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Entry version 176 (13 Nov 2019)
Sequence version 1 (01 Aug 1998)
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Protein
Submitted name:

Guanine nucleotide exchange factor UNC-73A

Gene

unc-73

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGuanine-nucleotide releasing factorSAAS annotation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-CEL-193648 NRAGE signals death through JNK
R-CEL-194840 Rho GTPase cycle
R-CEL-416476 G alpha (q) signalling events
R-CEL-416482 G alpha (12/13) signalling events
R-CEL-418885 DCC mediated attractive signaling

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Guanine nucleotide exchange factor UNC-73AImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:unc-73Imported
ORF Names:CELE_F55C7.7Imported, F55C7.7Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome I

Organism-specific databases

WormBase

More...
WormBasei
F55C7.7a ; CE19464 ; WBGene00006805 ; unc-73

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00006805 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.F55C7.7a

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1205 – 1385DHInterPro annotationAdd BLAST181
Domaini1572 – 1637SH3InterPro annotationAdd BLAST66
Domaini1809 – 1987DHInterPro annotationAdd BLAST179
Domaini2005 – 2113PHInterPro annotationAdd BLAST109
Domaini2305 – 2390Ig-likeInterPro annotationAdd BLAST86
Domaini2397 – 2488Fibronectin type-IIIInterPro annotationAdd BLAST92

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1628 – 1738DisorderedSequence analysisAdd BLAST111
Regioni2081 – 2104DisorderedSequence analysisAdd BLAST24
Regioni2130 – 2198DisorderedSequence analysisAdd BLAST69

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili763 – 783Sequence analysisAdd BLAST21
Coiled coili804 – 824Sequence analysisAdd BLAST21
Coiled coili1028 – 1048Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1643 – 1661PolarSequence analysisAdd BLAST19
Compositional biasi1670 – 1738PolarSequence analysisAdd BLAST69
Compositional biasi2082 – 2098PolarSequence analysisAdd BLAST17

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4240 Eukaryota
ENOG410XPCA LUCA

KEGG Orthology (KO)

More...
KOi
K08810

Identification of Orthologs from Complete Genome Data

More...
OMAi
MDMIREC

Database of Orthologous Groups

More...
OrthoDBi
5761at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063 FN3, 1 hit
cd00160 RhoGEF, 2 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.900.10, 2 hits
2.30.29.30, 2 hits
2.60.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR001331 GDS_CDC24_CS
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07679 I-set, 1 hit
PF00621 RhoGEF, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060 FN3, 1 hit
SM00233 PH, 2 hits
SM00325 RhoGEF, 2 hits
SM00516 SEC14, 1 hit
SM00326 SH3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48065 SSF48065, 2 hits
SSF48726 SSF48726, 1 hit
SSF49265 SSF49265, 1 hit
SSF50044 SSF50044, 1 hit
SSF52087 SSF52087, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00741 DH_1, 1 hit
PS50010 DH_2, 2 hits
PS50853 FN3, 1 hit
PS50835 IG_LIKE, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS50002 SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 8 potential isoforms that are computationally mapped.Show allAlign All

