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Entry version 164 (12 Aug 2020)
Sequence version 2 (01 May 1999)
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Protein

Putative cadmium/zinc-transporting ATPase HMA4

Gene

HMA4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in cadmium/zinc transport.Curated

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei4014-aspartylphosphate intermediateBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the 'Description' field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi601MagnesiumPROSITE-ProRule annotation1
Metal bindingi605MagnesiumPROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTranslocase
LigandATP-binding, Cadmium, Magnesium, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
ARA:AT2G19110-MONOMER

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.3.6.18, the p-type atpase (p-atpase) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Putative cadmium/zinc-transporting ATPase HMA4 (EC:7.2.2.12, EC:7.2.2.21)
Alternative name(s):
Protein HEAVY METAL ATPASE 4
Putative cadmium/zinc-transporting ATPase 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:HMA4
Ordered Locus Names:At2g19110
ORF Names:T20K24.12
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 2

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT2G19110

The Arabidopsis Information Resource

More...
TAIRi
locus:2059083, AT2G19110

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 93CytoplasmicSequence analysisAdd BLAST93
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei94 – 115HelicalSequence analysisAdd BLAST22
Topological domaini116 – 118ExtracellularSequence analysis3
Transmembranei119 – 138HelicalSequence analysisAdd BLAST20
Topological domaini139 – 145CytoplasmicSequence analysis7
Transmembranei146 – 166HelicalSequence analysisAdd BLAST21
Topological domaini167ExtracellularSequence analysis1
Transmembranei168 – 188HelicalSequence analysisAdd BLAST21
Topological domaini189 – 314CytoplasmicSequence analysisAdd BLAST126
Transmembranei315 – 337HelicalSequence analysisAdd BLAST23
Topological domaini338 – 345ExtracellularSequence analysis8
Transmembranei346 – 363HelicalSequence analysisAdd BLAST18
Topological domaini364 – 656CytoplasmicSequence analysisAdd BLAST293
Transmembranei657 – 676HelicalSequence analysisAdd BLAST20
Topological domaini677 – 680ExtracellularSequence analysis4
Transmembranei681 – 700HelicalSequence analysisAdd BLAST20
Topological domaini701 – 1172CytoplasmicSequence analysisAdd BLAST472

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000463991 – 1172Putative cadmium/zinc-transporting ATPase HMA4Add BLAST1172

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O64474

PRoteomics IDEntifications database

More...
PRIDEi
O64474

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
230352

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
O64474, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O64474, AT

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
1785, 1 interactor

Protein interaction database and analysis system

More...
IntActi
O64474, 1 interactor

STRING: functional protein association networks

More...
STRINGi
3702.AT2G19110.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11172
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
O64474

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
O64474

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini18 – 84HMAPROSITE-ProRule annotationAdd BLAST67

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1157 – 1169Poly-HisAdd BLAST13

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0207, Eukaryota

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_001771_3_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O64474

KEGG Orthology (KO)

More...
KOi
K01534

Identification of Orthologs from Complete Genome Data

More...
OMAi
HENAGLE

Database of Orthologous Groups

More...
OrthoDBi
649559at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O64474

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1110.10, 1 hit
3.40.50.1000, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR006121, HMA_dom
IPR036163, HMA_dom_sf
IPR027256, P-typ_ATPase_IB
IPR001757, P_typ_ATPase

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55008, SSF55008, 1 hit
SSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81665, SSF81665, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01525, ATPase-IB_hvy, 1 hit
TIGR01494, ATPase_P-type, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit
PS50846, HMA_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O64474-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MALQNKEEEK KKVKKLQKSY FDVLGICCTS EVPIIENILK SLDGVKEYSV
60 70 80 90 100
IVPSRTVIVV HDSLLISPFQ IAKALNEARL EANVRVNGET SFKNKWPSPF
110 120 130 140 150
AVVSGLLLLL SFLKFVYSPL RWLAVAAVAA GIYPILAKAF ASIKRPRIDI
160 170 180 190 200
NILVIITVIA TLAMQDFMEA AAVVFLFTIS DWLETRASYK ATSVMQSLMS
210 220 230 240 250
LAPQKAIIAE TGEEVEVDEV KVDTVVAVKA GETIPIDGIV VDGNCEVDEK
260 270 280 290 300
TLTGEAFPVP KQRDSTVWAG TINLNGYICV KTTSLAGDCV VAKMAKLVEE
310 320 330 340 350
AQSSKTKSQR LIDKCSQYYT PAIILVSACV AIVPVIMKVH NLKHWFHLAL
360 370 380 390 400
VVLVSGCPCG LILSTPVATF CALTKAATSG LLIKSADYLD TLSKIKIVAF
410 420 430 440 450
DKTGTITRGE FIVIDFKSLS RDINLRSLLY WVSSVESKSS HPMAATIVDY
460 470 480 490 500
AKSVSVEPRP EEVEDYQNFP GEGIYGKIDG NDIFIGNKKI ASRAGCSTVP
510 520 530 540 550
EIEVDTKGGK TVGYVYVGER LAGFFNLSDA CRSGVSQAMA ELKSLGIKTA
560 570 580 590 600
MLTGDNQAAA MHAQEQLGNV LDVVHGDLLP EDKSRIIQEF KKEGPTAMVG
610 620 630 640 650
DGVNDAPALA TADIGISMGI SGSALATQTG NIILMSNDIR RIPQAVKLAR
660 670 680 690 700
RARRKVVENV CLSIILKAGI LALAFAGHPL IWAAVLVDVG TCLLVIFNSM
710 720 730 740 750
LLLREKKKIG NKKCYRASTS KLNGRKLEGD DDYVVDLEAG LLTKSGNGQC
760 770 780 790 800
KSSCCGDKKN QENVVMMKPS SKTSSDHSHP GCCGDKKEEK VKPLVKDGCC
810 820 830 840 850
SEKTRKSEGD MVSLSSCKKS SHVKHDLKMK GGSGCCASKN EKGKEVVAKS
860 870 880 890 900
CCEKPKQQVE SVGDCKSGHC EKKKQAEDIV VPVQIIGHAL THVEIELQTK
910 920 930 940 950
ETCKTSCCDS KEKVKETGLL LSSENTPYLE KGVLIKDEGN CKSGSENMGT
960 970 980 990 1000
VKQSCHEKGC SDEKQTGEIT LASEEETDDQ DCSSGCCVNE GTVKQSFDEK
1010 1020 1030 1040 1050
KHSVLVEKEG LDMETGFCCD AKLVCCGNTE GEVKEQCRLE IKKEEHCKSG
1060 1070 1080 1090 1100
CCGEEIQTGE ITLVSEEETE STNCSTGCCV DKEEVTQTCH EKPASLVVSG
1110 1120 1130 1140 1150
LEVKKDEHCE SSHRAVKVET CCKVKIPEAC ASKCRDRAKR HSGKSCCRSY
1160 1170
AKELCSHRHH HHHHHHHHHV SA
Length:1,172
Mass (Da):127,209
Last modified:May 1, 1999 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1E913B9450443440
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ297264 mRNA Translation: CAC19544.1
AC002392 Genomic DNA Translation: AAD12041.1
CP002685 Genomic DNA Translation: AEC06848.1
CP002685 Genomic DNA Translation: ANM62252.1
CP002685 Genomic DNA Translation: ANM62253.1
AY096796 mRNA Translation: AAM19954.1

