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Protein

Sec-independent protein translocase protein TatC

Gene

tatC

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processProtein transport, Translocation, Transport

Enzyme and pathway databases

BioCyciAAEO224324:G1G15-900-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Sec-independent protein translocase protein TatCUniRule annotation
Gene namesi
Name:tatCUniRule annotation
Ordered Locus Names:aq_1267
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

  • Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei15 – 35HelicalUniRule annotationAdd BLAST21
Transmembranei61 – 81HelicalUniRule annotationAdd BLAST21
Transmembranei103 – 123HelicalUniRule annotationAdd BLAST21
Transmembranei152 – 172HelicalUniRule annotationAdd BLAST21
Transmembranei191 – 211HelicalUniRule annotationAdd BLAST21
Transmembranei212 – 232HelicalUniRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000980931 – 240Sec-independent protein translocase protein TatCAdd BLAST240

Interactioni

Subunit structurei

Forms a complex with TatA.UniRule annotation

Protein-protein interaction databases

STRINGi224324.aq_1267

Structurei

Secondary structure

1240
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi6 – 30Combined sources25
Helixi32 – 46Combined sources15
Beta strandi56 – 58Combined sources3
Helixi60 – 88Combined sources29
Turni89 – 92Combined sources4
Turni97 – 100Combined sources4
Helixi101 – 120Combined sources20
Helixi122 – 128Combined sources7
Turni129 – 131Combined sources3
Beta strandi133 – 135Combined sources3
Beta strandi138 – 141Combined sources4
Helixi146 – 163Combined sources18
Helixi166 – 175Combined sources10
Helixi181 – 202Combined sources22
Helixi206 – 225Combined sources20

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4B4AX-ray3.50A1-240[»]
4HTSX-ray4.00A1-232[»]
4HTTX-ray6.80A/B1-235[»]
SMRiO67305
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TatC family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiENOG4105DCX Bacteria
COG0805 LUCA
HOGENOMiHOG000245380
InParanoidiO67305
KOiK03118
OMAiEMSFLDH
OrthoDBiPOG091H02DA

Family and domain databases

HAMAPiMF_00902 TatC, 1 hit
InterProiView protein in InterPro
IPR019820 Sec-indep_translocase_CS
IPR002033 TatC
PANTHERiPTHR30371 PTHR30371, 1 hit
PfamiView protein in Pfam
PF00902 TatC, 1 hit
PRINTSiPR01840 TATCFAMILY
TIGRFAMsiTIGR00945 tatC, 1 hit
PROSITEiView protein in PROSITE
PS01218 TATC, 1 hit

Sequencei

Sequence statusi: Complete.

O67305-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPLTEHLREL RYRLIISIIA FLIGSGIAFY FAKYVFEILK EPILKSYPEV
60 70 80 90 100
ELITLSPTEP LFILIKISLA VGFIIASPVI LYQFWRFIEP ALYSHEKRAF
110 120 130 140 150
IPLLLGSILL FMLGALFAYF IVLPLALKFL LGLGFTQLLA TPYLSVDMYI
160 170 180 190 200
SFVLKLVVAF GIAFEMPIVL YVLQKAGVIT PEQLASFRKY FIVIAFVIGA
210 220 230 240
IIAPDVSTQV LMAIPLLLLY EISIFLGKLA TRKKKEIQKA
Length:240
Mass (Da):27,129
Last modified:August 1, 1998 - v1
Checksum:iFC3125C54D5B9047
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA Translation: AAC07267.1
PIRiF70409
RefSeqiNP_213869.1, NC_000918.1
WP_010880807.1, NC_000918.1

Genome annotation databases

EnsemblBacteriaiAAC07267; AAC07267; aq_1267
GeneIDi1192743
KEGGiaae:aq_1267
PATRICifig|224324.8.peg.988

Entry informationi

Entry nameiTATC_AQUAE
AccessioniPrimary (citable) accession number: O67305
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: February 28, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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