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Protein

Putative pectate lyase 2

Gene

At1g11920

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

Eliminative cleavage of (1->4)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends.

Cofactori

Ca2+By similarityNote: Binds 1 Ca2+ ion. Required for its activity.By similarity

Pathwayi: pectin degradation

This protein is involved in step 2 of the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin.
Proteins known to be involved in the 5 steps of the subpathway in this organism are:
  1. Pectinesterase (PMEPCRA), Pectinesterase (AXX17_At2g44790), Pectinesterase (AXX17_At5g50300), Pectinesterase (AXX17_At5g20800), Pectinesterase (AXX17_At5g45990), Pectinesterase (AXX17_At3g55110), Pectinesterase (AXX17_At1g24390), Pectinesterase (AXX17_At3g06710), Pectinesterase (AXX17_At1g48300), Pectinesterase (AXX17_At4g00230), Pectinesterase (AXX17_At5g50310), Pectinesterase (AXX17_At2g33420), Pectinesterase (AXX17_At3g31890), Pectinesterase (PMEPCRF), Pectinesterase (At3g10720), Putative pectinesterase 10 (PME10), Putative pectinesterase 11 (PME11), Probable pectinesterase/pectinesterase inhibitor 12 (PME12), Probable pectinesterase/pectinesterase inhibitor 13 (PME13), Putative pectinesterase 14 (PME14), Probable pectinesterase 15 (PME15), Probable pectinesterase/pectinesterase inhibitor 16 (PME16), Probable pectinesterase/pectinesterase inhibitor 17 (PME17), Pectinesterase/pectinesterase inhibitor 18 (PME18), Probable pectinesterase/pectinesterase inhibitor 19 (PME19), Pectinesterase 1 (PME1), Probable pectinesterase/pectinesterase inhibitor 20 (PME20), Probable pectinesterase/pectinesterase inhibitor 21 (PME21), Putative pectinesterase/pectinesterase inhibitor 22 (PME22), Probable pectinesterase/pectinesterase inhibitor 23 (PME23), Putative pectinesterase/pectinesterase inhibitor 24 (PME24), Probable pectinesterase/pectinesterase inhibitor 25 (PME25), Putative pectinesterase/pectinesterase inhibitor 26 (PME26), Putative pectinesterase/pectinesterase inhibitor 28 (PME28), Probable pectinesterase 29 (PME29), Pectinesterase 2 (PME2), Probable pectinesterase 30 (PME30), Pectinesterase 31 (PME31), Probable pectinesterase/pectinesterase inhibitor 32 (PME32), Probable pectinesterase/pectinesterase inhibitor 33 (PME33), Probable pectinesterase/pectinesterase inhibitor 34 (PME34), Probable pectinesterase/pectinesterase inhibitor 35 (PME35), Probable pectinesterase/pectinesterase inhibitor 36 (PME36), Probable pectinesterase/pectinesterase inhibitor VGDH2 (VGDH2), Putative pectinesterase/pectinesterase inhibitor 38 (PME38), Probable pectinesterase/pectinesterase inhibitor 39 (PME39), Pectinesterase/pectinesterase inhibitor 3 (PME3), Probable pectinesterase/pectinesterase inhibitor 40 (PME40), Probable pectinesterase/pectinesterase inhibitor 41 (PME41), Probable pectinesterase/pectinesterase inhibitor 42 (PME42), Putative pectinesterase/pectinesterase inhibitor 43 (PME43), Probable pectinesterase/pectinesterase inhibitor 44 (PME44), Putative pectinesterase/pectinesterase inhibitor 45 (PME45), Probable pectinesterase/pectinesterase inhibitor 46 (PME46), Probable pectinesterase/pectinesterase inhibitor 47 (PME47), Probable pectinesterase 48 (PME48), Probable pectinesterase 49 (PME49), Pectinesterase 4 (PME4), Probable pectinesterase 50 (PME50), Probable pectinesterase/pectinesterase inhibitor 51 (PME51), Putative pectinesterase 52 (PME52), Probable pectinesterase 53 (PME53), Probable pectinesterase/pectinesterase inhibitor 54 (PME54), Probable pectinesterase 55 (PME55), Probable pectinesterase 56 (PME56), Putative pectinesterase 57 (PME57), Probable pectinesterase/pectinesterase inhibitor 58 (PME58), Probable pectinesterase/pectinesterase inhibitor 59 (PME59), Pectinesterase 5 (PME5), Probable pectinesterase/pectinesterase inhibitor 60 (PME60), Probable pectinesterase/pectinesterase inhibitor 61 (PME61), Pectinesterase QRT1 (QRT1), Putative pectinesterase 63 (PME63), Probable pectinesterase/pectinesterase inhibitor 64 (PME64), Probable pectinesterase 66 (PME66), Probable pectinesterase 67 (PME67), Probable pectinesterase 68 (PME68), Probable pectinesterase/pectinesterase inhibitor 6 (PME6), Probable pectinesterase/pectinesterase inhibitor 7 (PME7), Probable pectinesterase 8 (PME8), Pectinesterase PPME1 (PPME1), Pectinesterase (AXX17_At3g36460), Pectinesterase (AXX17_At4g06570), Pectinesterase (AXX17_At3g14900), Pectinesterase (AXX17_At3g30550), Pectinesterase (At3g14310), Pectinesterase (AXX17_At1g11890), Pectinesterase (AXX17_At4g18720), Pectinesterase (At4g15980), Pectinesterase (At3g49220), Pectinesterase (AXX17_At2g22270), Pectinesterase (AXX17_At4g38050), Uncharacterized protein (AXX17_At3g05180), Pectinesterase (AXX17_At5g47900), Pectinesterase, Pectinesterase (AXX17_At5g19650), Pectinesterase (AXX17_At3g43380), Pectinesterase (AXX17_At4g02900), Pectinesterase (AXX17_At2g42790), Pectinesterase (AXX17_At3g10570), Pectinesterase (AXX17_At3g56460), Plant invertase/pectin methylesterase inhibitor superfamily (At3g49220), Pectinesterase (AXX17_At4g02940), Pectinesterase (AXX17_At1g11900), PME26 (AXX17_At3g14890), Uncharacterized protein (AXX17_At5g27870), Uncharacterized protein (AXX17_At5g64270), Pectinesterase (AXX17_At1g04730), Pectinesterase (AXX17_At3g41380), Pectinesterase (AXX17_At5g04430), Pectinesterase, Pectinesterase (F14I3.7), Pectinesterase (AXX17_At2g22280), Pectinesterase, Pectinesterase (AXX17_At5g52320), Pectinesterase (AXX17_At2g33420), Pectinesterase, Pectinesterase (AXX17_At1g11920), Pectinesterase (AXX17_At2g40510), Pectinesterase (At5g20860), Pectinesterase (AXX17_At3g26070), Pectinesterase (AXX17_At3g10560), Pectinesterase (AXX17_At1g48290), Pectinesterase (AXX17_At1g01970), Pectinesterase (AXX17_At2g44780), Pectinesterase (AXX17_At4g38040), Pectinesterase (AXX17_At2g33410), Pectinesterase (AXX17_At5g04420), Pectinesterase (AXX17_At3g05190), Pectinesterase (AXX17_At3g53530), Pectinesterase (AXX17_At4g02930), Pectinesterase (AXX17_At3g17940), Pectinesterase (AXX17_At2g45340), Plant invertase/pectin methylesterase inhibitor superfamily (At5g09760), Pectinesterase (At5g26810), Pectinesterase (PME44), Pectinesterase (At1g53840)
  2. Pectate lyase (AXX17_At3g06910), Pectate lyase (At3g27400), Pectate lyase (AXX17_At3g26200), Pectate lyase (AXX17_At3g09180), Pectate lyase (AXX17_At3g49450), Pectate lyase (AXX17_At3g49720), Pectate lyase (AXX17_At4g25610), Putative pectate lyase 14 (At4g13210), Probable pectate lyase 19 (At5g15110), Probable pectate lyase 3 (AT59), Probable pectate lyase 5 (At1g67750), Probable pectate lyase 6 (At2g02720), Probable pectate lyase 7 (At3g01270), Probable pectate lyase 8 (At3g07010), Probable pectate lyase 9 (At3g24230), Probable pectate lyase 12 (At3g53190), Putative pectate lyase 17 (At4g22090), Probable pectate lyase 10 (At3g24670), Probable pectate lyase 13 (PMR6), Probable pectate lyase 1 (At1g04680), Probable pectate lyase 20 (At5g48900), Probable pectate lyase 4 (At1g30350), Probable pectate lyase 16 (At4g22080), Probable pectate lyase 18 (At4g24780), Putative pectate lyase 21 (At5g55720), Probable pectate lyase 22 (At5g63180), Putative pectate lyase 2 (At1g11920), Putative pectate lyase 11 (At3g27400), Probable pectate lyase 15 (At4g13710), Pectate lyase (At5g09280), Pectate lyase (At3g55140), Pectate lyase, Pectate lyase (At1g14420), Pectate lyase (F11F8_12), Pectate lyase (At5g04310), Pectate lyase (AXX17_At3g47590), Pectate lyase (At3g09540), Pectate lyase (AXX17_At5g54880), Pectate lyase, Pectate lyase (AXX17_At5g08800), Pectate lyase (AXX17_At1g04020), Pectate lyase (AXX17_At1g15010), Pectate lyase (AXX17_At1g12300), Pectate lyase (At3g01270), Pectate lyase (AXX17_At2g01680), Pectate lyase (At3g55140), Pectate lyase (AXX17_At3g00310), Pectate lyase (AXX17_At5g47570), Pectate lyase (AXX17_At5g03700), Pectate lyase (AXX17_At1g30780), Pectate lyase (T26I12.20), Pectate lyase (AXX17_At3g29900), Pectate lyase (At3g07010), Pectate lyase (AXX17_At5g14600), Pectate lyase (AXX17_At1g61710), Pectate lyase (AXX17_At5g62760), Pectate lyase (At3g07010), Pectate lyase (At3g01270), Pectate lyase, Pectate lyase (AXX17_At4g25600), Pectate lyase (At5g04310), Pectate lyase (AXX17_At4g14900), Pectate lyase (AXX17_At4g15660), Pectate lyase (At3g53190), Pectate lyase, Pectate lyase (At4g13710), Pectate lyase (At4g13210), Pectate lyase (At3g07010), Pectate lyase (AXX17_At3g26720), Pectate lyase
  3. no protein annotated in this organism
  4. no protein annotated in this organism
  5. no protein annotated in this organism
This subpathway is part of the pathway pectin degradation, which is itself part of Glycan metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 2-dehydro-3-deoxy-D-gluconate from pectin, the pathway pectin degradation and in Glycan metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi182CalciumBy similarity1
Metal bindingi206CalciumBy similarity1
Metal bindingi210CalciumBy similarity1
Active sitei262Sequence analysis1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase
LigandCalcium, Metal-binding

