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Entry version 159 (18 Sep 2019)
Sequence version 1 (01 Aug 1998)
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Protein

Lactoylglutathione lyase GLX1

Gene

GLX1

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>This subsection of the ‘Function’ section provides information relevant to cofactors. A cofactor is any non-protein substance required for a protein to be catalytically active. Some cofactors are inorganic, such as the metal atoms zinc, iron, and copper in various oxidation states. Others, such as most vitamins, are organic.<p><a href='/help/cofactor' target='_top'>More...</a></p>Cofactori

Zn2+By similarityNote: Binds 1 zinc ion per subunit. In the homodimer, two zinc ions are bound between subunits.By similarity

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section describes the metabolic pathway(s) associated with a protein.<p><a href='/help/pathway' target='_top'>More...</a></p>Pathwayi: methylglyoxal degradation

This protein is involved in step 1 of the subpathway that synthesizes (R)-lactate from methylglyoxal.By similarity
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. Lactoylglutathione lyase (At1g08110), Lactoylglutathione lyase GLX1 (GLX1), Lactoylglutathione lyase (AXX17_At1g07880), Lactoylglutathione lyase (AXX17_At1g07880), Lactoylglutathione lyase (At1g08110), Probable lactoylglutathione lyase, chloroplastic (At1g67280), Lactoylglutathione lyase (At1g08110), Lactoylglutathione lyase (AXX17_At1g12200)
  2. Hydroxyacylglutathione hydrolase 1, mitochondrial (GLX2-1), Probable hydroxyacylglutathione hydrolase 2, chloroplastic (GLX2-4), Hydroxyacylglutathione hydrolase 2, mitochondrial (At2g31350), Hydroxyacylglutathione hydrolase cytoplasmic (GLX2-2)
This subpathway is part of the pathway methylglyoxal degradation, which is itself part of Secondary metabolite metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes (R)-lactate from methylglyoxal, the pathway methylglyoxal degradation and in Secondary metabolite metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi20Zinc; via tele nitrogenBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the interaction between a single amino acid and another chemical entity. Priority is given to the annotation of physiological ligands.<p><a href='/help/binding' target='_top'>More...</a></p>Binding sitei24SubstrateBy similarity1
Metal bindingi71ZincBy similarity1
Binding sitei75SubstrateBy similarity1
Metal bindingi89Zinc; via tele nitrogenBy similarity1
Binding sitei89SubstrateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei137Proton donor/acceptorPROSITE-ProRule annotation1
Metal bindingi137ZincBy similarity1
Metal bindingi150Divalent metal cationPROSITE-ProRule annotation1
Metal bindingi150Zinc; shared with dimeric partnerBy similarity1
Binding sitei150Substrate; shared with dimeric partnerBy similarity1
Binding sitei154Substrate; shared with dimeric partnerBy similarity1
Metal bindingi201Divalent metal cationPROSITE-ProRule annotation1
Metal bindingi201Zinc; shared with dimeric partnerBy similarity1
Binding sitei205Substrate; shared with dimeric partnerBy similarity1
Metal bindingi219Divalent metal cationPROSITE-ProRule annotation1
Metal bindingi271Divalent metal cationPROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDioxygenase, Lyase, Oxidoreductase
LigandManganese, Metal-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT1G11840-MONOMER

UniPathway: a resource for the exploration and annotation of metabolic pathways

More...
UniPathwayi
UPA00619;UER00675

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Lactoylglutathione lyase GLX11 Publication (EC:4.4.1.5By similarity)
Alternative name(s):
Glyoxalase I1 Publication
Short name:
AtGLX11 Publication
Short name:
GlyI1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:GLX11 Publication
Ordered Locus Names:At1g11840Imported
ORF Names:F12F1.32Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

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Araporti
AT1G11840

The Arabidopsis Information Resource

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TAIRi
locus:2008930 AT1G11840

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedCombined sources
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004411742 – 283Lactoylglutathione lyase GLX1Add BLAST282

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylalanineCombined sources1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Phosphorylated by SnRK2.8.1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PRoteomics IDEntifications database

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PRIDEi
O65398

Protein Mass spectra EXtraction

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ProMEXi
O65398

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
O65398

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
O65398

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O65398 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

By similarity

Protein-protein interaction databases

Protein interaction database and analysis system

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IntActi
O65398, 2 interactors

STRING: functional protein association networks

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STRINGi
3702.AT1G11840.6

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
O65398

Database of comparative protein structure models

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ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini17 – 141VOC 1PROSITE-ProRule annotationAdd BLAST125
Domaini147 – 275VOC 2PROSITE-ProRule annotationAdd BLAST129

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni251 – 252Substrate bindingBy similarity2

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the glyoxalase I family.Curated

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2943 Eukaryota
COG0346 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000232011

KEGG Orthology (KO)

