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UniProtKB - O70230 (ZN143_MOUSE)

Entry version 152 (23 Feb 2022)
Sequence version 2 (05 May 2009)
Previous versions | rss
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Protein

Zinc finger protein 143

Gene

Znf143

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional activator. Activates the gene for selenocysteine tRNA (tRNAsec). Binds to the SPH motif of small nuclear RNA (snRNA) gene promoters. Participates in efficient U6 RNA polymerase III transcription via its interaction with CHD8 (By similarity).

By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri237 – 261C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri267 – 291C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri297 – 321C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri327 – 351C2H2-type 4PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri357 – 381C2H2-type 5PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri387 – 411C2H2-type 6PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri417 – 440C2H2-type 7PROSITE-ProRule annotationAdd BLAST24

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, DNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Zinc finger protein 143
Short name:
Zfp-143
Alternative name(s):
Selenocysteine tRNA gene transcription-activating factor
Short name:
mStaf
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Znf143
Synonyms:Staf, Zfp143
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:1277969, Zfp143

Eukaryotic Pathogen, Vector and Host Database Resources

More...VEuPathDBi		HostDB:ENSMUSG00000061079

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002480711 – 638Zinc finger protein 143Add BLAST638

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei1N-acetylmethionineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes <strong>covalent linkages</strong> of various types formed <strong>between two proteins (interchain cross-links)</strong> or <strong>between two parts of the same protein (intrachain cross-links)</strong>, except the disulfide bonds that are annotated in the <a href="http://www.uniprot.org/manual/disulfid">'Disulfide bond'</a> subsection.<p><a href='/help/crosslnk' target='_top'>More...</a></p>Cross-linki213Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei352PhosphothreonineBy similarity1
Cross-linki406Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O70230

MaxQB - The MaxQuant DataBase

More...MaxQBi		O70230

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O70230

PeptideAtlas

More...PeptideAtlasi		O70230

PRoteomics IDEntifications database

More...PRIDEi		O70230

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		274999 [O70230-1]
275000 [O70230-2]
275001 [O70230-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O70230

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O70230

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000061079, Expressed in embryo and 296 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O70230, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with CHD8.

By similarity

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		203516, 7 interactors

Protein interaction database and analysis system

More...IntActi		O70230, 4 interactors

Molecular INTeraction database

More...MINTi		O70230

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000081778

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O70230, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O70230

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the GLI C2H2-type zinc-finger protein family.Curated

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri237 – 261C2H2-type 1PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri267 – 291C2H2-type 2PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri297 – 321C2H2-type 3PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri327 – 351C2H2-type 4PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri357 – 381C2H2-type 5PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri387 – 411C2H2-type 6PROSITE-ProRule annotationAdd BLAST25
Zinc fingeri417 – 440C2H2-type 7PROSITE-ProRule annotationAdd BLAST24

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG1721, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000157584

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_027168_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O70230

Identification of Orthologs from Complete Genome Data

More...OMAi		SEMGHQP

Database of Orthologous Groups

More...OrthoDBi		1318335at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O70230

TreeFam database of animal gene trees

More...TreeFami		TF333498

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00096, zf-C2H2, 5 hits

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00355, ZnF_C2H2, 7 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF57667, SSF57667, 3 hits

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 7 hits
PS50157, ZINC_FINGER_C2H2_2, 7 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: O70230-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <p><strong>What is the canonical sequence?</strong><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MLLAQINRDS QGMTEFPGGG MEAQHVTLCL TEAVTVADGD NLENMEGVSL 
        60         70         80         90        100
QAVTLADGST AYIQHNSKDG RLIDGQVIQL EDGSAAYVQH VPIPKSTGDS 
       110        120        130        140        150
LRLEDGQAVQ LEDGTTAFIH HTSKDSYDQS SLQAVQLEDG TTAYIHHAVQ 
       160        170        180        190        200
VPQSDTILAI QADGTVAGLH TGDATIDPDT ISALEQYAAK VSIDGSDGVT 
       210        220        230        240        250
STGMIGENEQ EKKMQIVLQG HATRVTPKSQ QSGEKAFRCK YDGCGKLYTT 
       260        270        280        290        300
AHHLKVHERS HTGDRPYQCE HSGCGKAFAT GYGLKSHFRT HTGEKPYRCS 
       310        320        330        340        350
EDNCTKSFKT SGDLQKHIRT HTGERPFKCP IEGCGRSFTT SNIRKVHIRT 
       360        370        380        390        400
HTGERPYYCT EPGCGRAFAS ATNYKNHVRI HTGEKPYVCT VPGCDKRFTE 
       410        420        430        440        450
YSSLYKHHVV HTHSKPYNCN HCGKTYKQIS TLAMHKRTAH NDTEPIEEEQ 
       460        470        480        490        500
EAFFEPPPGQ GDDVLKGSQI TYVTGVDGED IVSTQVATVT QSGLSQQVTL 
       510        520        530        540        550
ISQDGTQHVN ISQADMQAIG NTITMVTQDG TPITVPTHDA VISSAGTHSV 
       560        570        580        590        600
AMVTAEGTEG QQVAIVAQDL AAFHTASSEM GHQQHSHHLV TTETRPLTLV 
       610        620        630 
ATSNGTQIAV QLGEQPSLEE AIRIASRIQQ GETPGLDD
Length:638
Mass (Da):69,040
Last modified:May 5, 2009 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i9BDA0B6C0EBC0634
GO
Isoform 2 (identifier: O70230-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     97-98: TG → R

Show »
Length:637
Mass (Da):69,038
Checksum:iAF55892CDA7BD887
GO
Isoform 3 (identifier: O70230-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     97-125: TGDSLRLEDGQAVQLEDGTTAFIHHTSKD → N

