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Entry version 139 (25 May 2022)
Sequence version 1 (01 Aug 1998)
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Protein
Submitted name:

Hydroxamate-type ferrisiderophore receptor

Gene

piuA

Organism
Pseudomonas aeruginosa
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptorImportedARBA annotation

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.B.14.1.31, the outer membrane receptor (omr) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Hydroxamate-type ferrisiderophore receptorImported
Submitted name:
Iron transport protein FiuImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:piuAImported
Synonyms:fiuImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPseudomonas aeruginosaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri287 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Organism-specific databases

Pseudomonas genome database

More...
PseudoCAPi
PA4514

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell outer membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 35Sequence analysisAdd BLAST35
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_501194514436 – 753Sequence analysisAdd BLAST718

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini81 – 178PlugInterPro annotationAdd BLAST98
Domaini257 – 751TonB_dep_RecInterPro annotationAdd BLAST495

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the TonB-dependent receptor family.UniRule annotationARBA annotation

Keywords - Domaini

SignalSequence analysis, TonB boxUniRule annotationARBA annotation

Phylogenomic databases

Database of Orthologous Groups

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OrthoDBi
169533at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.170.130.10, 1 hit
2.40.170.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030148, Fiu
IPR012910, Plug_dom
IPR037066, Plug_dom_sf
IPR039423, TonB-dep_rcpt
IPR000531, TonB-dep_rcpt_b-brl
IPR036942, TonB_rcpt_b-brl_sf
IPR010105, TonB_sidphr_rcpt

The PANTHER Classification System

More...
PANTHERi
PTHR32552, PTHR32552, 1 hit
PTHR32552:SF68, PTHR32552:SF68, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07715, Plug, 1 hit
PF00593, TonB_dep_Rec, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01783, TonB-siderophor, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O68590-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRQSTDTAV SSQRLLASAI GVAITAIAAP QAAQADEAGQ KKTDKDRVLS
60 70 80 90 100
LDAATIVGEQ QDETTYNVDR SASKKYTAPL LDTPKTVTVI PQQVIKDTGA
110 120 130 140 150
LTLADALRTT PGITFGAGEG GNPAGDRPFI RGFNAESDTF LDGMRDVASQ
160 170 180 190 200
TREVFNVEQI EVSKGPGSAY TGAGSTGGSL NLISKTAKQD NFTDAGFTWG
210 220 230 240 250
SDQTRRTTLD VNRMIGDNAA FRLNLMKHDA HVAGRDEVSV SRWGVAPTVT
260 270 280 290 300
FGFDTPTRAT LSYYHLSTDD MPDYGLPLTN VNRSKANPSK PASVDRDNFY
310 320 330 340 350
GLKDRDYRKS TTDSGTFRIE HDLNDNLTLS NSTRLVRTTL DYIVSNPDDS
360 370 380 390 400
RGNVANGYVY RSAKSRNSTS KGWVNQTDLK ANFETGFIKH TLVTGLEFSY
410 420 430 440 450
EDVHNRPYAI TSGGGAGNTC NARLLASGDC TSLNRPTPGD NWTGSITDGL
460 470 480 490 500
AYTDTDTKTS AAYVFDTLKL SEQWELNLGL RYDDFDTKSS GYQTAGRNGP
510 520 530 540 550
AGYFKRENNS HFWNYQTGLV YKPAPNGSIY LAWSTSSNPT GETGGEGQAD
560 570 580 590 600
ISVGNNGLDP ERNRNLELGT KWAFFDDALS LNAALFRTDK TNARVASPDV
610 620 630 640 650
STLQVLDGEQ RVQGVELGFN GKLTEKWKVF GGYTYLDSEI RKSTVKSDEG
660 670 680 690 700
NKMPQTAQNN FTLWTTYDLL QNFTIGGGTT YVDKQYGNTA NSTYIPSYWR
710 720 730 740 750
YDAMASYKVS KNVDLQLNVQ NLTDKRYFDQ VYSTHMAHVA PGRTALLGVN

FHF
Length:753
Mass (Da):82,337
Last modified:August 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4DD5430DC9D6514B
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF051690 Genomic DNA Translation: AAC06215.1
AF276976 Genomic DNA Translation: AAF87743.1

Protein sequence database of the Protein Information Resource

More...
PIRi
D83081

NCBI Reference Sequences

More...
RefSeqi
NP_253204.1, NC_002516.2
WP_003112850.1, NZ_WUDO01000024.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
881112

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pae:PA4514

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|287.2000.peg.4202

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF051690 Genomic DNA Translation: AAC06215.1
AF276976 Genomic DNA Translation: AAF87743.1
PIRiD83081
RefSeqiNP_253204.1, NC_002516.2
WP_003112850.1, NZ_WUDO01000024.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

TCDBi1.B.14.1.31, the outer membrane receptor (omr) family

Genome annotation databases

GeneIDi881112
KEGGipae:PA4514
PATRICifig|287.2000.peg.4202

Organism-specific databases

PseudoCAPiPA4514

Phylogenomic databases

OrthoDBi169533at2

Family and domain databases

Gene3Di2.170.130.10, 1 hit
2.40.170.20, 1 hit
InterProiView protein in InterPro
IPR030148, Fiu
IPR012910, Plug_dom
IPR037066, Plug_dom_sf
IPR039423, TonB-dep_rcpt
IPR000531, TonB-dep_rcpt_b-brl
IPR036942, TonB_rcpt_b-brl_sf
IPR010105, TonB_sidphr_rcpt
PANTHERiPTHR32552, PTHR32552, 1 hit
PTHR32552:SF68, PTHR32552:SF68, 1 hit
PfamiView protein in Pfam
PF07715, Plug, 1 hit
PF00593, TonB_dep_Rec, 1 hit
TIGRFAMsiTIGR01783, TonB-siderophor, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO68590_PSEAI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O68590
Secondary accession number(s): Q7DC69
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: May 25, 2022
This is version 139 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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