UniProtKB - O67135 (O67135_AQUAE)
Protein
Acetoin utilization protein AcuC
Gene
acuC1
Organism
Aquifex aeolicus (strain VF5)
Status
Functioni
: acetoin degradation Pathwayi
This protein is involved in the pathway acetoin degradation, which is part of Ketone degradation.ARBA annotationView all proteins of this organism that are known to be involved in the pathway acetoin degradation and in Ketone degradation.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 168 | ZincCombined sources | 1 | |
Metal bindingi | 170 | Zinc; via pros nitrogenCombined sources | 1 | |
Metal bindingi | 258 | ZincCombined sources | 1 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- acetoin catabolic process Source: UniProtKB-UniPathway
Keywordsi
Biological process | Acetoin catabolismARBA annotation |
Ligand | Metal-bindingCombined sources, ZincCombined sources |
Enzyme and pathway databases
BioCyci | AAEO224324:G1G15-725-MONOMER |
BRENDAi | 3.5.1.98, 396 |
UniPathwayi | UPA00040 |
Names & Taxonomyi
Protein namesi | Recommended name: Acetoin utilization protein AcuCARBA annotation |
Gene namesi | Name:acuC1Imported Ordered Locus Names:aq_1023Imported |
Organismi | Aquifex aeolicus (strain VF5)Imported |
Taxonomic identifieri | 224324 [NCBI] |
Taxonomic lineagei | Bacteria › Aquificae › Aquificales › Aquificaceae › Aquifex › |
Proteomesi |
|
Structurei
3D structure databases
SMRi | O67135 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | O67135 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 21 – 310 | Hist_deacetylInterPro annotationAdd BLAST | 290 |
Sequence similaritiesi
Belongs to the histone deacetylase family.ARBA annotation
Phylogenomic databases
eggNOGi | COG0123, Bacteria |
HOGENOMi | CLU_007727_8_0_0 |
InParanoidi | O67135 |
OMAi | GWLRAFH |
OrthoDBi | 1443295at2 |
Family and domain databases
CDDi | cd09994, HDAC_AcuC_like, 1 hit |
Gene3Di | 3.40.800.20, 1 hit |
InterProi | View protein in InterPro IPR003085, AcuC IPR000286, His_deacetylse IPR023801, His_deacetylse_dom IPR037138, His_deacetylse_dom_sf IPR023696, Ureohydrolase_dom_sf |
Pfami | View protein in Pfam PF00850, Hist_deacetyl, 1 hit |
PRINTSi | PR01270, HDASUPER |
SUPFAMi | SSF52768, SSF52768, 1 hit |
i Sequence
Sequence statusi: Complete.
O67135-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKKVKLIGTL DYGKYRYPKN HPLKIPRVSL LLRFLDAMNL IDEKELIKSR
60 70 80 90 100
PATKEELLLF HTEDYINTLM EAERCQCVPK GAREKYNIGG YENPVSYAMF
110 120 130 140 150
TGSSLATGST VQAIEEFLKG NVAFNPAGGM HHAFKSRANG FCYINDPAVG
160 170 180 190 200
IEYLRKKGFK RILYIDLDAH HCDGVQEAFY DTDQVFVLSL HQSPEYAFPF
210 220 230 240 250
EKGFLEEIGE GKGKGYNLNI PLPKGLNDNE FLFALEKSLE IVKEVFEPEV
260 270 280 290 300
YLLQLGTDPL LEDYLSKFNL SNVAFLKAFN IVREVFGEGV YLGGGGYHPY
310 320 330 340 350
ALARAWTLIW CELSGREVPE KLNNKAKELL KSIDFEEFDD EVDRSYMLET
360 370
LKDPWRGGEV RKEVKDTLEK AKASS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000657 Genomic DNA Translation: AAC07100.1 |
PIRi | D70388 |
RefSeqi | NP_213698.1, NC_000918.1 WP_010880636.1, NC_000918.1 |
Genome annotation databases
EnsemblBacteriai | AAC07100; AAC07100; aq_1023 |
KEGGi | aae:aq_1023 |
PATRICi | fig|224324.8.peg.800 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AE000657 Genomic DNA Translation: AAC07100.1 |
PIRi | D70388 |
RefSeqi | NP_213698.1, NC_000918.1 WP_010880636.1, NC_000918.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1C3P | X-ray | 1.80 | A | 1-375 | [»] | |
1C3R | X-ray | 2.00 | A/B | 1-375 | [»] | |
1C3S | X-ray | 2.50 | A | 1-375 | [»] | |
SMRi | O67135 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
STRINGi | 224324.aq_1023 |
Chemistry databases
DrugBanki | DB04297, Trichostatin A DB02546, Vorinostat |
Genome annotation databases
EnsemblBacteriai | AAC07100; AAC07100; aq_1023 |
KEGGi | aae:aq_1023 |
PATRICi | fig|224324.8.peg.800 |
Phylogenomic databases
eggNOGi | COG0123, Bacteria |
HOGENOMi | CLU_007727_8_0_0 |
InParanoidi | O67135 |
OMAi | GWLRAFH |
OrthoDBi | 1443295at2 |
Enzyme and pathway databases
UniPathwayi | UPA00040 |
BioCyci | AAEO224324:G1G15-725-MONOMER |
BRENDAi | 3.5.1.98, 396 |
Miscellaneous databases
EvolutionaryTracei | O67135 |
Family and domain databases
CDDi | cd09994, HDAC_AcuC_like, 1 hit |
Gene3Di | 3.40.800.20, 1 hit |
InterProi | View protein in InterPro IPR003085, AcuC IPR000286, His_deacetylse IPR023801, His_deacetylse_dom IPR037138, His_deacetylse_dom_sf IPR023696, Ureohydrolase_dom_sf |
Pfami | View protein in Pfam PF00850, Hist_deacetyl, 1 hit |
PRINTSi | PR01270, HDASUPER |
SUPFAMi | SSF52768, SSF52768, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | O67135_AQUAE | |
Accessioni | O67135Primary (citable) accession number: O67135 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 1, 1998 |
Last sequence update: | August 1, 1998 | |
Last modified: | December 2, 2020 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |