UniProtKB - O64728 (STI_ARATH)
Protein
Protein STICHEL
Gene
STI
Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Functioni
Acts as a key regulator of trichome branching through an endoreduplication-independent pathway.5 Publications
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 490 – 497 | ATPSequence analysis | 8 |
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- DNA binding Source: InterPro
- DNA-directed DNA polymerase activity Source: InterPro
GO - Biological processi
- DNA-dependent DNA replication Source: GO_Central
- DNA repair Source: GO_Central
- trichome branching Source: UniProtKB
- trichome differentiation Source: TAIR
Keywordsi
Ligand | ATP-binding, Nucleotide-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Protein STICHEL |
Gene namesi | Name:STI Ordered Locus Names:At2g02480 ORF Names:T8K22.22 |
Organismi | Arabidopsis thaliana (Mouse-ear cress) |
Taxonomic identifieri | 3702 [NCBI] |
Taxonomic lineagei | Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliopsida › eudicotyledons › Gunneridae › Pentapetalae › rosids › malvids › Brassicales › Brassicaceae › Camelineae › Arabidopsis |
Proteomesi |
|
Organism-specific databases
Araporti | AT2G02480 |
TAIRi | locus:2065299, AT2G02480 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nucleus Source: GO_Central
Plasma Membrane
- plasma membrane Source: TAIR
Other locations
- DNA polymerase III complex Source: InterPro
- DNA replication factor C complex Source: GO_Central
Keywords - Cellular componenti
NucleusPathology & Biotechi
Disruption phenotypei
Shows trichomes with exclusively no branching.2 Publications
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000422976 | 1 – 1218 | Protein STICHELAdd BLAST | 1218 |
Proteomic databases
PaxDbi | O64728 |
PRIDEi | O64728 |
ProteomicsDBi | 228423 |
PTM databases
iPTMneti | O64728 |
Expressioni
Tissue specificityi
Ubiquitous.1 Publication
Inductioni
By gibberellin A3 (GA3).1 Publication
Gene expression databases
ExpressionAtlasi | O64728, baseline and differential |
Genevisiblei | O64728, AT |
Interactioni
Subunit structurei
Interacts with BLT.
1 PublicationProtein-protein interaction databases
BioGRIDi | 180, 2 interactors |
IntActi | O64728, 1 interactor |
STRINGi | 3702.AT2G02480.1 |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 762 – 788 | Sequence analysisAdd BLAST | 27 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 163 – 180 | Bipartite nuclear localization signalSequence analysisAdd BLAST | 18 | |
Motifi | 273 – 304 | PEST 1Add BLAST | 32 | |
Motifi | 425 – 449 | PEST 2Add BLAST | 25 | |
Motifi | 1178 – 1195 | Bipartite nuclear localization signalSequence analysisAdd BLAST | 18 | |
Motifi | 1196 – 1213 | Bipartite nuclear localization signalSequence analysisAdd BLAST | 18 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 104 – 110 | Poly-Glu | 7 | |
Compositional biasi | 878 – 882 | Poly-Ser | 5 |
Domaini
PEST motif is known to mediate rapid protein degradation.
Sequence similaritiesi
Belongs to the DnaX/STICHEL family.Curated
Keywords - Domaini
Coiled coil, RepeatPhylogenomic databases
eggNOGi | KOG0989, Eukaryota |
HOGENOMi | CLU_009072_0_0_1 |
InParanoidi | O64728 |
OMAi | MTTSCVI |
OrthoDBi | 97895at2759 |
PhylomeDBi | O64728 |
Family and domain databases
InterProi | View protein in InterPro IPR008921, DNA_pol3_clamp-load_cplx_C IPR022754, DNA_pol_III_gamma-3 IPR012763, DNA_pol_III_sug/sutau IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF12169, DNA_pol3_gamma3, 1 hit |
SUPFAMi | SSF48019, SSF48019, 1 hit SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR02397, dnaX_nterm, 1 hit |
i Sequence
Sequence statusi: Complete.
