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Protein

Cell death activator CIDE-B

Gene

Cideb

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Activates apoptosis.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processApoptosis

Names & Taxonomyi

Protein namesi
Recommended name:
Cell death activator CIDE-B
Alternative name(s):
Cell death-inducing DFFA-like effector B
Gene namesi
Name:Cideb
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1270844 Cideb

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001447211 – 219Cell death activator CIDE-BAdd BLAST219

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei18PhosphothreonineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiO70303
PaxDbiO70303
PRIDEiO70303

PTM databases

iPTMnetiO70303
PhosphoSitePlusiO70303

Expressioni

Gene expression databases

BgeeiENSMUSG00000022219 Expressed in 124 organ(s), highest expression level in jejunum
GenevisibleiO70303 MM

Interactioni

Subunit structurei

Inhibited by DFFB. Interacts with DFFA and DFFB (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000001497

Structurei

3D structure databases

ProteinModelPortaliO70303
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini34 – 110CIDE-NPROSITE-ProRule annotationAdd BLAST77

Phylogenomic databases

eggNOGiENOG410IIBQ Eukaryota
ENOG4111N1Y LUCA
GeneTreeiENSGT00390000018596
HOGENOMiHOG000029211
HOVERGENiHBG050961
InParanoidiO70303
OMAiEGAEQWQ
OrthoDBiEOG091G0KVY
PhylomeDBiO70303
TreeFamiTF334321

Family and domain databases

InterProiView protein in InterPro
IPR003508 CIDE-N_dom
PfamiView protein in Pfam
PF02017 CIDE-N, 1 hit
SMARTiView protein in SMART
SM00266 CAD, 1 hit
PROSITEiView protein in PROSITE
PS51135 CIDE_N, 1 hit

Sequencei

Sequence statusi: Complete.

O70303-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEYLSAFNPN GLLRSVSTVS SELSRRVWNS APPPQRPFRV CDHKRTVRKG
60 70 80 90 100
LTAASLQELL DKVLETLLLR GVLTLVLEED GTAVDSEDFF QLLEDDTCLM
110 120 130 140 150
VLEQGQSWSP KSGMLSYGLG REKPKHSKDI ARITFDVYKQ NPRDLFGSLN
160 170 180 190 200
VKATFYGLYS MSCDFQGVGP KRVLRELLRW TSSLLQGLGH MLLGISSTLR
210
HVVEGADRWQ WHGQRHLHS
Length:219
Mass (Da):24,800
Last modified:March 27, 2002 - v2
Checksum:i8915FB3CC5FE7721
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti180W → G in AAC34986 (PubMed:9564035).Curated1
Sequence conflicti184L → Q in AAC34986 (PubMed:9564035).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF041377 mRNA Translation: AAC34986.1
BC012664 mRNA Translation: AAH12664.1
BC046340 mRNA Translation: AAH46340.1
CCDSiCCDS27127.1
RefSeqiNP_034024.2, NM_009894.3
UniGeneiMm.466766

Genome annotation databases

EnsembliENSMUST00000001497; ENSMUSP00000001497; ENSMUSG00000022219
GeneIDi12684
KEGGimmu:12684
UCSCiuc007uap.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF041377 mRNA Translation: AAC34986.1
BC012664 mRNA Translation: AAH12664.1
BC046340 mRNA Translation: AAH46340.1
CCDSiCCDS27127.1
RefSeqiNP_034024.2, NM_009894.3
UniGeneiMm.466766

3D structure databases

ProteinModelPortaliO70303
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000001497

PTM databases

iPTMnetiO70303
PhosphoSitePlusiO70303

Proteomic databases

MaxQBiO70303
PaxDbiO70303
PRIDEiO70303

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000001497; ENSMUSP00000001497; ENSMUSG00000022219
GeneIDi12684
KEGGimmu:12684
UCSCiuc007uap.2 mouse

Organism-specific databases

CTDi27141
MGIiMGI:1270844 Cideb

Phylogenomic databases

eggNOGiENOG410IIBQ Eukaryota
ENOG4111N1Y LUCA
GeneTreeiENSGT00390000018596
HOGENOMiHOG000029211
HOVERGENiHBG050961
InParanoidiO70303
OMAiEGAEQWQ
OrthoDBiEOG091G0KVY
PhylomeDBiO70303
TreeFamiTF334321

Miscellaneous databases

ChiTaRSiCideb mouse
PROiPR:O70303
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000022219 Expressed in 124 organ(s), highest expression level in jejunum
GenevisibleiO70303 MM

Family and domain databases

InterProiView protein in InterPro
IPR003508 CIDE-N_dom
PfamiView protein in Pfam
PF02017 CIDE-N, 1 hit
SMARTiView protein in SMART
SM00266 CAD, 1 hit
PROSITEiView protein in PROSITE
PS51135 CIDE_N, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiCIDEB_MOUSE
AccessioniPrimary (citable) accession number: O70303
Secondary accession number(s): Q91X39
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: March 27, 2002
Last modified: November 7, 2018
This is version 126 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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