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Protein
Submitted name:

Penicillin-binding protein 1B

Gene

pbp1b

Organism
Streptococcus pneumoniae
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseSAAS annotation

Protein family/group databases

CAZyiGT51 Glycosyltransferase Family 51

Names & Taxonomyi

Protein namesi
Submitted name:
Penicillin-binding protein 1BImported
Submitted name:
TransglycosylaseImported
Gene namesi
Name:pbp1bImported
Synonyms:pbp1BImported
ORF Names:AWW74_04855Imported, ERS367337_00380Imported
OrganismiStreptococcus pneumoniaeImported
Taxonomic identifieri1313 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus
Proteomesi
  • UP000071227 Componenti: Unassembled WGS sequence
  • UP000070671 Componenti: Unassembled WGS sequence

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei60 – 84HelicalSequence analysisAdd BLAST25

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Chemistry databases

DrugBankiDB08401 (2E)-2-({(2S)-2-CARBOXY-2-[(PHENOXYACETYL)AMINO]ETHOXY}IMINO)PENTANEDIOIC ACID

Structurei

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini113 – 302TransglyInterPro annotationAdd BLAST190
Domaini425 – 657TranspeptidaseInterPro annotationAdd BLAST233

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZ4 Bacteria
COG0744 LUCA

Family and domain databases

Gene3Di1.10.3810.10, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR001264 Glyco_trans_51
IPR023346 Lysozyme-like_dom_sf
IPR036950 PBP_transglycosylase
IPR001460 PCN-bd_Tpept
PfamiView protein in Pfam
PF00912 Transgly, 1 hit
PF00905 Transpeptidase, 1 hit
SUPFAMiSSF53955 SSF53955, 1 hit
SSF56601 SSF56601, 2 hits

Sequencei

Sequence statusi: Complete.

O70038-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MQNQLNELKR KMLEFFQQKQ KNKKSARPGK KGSSTKKSKT LDKSAIFPAI
60 70 80 90 100
LLSIKALFNL LFVLGFLGGM LGAGIALGYG VALFDKVRVP QTEELVNQVK
110 120 130 140 150
DISSISEITY SDGTVIASIE SDLLRTSISS EQISENLKKA IIATEDEHFK
160 170 180 190 200
EHKGVVPKAV IRATLGKFVG LGSSSGGSTL TQQLIKQQVV GDAPTLARKA
210 220 230 240 250
AEIVDALALE RAMNKDEILT TYLNVAPFGR NNKGQNIAGA RQAAEGIFGV
260 270 280 290 300
DASQLTVPQA AFLAGLPQSP ITYSPYENTG ELKSDEDLEI GLRRAKAVLY
310 320 330 340 350
SMYRTGALSK DEYSQYKDYD LKQDFLPSGT VTGISRDYLY FTTLAEAQER
360 370 380 390 400
MYDYLAQRDN VSAKELKNEA TQKFYRDLAA KEIENGGYKI TTTIDQKIHS
410 420 430 440 450
AMQSAVADYG YLLDDGTGRV EVGNVLMDNQ TGAILGFVGG RNYQENQNNH
460 470 480 490 500
AFDTKRSPAS TTKPLLAYGI AIDQGLMGSE TILSNYPTNF ANGNPIMYAN
510 520 530 540 550
SKGTGMMTLG EALNYSWNIP AYWTYRMLRE NGVDVKGYME KMGYEIPEYG
560 570 580 590 600
IESLPMGGGI EVTVAQHTNG YQTLANNGVY HQKHVISKIE AADGRVVYEY
610 620 630 640 650
QDKPVQVYSK ATATIMQGLL REVLSSRVTT TFKSNLTSLN PTLANADWIG
660 670 680 690 700
KTGTTNQDEN MWLMLSTPRL TLGGWIGHDD NHSLSRRAGY SNNSNYMAHL
710 720 730 740 750
VNAIQQASPS IWGNERFALD PSVVKSEVLK STGQKPGKVS VEGKEVEVTG
760 770 780 790 800
STVTSYWANK SGAPATSYRF AIGGSDADYQ NAWSSIVGSL PTPSSSSSSS
810 820
SSSSDSSNSS TTRPSSSRAR R
Length:821
Mass (Da):89,481
Last modified:August 1, 1998 - v1
Checksum:iDA94560B4B8BD3AB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF101781 Genomic DNA Translation: AAF04736.1
AB119817 Genomic DNA Translation: BAD00805.1
AB119819 Genomic DNA Translation: BAD00807.1
AJ002291 Genomic DNA Translation: CAA05302.1
FEBA01000002 Genomic DNA Translation: CWE37508.1
LRSN01000205 Genomic DNA Translation: KWX81879.1
PIRiB99110
RefSeqiWP_001180963.1, NZ_MVBL01000012.1

Genome annotation databases

EnsemblBacteriaiCFP93634; CFP93634; ERS013931_01581
CJK40808; CJK40808; ERS022016_01476
CJY52478; CJY52478; ERS022329_01607
CMW84015; CMW84015; ERS077238_00877
CNA64534; CNA64534; ERS077235_01093
CNA85713; CNA85713; ERS077244_00850
CWE37508; CWE37508; ERS367337_00380
KWX81879; KWX81879; AWW74_04855

Similar proteinsi

Entry informationi

Entry nameiO70038_STREE
AccessioniPrimary (citable) accession number: O70038
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: July 18, 2018
This is version 124 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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