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Protein
Submitted name:

Piwi-like protein

Gene

wago-4

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • chromatin silencing by small RNA Source: WormBase

Keywordsi

Biological processRNA-mediated gene silencingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Piwi-like proteinImported
Gene namesi
Name:wago-4Imported
ORF Names:CELE_F58G1.1Imported, F58G1.1Imported
OrganismiCaenorhabditis elegansImported
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
Proteomesi
  • UP000001940 Componenti: Chromosome II

Organism-specific databases

WormBaseiF58G1.1 ; CE17921 ; WBGene00010263 ; wago-4

PTM / Processingi

Proteomic databases

EPDiO62275
PaxDbiO62275
PeptideAtlasiO62275

Expressioni

Gene expression databases

BgeeiWBGene00010263 Expressed in 4 organ(s), highest expression level in multi-cellular organism

Interactioni

Protein-protein interaction databases

IntActiO62275, 1 interactor
STRINGi6239.F58G1.1

Structurei

3D structure databases

ProteinModelPortaliO62275
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini317 – 428PAZInterPro annotationAdd BLAST112
Domaini594 – 924PiwiInterPro annotationAdd BLAST331

Sequence similaritiesi

Belongs to the argonaute family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1041 Eukaryota
ENOG410XP07 LUCA
GeneTreeiENSGT00760000119148
HOGENOMiHOG000018952
InParanoidiO62275
OMAiAWDLNIA
OrthoDBiEOG091G03P1
PhylomeDBiO62275

Family and domain databases

Gene3Di3.30.420.10, 1 hit
InterProiView protein in InterPro
IPR003100 PAZ_dom
IPR036085 PAZ_dom_sf
IPR003165 Piwi
IPR012337 RNaseH-like_sf
IPR036397 RNaseH_sf
PfamiView protein in Pfam
PF02170 PAZ, 1 hit
PF02171 Piwi, 1 hit
SMARTiView protein in SMART
SM00949 PAZ, 1 hit
SM00950 Piwi, 1 hit
SUPFAMiSSF101690 SSF101690, 1 hit
SSF53098 SSF53098, 2 hits
PROSITEiView protein in PROSITE
PS50821 PAZ, 1 hit
PS50822 PIWI, 1 hit

Sequencei

Sequence statusi: Complete.

O62275-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPALPPVYTP SGAPSSVHAP PAVPPVPVPT QPLRSEYQTS NDACIKRLEE
60 70 80 90 100
LNIAPAAKLY PTPTEPGKCG VEAEIQTNVF GIEMHQDSLF YQYSVNITTE
110 120 130 140 150
LKNGKEVTFT KKGKDDFVVT ERHDKCCAIL FRALGDYEEF FKTSDSCLIY
160 170 180 190 200
DGQSILFSNV DLFQGFREGA VKTKYMQLDG GEMDHKDLKS LPCIKLEVFP
210 220 230 240 250
TKNPAVKFTR EAVARRATDS NLDSVSLAYQ QILELALTQP CLRNTARYVV
260 270 280 290 300
FDHGKMFFID PLGEGFEKCD VVDVGDGKQV VPGLKKTINF IEGPYGRGRS
310 320 330 340 350
NPSVVIDGMK VAFHKNQPIL DKLKEITTQP VEHGLKGLEK DRCAAVIKGL
360 370 380 390 400
DCYSTYGGRE RHHKIEGIHH EGARNARFEL NDGGSCTVAQ YFEDVYNITL
410 420 430 440 450
RYPDTNLIVS KERGNINFYP MELLKISSHQ RVQIPQLTSA QSQKTTKESA
460 470 480 490 500
VLPDVRQRLI LTGKNAAQIS SDNEVLGKMG VSVCEDPLMV KGRSIPAVKL
510 520 530 540 550
ANAEIGANPI NVKDNKWRAN RFTRPATAPN VWAMYVVGTA STRITLDTLK
560 570 580 590 600
KFADEFAAMC KSKGVNMPAP ADISLIHMDA IESRLYDATK ANCTFVFIIT
610 620 630 640 650
DDSITTLHQR YKMIEKDTKM IVQDMKLSKA LSVINAGKRL TLENVINKTN
660 670 680 690 700
VKLGGSNYVF VDAKKQLDSH LIIGVGISAP PAGTKYAMEN KGVLNPNVIG
710 720 730 740 750
YAYNAQHNQE FSGDFVLNSA SQDTLAPIED IVMHSLNEYQ KFHDGGLPRR
760 770 780 790 800
VIVYRTGTSE GNHGSIMAYE IPLARAAMRD FSPDIQLVYI VVSKDHSFRF
810 820 830 840 850
FKPDLASLAS RPQATSSTAS RHSAMPAAPK AWDLNIAPGI LVDSIVTNPA
860 870 880 890 900
CKQFFLNSHI TLQGTAKTPL YTVLADDAKV SMTALEDITY KLCHLHQIVG
910 920 930 940 950
LPTSLPTPLY VANEYAKRGR NLWNEAVALN NVPTVSGPEA DRLKELTKSI
960
CYKASGDLTG RRVNA
Length:965
Mass (Da):106,509
Last modified:August 1, 1998 - v1
Checksum:iF6F2F46E1B502171
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284602 Genomic DNA Translation: CAB04524.1
PIRiT22933
RefSeqiNP_496751.1, NM_064350.5
UniGeneiCel.5750

Genome annotation databases

EnsemblMetazoaiF58G1.1; F58G1.1; WBGene00010263
GeneIDi174932
KEGGicel:CELE_F58G1.1
UCSCiF58G1.1 c. elegans

Similar proteinsi

Entry informationi

Entry nameiO62275_CAEEL
AccessioniPrimary (citable) accession number: O62275
Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: September 12, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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