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KOi
K01759

Identification of Orthologs from Complete Genome Data

More...
OMAi
DNIQAAC

Database of Orthologous Groups

More...
OrthoDBi
1513831at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O65398

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.10.180.10, 2 hits

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR029068 Glyas_Bleomycin-R_OHBP_Dase
IPR004360 Glyas_Fos-R_dOase_dom
IPR004361 Glyoxalase_1
IPR018146 Glyoxalase_1_CS
IPR037523 VOC

Pfam protein domain database

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Pfami
View protein in Pfam
PF00903 Glyoxalase, 2 hits

Superfamily database of structural and functional annotation

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SUPFAMi
SSF54593 SSF54593, 2 hits

TIGRFAMs; a protein family database

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TIGRFAMsi
TIGR00068 glyox_I, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00934 GLYOXALASE_I_1, 2 hits
PS00935 GLYOXALASE_I_2, 1 hit
PS51819 VOC, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: O65398-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MAEASDLLEW PKKDNRRFLH VVYRVGDLDR TIEFYTEVFG MKLLRKRDIP
60 70 80 90 100
EEKYSNAFLG FGPETSNFVV ELTYNYGVSS YDIGTGFGHF AISTQDVSKL
110 120 130 140 150
VENVRAKGGN VTREPGPVKG GGSVIAFVKD PDGYTFELIQ RGPTPEPFCQ
160 170 180 190 200
VMLRVGDLDR AIKFYEKALG MRLLRKIERP EYKYTIGMMG YAEEYESIVL
210 220 230 240 250
ELTYNYDVTE YTKGNAYAQI AIGTDDVYKS GEVIKIVNQE LGGKITREAG
260 270 280
PLPGLGTKIV SFLDPDGWKT VLVDNKDFLK ELE
Length:283
Mass (Da):31,928
Last modified:August 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA321FECFCD2EAFE9
GO
Isoform 2 (identifier: O65398-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-1: M → MNEIASASMLRLCQCFISICNVHFVSMRAAESSFLLSRNM

Note: Derived from EST data. No experimental confirmation available.Imported
Show »
Length:322
Mass (Da):36,292
Checksum:i211952679DF948B7
GO
Isoform 3 (identifier: O65398-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     220-232: IAIGTDDVYKSGE → AQMMCTKAVKLLR
     233-283: Missing.

Note: No experimental confirmation available.Imported
Show »
Length:232
Mass (Da):26,479
Checksum:iC5D2F0EC90E0A16E
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti40G → C in BAH19947 (PubMed:19423640).Curated1
Sequence conflicti45R → W in AAL07227 (PubMed:14593172).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0590321M → MNEIASASMLRLCQCFISIC NVHFVSMRAAESSFLLSRNM in isoform 2. 1
Alternative sequenceiVSP_059033220 – 232IAIGT…YKSGE → AQMMCTKAVKLLR in isoform 3. Add BLAST13
Alternative sequenceiVSP_059034233 – 283Missing in isoform 3. Add BLAST51

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC002131 Genomic DNA Translation: AAC17630.1
CP002684 Genomic DNA Translation: AEE28792.1
CP002684 Genomic DNA Translation: AEE28793.1
CP002684 Genomic DNA Translation: AEE28794.1
CP002684 Genomic DNA Translation: AEE28795.1
CP002684 Genomic DNA Translation: AEE28796.1
CP002684 Genomic DNA Translation: AEE28797.1
AB050553 mRNA Translation: BAB17665.1
AF428272 mRNA Translation: AAL16104.1
AY056148 mRNA Translation: AAL07227.1
AY074569 mRNA Translation: AAL67109.1
AY097360 mRNA Translation: AAM19876.1
AK316841 mRNA Translation: BAH19553.1
AK317270 mRNA Translation: BAH19947.1
AK318730 mRNA Translation: BAH56845.1
AY087874 mRNA Translation: AAM65426.1

Protein sequence database of the Protein Information Resource

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PIRi
F86252

NCBI Reference Sequences

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RefSeqi
NP_001031025.1, NM_001035948.1 [O65398-1]
NP_001031026.1, NM_001035949.3 [O65398-3]
NP_001184968.1, NM_001198039.1 [O65398-2]
NP_172648.1, NM_101055.4 [O65398-1]
NP_849643.1, NM_179312.4 [O65398-1]
NP_849644.2, NM_179313.2 [O65398-1]

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G11840.1; AT1G11840.1; AT1G11840 [O65398-1]
AT1G11840.2; AT1G11840.2; AT1G11840 [O65398-1]
AT1G11840.3; AT1G11840.3; AT1G11840 [O65398-1]
AT1G11840.4; AT1G11840.4; AT1G11840 [O65398-1]
AT1G11840.5; AT1G11840.5; AT1G11840 [O65398-3]
AT1G11840.6; AT1G11840.6; AT1G11840 [O65398-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
837731

