPT FMELEPKPTA
2210 2220 2230 2240 2250
LSIKEKVKAF QMKASSEEED HSRVLSKGMR VKEETHITTT TRMVYHSPPG
2260 2270 2280 2290 2300
SECASERIEE TMSVHDIMKA FQSGRDPSKE LAGLFEHKSA MSPDVAKSAA
2310 2320 2330 2340 2350
ETSAQHAEKD NQMKPKLERI IEVHIEKGPQ SPCERTDIRM AIVADHLGLS
2360 2370 2380 2390 2400
WTELARELNF SVDEINQIRV ENPNSLISQS FMLLKKWVTR DGKNATTDAL
2410 2420 2430 2440 2450
TSVLTKINRI DIVTLLEGPI FDYGNISGTR SFADENNVFH DPVDGWQNET
2460 2470 2480 2490 2500
PSGSLESPAQ ARRITGGLLD RLDDSSDQVR DPITSYLTGE AGKFEANGNH
2510 2520 2530 2540 2550
AEVIPEAKAK AYFPESQNDI GKQSIKENLK PKTHGCGRAE EPVSPLTAYQ
2560 2570 2580 2590 2600
KSLEETSKLV IEDAPKPCVP VGMKKMTRTP ADGKARLNLQ EEEGSARSEP
2610 2620
KQGEGYKVKT KKEIRNVEKK AH
Length:2,622
Mass (Da):284,443
Last modified:July 9, 2014 - v3
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:iA17F304D792333F5
Isoform 2 (identifier: O70511-2) [UniParc]FASTAAdd to basketAdded to basket
Also known as: AnkG217
The sequence of this isoform differs from the canonical sequence as follows:
1-36: MAHAASQLKKNRDLEINAEEETEKKKKHRKRSRDRK → MSEEAKEKTAKPAHRKRKG
234-241: Missing.
858-878: Missing.
922-927: LRSFSS → PKISS
1466-2444: KRYSYLTEPS...ENNVFHDPVD → PQSPCERTDI...RAELAMSSLA
2601-2601: K → KDLRHSESDS...GPQERKQDDV
10 20 30 40 50
MSEEAKEKTA KPAHRKRKGK KSDANASYLR AARAGHLEKA LDYIKNGVDV
60 70 80 90 100
NICNQNGLNA LHLASKEGHV EVVSELLQRE ANVDAATKKG NTALHIASLA
110 120 130 140 150
GQAEVVKVLV TNGANVNAQS QNGFTPLYMA AQENHLEVVR FLLDNGASQS
160 170 180 190 200
LATEDGFTPL AVALQQGHDQ VVSLLLENDT KGKVRLPALH IAARKDDTKA
210 220 230 240 250
AALLLQNDTN ADIESKSGFT PLHIAAHYGN INVATLLLNR AAAVDFTARN
260 270 280 290 300
DITPLHVASK RGNANMVKLL LDRGAKIDAK TRDGLTPLHC GARSGHEQVV
310 320 330 340 350
EMLLDRAAPI LSKTKNGLSP LHMATQGDHL NCVQLLLQHN VPVDDVTNDY
360 370 380 390 400
LTALHVAAHC GHYKVAKVLL DKKANPNAKA LNGFTPLHIA CKKNRIRVME
410 420 430 440 450
LLLKHGASIQ AVTESGLTPI HVAAFMGHVN IVSQLMHHGA SPNTTNVRGE
460 470 480 490 500
TALHMAARSG QAEVVRYLVQ DGAQVEAKAK DDQTPLHISA RLGKADIVQQ
510 520 530 540 550
LLQQGASPNA ATTSGYTPLH LSAREGHEDV AAFLLDHGAS LSITTKKGFT
560 570 580 590 600
PLHVAAKYGK LEVASLLLQK SASPDAAGKS GLTPLHVAAH YDNQKVALLL
610 620 630 640 650
LDQGASPHAA AKNGYTPLHI AAKKNQMDIA TSLLEYGADA NAVTRQGIAS
660 670 680 690 700
VHLAAQEGHV DMVSLLLSRN ANVNLSNKSG LTPLHLAAQE DRVNVAEVLV
710 720 730 740 750
NQGAHVDAQT KMGYTPLHVG CHYGNIKIVN FLLQHSAKVN AKTKNGYTPL
760 770 780 790 800
HQAAQQGHTH IINVLLQNNA SPNELTVNGN TALAIARRLG YISVVDTLKV
810 820 830 840 850
VTEEIMTTTT ITEKHKMNVP ETMNEVLDMS DDEGEDAITG DTDKYLGPQD
860 870 880 890 900
LKELGDDSLP AEGYVGFSLG ARSASPKISS DRSYTLNRSS YARDSMMIEE
910 920 930 940 950
LLVPSKEQHL PFTREFDSDS LRHYSWAADT LDNVNLVSSP VHSGFLVSFM
960 970 980 990 1000
VDARGGSMRG SRHHGMRIII PPRKCTAPTR ITCRLVKRHK LANPPPMVEG
1010 1020 1030 1040 1050
EGLASRLVEM GPAGAQFLGP VIVEIPHFGS MRGKERELIV LRSENGETWK
1060 1070 1080 1090 1100
EHQFDSKNED LSELLNGMDE ELDSPEELGT KRICRIITKD FPQYFAVVSR
1110 1120 1130 1140 1150
IKQESNQIGP EGGILSSTTV PLVQASFPEG ALTKRIRVGL QAQPVPEETV
1160 1170 1180 1190 1200
KKILGNKATF SPIVTVEPRR RKFHKPITMT IPVPPPSGEG VSNGYKGDTT
1210 1220 1230 1240 1250
PSLRLLCSIT GGTSPAQWED ITGTTPLTFI KDCVSFTTNV SARFWLADCH
1260 1270 1280 1290 1300
QVLETVGLAS QLYRELICVP YMAKFVVFAK TNDPVESSLR CFCMTDDRVD
1310 1320 1330 1340 1350
KTLEQQENFE EVARSKDIEV LEGKPIYVDC YGNLAPLTKG GQQLVFNFYS
1360 1370 1380 1390 1400
FKENRLPFSI KVRDTSQEPC GRLSFLKEPK TTKGLPQTAV CNLNITLPAH
1410 1420 1430 1440 1450
KKAEKADRRQ SFTSLALRPQ SPCERTDIRM AIVADHLGLS WTELARELNF
