Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative zinc metalloprotease aq_1964

Gene

aq_1964

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Cofactori

Zn2+Curated

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi17Zinc; catalyticPROSITE-ProRule annotation1
Active sitei18PROSITE-ProRule annotation1
Metal bindingi21Zinc; catalyticPROSITE-ProRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionHydrolase, Metalloprotease, Protease
LigandMetal-binding, Zinc

Enzyme and pathway databases

BioCyciAAEO224324:G1G15-1404-MONOMER

Protein family/group databases

MEROPSiM50.004

Names & Taxonomyi

Protein namesi
Recommended name:
Putative zinc metalloprotease aq_1964 (EC:3.4.24.-)
Gene namesi
Ordered Locus Names:aq_1964
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei88 – 110HelicalSequence analysisAdd BLAST23
Transmembranei369 – 391HelicalSequence analysisAdd BLAST23
Transmembranei406 – 428HelicalSequence analysisAdd BLAST23

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000884271 – 429Putative zinc metalloprotease aq_1964Add BLAST429

Interactioni

Protein-protein interaction databases

STRINGi224324.aq_1964

Structurei

Secondary structure

1429
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi118 – 121Combined sources4
Beta strandi122 – 129Combined sources8
Helixi134 – 137Combined sources4
Beta strandi145 – 149Combined sources5
Helixi157 – 169Combined sources13
Beta strandi174 – 181Combined sources8
Beta strandi184 – 191Combined sources8
Helixi195 – 197Combined sources3
Beta strandi203 – 205Combined sources3
Beta strandi209 – 214Combined sources6
Helixi219 – 222Combined sources4
Beta strandi230 – 234Combined sources5
Helixi242 – 250Combined sources9
Turni252 – 254Combined sources3
Beta strandi257 – 263Combined sources7
Beta strandi266 – 272Combined sources7
Beta strandi275 – 277Combined sources3
Turni278 – 281Combined sources4
Beta strandi282 – 284Combined sources3
Beta strandi286 – 289Combined sources4

3D structure databases

ProteinModelPortaliO67776
SMRiO67776
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini189 – 265PDZPROSITE-ProRule annotationAdd BLAST77

Sequence similaritiesi

Belongs to the peptidase M50B family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DZP Bacteria
COG0750 LUCA
HOGENOMiHOG000006281
InParanoidiO67776
KOiK11749
OMAiMFLGLFN
OrthoDBiPOG091H0131

Family and domain databases

InterProiView protein in InterPro
IPR001478 PDZ
IPR036034 PDZ_sf
IPR004387 Pept_M50_Zn
IPR008915 Peptidase_M50
PfamiView protein in Pfam
PF00595 PDZ, 1 hit
PF13180 PDZ_2, 1 hit
PF02163 Peptidase_M50, 1 hit
SMARTiView protein in SMART
SM00228 PDZ, 2 hits
SUPFAMiSSF50156 SSF50156, 2 hits
TIGRFAMsiTIGR00054 TIGR00054, 1 hit
PROSITEiView protein in PROSITE
PS50106 PDZ, 1 hit
PS00142 ZINC_PROTEASE, 1 hit

Sequencei

Sequence statusi: Complete.

O67776-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLIAFLILI GVLVWVHEFG HFLMAKLFRV KVEIFSIGFG PPIFRRQWGE
60 70 80 90 100
TVYQIAALPL GGYVKLYGEE ENVHDPRAFS TKKPWQKILI ALGGPLFNFL
110 120 130 140 150
FTILVFALVY TAGVEVPKYL KEPVVVGYVQ RDSIAQKIGI KPGDKIIKIN
160 170 180 190 200
GYEVRTWEDL RDALIRLSLD GVKETTLFLE RNGEVLHLTI KVPNVQKGEE
210 220 230 240 250
LGIAPLVKPV VGGVKKGSPA DQVGIKPGDL ILEVNGKKIN TWYELVEEVR
260 270 280 290 300
KSQGKAIKLK ILRNGKMIEK ELIPAKDPKT GTYFIGLFPK TETVVEKKPF
310 320 330 340 350
GEALASAVNR TWELTVLTLK TIAGLITGKV SFQTLGGPIA IAQIAGQAAQ
360 370 380 390 400
SGFIPYLVMM AFISLQLGIF NLIPLPILDG GLILLFAIEW LRGRPLPEKF
410 420
KEYWQRVGLA IIITLTIFVF INDILRLLR
Length:429
Mass (Da):47,792
Last modified:August 1, 1998 - v1
Checksum:i4EB336169F7D613B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA Translation: AAC07743.1
PIRiD70468
RefSeqiNP_214345.1, NC_000918.1
WP_010881281.1, NC_000918.1

Genome annotation databases

EnsemblBacteriaiAAC07743; AAC07743; aq_1964
GeneIDi1193673
KEGGiaae:aq_1964
PATRICifig|224324.8.peg.1515

Similar proteinsi

Entry informationi

Entry nameiY1964_AQUAE
AccessioniPrimary (citable) accession number: O67776
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2002
Last sequence update: August 1, 1998
Last modified: February 28, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Peptidase families
    Classification of peptidase families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health