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Protein

Carbonic anhydrase-related protein 11

Gene

Ca11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Does not have a catalytic activity.

GO - Molecular functioni

Names & Taxonomyi

Protein namesi
Recommended name:
Carbonic anhydrase-related protein 11
Alternative name(s):
CA-RP XI
Short name:
CA-XI
Short name:
CARP XI
Carbonic anhydrase-related protein 2
Short name:
CA-RP II
Short name:
CARP-2
Gene namesi
Name:Ca11
Synonyms:Car11, Carp2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1336193 Car11

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000000424624 – 328Carbonic anhydrase-related protein 11Add BLAST305

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi118N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PaxDbiO70354
PRIDEiO70354

PTM databases

iPTMnetiO70354
PhosphoSitePlusiO70354

Expressioni

Gene expression databases

BgeeiENSMUSG00000003273 Expressed in 196 organ(s), highest expression level in olfactory tubercle
CleanExiMM_CAR11
ExpressionAtlasiO70354 baseline and differential
GenevisibleiO70354 MM

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003360

Structurei

3D structure databases

ProteinModelPortaliO70354
SMRiO70354
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini33 – 303Alpha-carbonic anhydrasePROSITE-ProRule annotationAdd BLAST271

Sequence similaritiesi

Belongs to the alpha-carbonic anhydrase family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiKOG0382 Eukaryota
COG3338 LUCA
GeneTreeiENSGT00920000149072
HOGENOMiHOG000019899
HOVERGENiHBG097666
InParanoidiO70354
OMAiAVSWEEW
OrthoDBiEOG091G0T4J
PhylomeDBiO70354
TreeFamiTF352926

Family and domain databases

Gene3Di3.10.200.10, 1 hit
InterProiView protein in InterPro
IPR001148 CA_dom
IPR036398 CA_dom_sf
IPR023561 Carbonic_anhydrase_a-class
PANTHERiPTHR18952 PTHR18952, 1 hit
PfamiView protein in Pfam
PF00194 Carb_anhydrase, 1 hit
SMARTiView protein in SMART
SM01057 Carb_anhydrase, 1 hit
SUPFAMiSSF51069 SSF51069, 1 hit
PROSITEiView protein in PROSITE
PS51144 ALPHA_CA_2, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

O70354-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGGAARLSAP QALVLWAALG AAAHIGPAPD PEDWWSYKEN LQGNFVPGPP
60 70 80 90 100
FWGLVNAAWS LCAVGKRQSP VDVELKRVLY DPFLPPLRLS TGGEKLRGTL
110 120 130 140 150
YNTGRHVSFL PASRPVVNVS GGPLLYSHRL SELRLLFGAR DGAGSEHQIN
160 170 180 190 200
HEGFSAEVQL IHFNQELYGN LSAASRGPNG LAILSLFVNV AGSSNPFLSR
210 220 230 240 250
LLNRDTITRI SYKNDAYFLQ DLSLELLFPE SFGFITYQGS LSTPPCSETV
260 270 280 290 300
TWILIDRALN ITSLQMHSLR LLSQNPPSQI FQSLSGNGRP LQPLAHRALR
310 320
GNRDPRHPER RCRGPNYRLH VDGGPHGR
Length:328
Mass (Da):36,051
Last modified:May 9, 2003 - v2
Checksum:i483E9770CC4362FD
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1B0GRJ7A0A1B0GRJ7_MOUSE
Carbonic anhydrase 11
Car11
82Annotation score:
A0A1B0GT65A0A1B0GT65_MOUSE
Carbonic anhydrase 11
Car11
26Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB079601 mRNA Translation: BAC07262.1
BC019393 mRNA Translation: AAH19393.1
AF050105 mRNA Translation: AAD08801.1
CCDSiCCDS21259.1
RefSeqiNP_033930.1, NM_009800.4
UniGeneiMm.27736

Genome annotation databases

EnsembliENSMUST00000003360; ENSMUSP00000003360; ENSMUSG00000003273
GeneIDi12348
KEGGimmu:12348
UCSCiuc009gwr.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB079601 mRNA Translation: BAC07262.1
BC019393 mRNA Translation: AAH19393.1
AF050105 mRNA Translation: AAD08801.1
CCDSiCCDS21259.1
RefSeqiNP_033930.1, NM_009800.4
UniGeneiMm.27736

3D structure databases

ProteinModelPortaliO70354
SMRiO70354
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000003360

PTM databases

iPTMnetiO70354
PhosphoSitePlusiO70354

Proteomic databases

PaxDbiO70354
PRIDEiO70354

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000003360; ENSMUSP00000003360; ENSMUSG00000003273
GeneIDi12348
KEGGimmu:12348
UCSCiuc009gwr.1 mouse

Organism-specific databases

CTDi12348
MGIiMGI:1336193 Car11

Phylogenomic databases

eggNOGiKOG0382 Eukaryota
COG3338 LUCA
GeneTreeiENSGT00920000149072
HOGENOMiHOG000019899
HOVERGENiHBG097666
InParanoidiO70354
OMAiAVSWEEW
OrthoDBiEOG091G0T4J
PhylomeDBiO70354
TreeFamiTF352926

Miscellaneous databases

PROiPR:O70354
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000003273 Expressed in 196 organ(s), highest expression level in olfactory tubercle
CleanExiMM_CAR11
ExpressionAtlasiO70354 baseline and differential
GenevisibleiO70354 MM

Family and domain databases

Gene3Di3.10.200.10, 1 hit
InterProiView protein in InterPro
IPR001148 CA_dom
IPR036398 CA_dom_sf
IPR023561 Carbonic_anhydrase_a-class
PANTHERiPTHR18952 PTHR18952, 1 hit
PfamiView protein in Pfam
PF00194 Carb_anhydrase, 1 hit
SMARTiView protein in SMART
SM01057 Carb_anhydrase, 1 hit
SUPFAMiSSF51069 SSF51069, 1 hit
PROSITEiView protein in PROSITE
PS51144 ALPHA_CA_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCAH11_MOUSE
AccessioniPrimary (citable) accession number: O70354
Secondary accession number(s): Q8VEA9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: May 9, 2003
Last modified: September 12, 2018
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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