1460 1470 1480 1490 1500
SVDEINQIRV ENPNSLISQS FMLLKKWVTR DGKNATTDAL TSVLTKINRI
1510 1520 1530 1540 1550
DIVTLLEGPI FDYGNISGTR SFADENNVFH DPVDGHPSFQ VELETPMGLY
1560 1570 1580 1590 1600
CTPPTPFQQD DHFSDNSSIE SPFRTPSRLS DGLMPSQGSI EHPAGGPPVV
1610 1620 1630 1640 1650
TAEDTSLEDS KMDDSVTVTE TADPLDVDES QLKDLCQSEC AHCWASVPGV
1660 1670 1680 1690 1700
PSGGPQAEPL RAQTRKVGVS SEQQEKGDSG PEEEMADDKV RSLFEDIQLE
1710 1720 1730 1740 1750
EVEAEEMTED EGQAILNRVP RAELAMSSLA GWQNETPSGS LESPAQARRI
1760 1770 1780 1790 1800
TGGLLDRLDD SSDQVRDPIT SYLTGEAGKF EANGNHAEVI PEAKAKAYFP
1810 1820 1830 1840 1850
ESQNDIGKQS IKENLKPKTH GCGRAEEPVS PLTAYQKSLE ETSKLVIEDA
1860 1870 1880 1890 1900
PKPCVPVGMK KMTRTPADGK ARLNLQEEEG SARSEPKDLR HSESDSSSEE
1910 1920 1930 1940 1950
ERRVTTRVIR RRVIIKGEEA KTIPGESVTE EQFTDEEGNL ITRKITRKVI
1960 1970 1980
RRIGPQERKQ DDVQGEGYKV KTKKEIRNVE KKAH
Note: The 76 amino-acid long sequence from Asp-1888 to Val-1963 is encoded by a muscle-specific exon.Combined sources
Show »<p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
- Ref.5"Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-631; SER-855; SER-869; SER-875; SER-921; SER-924; SER-965; SER-967; SER-1121; SER-1458; SER-1984; SER-2102; SER-2114; SER-2117; SER-2457 AND SER-2544, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1679 (ISOFORM 2), PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-851 (ISOFORMS 4 AND 5), IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Length:1,984
Mass (Da):216,577
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:i45C2EEA326E36AD5
Isoform 3 (identifier: O70511-3) [UniParc]FASTAAdd to basketAdded to basket
Also known as: AnkG197
The sequence of this isoform differs from the canonical sequence as follows:
1-36: MAHAASQLKKNRDLEINAEEETEKKKKHRKRSRDRK → MSEEAKEKTAKPAHRKRKG
234-241: Missing.
858-878: Missing.
922-927: LRSFSS → PKISS
1466-2328: Missing.
2601-2601: K → KQVKSPGEAF...GPQERKQDDV
10 20 30 40 50
MSEEAKEKTA KPAHRKRKGK KSDANASYLR AARAGHLEKA LDYIKNGVDV
60 70 80 90 100
NICNQNGLNA LHLASKEGHV EVVSELLQRE ANVDAATKKG NTALHIASLA
110 120 130 140 150
GQAEVVKVLV TNGANVNAQS QNGFTPLYMA AQENHLEVVR FLLDNGASQS
160 170 180 190 200
LATEDGFTPL AVALQQGHDQ VVSLLLENDT KGKVRLPALH IAARKDDTKA
210 220 230 240 250
AALLLQNDTN ADIESKSGFT PLHIAAHYGN INVATLLLNR AAAVDFTARN
260 270 280 290 300
DITPLHVASK RGNANMVKLL LDRGAKIDAK TRDGLTPLHC GARSGHEQVV
310 320 330 340 350
EMLLDRAAPI LSKTKNGLSP LHMATQGDHL NCVQLLLQHN VPVDDVTNDY
360 370 380 390 400
LTALHVAAHC GHYKVAKVLL DKKANPNAKA LNGFTPLHIA CKKNRIRVME
410 420 430 440 450
LLLKHGASIQ AVTESGLTPI HVAAFMGHVN IVSQLMHHGA SPNTTNVRGE
460 470 480 490 500
TALHMAARSG QAEVVRYLVQ DGAQVEAKAK DDQTPLHISA RLGKADIVQQ
510 520 530 540 550
LLQQGASPNA ATTSGYTPLH LSAREGHEDV AAFLLDHGAS LSITTKKGFT
560 570 580 590 600
PLHVAAKYGK LEVASLLLQK SASPDAAGKS GLTPLHVAAH YDNQKVALLL
610 620 630 640 650
LDQGASPHAA AKNGYTPLHI AAKKNQMDIA TSLLEYGADA NAVTRQGIAS
660 670 680 690 700
VHLAAQEGHV DMVSLLLSRN ANVNLSNKSG LTPLHLAAQE DRVNVAEVLV
710 720 730 740 750
NQGAHVDAQT KMGYTPLHVG CHYGNIKIVN FLLQHSAKVN AKTKNGYTPL
760 770 780 790 800
HQAAQQGHTH IINVLLQNNA SPNELTVNGN TALAIARRLG YISVVDTLKV
810 820 830 840 850
VTEEIMTTTT ITEKHKMNVP ETMNEVLDMS DDEGEDAITG DTDKYLGPQD
860 870 880 890 900
LKELGDDSLP AEGYVGFSLG ARSASPKISS DRSYTLNRSS YARDSMMIEE
910 920 930 940 950
LLVPSKEQHL PFTREFDSDS LRHYSWAADT LDNVNLVSSP VHSGFLVSFM
960 970 980 990 1000
VDARGGSMRG SRHHGMRIII PPRKCTAPTR ITCRLVKRHK LANPPPMVEG
1010 1020 1030 1040 1050