Show »
Length:610
Mass (Da):66,030
Checksum:i3E608E4FA31A3CDE
GO

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC16899 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAH37658 differs from that shown. Reason: Erroneous initiation.Curated
The sequence BAC25726 differs from that shown. Reason: Frameshift.Curated
The sequence BAC26281 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAC17144 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti190K → T in BAC25726 (PubMed:16141072).Curated1
Sequence conflicti250T → K in BAC25726 (PubMed:16141072).Curated1
Sequence conflicti261H → D in BAC25726 (PubMed:16141072).Curated1
Sequence conflicti342N → T in BAC25726 (PubMed:16141072).Curated1
Sequence conflicti508H → N in BAC25726 (PubMed:16141072).Curated1
Sequence conflicti528Q → K in BAC25726 (PubMed:16141072).Curated1
Sequence conflicti618L → V in BAC25726 (PubMed:16141072).Curated1
Sequence conflicti634P → A in BAC25726 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_03697997 – 125TGDSL…HTSKD → N in isoform 3. 1 PublicationAdd BLAST29
Alternative sequenceiVSP_03698097 – 98TG → R in isoform 2. 1 Publication2

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF011758 mRNA Translation: AAC16899.1 Different initiation.
AJ278435 Genomic DNA Translation: CAC17144.1 Different initiation.
AK028056 mRNA Translation: BAC25726.1 Frameshift.
AK029078 mRNA Translation: BAC26281.1 Different initiation.
AK029926 mRNA Translation: BAC26682.1
BC037658 mRNA Translation: AAH37658.1 Different initiation.

The Consensus CDS (CCDS) project

More...CCDSi		CCDS57580.1 [O70230-2]
CCDS90307.1 [O70230-1]

NCBI Reference Sequences

More...RefSeqi		NP_033307.2, NM_009281.3 [O70230-2]
XP_006507595.1, XM_006507532.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000084727; ENSMUSP00000081778; ENSMUSG00000061079 [O70230-1]
ENSMUST00000169638; ENSMUSP00000126015; ENSMUSG00000061079 [O70230-3]
ENSMUST00000209505; ENSMUSP00000147673; ENSMUSG00000061079 [O70230-2]
ENSMUST00000211798; ENSMUSP00000148235; ENSMUSG00000061079 [O70230-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		20841

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:20841

UCSC genome browser

More...UCSCi		uc009jew.1, mouse [O70230-2]
uc009jex.1, mouse [O70230-1]
uc012fse.1, mouse [O70230-3]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF011758 mRNA Translation: AAC16899.1 Different initiation.
AJ278435 Genomic DNA Translation: CAC17144.1 Different initiation.
AK028056 mRNA Translation: BAC25726.1 Frameshift.
AK029078 mRNA Translation: BAC26281.1 Different initiation.
AK029926 mRNA Translation: BAC26682.1
BC037658 mRNA Translation: AAH37658.1 Different initiation.
CCDSiCCDS57580.1 [O70230-2]
CCDS90307.1 [O70230-1]
RefSeqiNP_033307.2, NM_009281.3 [O70230-2]
XP_006507595.1, XM_006507532.2

3D structure databases

SMRiO70230
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi203516, 7 interactors
IntActiO70230, 4 interactors
MINTiO70230
STRINGi10090.ENSMUSP00000081778

PTM databases

iPTMnetiO70230
PhosphoSitePlusiO70230

Proteomic databases

EPDiO70230
MaxQBiO70230
PaxDbiO70230
PeptideAtlasiO70230
PRIDEiO70230
ProteomicsDBi274999 [O70230-1]
275000 [O70230-2]
275001 [O70230-3]

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		927, 86 antibodies from 24 providers

The DNASU plasmid repository

More...DNASUi		20841

Genome annotation databases

EnsembliENSMUST00000084727; ENSMUSP00000081778; ENSMUSG00000061079 [O70230-1]
ENSMUST00000169638; ENSMUSP00000126015; ENSMUSG00000061079 [O70230-3]
ENSMUST00000209505; ENSMUSP00000147673; ENSMUSG00000061079 [O70230-2]
ENSMUST00000211798; ENSMUSP00000148235; ENSMUSG00000061079 [O70230-2]
GeneIDi20841
KEGGimmu:20841
UCSCiuc009jew.1, mouse [O70230-2]
uc009jex.1, mouse [O70230-1]
uc012fse.1, mouse [O70230-3]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		20841
MGIiMGI:1277969, Zfp143
VEuPathDBiHostDB:ENSMUSG00000061079

Phylogenomic databases

eggNOGiKOG1721, Eukaryota
GeneTreeiENSGT00940000157584
HOGENOMiCLU_027168_0_0_1
InParanoidiO70230
OMAiSEMGHQP
OrthoDBi1318335at2759
PhylomeDBiO70230
TreeFamiTF333498

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		20841, 2 hits in 64 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Zfp143, mouse

Protein Ontology

More...PROi		PR:O70230
RNActiO70230, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000061079, Expressed in embryo and 296 other tissues
GenevisibleiO70230, MM

Family and domain databases

InterProiView protein in InterPro
IPR036236, Znf_C2H2_sf
IPR013087, Znf_C2H2_type
PfamiView protein in Pfam
PF00096, zf-C2H2, 5 hits
SMARTiView protein in SMART
SM00355, ZnF_C2H2, 7 hits
SUPFAMiSSF57667, SSF57667, 3 hits
PROSITEiView protein in PROSITE
PS00028, ZINC_FINGER_C2H2_1, 7 hits
PS50157, ZINC_FINGER_C2H2_2, 7 hits

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiZN143_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O70230
Secondary accession number(s): Q8BGB0, Q8CEI6, Q8CI27
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: May 5, 2009
Last modified: February 23, 2022
This is version 152 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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