Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 112 (16 Jan 2019)
Sequence version 1 (01 Aug 1998)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein

Catalase

Gene

katA

Organism
Aliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Could protect cells in nodules which have a high potential to produce hydrogen peroxide because of the strong reducing conditions required for nitrogen fixation and the action of several proteins.

Miscellaneous

Either KatA or KatC is absolutely required for the protection of the nitrogen fixation process.

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

heme

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei53PROSITE-ProRule annotation1
Active sitei126PROSITE-ProRule annotation1
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi336Iron (heme axial ligand)By similarity1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionOxidoreductase, Peroxidase
Biological processHydrogen peroxide
LigandHeme, Iron, Metal-binding

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
VFIS312309:G1G40-2744-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Catalase (EC:1.11.1.6)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:katA
Ordered Locus Names:VF_A0009
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiAliivibrio fischeri (strain ATCC 700601 / ES114) (Vibrio fischeri)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri312309 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaVibrionalesVibrionaceaeAliivibrio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000537 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome II

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Periplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000850121 – 482CatalaseAdd BLAST482

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
O68146

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

By hydrogen peroxide.

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
312309.VF_A0009

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O68146

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O68146

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the catalase family.Curated

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG4105CH6 Bacteria
COG0753 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000087852

KEGG Orthology (KO)

More...
KOi
K03781

Identification of Orthologs from Complete Genome Data

More...
OMAi
HADFGRM

Database of Orthologous Groups

More...
OrthoDBi
1584770at2

Family and domain databases

Conserved Domains Database

More...
CDDi
cd08156 catalase_clade_3, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.40.180.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018028 Catalase
IPR040333 Catalase_3
IPR024708 Catalase_AS
IPR024711 Catalase_clade1/3
IPR011614 Catalase_core
IPR037060 Catalase_core_sf
IPR002226 Catalase_haem_BS
IPR010582 Catalase_immune_responsive
IPR020835 Catalase_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11465 PTHR11465, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00199 Catalase, 1 hit
PF06628 Catalase-rel, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF038928 Catalase_clade1-3, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00067 CATALASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01060 Catalase, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56634 SSF56634, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00437 CATALASE_1, 1 hit
PS00438 CATALASE_2, 1 hit
PS51402 CATALASE_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O68146-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSKKLTTAAG CPVAHNQNVQ TAGKRGPQLL QDVWFLEKLA HFDREVIPER
60 70 80 90 100
RMHAKGSGAY GTFTVTHDIT KYTKAKLFSE IGKQTELFAR FTTVAGERGA
110 120 130 140 150
ADAERDIRGF ALKFYTEEGN WDLVGNNTPV FFLRDPLKFP DLNHAVKRDP
160 170 180 190 200
RTNMRSAKNN WDFWTSLPEA LHQVTIVMSD RGIPATYRHM HGFGSHTFSF
210 220 230 240 250
INSDNERFWV KFHFKSQQGI KNLSDAEAAQ VIGQDRESHQ RDLLESIDNQ
260 270 280 290 300
DFPKWTLKVQ IMPEADAATV PYNPFDLTKV WPHKDYPLIE VGEFELNRNP
310 320 330 340 350
QNFFAEVEQS AFNPANVVPG ISFSPDKMLQ GRLFAYGDAQ RYRLGVNHQH
360 370 380 390 400
IPVNAPRCPV HSYHRDGAMR VDGNFGSTLG YEPNNEGQWA EQPDFAEPAL
410 420 430 440 450
NLDGAAAHWD HREDEDYFSQ PGDLFRLMTA EQQAILFDNT ARNLNGVPKE
460 470 480
IQLRHLRHCY KADPAYGEGI GKLLDIDVSE FN
Length:482
Mass (Da):54,864
Last modified:August 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3808F0DBDE4DCC32
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF011784 Genomic DNA Translation: AAC38344.1
CP000021 Genomic DNA Translation: AAW87079.1

NCBI Reference Sequences

More...
RefSeqi
WP_011262914.1, NC_006841.2
YP_205967.1, NC_006841.2

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAW87079; AAW87079; VF_A0009

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
3280053

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
vfi:VF_A0009

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|312309.11.peg.2611

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF011784 Genomic DNA Translation: AAC38344.1
CP000021 Genomic DNA Translation: AAW87079.1
RefSeqiWP_011262914.1, NC_006841.2
YP_205967.1, NC_006841.2

3D structure databases

ProteinModelPortaliO68146
SMRiO68146
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi312309.VF_A0009

Proteomic databases

PRIDEiO68146

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAW87079; AAW87079; VF_A0009
GeneIDi3280053
KEGGivfi:VF_A0009
PATRICifig|312309.11.peg.2611

Phylogenomic databases

eggNOGiENOG4105CH6 Bacteria
COG0753 LUCA
HOGENOMiHOG000087852
KOiK03781
OMAiHADFGRM
OrthoDBi1584770at2

Enzyme and pathway databases

BioCyciVFIS312309:G1G40-2744-MONOMER

Family and domain databases

CDDicd08156 catalase_clade_3, 1 hit
Gene3Di2.40.180.10, 1 hit
InterProiView protein in InterPro
IPR018028 Catalase
IPR040333 Catalase_3
IPR024708 Catalase_AS
IPR024711 Catalase_clade1/3
IPR011614 Catalase_core
IPR037060 Catalase_core_sf
IPR002226 Catalase_haem_BS
IPR010582 Catalase_immune_responsive
IPR020835 Catalase_sf
PANTHERiPTHR11465 PTHR11465, 1 hit
PfamiView protein in Pfam
PF00199 Catalase, 1 hit
PF06628 Catalase-rel, 1 hit
PIRSFiPIRSF038928 Catalase_clade1-3, 1 hit
PRINTSiPR00067 CATALASE
SMARTiView protein in SMART
SM01060 Catalase, 1 hit
SUPFAMiSSF56634 SSF56634, 1 hit
PROSITEiView protein in PROSITE
PS00437 CATALASE_1, 1 hit
PS00438 CATALASE_2, 1 hit
PS51402 CATALASE_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCATA_ALIF1
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O68146
Secondary accession number(s): Q5E1L7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: January 16, 2019
This is version 112 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again