EGLASRLVEM GPAGAQFLGP VIVEIPHFGS MRGKERELIV LRSENGETWK
1060 1070 1080 1090 1100
EHQFDSKNED LSELLNGMDE ELDSPEELGT KRICRIITKD FPQYFAVVSR
1110 1120 1130 1140 1150
IKQESNQIGP EGGILSSTTV PLVQASFPEG ALTKRIRVGL QAQPVPEETV
1160 1170 1180 1190 1200
KKILGNKATF SPIVTVEPRR RKFHKPITMT IPVPPPSGEG VSNGYKGDTT
1210 1220 1230 1240 1250
PSLRLLCSIT GGTSPAQWED ITGTTPLTFI KDCVSFTTNV SARFWLADCH
1260 1270 1280 1290 1300
QVLETVGLAS QLYRELICVP YMAKFVVFAK TNDPVESSLR CFCMTDDRVD
1310 1320 1330 1340 1350
KTLEQQENFE EVARSKDIEV LEGKPIYVDC YGNLAPLTKG GQQLVFNFYS
1360 1370 1380 1390 1400
FKENRLPFSI KVRDTSQEPC GRLSFLKEPK TTKGLPQTAV CNLNITLPAH
1410 1420 1430 1440 1450
KKAEKADRRQ SFTSLALRPQ SPCERTDIRM AIVADHLGLS WTELARELNF
1460 1470 1480 1490 1500
SVDEINQIRV ENPNSLISQS FMLLKKWVTR DGKNATTDAL TSVLTKINRI
1510 1520 1530 1540 1550
DIVTLLEGPI FDYGNISGTR SFADENNVFH DPVDGWQNET PSGSLESPAQ
1560 1570 1580 1590 1600
ARRITGGLLD RLDDSSDQVR DPITSYLTGE AGKFEANGNH AEVIPEAKAK
1610 1620 1630 1640 1650
AYFPESQNDI GKQSIKENLK PKTHGCGRAE EPVSPLTAYQ KSLEETSKLV
1660 1670 1680 1690 1700
IEDAPKPCVP VGMKKMTRTP ADGKARLNLQ EEEGSARSEP KQVKSPGEAF
1710 1720 1730 1740 1750
TRMTACCYKD LRHSESDSSS EEERRVTTRV IRRRVIIKGE EAKTIPGESV
1760 1770 1780 1790 1800
TEEQFTDEEG NLITRKITRK VIRRIGPQER KQDDVQGEGY KVKTKKEIRN
VEKKAH
Note: The 76 amino-acid long sequence from Asp-1710 to Val-1785 is encoded by a muscle-specific exon.
Show »Length:1,806
Mass (Da):197,423
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:i6197309048CD689A
Isoform 4 (identifier: O70511-4) [UniParc]FASTAAdd to basketAdded to basket
Also known as: Ank130
The sequence of this isoform differs from the canonical sequence as follows:
1-880: MAHAASQLKK...GEYISDGEEG → MALPHS
922-927: LRSFSS → PKISS
1466-2444: KRYSYLTEPS...ENNVFHDPVD → PQSPCERTDI...RAELAMSSLA
2601-2601: K → KVKSPGEAFT...GPQERKQDDV
10 20 30 40 50
MALPHSEDAI TGDTDKYLGP QDLKELGDDS LPAEGYVGFS LGARSASPKI
60 70 80 90 100
SSDRSYTLNR SSYARDSMMI EELLVPSKEQ HLPFTREFDS DSLRHYSWAA
110 120 130 140 150
DTLDNVNLVS SPVHSGFLVS FMVDARGGSM RGSRHHGMRI IIPPRKCTAP
160 170 180 190 200
TRITCRLVKR HKLANPPPMV EGEGLASRLV EMGPAGAQFL GPVIVEIPHF
210 220 230 240 250
GSMRGKEREL IVLRSENGET WKEHQFDSKN EDLSELLNGM DEELDSPEEL
260 270 280 290 300
GTKRICRIIT KDFPQYFAVV SRIKQESNQI GPEGGILSST TVPLVQASFP
310 320 330 340 350
EGALTKRIRV GLQAQPVPEE TVKKILGNKA TFSPIVTVEP RRRKFHKPIT
360 370 380 390 400
MTIPVPPPSG EGVSNGYKGD TTPSLRLLCS ITGGTSPAQW EDITGTTPLT
410 420 430 440 450
FIKDCVSFTT NVSARFWLAD CHQVLETVGL ASQLYRELIC VPYMAKFVVF
460 470 480 490 500
AKTNDPVESS LRCFCMTDDR VDKTLEQQEN FEEVARSKDI EVLEGKPIYV
510 520 530 540 550
DCYGNLAPLT KGGQQLVFNF YSFKENRLPF SIKVRDTSQE PCGRLSFLKE
560 570 580 590 600
PKTTKGLPQT AVCNLNITLP AHKKAEKADR RQSFTSLALR PQSPCERTDI
610 620 630 640 650
RMAIVADHLG LSWTELAREL NFSVDEINQI RVENPNSLIS QSFMLLKKWV
660 670 680 690 700
TRDGKNATTD ALTSVLTKIN RIDIVTLLEG PIFDYGNISG TRSFADENNV
710 720 730 740 750
FHDPVDGHPS FQVELETPMG LYCTPPTPFQ QDDHFSDNSS IESPFRTPSR
760 770 780 790 800
LSDGLMPSQG SIEHPAGGPP VVTAEDTSLE DSKMDDSVTV TETADPLDVD
810 820 830 840 850
ESQLKDLCQS ECAHCWASVP GVPSGGPQAE PLRAQTRKVG VSSEQQEKGD
860 870 880 890 900
SGPEEEMADD KVRSLFEDIQ LEEVEAEEMT EDEGQAILNR VPRAELAMSS
910 920 930 940 950
LAGWQNETPS GSLESPAQAR RITGGLLDRL DDSSDQVRDP ITSYLTGEAG
960 970 980 990 1000
KFEANGNHAE VIPEAKAKAY FPESQNDIGK QSIKENLKPK THGCGRAEEP
1010 1020 1030 1040 1050
VSPLTAYQKS LEETSKLVIE DAPKPCVPVG MKKMTRTPAD GKARLNLQEE
1060 1070 1080 1090 1100