Enzyme and pathway databases

BioCyciARA:AT1G11920-MONOMER
UniPathwayi
UPA00545;UER00824

Protein family/group databases

CAZyiPL1 Polysaccharide Lyase Family 1

Names & Taxonomyi

Protein namesi
Recommended name:
Putative pectate lyase 2 (EC:4.2.2.2)
Gene namesi
Ordered Locus Names:At1g11920
ORF Names:F12F1.22
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G11920
TAIRilocus:2008925 AT1G11920

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_000002486624 – 384Putative pectate lyase 2Add BLAST361

Proteomic databases

PaxDbiO65388

Expressioni

Gene expression databases

ExpressionAtlasiO65388 baseline and differential
GenevisibleiO65388 AT

Interactioni

Protein-protein interaction databases

STRINGi3702.AT1G11920.1

Structurei

3D structure databases

ProteinModelPortaliO65388
SMRiO65388
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the polysaccharide lyase 1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IK4G Eukaryota
COG3866 LUCA
HOGENOMiHOG000237948
InParanoidiO65388
KOiK01728
OMAiHCYSGRI
OrthoDBiEOG09360DC6

Family and domain databases

Gene3Di2.160.20.10, 1 hit
InterProiView protein in InterPro
IPR018082 AmbAllergen
IPR002022 Pec_lyase
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
PfamiView protein in Pfam
PF00544 Pec_lyase_C, 1 hit
PRINTSiPR00807 AMBALLERGEN
SMARTiView protein in SMART
SM00656 Amb_all, 1 hit
SUPFAMiSSF51126 SSF51126, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

O65388-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASLFLTIIS LLFAAFSSSV VEAAYSNGYT IPKLLPNPID SCWRRNPYWA
60 70 80 90 100
SNRRALADCA VGFGKSAVGG KYGSIYVVTN PSDDPENPRP GTLRYAVIQS
110 120 130 140 150
KPLWITFARD MVIVLRNELI MNSYKTIDGR GAKVEIAYGP CITIQHVSHV
160 170 180 190 200
IIHGISIHDC KPGKSGRVRS SPTHVGSRKG SDGDAIAIFD SSHIWIDHCF
210 220 230 240 250
FSRCQDGLID VLHASTAVTI SNNYFTQHDK VMLLGHNDNN VEDKIMRVTI
260 270 280 290 300
AFNHFGPGLI ERMPRVRRGY AHVANNRYEK WQMYAIGGSA DPTIFSEGNY
310 320 330 340 350
FVASDDPSKK QVTKRIDSGY DWKRWKWRTS KDVFKNGAYF VPSGYGTVTP
360 370 380
LYGRAERFPV SHGSLVPLLT SSAGPLHCYS GRIC
Length:384
Mass (Da):42,693
Last modified:December 14, 2011 - v2
Checksum:i0BA653FC08194A21
GO

Sequence cautioni

The sequence AAC17625 differs from that shown. Reason: Erroneous gene model prediction.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002131 Genomic DNA Translation: AAC17625.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28815.1
PIRiH86253
RefSeqiNP_172656.1, NM_101064.2
UniGeneiAt.51578

Genome annotation databases

EnsemblPlantsiAT1G11920.1; AT1G11920.1; AT1G11920
GeneIDi837742
GrameneiAT1G11920.1; AT1G11920.1; AT1G11920
KEGGiath:AT1G11920

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC002131 Genomic DNA Translation: AAC17625.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE28815.1
PIRiH86253
RefSeqiNP_172656.1, NM_101064.2
UniGeneiAt.51578

3D structure databases

ProteinModelPortaliO65388
SMRiO65388
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT1G11920.1

Protein family/group databases

CAZyiPL1 Polysaccharide Lyase Family 1

Proteomic databases

PaxDbiO65388

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT1G11920.1; AT1G11920.1; AT1G11920
GeneIDi837742
GrameneiAT1G11920.1; AT1G11920.1; AT1G11920
KEGGiath:AT1G11920

Organism-specific databases

AraportiAT1G11920
TAIRilocus:2008925 AT1G11920

Phylogenomic databases

eggNOGiENOG410IK4G Eukaryota
COG3866 LUCA
HOGENOMiHOG000237948
InParanoidiO65388
KOiK01728
OMAiHCYSGRI
OrthoDBiEOG09360DC6

Enzyme and pathway databases

UniPathwayi
UPA00545;UER00824

BioCyciARA:AT1G11920-MONOMER

Miscellaneous databases

PROiPR:O65388

Gene expression databases

ExpressionAtlasiO65388 baseline and differential
GenevisibleiO65388 AT

Family and domain databases

Gene3Di2.160.20.10, 1 hit
InterProiView protein in InterPro
IPR018082 AmbAllergen
IPR002022 Pec_lyase
IPR012334 Pectin_lyas_fold
IPR011050 Pectin_lyase_fold/virulence
PfamiView protein in Pfam
PF00544 Pec_lyase_C, 1 hit
PRINTSiPR00807 AMBALLERGEN
SMARTiView protein in SMART
SM00656 Amb_all, 1 hit
SUPFAMiSSF51126 SSF51126, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiPLY2_ARATH
AccessioniPrimary (citable) accession number: O65388
Secondary accession number(s): F4IAK2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 16, 2003
Last sequence update: December 14, 2011
Last modified: November 7, 2018
This is version 116 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  3. PATHWAY comments
    Index of metabolic and biosynthesis pathways
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