O64728-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSGSRVSDLS KLHLKKELTQ IRKAGRVLRD PGTTSSWKSP LDSSRSVALL
60 70 80 90 100
ETPASRNGGS SSQFPIRGES STNRRGKEKK VFLYNWKTQK SSSEKSGLAK
110 120 130 140 150
NGKEEEEEEE DASSWTQASV NDDDDVSDAR NGGDSYRREI QSASMGFRCR
160 170 180 190 200
DTNLASQGVS KMRKSNVGSC KKKSKKKISS SRLDCLSKYQ PRDDIVARNC
210 220 230 240 250
NAGSDDTEEE LSNSEDLRKV TGASPLLLKL KQKNWSRSSS RLLRANNRKE
260 270 280 290 300
DSSCTYNSTP ALSTSSYNMY AVRNPSTVGS WDGTTTSVND GDDELDDNLD
310 320 330 340 350
LPGRQGCGIP CYWTKKAMKH RGGCRSCCSP SFSDTLRRTG SSILCGSQSV
360 370 380 390 400
YRRHNRHSSG GYSKQKIACR SAQGVLPLLS YGGDGRGGSS LGTGLSDDEL
410 420 430 440 450
STNYGELDLE AQSRLDGRRW STSYRSQDGL EAVALDGEEE EGSTPETIRS
460 470 480 490 500
FSQKYRPMFF EELIGQSIVV QSLMNAVKRS RIAPVYLFQG PRGTGKTSTA
510 520 530 540 550
RIFSAALNCV ATEEMKPCGY CKECNDFMSG KSKDFWELDG ANKKGADKVR
560 570 580 590 600
YLLKNLPTIL PRNSSMYKVF VIDECHLLPS KTWLSFLKFL ENPLQKVVFI
610 620 630 640 650
FITTDLENVP RTIQSRCQKF LFDKLKDSDI VVRLKKIASD ENLDVDLHAL
660 670 680 690 700
DLIAMNADGS LRDAETMLEQ LSLLGKRITT ALVNELVGVV SDEKLLELLE
710 720 730 740 750
LALSSDTAET VKRARELLDL GADPIVLMSQ LASLIMDIIA GTYKVVDEKY
760 770 780 790 800
SNAFFDGRNL TEADMEGLKH ALKLLSEAEK QLRVSNDRST WFTATLLQLG
810 820 830 840 850
SMPSPGTTHT GSSRRQSSRA TDDDPASVSR EVMAYKQRIG GLHFSKSASP
860 870 880 890 900
ASVIKRNGNH SHEAKPFSRV IDNNCYKSSS SSQMIESEGS IASHENSIAS
910 920 930 940 950
TMMLNQRSSE KLNDIWRKCI ERCHSKTLRQ LLYTHGKLIS ISEVEGILVA
960 970 980 990 1000
YIAFGENDIK LRAERFLSSI TNSIEMVLRR SVEVRIILLP ETELLVVPHQ
1010 1020 1030 1040 1050
TRKPEMTNKS GHLNNIAGLN AETDVEVGSS VESRSKLPMQ RIESIIREQR
1060 1070 1080 1090 1100
LETAWLQTAD KDTPGSIIRV KPERNQILPQ EDTYRQTNVA SAISSSGLTT
1110 1120 1130 1140 1150
HQWVDELNNE VKLLKIGDNG ELQENLTGTR GQHCPLSPSL LHDTNFGNNK
1160 1170 1180 1190 1200
DNLGGYESGS GRVGCNILFC WNTKKTQRRS KSKQVKGTPV RSRRNRKSRF
1210
SLFNGCAKPR KAEGNIRR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF264023 mRNA Translation: AAF82285.1 AC004136 Genomic DNA Translation: AAC18938.2 CP002685 Genomic DNA Translation: AEC05585.1 CP002685 Genomic DNA Translation: ANM62557.1 |
PIRi | T00615 |
RefSeqi | NP_001324706.1, NM_001335120.1 NP_565285.1, NM_126303.3 |
Genome annotation databases
EnsemblPlantsi | AT2G02480.1; AT2G02480.1; AT2G02480 AT2G02480.2; AT2G02480.2; AT2G02480 |
GeneIDi | 814777 |
Gramenei | AT2G02480.1; AT2G02480.1; AT2G02480 AT2G02480.2; AT2G02480.2; AT2G02480 |
KEGGi | ath:AT2G02480 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF264023 mRNA Translation: AAF82285.1 AC004136 Genomic DNA Translation: AAC18938.2 CP002685 Genomic DNA Translation: AEC05585.1 CP002685 Genomic DNA Translation: ANM62557.1 |
PIRi | T00615 |
RefSeqi | NP_001324706.1, NM_001335120.1 NP_565285.1, NM_126303.3 |
3D structure databases
SMRi | O64728 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 180, 2 interactors |
IntActi | O64728, 1 interactor |
STRINGi | 3702.AT2G02480.1 |
PTM databases
iPTMneti | O64728 |
Proteomic databases
PaxDbi | O64728 |
PRIDEi | O64728 |
ProteomicsDBi | 228423 |
Genome annotation databases
EnsemblPlantsi | AT2G02480.1; AT2G02480.1; AT2G02480 AT2G02480.2; AT2G02480.2; AT2G02480 |
GeneIDi | 814777 |
Gramenei | AT2G02480.1; AT2G02480.1; AT2G02480 AT2G02480.2; AT2G02480.2; AT2G02480 |
KEGGi | ath:AT2G02480 |
Organism-specific databases
Araporti | AT2G02480 |
TAIRi | locus:2065299, AT2G02480 |
Phylogenomic databases
eggNOGi | KOG0989, Eukaryota |
HOGENOMi | CLU_009072_0_0_1 |
InParanoidi | O64728 |
OMAi | MTTSCVI |
OrthoDBi | 97895at2759 |
PhylomeDBi | O64728 |
Miscellaneous databases
PROi | PR:O64728 |
Gene expression databases
ExpressionAtlasi | O64728, baseline and differential |
Genevisiblei | O64728, AT |
Family and domain databases
InterProi | View protein in InterPro IPR008921, DNA_pol3_clamp-load_cplx_C IPR022754, DNA_pol_III_gamma-3 IPR012763, DNA_pol_III_sug/sutau IPR027417, P-loop_NTPase |
Pfami | View protein in Pfam PF12169, DNA_pol3_gamma3, 1 hit |
SUPFAMi | SSF48019, SSF48019, 1 hit SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR02397, dnaX_nterm, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | STI_ARATH | |
Accessioni | O64728Primary (citable) accession number: O64728 Secondary accession number(s): Q9LKQ4 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 24, 2013 |
Last sequence update: | June 1, 2002 | |
Last modified: | October 7, 2020 | |
This is version 140 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Plant Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Arabidopsis thaliana
Arabidopsis thaliana: entries and gene names - SIMILARITY comments
Index of protein domains and families