EGSARSEPKV KSPGEAFTRM TACCYKDLRH SESDSSSEEE RRVTTRVIRR
1110 1120 1130 1140 1150
RVIIKGEEAK TIPGESVTEE QFTDEEGNLI TRKITRKVIR RIGPQERKQD
1160 1170
DVQGEGYKVK TKKEIRNVEK KAH
Note: The 76 amino-acid long sequence from Asp-1077 to Val-1152 is encoded by a muscle-specific exon.Combined sources
Show »<p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
- Ref.5"Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-631; SER-855; SER-869; SER-875; SER-921; SER-924; SER-965; SER-967; SER-1121; SER-1458; SER-1984; SER-2102; SER-2114; SER-2117; SER-2457 AND SER-2544, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1679 (ISOFORM 2), PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-851 (ISOFORMS 4 AND 5), IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Length:1,173
Mass (Da):129,941
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:i9E0602541FE4FE65
Isoform 5 (identifier: O70511-5) [UniParc]FASTAAdd to basketAdded to basket
Also known as: AnkG128
The sequence of this isoform differs from the canonical sequence as follows:
1-880: MAHAASQLKK...GEYISDGEEG → MALPHS
922-927: LRSFSS → PKISS
1466-2444: KRYSYLTEPS...ENNVFHDPVD → PQSPCERTDI...RAELAMSSLA
2601-2601: K → KDLRHSESDS...GPQERKQDDV
10 20 30 40 50
MALPHSEDAI TGDTDKYLGP QDLKELGDDS LPAEGYVGFS LGARSASPKI
60 70 80 90 100
SSDRSYTLNR SSYARDSMMI EELLVPSKEQ HLPFTREFDS DSLRHYSWAA
110 120 130 140 150
DTLDNVNLVS SPVHSGFLVS FMVDARGGSM RGSRHHGMRI IIPPRKCTAP
160 170 180 190 200
TRITCRLVKR HKLANPPPMV EGEGLASRLV EMGPAGAQFL GPVIVEIPHF
210 220 230 240 250
GSMRGKEREL IVLRSENGET WKEHQFDSKN EDLSELLNGM DEELDSPEEL
260 270 280 290 300
GTKRICRIIT KDFPQYFAVV SRIKQESNQI GPEGGILSST TVPLVQASFP
310 320 330 340 350
EGALTKRIRV GLQAQPVPEE TVKKILGNKA TFSPIVTVEP RRRKFHKPIT
360 370 380 390 400
MTIPVPPPSG EGVSNGYKGD TTPSLRLLCS ITGGTSPAQW EDITGTTPLT
410 420 430 440 450
FIKDCVSFTT NVSARFWLAD CHQVLETVGL ASQLYRELIC VPYMAKFVVF
460 470 480 490 500
AKTNDPVESS LRCFCMTDDR VDKTLEQQEN FEEVARSKDI EVLEGKPIYV
510 520 530 540 550
DCYGNLAPLT KGGQQLVFNF YSFKENRLPF SIKVRDTSQE PCGRLSFLKE
560 570 580 590 600
PKTTKGLPQT AVCNLNITLP AHKKAEKADR RQSFTSLALR PQSPCERTDI
610 620 630 640 650
RMAIVADHLG LSWTELAREL NFSVDEINQI RVENPNSLIS QSFMLLKKWV
660 670 680 690 700
TRDGKNATTD ALTSVLTKIN RIDIVTLLEG PIFDYGNISG TRSFADENNV
710 720 730 740 750
FHDPVDGHPS FQVELETPMG LYCTPPTPFQ QDDHFSDNSS IESPFRTPSR
760 770 780 790 800
LSDGLMPSQG SIEHPAGGPP VVTAEDTSLE DSKMDDSVTV TETADPLDVD
810 820 830 840 850
ESQLKDLCQS ECAHCWASVP GVPSGGPQAE PLRAQTRKVG VSSEQQEKGD
860 870 880 890 900
SGPEEEMADD KVRSLFEDIQ LEEVEAEEMT EDEGQAILNR VPRAELAMSS
910 920 930 940 950
LAGWQNETPS GSLESPAQAR RITGGLLDRL DDSSDQVRDP ITSYLTGEAG
960 970 980 990 1000
KFEANGNHAE VIPEAKAKAY FPESQNDIGK QSIKENLKPK THGCGRAEEP
1010 1020 1030 1040 1050
VSPLTAYQKS LEETSKLVIE DAPKPCVPVG MKKMTRTPAD GKARLNLQEE
1060 1070 1080 1090 1100
EGSARSEPKD LRHSESDSSS EEERRVTTRV IRRRVIIKGE EAKTIPGESV
1110 1120 1130 1140 1150
TEEQFTDEEG NLITRKITRK VIRRIGPQER KQDDVQGEGY KVKTKKEIRN
VEKKAH
Note: The 76 amino-acid long sequence from Asp-1060 to Val-1135 is encoded by a muscle-specific exon.Combined sources
Show »<p>Manually validated information inferred from a combination of experimental and computational evidence.</p> <p><a href="/manual/evidences#ECO:0000244">More...</a></p> Manual assertion inferred from combination of experimental and computational evidencei
- Ref.5"Quantitative maps of protein phosphorylation sites across 14 different rat organs and tissues."
