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Protein

SMR domain-containing protein At5g58720

Gene

PIPC

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
SMR domain-containing protein At5g58720Curated
Alternative name(s):
PRL1-interacting protein PIPC1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:PIPC1 Publication
Ordered Locus Names:At5g58720Imported
ORF Names:MZN1.16Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Arabidopsis Information Portal

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Araporti
AT5G58720

The Arabidopsis Information Resource

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TAIRi
locus:2178878 AT5G58720

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004345651 – 519SMR domain-containing protein At5g58720Add BLAST519

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

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PaxDbi
O65573

PRoteomics IDEntifications database

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PRIDEi
O65573

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
O65573 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
O65573 AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with PRL1.1 Publication

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
O65573, 25 interactors

STRING: functional protein association networks

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STRINGi
3702.AT5G58720.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
O65573

Database of comparative protein structure models

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ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini428 – 502SmrPROSITE-ProRule annotationAdd BLAST75

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi98 – 126Ser-richPROSITE-ProRule annotationAdd BLAST29

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
KOG2401 Eukaryota
ENOG41101K4 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000064626

Identification of Orthologs from Complete Genome Data

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OMAi
KAAMAYS

Database of Orthologous Groups

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OrthoDBi
EOG09360BG1

Database for complete collections of gene phylogenies

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PhylomeDBi
O65573

Family and domain databases

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR013899 DUF1771
IPR002625 Smr_dom
IPR036063 Smr_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08590 DUF1771, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM01162 DUF1771, 1 hit
SM00463 SMR, 1 hit

Superfamily database of structural and functional annotation

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SUPFAMi
SSF160443 SSF160443, 1 hit

PROSITE; a protein domain and family database

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PROSITEi
View protein in PROSITE
PS50828 SMR, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 1 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoform i produced by alternative splicing. AlignAdd to basket
Note: A number of isoforms are produced. According to EST sequences.Curated
Isoform 1 (identifier: O65573-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MKQKNQHKKK KKRSCAAKPS GDGTTSDGNK KDVEEERKDG EGKREIENVG
60 70 80 90 100
KNFIESLMEA FCSVSMEEAM AAYKEAGGDL NKAAEILSDL VESGDDPSTS
110 120 130 140 150
SVASGSSGQE TASTSEYGAG SSSSCSEDLT RDRWFKGSKQ SRVIAATGMV
160 170 180 190 200
SSVIAKDYLK PNPVRKEFPM MERSKELCGN GKKAADREKA EQFLSSMLGD
210 220 230 240 250
DCELSMAVVR DVLCQCGYDV DMALNVLLDM SSSSTDDSLS GKCFGIGVSD
260 270 280 290 300
SLAESSFDTD TSDCELFWGG DYSQRDYAKA LMSSQDPFAT TQGIDELGLP
310 320 330 340 350
QKVLESLFNI RQNPKHESKT TSWRNVAKKM QSLGIDASSS SGEEPHPNTF
360 370 380 390 400
VKDDSYHELR KGANDQWNVT KSYYQKAAEA YSKGGRAHAA YLSDKGRVAS
410 420 430 440 450
KQAQRADERA SQDIFVARNK GIENVVTIDL HGQHVKPAMK LLKLHLLFGS
460 470 480 490 500
YVPSIQTLRV ITGCGASGFG KSKVKQSVVK LLEREGVRYC EENRGTLLIK
510
LDGGSREFSF LDTESDSDE
Length:519
Mass (Da):56,654
Last modified:August 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1220DB469C4D87F8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti52 – 53NF → KI in AAM62636 (Ref. 5) Curated2
Sequence conflicti208V → F in AAM62636 (Ref. 5) Curated1
Sequence conflicti219D → N in AAM62636 (Ref. 5) Curated1
Sequence conflicti284 – 286SQD → FQH in AAM62636 (Ref. 5) Curated3

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AJ006021 mRNA Translation: CAA06808.1
AB020755 Genomic DNA Translation: BAA97340.1
CP002688 Genomic DNA Translation: AED97089.1
AY062752 mRNA Translation: AAL32830.1
AY114674 mRNA Translation: AAM47993.1
AY085409 mRNA Translation: AAM62636.1

Protein sequence database of the Protein Information Resource

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PIRi
T51367

NCBI Reference Sequences

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RefSeqi
NP_200680.1, NM_125259.4 [O65573-1]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
At.49190
At.7874

Genome annotation databases

Ensembl plant genome annotation project

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EnsemblPlantsi
AT5G58720.1; AT5G58720.1; AT5G58720 [O65573-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
835986

Gramene; a comparative resource for plants

More...
Gramenei
AT5G58720.1; AT5G58720.1; AT5G58720 [O65573-1]

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ath:AT5G58720

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ006021 mRNA Translation: CAA06808.1
AB020755 Genomic DNA Translation: BAA97340.1
CP002688 Genomic DNA Translation: AED97089.1
AY062752 mRNA Translation: AAL32830.1
AY114674 mRNA Translation: AAM47993.1
AY085409 mRNA Translation: AAM62636.1
PIRiT51367
RefSeqiNP_200680.1, NM_125259.4 [O65573-1]
UniGeneiAt.49190
At.7874

3D structure databases

ProteinModelPortaliO65573
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO65573, 25 interactors
STRINGi3702.AT5G58720.1

Proteomic databases

PaxDbiO65573
PRIDEiO65573

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT5G58720.1; AT5G58720.1; AT5G58720 [O65573-1]
GeneIDi835986
GrameneiAT5G58720.1; AT5G58720.1; AT5G58720 [O65573-1]
KEGGiath:AT5G58720

Organism-specific databases

AraportiAT5G58720
TAIRilocus:2178878 AT5G58720

Phylogenomic databases

eggNOGiKOG2401 Eukaryota
ENOG41101K4 LUCA
HOGENOMiHOG000064626
OMAiKAAMAYS
OrthoDBiEOG09360BG1
PhylomeDBiO65573

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O65573

Gene expression databases

ExpressionAtlasiO65573 baseline and differential
GenevisibleiO65573 AT

Family and domain databases

InterProiView protein in InterPro
IPR013899 DUF1771
IPR002625 Smr_dom
IPR036063 Smr_dom_sf
PfamiView protein in Pfam
PF08590 DUF1771, 1 hit
SMARTiView protein in SMART
SM01162 DUF1771, 1 hit
SM00463 SMR, 1 hit
SUPFAMiSSF160443 SSF160443, 1 hit
PROSITEiView protein in PROSITE
PS50828 SMR, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiY5872_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O65573
Secondary accession number(s): Q8LEH8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 14, 2015
Last sequence update: August 1, 1998
Last modified: November 7, 2018
This is version 120 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
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