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UniProtKB - O67139 (SELD_AQUAE)
Protein
Selenide, water dikinase
Gene
selD
Organism
Aquifex aeolicus (strain VF5)
Status
Functioni
Synthesizes selenophosphate from selenide and ATP.
UniRule annotationCatalytic activityi
- EC:2.7.9.3UniRule annotation
Cofactori
Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per monomer.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Active sitei | 13 | UniRule annotation | 1 | |
Binding sitei | 16 | ATPUniRule annotation | 1 | |
Sitei | 16 | Important for catalytic activityUniRule annotation | 1 | |
Metal bindingi | 44 | MagnesiumUniRule annotation | 1 | |
Binding sitei | 60 | ATPUniRule annotation | 1 | |
Metal bindingi | 83 | MagnesiumUniRule annotation | 1 | |
Binding sitei | 83 | ATPUniRule annotation | 1 | |
Metal bindingi | 219 | MagnesiumUniRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 41 – 43 | ATPUniRule annotation | 3 | |
Nucleotide bindingi | 131 – 133 | ATP; shared with dimeric partnerUniRule annotation | 3 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-UniRule
- magnesium ion binding Source: UniProtKB-UniRule
- selenide, water dikinase activity Source: GO_Central
GO - Biological processi
- selenocysteine biosynthetic process Source: GO_Central
Keywordsi
Molecular function | Kinase, Transferase |
Ligand | ATP-binding, Magnesium, Metal-binding, Nucleotide-binding, Selenium |
Enzyme and pathway databases
BRENDAi | 2.7.9.3, 396 |
Names & Taxonomyi
Protein namesi | Recommended name: Selenide, water dikinaseUniRule annotation (EC:2.7.9.3UniRule annotation)Alternative name(s): Selenium donor proteinUniRule annotation Selenophosphate synthaseUniRule annotation |
Gene namesi | Name:selDUniRule annotation Ordered Locus Names:aq_1030 |
Organismi | Aquifex aeolicus (strain VF5) |
Taxonomic identifieri | 224324 [NCBI] |
Taxonomic lineagei | Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000127614 | 1 – 336 | Selenide, water dikinaseAdd BLAST | 336 |
Interactioni
Subunit structurei
Homodimer.
UniRule annotationProtein-protein interaction databases
STRINGi | 224324.aq_1030 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | O67139 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | O67139 |
Family & Domainsi
Sequence similaritiesi
Phylogenomic databases
eggNOGi | COG0709, Bacteria |
HOGENOMi | CLU_032859_0_1_0 |
InParanoidi | O67139 |
OMAi | DNEPKYG |
OrthoDBi | 882590at2 |
Family and domain databases
CDDi | cd02195, SelD, 1 hit |
Gene3Di | 3.30.1330.10, 1 hit 3.90.650.10, 1 hit |
HAMAPi | MF_00625, SelD, 1 hit |
InterProi | View protein in InterPro IPR010918, PurM-like_C_dom IPR036676, PurM-like_C_sf IPR016188, PurM-like_N IPR036921, PurM-like_N_sf IPR023061, SelD_I IPR004536, SPS/SelD |
PANTHERi | PTHR10256, PTHR10256, 1 hit |
Pfami | View protein in Pfam PF00586, AIRS, 1 hit PF02769, AIRS_C, 1 hit |
PIRSFi | PIRSF036407, Selenphspht_syn, 1 hit |
SUPFAMi | SSF55326, SSF55326, 1 hit SSF56042, SSF56042, 1 hit |
TIGRFAMsi | TIGR00476, selD, 1 hit |
i Sequence
Sequence statusi: Complete.
O67139-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVELLKLVRS SGUAAKVGPG DLQEILKGFN IYTDESTLVS IGDDAGVYEH
60 70 80 90 100
NGIIWVYTVD IITPVVNDPY LWGAISTANA LSDVYAMGGI PVNALAISCF
110 120 130 140 150
NNCELDIEIF REVIRGALDK LREAKTVLLG GHTIDDKEPK FGLSVAGICP
160 170 180 190 200
EGKYITQSGA QVGQLLILTK PIGTGILIKG LKEGILKEED INEAIENMLA
210 220 230 240 250
LNDKARNLML SLDATACTDV TGFGLLGHAW NICKNSNIGA RIFFEKVPYY
260 270 280 290 300
QLSENLVKKK IYPKGAIENL NFVKNYLKSN LDNWKLILLS DPVTSGGLLF
310 320 330
TINKEKLEKI DETAKELEVN YWIIGETIAE NVLEVL
Sequence cautioni
The sequence AAC07095 differs from that shown. Reason: Erroneous termination. Truncated C-terminus.Curated
Non-standard residue
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-standard residuei | 13 | SelenocysteineSequence analysis | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000657 Genomic DNA Translation: AAC07095.1 Sequence problems. |
PIRi | H70388 |
RefSeqi | NP_213702.1, NC_000918.1 |
Genome annotation databases
EnsemblBacteriai | AAC07095; AAC07095; aq_1030 |
KEGGi | aae:aq_1030 |
PATRICi | fig|224324.8.peg.804 |
Keywords - Coding sequence diversityi
SelenocysteineSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000657 Genomic DNA Translation: AAC07095.1 Sequence problems. |
PIRi | H70388 |
RefSeqi | NP_213702.1, NC_000918.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
2YYE | X-ray | 2.10 | A/B | 1-336 | [»] | |
2ZAU | X-ray | 2.00 | A/B/C | 27-336 | [»] | |
2ZOD | X-ray | 1.98 | A/B | 1-336 | [»] | |
SMRi | O67139 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 224324.aq_1030 |
Protocols and materials databases
DNASUi | 1193773 |
Genome annotation databases
EnsemblBacteriai | AAC07095; AAC07095; aq_1030 |
KEGGi | aae:aq_1030 |
PATRICi | fig|224324.8.peg.804 |
Phylogenomic databases
eggNOGi | COG0709, Bacteria |
HOGENOMi | CLU_032859_0_1_0 |
InParanoidi | O67139 |
OMAi | DNEPKYG |
OrthoDBi | 882590at2 |
Enzyme and pathway databases
BRENDAi | 2.7.9.3, 396 |
Miscellaneous databases
EvolutionaryTracei | O67139 |
Family and domain databases
CDDi | cd02195, SelD, 1 hit |
Gene3Di | 3.30.1330.10, 1 hit 3.90.650.10, 1 hit |
HAMAPi | MF_00625, SelD, 1 hit |
InterProi | View protein in InterPro IPR010918, PurM-like_C_dom IPR036676, PurM-like_C_sf IPR016188, PurM-like_N IPR036921, PurM-like_N_sf IPR023061, SelD_I IPR004536, SPS/SelD |
PANTHERi | PTHR10256, PTHR10256, 1 hit |
Pfami | View protein in Pfam PF00586, AIRS, 1 hit PF02769, AIRS_C, 1 hit |
PIRSFi | PIRSF036407, Selenphspht_syn, 1 hit |
SUPFAMi | SSF55326, SSF55326, 1 hit SSF56042, SSF56042, 1 hit |
TIGRFAMsi | TIGR00476, selD, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | SELD_AQUAE | |
Accessioni | O67139Primary (citable) accession number: O67139 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | February 26, 2008 | |
Last modified: | September 29, 2021 | |
This is version 131 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families