Protein sequence database of the Protein Information Resource

More...
PIRi
F84572

NCBI Reference Sequences

More...
RefSeqi
NP_001318247.1, NM_001335621.1
NP_001324425.1, NM_001335622.1
NP_179501.1, NM_127468.5

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT2G19110.1; AT2G19110.1; AT2G19110
AT2G19110.2; AT2G19110.2; AT2G19110
AT2G19110.3; AT2G19110.3; AT2G19110

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
816428

Gramene; a comparative resource for plants

More...
Gramenei
AT2G19110.1; AT2G19110.1; AT2G19110
AT2G19110.2; AT2G19110.2; AT2G19110
AT2G19110.3; AT2G19110.3; AT2G19110

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT2G19110

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ297264 mRNA Translation: CAC19544.1
AC002392 Genomic DNA Translation: AAD12041.1
CP002685 Genomic DNA Translation: AEC06848.1
CP002685 Genomic DNA Translation: ANM62252.1
CP002685 Genomic DNA Translation: ANM62253.1
AY096796 mRNA Translation: AAM19954.1
PIRiF84572
RefSeqiNP_001318247.1, NM_001335621.1
NP_001324425.1, NM_001335622.1
NP_179501.1, NM_127468.5

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2KKHNMR-A2-96[»]
SMRiO64474
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi1785, 1 interactor
IntActiO64474, 1 interactor
STRINGi3702.AT2G19110.1

Protein family/group databases

TCDBi3.A.3.6.18, the p-type atpase (p-atpase) superfamily

Proteomic databases

PaxDbiO64474
PRIDEiO64474
ProteomicsDBi230352

Genome annotation databases

EnsemblPlantsiAT2G19110.1; AT2G19110.1; AT2G19110
AT2G19110.2; AT2G19110.2; AT2G19110
AT2G19110.3; AT2G19110.3; AT2G19110
GeneIDi816428
GrameneiAT2G19110.1; AT2G19110.1; AT2G19110
AT2G19110.2; AT2G19110.2; AT2G19110
AT2G19110.3; AT2G19110.3; AT2G19110
KEGGiath:AT2G19110

Organism-specific databases

AraportiAT2G19110
TAIRilocus:2059083, AT2G19110

Phylogenomic databases

eggNOGiKOG0207, Eukaryota
HOGENOMiCLU_001771_3_1_1
InParanoidiO64474
KOiK01534
OMAiHENAGLE
OrthoDBi649559at2759
PhylomeDBiO64474

Enzyme and pathway databases

BioCyciARA:AT2G19110-MONOMER

Miscellaneous databases

EvolutionaryTraceiO64474

Protein Ontology

More...
PROi
PR:O64474

Gene expression databases

ExpressionAtlasiO64474, baseline and differential
GenevisibleiO64474, AT

Family and domain databases

Gene3Di3.40.1110.10, 1 hit
3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR023299, ATPase_P-typ_cyto_dom_N
IPR018303, ATPase_P-typ_P_site
IPR023298, ATPase_P-typ_TM_dom_sf
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR036412, HAD-like_sf
IPR023214, HAD_sf
IPR006121, HMA_dom
IPR036163, HMA_dom_sf
IPR027256, P-typ_ATPase_IB
IPR001757, P_typ_ATPase
SUPFAMiSSF55008, SSF55008, 1 hit
SSF56784, SSF56784, 1 hit
SSF81653, SSF81653, 1 hit
SSF81665, SSF81665, 1 hit
TIGRFAMsiTIGR01525, ATPase-IB_hvy, 1 hit
TIGR01494, ATPase_P-type, 1 hit
PROSITEiView protein in PROSITE
PS00154, ATPASE_E1_E2, 1 hit
PS50846, HMA_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiHMA4_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O64474
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 11, 2001
Last sequence update: May 1, 1999
Last modified: August 12, 2020
This is version 164 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
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