Lundby A., Secher A., Lage K., Nordsborg N.B., Dmytriyev A., Lundby C., Olsen J.V.
Nat. Commun. 3:876-876(2012) [PubMed] [Europe PMC] [Abstract]Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-631; SER-855; SER-869; SER-875; SER-921; SER-924; SER-965; SER-967; SER-1121; SER-1458; SER-1984; SER-2102; SER-2114; SER-2117; SER-2457 AND SER-2544, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1679 (ISOFORM 2), PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-851 (ISOFORMS 4 AND 5), IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Length:1,156
Mass (Da):128,067
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:i043E3872865D1117
Isoform 6 (identifier: O70511-6) [UniParc]FASTAAdd to basketAdded to basket
Also known as: AnkG109
The sequence of this isoform differs from the canonical sequence as follows:
1-880: MAHAASQLKK...GEYISDGEEG → MALPHS
922-927: LRSFSS → PKISS
1466-2328: Missing.
2601-2601: K → KVKSPGEAFT...GPQERKQDDV
10 20 30 40 50
MALPHSEDAI TGDTDKYLGP QDLKELGDDS LPAEGYVGFS LGARSASPKI
60 70 80 90 100
SSDRSYTLNR SSYARDSMMI EELLVPSKEQ HLPFTREFDS DSLRHYSWAA
110 120 130 140 150
DTLDNVNLVS SPVHSGFLVS FMVDARGGSM RGSRHHGMRI IIPPRKCTAP
160 170 180 190 200
TRITCRLVKR HKLANPPPMV EGEGLASRLV EMGPAGAQFL GPVIVEIPHF
210 220 230 240 250
GSMRGKEREL IVLRSENGET WKEHQFDSKN EDLSELLNGM DEELDSPEEL
260 270 280 290 300
GTKRICRIIT KDFPQYFAVV SRIKQESNQI GPEGGILSST TVPLVQASFP
310 320 330 340 350
EGALTKRIRV GLQAQPVPEE TVKKILGNKA TFSPIVTVEP RRRKFHKPIT
360 370 380 390 400
MTIPVPPPSG EGVSNGYKGD TTPSLRLLCS ITGGTSPAQW EDITGTTPLT
410 420 430 440 450
FIKDCVSFTT NVSARFWLAD CHQVLETVGL ASQLYRELIC VPYMAKFVVF
460 470 480 490 500
AKTNDPVESS LRCFCMTDDR VDKTLEQQEN FEEVARSKDI EVLEGKPIYV
510 520 530 540 550
DCYGNLAPLT KGGQQLVFNF YSFKENRLPF SIKVRDTSQE PCGRLSFLKE
560 570 580 590 600
PKTTKGLPQT AVCNLNITLP AHKKAEKADR RQSFTSLALR PQSPCERTDI
610 620 630 640 650
RMAIVADHLG LSWTELAREL NFSVDEINQI RVENPNSLIS QSFMLLKKWV
660 670 680 690 700
TRDGKNATTD ALTSVLTKIN RIDIVTLLEG PIFDYGNISG TRSFADENNV
710 720 730 740 750
FHDPVDGWQN ETPSGSLESP AQARRITGGL LDRLDDSSDQ VRDPITSYLT
760 770 780 790 800
GEAGKFEANG NHAEVIPEAK AKAYFPESQN DIGKQSIKEN LKPKTHGCGR
810 820 830 840 850
AEEPVSPLTA YQKSLEETSK LVIEDAPKPC VPVGMKKMTR TPADGKARLN
860 870 880 890 900
LQEEEGSARS EPKVKSPGEA FTRMTACCYK DLRHSESDSS SEEERRVTTR
910 920 930 940 950
VIRRRVIIKG EEAKTIPGES VTEEQFTDEE GNLITRKITR KVIRRIGPQE
960 970
RKQDDVQGEG YKVKTKKEIR NVEKKAH
Note: The 76 amino-acid long sequence from Asp-881 to Val-956 is encoded by a muscle-specific exon.
Show »Length:977
Mass (Da):108,785
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:i02844AE344A6561D
Isoform 7 (identifier: O70511-7) [UniParc]FASTAAdd to basketAdded to basket
Also known as: AnkG107
The sequence of this isoform differs from the canonical sequence as follows:
1-880: MAHAASQLKK...GEYISDGEEG → MALPHS
922-927: LRSFSS → PKISS
1466-2328: Missing.
