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Protein

DNA polymerase III subunit epsilon-like protein

Gene

dnaQ

Organism
Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease (By similarity).By similarity

Caution

There might be a sequencing error that fuses together two ORFs.Curated

Catalytic activityi

Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-directed DNA polymerase, Nucleotidyltransferase, Transferase
Biological processDNA replication

Enzyme and pathway databases

BioCyciRCAP272942:G1GUE-2120-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA polymerase III subunit epsilon-like protein (EC:2.7.7.7)
Gene namesi
Name:dnaQ
Ordered Locus Names:RCAP_rcc02121
OrganismiRhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
Taxonomic identifieri272942 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhodobacteralesRhodobacteraceaeRhodobacter
Proteomesi
  • UP000002361 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001054911 – 704DNA polymerase III subunit epsilon-like proteinAdd BLAST704

Interactioni

Subunit structurei

DNA polymerase III contains a core (composed of alpha, epsilon and theta chains) that associates with a tau subunit. This core dimerizes to form the POLIII' complex. PolIII' associates with the gamma complex (composed of gamma, delta, delta', psi and chi chains) and with the beta chain to form the complete DNA polymerase III complex (By similarity).By similarity

Protein-protein interaction databases

STRINGi272942.RCAP_rcc02121

Structurei

3D structure databases

ProteinModelPortaliO68045
SMRiO68045
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini139 – 192PASPROSITE-ProRule annotationAdd BLAST54

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni511 – 704DNA-polymerase III epsilon chain-likeAdd BLAST194

Sequence similaritiesi

In the C-terminal section; belongs to the DNA polymerase III epsilon chain family.Curated

Phylogenomic databases

eggNOGiENOG4108IRC Bacteria
COG2176 LUCA
HOGENOMiHOG000146765
KOiK02342
OMAiPEYYDFD
OrthoDBiPOG091H01BK

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR006054 DnaQ
IPR013520 Exonuclease_RNaseT/DNA_pol3
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF00929 RNase_T, 1 hit
SMARTiView protein in SMART
SM00479 EXOIII, 1 hit
SUPFAMiSSF53098 SSF53098, 1 hit
SSF55785 SSF55785, 1 hit
TIGRFAMsiTIGR00573 dnaq, 1 hit
PROSITEiView protein in PROSITE
PS50112 PAS, 1 hit

Sequencei

Sequence statusi: Complete.

O68045-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLARLSLRL RIFLFFAALA MGNLAALVAG LVFGFHKLAR PEALSGFVIG
60 70 80 90 100
GTVAGLVILG LIGVVWALFD ANLARPIERL AGSIRARTQT AVDSALDESA
110 120 130 140 150
GRYLGDLAPA AAAIAQHLNE TRSALTEAVQ RETTRLAREK DRLETLLSDV
160 170 180 190 200
PVGVLLCTAD HALVFYNGQA VDLLGGAHAP GLDRRVFDYL HPAPIRHAHA
210 220 230 240 250
RLLATADPDA ASDLLCATVA DGRTLAARMR LISEGEDHQV RRLAGYVLTL
260 270 280 290 300
RDVSADLRAH AGREALMDEL FDRIRRPAAA LQSLMGVLIA EDGPADPQAR
310 320 330 340 350
AQLREAARAE AGHLAQAIHS LHDRHEAMRA DWWPLAMIRA SDFGAAVQAR
360 370 380 390 400
VAAEGAGDLL PVTAALLLRL EGFEMVALIA HLVRRLGPGR AEKRLEVLED
410 420 430 440 450
GAGALIALEW RGAAVAIADL ELWLSEPLDV GQAEVTGRRV LSVHATDLWP
460 470 480 490 500
ERLHEGRHRL CLPLREARRI GPDPHPVPRP VPRQVVYDFD LLGRGGESAL
510 520 530 540 550
AETPLDKLTF VVFDTETTGL FPTGGDEIVQ IAAVRIVNGR RVAGEVFDTL
560 570 580 590 600
VNPGRPIPAA STAVHGITEA MVATAPAIAE VGRRFHKFAE GAVLVAHNAP
610 620 630 640 650
FDLEFLRRKE LLIGKNFDNP VLDTVLLSAV VFGAAEGHSL DALTHRLGIT
660 670 680 690 700
IPEEARHTAL GDTVATAEAF LRLLPALKAR GLTTFGAVLT EVRKHGRLMR

DMNA
Length:704
Mass (Da):75,683
Last modified:August 1, 1998 - v1
Checksum:i8897BB3309E1ABA1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF010496 Genomic DNA Translation: AAC16131.1
CP001312 Genomic DNA Translation: ADE85851.1
PIRiT03478
RefSeqiWP_013067830.1, NC_014034.1

Genome annotation databases

EnsemblBacteriaiADE85851; ADE85851; RCAP_rcc02121
GeneIDi31490972
KEGGircp:RCAP_rcc02121

Similar proteinsi

Entry informationi

Entry nameiDPO3E_RHOCB
AccessioniPrimary (citable) accession number: O68045
Secondary accession number(s): D5AV69
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: August 1, 1998
Last modified: February 28, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health