Gramene; a comparative resource for plants

More...
Gramenei
AT1G11840.1; AT1G11840.1; AT1G11840 [O65398-1]
AT1G11840.2; AT1G11840.2; AT1G11840 [O65398-1]
AT1G11840.3; AT1G11840.3; AT1G11840 [O65398-1]
AT1G11840.4; AT1G11840.4; AT1G11840 [O65398-1]
AT1G11840.5; AT1G11840.5; AT1G11840 [O65398-3]
AT1G11840.6; AT1G11840.6; AT1G11840 [O65398-2]

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
ath:AT1G11840

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002131 Genomic DNA Translation: AAC17630.1
CP002684 Genomic DNA Translation: AEE28792.1
CP002684 Genomic DNA Translation: AEE28793.1
CP002684 Genomic DNA Translation: AEE28794.1
CP002684 Genomic DNA Translation: AEE28795.1
CP002684 Genomic DNA Translation: AEE28796.1
CP002684 Genomic DNA Translation: AEE28797.1
AB050553 mRNA Translation: BAB17665.1
AF428272 mRNA Translation: AAL16104.1
AY056148 mRNA Translation: AAL07227.1
AY074569 mRNA Translation: AAL67109.1
AY097360 mRNA Translation: AAM19876.1
AK316841 mRNA Translation: BAH19553.1
AK317270 mRNA Translation: BAH19947.1
AK318730 mRNA Translation: BAH56845.1
AY087874 mRNA Translation: AAM65426.1
PIRiF86252
RefSeqiNP_001031025.1, NM_001035948.1 [O65398-1]
NP_001031026.1, NM_001035949.3 [O65398-3]
NP_001184968.1, NM_001198039.1 [O65398-2]
NP_172648.1, NM_101055.4 [O65398-1]
NP_849643.1, NM_179312.4 [O65398-1]
NP_849644.2, NM_179313.2 [O65398-1]

3D structure databases

SMRiO65398
ModBaseiSearch...

Protein-protein interaction databases

IntActiO65398, 2 interactors
STRINGi3702.AT1G11840.6

PTM databases

iPTMnetiO65398
SwissPalmiO65398

Proteomic databases

PRIDEiO65398
ProMEXiO65398

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G11840.1; AT1G11840.1; AT1G11840 [O65398-1]
AT1G11840.2; AT1G11840.2; AT1G11840 [O65398-1]
AT1G11840.3; AT1G11840.3; AT1G11840 [O65398-1]
AT1G11840.4; AT1G11840.4; AT1G11840 [O65398-1]
AT1G11840.5; AT1G11840.5; AT1G11840 [O65398-3]
AT1G11840.6; AT1G11840.6; AT1G11840 [O65398-2]
GeneIDi837731
GrameneiAT1G11840.1; AT1G11840.1; AT1G11840 [O65398-1]
AT1G11840.2; AT1G11840.2; AT1G11840 [O65398-1]
AT1G11840.3; AT1G11840.3; AT1G11840 [O65398-1]
AT1G11840.4; AT1G11840.4; AT1G11840 [O65398-1]
AT1G11840.5; AT1G11840.5; AT1G11840 [O65398-3]
AT1G11840.6; AT1G11840.6; AT1G11840 [O65398-2]
KEGGiath:AT1G11840

Organism-specific databases

AraportiAT1G11840
TAIRilocus:2008930 AT1G11840

Phylogenomic databases

eggNOGiKOG2943 Eukaryota
COG0346 LUCA
HOGENOMiHOG000232011
KOiK01759
OMAiDNIQAAC
OrthoDBi1513831at2759
PhylomeDBiO65398

Enzyme and pathway databases

UniPathwayiUPA00619;UER00675
BioCyciARA:AT1G11840-MONOMER

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O65398

Gene expression databases

ExpressionAtlasiO65398 baseline and differential

Family and domain databases

Gene3Di3.10.180.10, 2 hits
InterProiView protein in InterPro
IPR029068 Glyas_Bleomycin-R_OHBP_Dase
IPR004360 Glyas_Fos-R_dOase_dom
IPR004361 Glyoxalase_1
IPR018146 Glyoxalase_1_CS
IPR037523 VOC
PfamiView protein in Pfam
PF00903 Glyoxalase, 2 hits
SUPFAMiSSF54593 SSF54593, 2 hits
TIGRFAMsiTIGR00068 glyox_I, 2 hits
PROSITEiView protein in PROSITE
PS00934 GLYOXALASE_I_1, 2 hits
PS00935 GLYOXALASE_I_2, 1 hit
PS51819 VOC, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiGLX1_ARATH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O65398
Secondary accession number(s): B9DFN6
, B9DGT0, F4IAH9, Q3EDE2, Q940A4
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 30, 2017
Last sequence update: August 1, 1998
Last modified: September 18, 2019
This is version 159 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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