2601-2601: K → KDLRHSESDS...GPQERKQDDV
10 20 30 40 50
MALPHSEDAI TGDTDKYLGP QDLKELGDDS LPAEGYVGFS LGARSASPKI
60 70 80 90 100
SSDRSYTLNR SSYARDSMMI EELLVPSKEQ HLPFTREFDS DSLRHYSWAA
110 120 130 140 150
DTLDNVNLVS SPVHSGFLVS FMVDARGGSM RGSRHHGMRI IIPPRKCTAP
160 170 180 190 200
TRITCRLVKR HKLANPPPMV EGEGLASRLV EMGPAGAQFL GPVIVEIPHF
210 220 230 240 250
GSMRGKEREL IVLRSENGET WKEHQFDSKN EDLSELLNGM DEELDSPEEL
260 270 280 290 300
GTKRICRIIT KDFPQYFAVV SRIKQESNQI GPEGGILSST TVPLVQASFP
310 320 330 340 350
EGALTKRIRV GLQAQPVPEE TVKKILGNKA TFSPIVTVEP RRRKFHKPIT
360 370 380 390 400
MTIPVPPPSG EGVSNGYKGD TTPSLRLLCS ITGGTSPAQW EDITGTTPLT
410 420 430 440 450
FIKDCVSFTT NVSARFWLAD CHQVLETVGL ASQLYRELIC VPYMAKFVVF
460 470 480 490 500
AKTNDPVESS LRCFCMTDDR VDKTLEQQEN FEEVARSKDI EVLEGKPIYV
510 520 530 540 550
DCYGNLAPLT KGGQQLVFNF YSFKENRLPF SIKVRDTSQE PCGRLSFLKE
560 570 580 590 600
PKTTKGLPQT AVCNLNITLP AHKKAEKADR RQSFTSLALR PQSPCERTDI
610 620 630 640 650
RMAIVADHLG LSWTELAREL NFSVDEINQI RVENPNSLIS QSFMLLKKWV
660 670 680 690 700
TRDGKNATTD ALTSVLTKIN RIDIVTLLEG PIFDYGNISG TRSFADENNV
710 720 730 740 750
FHDPVDGWQN ETPSGSLESP AQARRITGGL LDRLDDSSDQ VRDPITSYLT
760 770 780 790 800
GEAGKFEANG NHAEVIPEAK AKAYFPESQN DIGKQSIKEN LKPKTHGCGR
810 820 830 840 850
AEEPVSPLTA YQKSLEETSK LVIEDAPKPC VPVGMKKMTR TPADGKARLN
860 870 880 890 900
LQEEEGSARS EPKDLRHSES DSSSEEERRV TTRVIRRRVI IKGEEAKTIP
910 920 930 940 950
GESVTEEQFT DEEGNLITRK ITRKVIRRIG PQERKQDDVQ GEGYKVKTKK
960
EIRNVEKKAH
Note: The 76 amino-acid long sequence from Asp-864 to Val-939 is encoded by a muscle-specific exon.
Show »Length:960
Mass (Da):106,911
<p>The checksum is a form of redundancy check that is calculated
from the sequence. It is useful for tracking sequence updates.</p>
<p>It should be noted that while, in theory, two different sequences could
have the same checksum value, the likelihood that this would happen
is extremely low.</p>
<p>However UniProtKB may contain entries with identical sequences in case
of multiple genes (paralogs).</p>
<p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64)
using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1.
The algorithm is described in the ISO 3309 standard.
</p>
<p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br />
<strong>Cyclic redundancy and other checksums</strong><br />
<a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p>
Checksum:iF850EF67D120878A
Experimental Info
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 246 | P → S in AAC78143 (PubMed:9744885).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 635 | A → S in CAH19223 (PubMed:15953600).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 635 | A → S in CAH19224 (PubMed:15953600).Curated | 1 | |
| <p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti | 667 | A → P in AAC78143 (PubMed:9744885).Curated | 1 |
Alternative sequence
| Feature key | Position(s) | DescriptionActions | Graphical view | Length |
|---|---|---|---|---|
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055004 | 1 – 880 | MAHAA…DGEEG → MALPHS in isoform 4, isoform 5, isoform 6 and isoform 7. 2 Publications <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 880 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055005 | 1 – 36 | MAHAA…SRDRK → MSEEAKEKTAKPAHRKRKG in isoform 2 and isoform 3. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 36 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055006 | 234 – 241 | Missing in isoform 2 and isoform 3. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 8 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055007 | 858 – 878 | Missing in isoform 2 and isoform 3. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 21 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055008 | 922 – 927 | LRSFSS → PKISS in isoform 2, isoform 3, isoform 4, isoform 5, isoform 6 and isoform 7. 2 Publications <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 6 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055009 | 1466 – 2444 | KRYSY…HDPVD → PQSPCERTDIRMAIVADHLG LSWTELARELNFSVDEINQI RVENPNSLISQSFMLLKKWV TRDGKNATTDALTSVLTKIN RIDIVTLLEGPIFDYGNISG TRSFADENNVFHDPVDGHPS FQVELETPMGLYCTPPTPFQ QDDHFSDNSSIESPFRTPSR LSDGLMPSQGSIEHPAGGPP VVTAEDTSLEDSKMDDSVTV TETADPLDVDESQLKDLCQS ECAHCWASVPGVPSGGPQAE PLRAQTRKVGVSSEQQEKGD SGPEEEMADDKVRSLFEDIQ LEEVEAEEMTEDEGQAILNR VPRAELAMSSLA in isoform 2, isoform 4 and isoform 5. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 979 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055010 | 1466 – 2328 | Missing in isoform 3, isoform 6 and isoform 7. 2 Publications <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 863 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055011 | 2601 | K → KDLRHSESDSSSEEERRVTT RVIRRRVIIKGEEAKTIPGE SVTEEQFTDEEGNLITRKIT RKVIRRIGPQERKQDDV in isoform 2, isoform 5 and isoform 7. 2 Publications <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055012 | 2601 | K → KQVKSPGEAFTRMTACCYKD LRHSESDSSSEEERRVTTRV IRRRVIIKGEEAKTIPGESV TEEQFTDEEGNLITRKITRK VIRRIGPQERKQDDV in isoform 3. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 1 | |
| <p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_055013 | 2601 | K → KVKSPGEAFTRMTACCYKDL RHSESDSSSEEERRVTTRVI RRRVIIKGEEAKTIPGESVT EEQFTDEEGNLITRKITRKV IRRIGPQERKQDDV in isoform 4 and isoform 6. 1 Publication <p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p> <p><a href="/manual/evidences#ECO:0000303">More...</a></p> Manual assertion based on opinion ini
| 1 |
Sequence databases
| Select the link destinations: EMBL nucleotide sequence database More...EMBLiGenBank nucleotide sequence database More...GenBankiDNA Data Bank of Japan; a nucleotide sequence database More...DDBJiLinks Updated | AF102552 mRNA Translation: AAC78143.1 AJ428573 mRNA Translation: CAD21705.1 AJ812019 mRNA Translation: CAH19219.1 AJ812021 mRNA Translation: CAH19221.1 AJ812022 mRNA Translation: CAH19222.1 AJ812023 mRNA Translation: CAH19223.1 AJ812024 mRNA Translation: CAH19224.1 |
NCBI Reference Sequences More...RefSeqi | NP_001029156.1, NM_001033984.1 [O70511-1] NP_113993.1, NM_031805.1 [O70511-2] |
UniGene gene-oriented nucleotide sequence clusters More...UniGenei | Rn.211093 Rn.212410 |
Genome annotation databases
Database of genes from NCBI RefSeq genomes More...GeneIDi | 361833 |
KEGG: Kyoto Encyclopedia of Genes and Genomes More...KEGGi | rno:361833 |
UCSC genome browser More...UCSCi | RGD:620157 rat |
<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi
Alternative splicing<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi
| Protein | Similar proteins | Species | Score | Length | |
|---|---|---|---|---|---|
| O70511 | AnkyrinG (Fragment) | 287 | |||
| UPI000B7B0D07 | 2728 | ||||
| UPI0005F4BA5B | 2727 | ||||
| UPI000945A1A3 | 2723 | ||||
| UPI000A326714 | 2626 | ||||
| +3 | |||||
| O70511-2 | Ankyrin-3 | 1985 | |||
| Ankyrin-3 | 1963 | ||||
| UPI000A3105EA | 1726 | ||||
| UPI000A318322 | 1726 | ||||
| G5E8K5-2 | 1726 | ||||
| O70511-3 | AnkyrinG (Fragment) | 143 | |||
| Uncharacterized protein | 1807 | ||||
| Ankyrin-3 | 1807 | ||||
| Ankyrin 3 | 1759 | ||||
| Ankyrin 3 | 1759 | ||||
| +11 | |||||
| O70511-4 | Ankyrin-3 | 1174 | |||
| UPI000B4F7E70 | 1097 | ||||
| UPI000A306DC0 | 1094 | ||||
| UPI000A315465 | 1094 | ||||
| ankyrin-3 isoform X16 | 1087 | ||||
| +4 | |||||
| O70511-5 | Ankyrin-3 | 1174 | |||
| UPI000B4F7E70 | 1097 | ||||
| UPI000A306DC0 | 1094 | ||||
| UPI000A315465 | 1094 | ||||
| ankyrin-3 isoform X16 | 1087 | ||||
| +4 | |||||
| O70511-6 | UPI000661BED3 | 991 | |||
| UPI00076284F7 | 991 | ||||
| Ankyrin-3 | 978 | ||||
| Ankyrin-3 | 977 | ||||
| Uncharacterized protein | 900 | ||||
| +12 | |||||
| O70511-7 | Ankyrin-3 | 961 | |||
| UPI000A30874D | 838 | ||||
| Ankyrin-3 skin-specific splice variant | 838 | ||||
| Ankyrin 3, epithelial, isoform CRA_i | 838 | ||||
| Protein | Similar proteins | Species | Score | Length | |
|---|---|---|---|---|---|
| O70511 | AnkyrinG (Fragment) | 287 | |||
| UPI000B7B0D07 | 2728 | ||||
| UPI0005F4BA5B | 2727 | ||||
| UPI000945A1A3 | 2723 | ||||
| UPI000A326714 | 2626 | ||||
| +5 | |||||
| O70511-2 | Ankyrin-3 | 1985 | |||
| Ankyrin-3 | 1963 | ||||
| UPI000A318322 | 1726 | ||||
| UPI000A3105EA | 1726 | ||||
| Uncharacterized protein | 1889 | ||||
| +42 | |||||
| O70511-3 | Ankyrin-3 | 1985 | |||
| Ankyrin-3 | 1963 | ||||
| UPI000A318322 | 1726 | ||||
| UPI000A3105EA | 1726 | ||||
| Uncharacterized protein | 1889 | ||||
| +42 | |||||
| O70511-4 | Uncharacterized protein | 1171 | |||
| UPI00076024FC | 1175 | ||||
| Ankyrin-3 | 1174 | ||||
| Uncharacterized protein | 1058 | ||||
| UPI00074FE263 | 1178 | ||||
| +33 | |||||
| O70511-5 | Uncharacterized protein | 1171 | |||
| UPI00076024FC | 1175 | ||||
| Ankyrin-3 | 1174 | ||||
| Uncharacterized protein | 1058 | ||||
| UPI00074FE263 | 1178 | ||||
| +33 | |||||
| O70511-6 | UPI000760AF23 | 1103 | |||
| UPI000A1BF45F | 1102 | ||||
| UPI000652BFDA | 1096 | ||||
| UPI0005FB2BC9 | 1094 | ||||
| UPI000577844E | 1094 | ||||
| +123 | |||||
| O70511-7 | UPI000760AF23 | 1103 | |||
| UPI000A1BF45F | 1102 | ||||
| UPI000652BFDA | 1096 | ||||
| UPI0005FB2BC9 | 1094 | ||||
| UPI000577844E | 1094 | ||||
| +123 | |||||
<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi
Sequence databases
| Select the link destinations: EMBL nucleotide sequence database More...EMBLiGenBank nucleotide sequence database More...GenBankiDNA Data Bank of Japan; a nucleotide sequence database More...DDBJiLinks Updated | AF102552 mRNA Translation: AAC78143.1 AJ428573 mRNA Translation: CAD21705.1 AJ812019 mRNA Translation: CAH19219.1 AJ812021 mRNA Translation: CAH19221.1 AJ812022 mRNA Translation: CAH19222.1 AJ812023 mRNA Translation: CAH19223.1 AJ812024 mRNA Translation: CAH19224.1 |
NCBI Reference Sequences More...RefSeqi | NP_001029156.1, NM_001033984.1 [O70511-1] NP_113993.1, NM_031805.1 [O70511-2] |
UniGene gene-oriented nucleotide sequence clusters More...UniGenei | Rn.211093 Rn.212410 |
3D structure databases
SWISS-MODEL Repository - a database of annotated 3D protein structure models More...SMRi | O70511 |
Database of comparative protein structure models More...ModBasei | Search... |
MobiDB: a database of protein disorder and mobility annotations More...MobiDBi | Search... |
Protein-protein interaction databases
The Biological General Repository for Interaction Datasets (BioGrid) More...BioGridi | 262995, 3 interactors |
CORUM comprehensive resource of mammalian protein complexes More...CORUMi | O70511 |
Database of interacting proteins More...DIPi | DIP-60342N |
Protein interaction database and analysis system More...IntActi | O70511, 7 interactors |
STRING: functional protein association networks More...STRINGi | 10116.ENSRNOP00000043687 |
PTM databases
iPTMnet integrated resource for PTMs in systems biology context More...iPTMneti | O70511 |
Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat. More...PhosphoSitePlusi | O70511 |
SwissPalm database of S-palmitoylation events More...SwissPalmi | O70511 |
Proteomic databases
PaxDb, a database of protein abundance averages across all three domains of life More...PaxDbi | O70511 |
PRoteomics IDEntifications database More...PRIDEi | O70511 |
Protocols and materials databases
| Structural Biology Knowledgebase | Search... |
Genome annotation databases
Database of genes from NCBI RefSeq genomes More...GeneIDi | 361833 |
KEGG: Kyoto Encyclopedia of Genes and Genomes More...KEGGi | rno:361833 |
UCSC genome browser More...UCSCi | RGD:620157 rat |
Organism-specific databases
Comparative Toxicogenomics Database More...CTDi | 288 |
Rat genome database More...RGDi | 620157 Ank3 |
Phylogenomic databases
evolutionary genealogy of genes: Non-supervised Orthologous Groups More...eggNOGi | KOG4177 Eukaryota COG0666 LUCA |
The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms More...HOGENOMi | HOG000012873 |
The HOVERGEN Database of Homologous Vertebrate Genes More...HOVERGENi | HBG024337 |
KEGG Orthology (KO) More...KOi | K10380 |
Miscellaneous databases
Protein Ontology More...PROi | PR:O70511 |
Family and domain databases
Conserved Domains Database More...CDDi | cd00204 ANK, 7 hits cd08803 Death_ank3, 1 hit |
Gene3D Structural and Functional Annotation of Protein Families More...Gene3Di | 1.25.40.20, 3 hits |
Integrated resource of protein families, domains and functional sites More...InterProi | View protein in InterPro IPR037971 Ank3_Death IPR002110 Ankyrin_rpt IPR020683 Ankyrin_rpt-contain_dom IPR036770 Ankyrin_rpt-contain_sf IPR011029 DEATH-like_dom_sf IPR000488 Death_domain IPR000906 ZU5_dom |
Pfam protein domain database More...Pfami | View protein in Pfam PF00023 Ank, 2 hits PF12796 Ank_2, 6 hits PF13606 Ank_3, 1 hit PF00531 Death, 1 hit PF00791 ZU5, 1 hit |
Protein Motif fingerprint database; a protein domain database More...PRINTSi | PR01415 ANKYRIN |
Simple Modular Architecture Research Tool; a protein domain database More...SMARTi | View protein in SMART SM00248 ANK, 22 hits SM00005 DEATH, 1 hit SM00218 ZU5, 1 hit |
Superfamily database of structural and functional annotation More...SUPFAMi | SSF47986 SSF47986, 1 hit SSF48403 SSF48403, 3 hits |
PROSITE; a protein domain and family database More...PROSITEi | View protein in PROSITE PS50297 ANK_REP_REGION, 1 hit PS50088 ANK_REPEAT, 21 hits PS50017 DEATH_DOMAIN, 1 hit PS51145 ZU5, 2 hits |
ProtoNet; Automatic hierarchical classification of proteins More...ProtoNeti | Search... |
<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi
| <p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry namei | ANK3_RAT | |
| <p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>Accessioni | O70511Primary (citable) accession number: O70511 Secondary accession number(s): Q574D7 , Q574D8, Q574D9, Q574E0, Q574E2, Q8VDA0 | |
| <p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 9, 2014 |
| Last sequence update: | July 9, 2014 | |
| Last modified: | May 23, 2018 | |
| This is version 131 of the entry and version 3 of the sequence. See complete history. | ||
| <p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
| Annotation program | Chordata Protein Annotation Program | |
