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Protein

Phosphate-specific transport system accessory protein PhoU homolog

Gene

phoU

Organism
Aquifex aeolicus (strain VF5)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Plays a role in the regulation of phosphate uptake. In this role, it may bind, possibly as a chaperone, to PhoR, PhoB or a PhoR-PhoB complex to promote dephosphorylation of phospho-PhoB, or inhibit formation of the PhoR-PhoB transitory complex (Probable).Curated

GO - Molecular functioni

  • protein homodimerization activity Source: UniProtKB

GO - Biological processi

Keywordsi

Biological processPhosphate transport, Transport

Enzyme and pathway databases

BioCyciAAEO224324:G1G15-641-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphate-specific transport system accessory protein PhoU homolog
Short name:
Pst system accessory protein PhoU homolog
Alternative name(s):
PhoU-like phosphate uptake regulator
Gene namesi
Name:phoU
Ordered Locus Names:aq_906
OrganismiAquifex aeolicus (strain VF5)
Taxonomic identifieri224324 [NCBI]
Taxonomic lineageiBacteriaAquificaeAquificalesAquificaceaeAquifex
Proteomesi
  • UP000000798 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: UniProtKB

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001551631 – 221Phosphate-specific transport system accessory protein PhoU homologAdd BLAST221

Interactioni

Subunit structurei

Homodimer.1 Publication

GO - Molecular functioni

  • protein homodimerization activity Source: UniProtKB

Protein-protein interaction databases

STRINGi224324.aq_906

Structurei

Secondary structure

1221
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi1 – 33Combined sources33
Helixi37 – 45Combined sources9
Helixi47 – 68Combined sources22
Helixi72 – 106Combined sources35
Helixi115 – 136Combined sources22
Helixi140 – 170Combined sources31
Helixi172 – 174Combined sources3
Helixi175 – 208Combined sources34

3D structure databases

ProteinModelPortaliO67053
SMRiO67053
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiO67053

Family & Domainsi

Sequence similaritiesi

Belongs to the PhoU family.Curated

Phylogenomic databases

eggNOGiENOG4108UTW Bacteria
COG0704 LUCA
HOGENOMiHOG000074026
InParanoidiO67053
KOiK02039
OMAiHATNIGQ
OrthoDBiPOG091H01TR

Family and domain databases

Gene3Di1.20.58.220, 2 hits
InterProiView protein in InterPro
IPR028366 P_transport_PhoU
IPR038078 PhoU-like_sf
IPR026022 PhoU_dom
PANTHERiPTHR42930:SF3 PTHR42930:SF3, 1 hit
PfamiView protein in Pfam
PF01895 PhoU, 2 hits
PIRSFiPIRSF003107 PhoU, 1 hit
TIGRFAMsiTIGR02135 phoU_full, 1 hit

Sequencei

Sequence statusi: Complete.

O67053-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLFKELEET KEQVIKMAKL VQEAIDKATE ALNKQNVELA EEVIKGDDTI
60 70 80 90 100
DLLEVDIERR CIRMIALYQP EAGDLRMIMG IYKIVSDLER MGDEAENIAE
110 120 130 140 150
RAILLAEEPP LKPYVNINFM SEIVKEMVND SVISFIQQDT LLAKKVIEKD
160 170 180 190 200
DTVDELYHQL ERELMTYVLE DPRNIKRAMH LSFVARHYER IADHAENVAE
210 220
AAIYLSEGEI VKHQHIKEKG E
Length:221
Mass (Da):25,567
Last modified:August 1, 1998 - v1
Checksum:i42C83425B0EB5D84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE000657 Genomic DNA Translation: AAC07012.1
PIRiB70378
RefSeqiNP_213615.1, NC_000918.1
WP_010880553.1, NC_000918.1

Genome annotation databases

EnsemblBacteriaiAAC07012; AAC07012; aq_906
GeneIDi1193595
KEGGiaae:aq_906
PATRICifig|224324.8.peg.707

Entry informationi

Entry nameiPHOU_AQUAE
AccessioniPrimary (citable) accession number: O67053
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: August 1, 1998
Last modified: March 28, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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