O61528-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGDYDGKMTM KAEDILHVLR DGIAVLPGGR CRAGQAVIVC PSREQPVNQD
60 70 80 90 100
NLRNVFLYLF EVTSKMAREK GFLVVIDMRG KQTWTNVRHI LKALSSIESS
110 120 130 140 150
STVQVFIIKP EKFWEKQKAQ MSLGTWDFEV EMISFESLIK IIDSSHLPKT
160 170 180 190 200
VGGSYPYDHD EWLELRLDLE KWIWNITEIM EKLESVRREI CEGEQPVDVT
210 220 230 240 250
TANAALKKSQ HAKNSIFNVP VEGIETEGNK IATRILKPSK GVKNPDLEAT
260 270 280 290 300
TPYISNLTDS LRLLKGEVAK NWEVRQMELS KVYQQKQFER DAEHMIETLR
310 320 330 340 350
PYKKACERSM GDVGGCANDV VRLSAEFEQF QIAVRGMEVS VKQVFDKENH
360 370 380 390 400
LRTIGARNQI TDHVAARLAE EWHLVKELME RRSAVLHNAK EFFTSAQRYF
410 420 430 440 450
AEVPRWTAQP GVNPNDVLFN QESLEEAIRK HDAFWAQVEE VYAQAYDDAS
460 470 480 490 500
KVTRALKEAD AEDNVAREHS SRLQRAHKQL MEKWKERQVL LHHMLAMIAF
510 520 530 540 550
ETDVRLVVDW LEQHGEPYLR RNIHIGENVN QARSFQRNHT NFQRVAANTY
560 570 580 590 600
GNVQKLHQVY QDVTKSGSKI CDVDTMHGLM TDLSAKIEKF TKIENSRELL
610 620 630 640 650
LRQSVLFHTH YKELTDWYGK MGEKYKDRRI DLTVPTCDKN KERFVLETDE
660 670 680 690 700
TAQAYAMTID EGKTLIEMMQ RATRVFDVDY SASVAHIQLL ISDIEDKNTQ
710 720 730 740 750
ISSEWSPRRT LLHIASKFAM FEQNQFEVLE QIKSWEVDMR EMAESDSFYD
760 770 780 790 800
KADSVLPFHK DNQQQVRNAI ADIQKSAKEL SQALYSQKLT DLRDKRDRVV
810 820 830 840 850
LEAIREHVRE LEIAESRVMT YANETSMRMQ AASEVGDLRR ISNSVCKLID
860 870 880 890 900
NQLSALTQLG VIPNDYNDTV QKQEELRAFR DAVQHKLKEP YDAFVIRFRE
910 920 930 940 950
LMENRLANRD EVVYHNEAIQ AKYCRLMNLC EDRNKLLKSA HGCYKTYETA
960 970 980 990 1000
VLPILNQLES EYHSPTVTDW CAGCTSSIDA DRAAYVADLL SKHMDYKERF
1010 1020 1030 1040 1050
GKGCTYALRN GDFLLRYIRR STVNQSERKR HETKIADMKN NIRERQSNIL
1060 1070 1080 1090 1100
ELWMQKKLLL EGCQSFIFIE ASAKELLEFM KGEGNRKLKH FEKKGRREST
1110 1120 1130 1140 1150
DDDDEFAKFK SEVKQKKTDI QTFLMLSTNE TMSRGVHGDE IDRCIEQVKD
1160 1170 1180 1190 1200
EFSRFSRRVG DCEVVLRGEN GSTQSSKDEF SLDRHSDTAI FNEKKINERR
1210 1220 1230 1240 1250
EENRKMLEPM RELIQSERDY IKDLERCVNI YVKEFDQAAK NGTIPTLNPL
1260 1270 1280 1290 1300
KYEIFGNIEK IFKFHNDKLL HELIKYENQP EAVGASFIVW IDLLNELYTE
1310 1320 1330 1340 1350
YCVNKEQKNH VIATPDAVSF FTGIRERHGL EINNEIASLL IKPVQRITRY
1360 1370 1380 1390 1400
RLLIEQLMRS CTDKTNDLKE AYEVVCSVPR KVNDLIHYNC LDLKDFKVDE
1410 1420 1430 1440 1450
LGPFVTQDTL TFWEPRAYFK GRGKERQVFL FDISIVFAKR IEVSPKNIKY
1460 1470 1480 1490 1500
VIKGKPLPLS EVSIVEHVEG DTCRFGLRVG TVSSNDNRID LKANNHHTKV
1510 1520 1530 1540 1550
KWVQKIRDLT AGMLPLGLGV SEAYSVGTLS TARSVSVRSG ASTSSGGENR
1560 1570 1580 1590 1600
QSQDVESLLR HRYSVHSCDS EQSSEVWIVT ADFDGQVEGH LTVHKGDRVE
1610 1620 1630 1640 1650
IVEDQATDCA EYVQVVLCDQ PTKHGLVPAS IIAPPESGSV PDRPDDSNAS
1660 1670 1680 1690 1700
GSTVSKRKSL RRIFANSSKE RAAAANSSSS NNNSPATRQS TSTSSPVTAN
1710 1720 1730 1740 1750
GHTTESSTSA PIGVLSSGEP TSSNSIPSSS TPTHTVPSSV PATVIPIVVA
1760 1770 1780 1790 1800
EDEKAEDCLP PPMENITINN SIDEKDMNED SVAASDAVEP EVALPAKVEK
1810 1820 1830 1840 1850
TPEETARFKR SYVLMELVET EQDYVKDLTS VVEGYIGNLN KMDLPADLVG
1860 1870 1880 1890 1900
KDKIIFANIV NILEFHKTNF LKEIEKCSEN YEAAGAAFVK YERRLHTLYV
1910 1920 1930 1940 1950
TYCQNKPKSD YLLAQDDFEA FFADTKAKLG HKVALCDLLI KPVQRIMKYQ
1960 1970 1980 1990 2000
LLLKDILKFT ERAKDKTDTL KKALQVMHVV PKACDDMMQV GRLQNFDKSL
2010 2020 2030 2040 2050
SAQGKLIHQG TLQISESIAG NVQKPKDRRI FLFEQSAIIA DHIPPKKEFG
2060 2070 2080 2090 2100
NPTYIFKSQF MVNKMVFEPN VPDDPLRFVI KSSDPTQPTS FIANAQSQEE
2110 2120 2130 2140 2150
KDEWNRKMSE LLDQQKRLLA ALVDPRRYND MSSGMGDLSL GAPGGDRRGA
2160 2170 2180 2190 2200
PSSANRSAAS SSKKPAESPK KEGKSKSSLF SFGKKPAKSP TSPPPLDAAA
2210 2220 2230 2240 2250
AGKFQKVADD QVNLETDEKV KVLDVKNGYA SVKKADGTVG KCPSYFLTMS
2260 2270 2280 2290 2300
DIPGTNFAEQ IQYRREWQRR VDETDVEYGP SAFDTATSST DNFDVLLELT
2310 2320 2330 2340 2350
TCERPVVVED MKDIEVVEGN DVEMCPIISS HTDFTVIWHG PAVDSKRARI
2360 2370 2380 2390 2400
QTNQLNSRLL IKHVKKCDAG AYSVIAKNSF GVTSTVAFLS VISIPDPPTD
2410 2420 2430 2440 2450
FTVKISGDHE VRLKWKAESG LKYCIEYRIL DDSSPENWLI ASTNIEKTHV
2460 2470 2480
SLRNFARNSY SFRVFAYNQR VRSAPSQCIC ICFDGTEM
Length:2,488
Mass (Da):282,879
Last modified:August 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iFEF3F93525465C37
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
C4ALD5C4ALD5_CAEEL
Uncharacterized protein
unc-73 CELE_F55C7.7, F55C7.7
2,140Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q7KPP4Q7KPP4_CAEEL
Guanine nucleotide exchange factor ...
unc-73 CELE_F55C7.7, F55C7.7
1,638Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q7JNG4Q7JNG4_CAEEL
Uncharacterized protein
unc-73 CELE_F55C7.7, F55C7.7
552Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q7JNG6Q7JNG6_CAEEL
Uncharacterized protein
unc-73 CELE_F55C7.7, F55C7.7
928Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q95Q51Q95Q51_CAEEL
Uncharacterized protein
unc-73 CELE_F55C7.7, F55C7.7
633Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H2KYM2H2KYM2_CAEEL
Uncharacterized protein
unc-73 CELE_F55C7.7, F55C7.7
638Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H2KYM4H2KYM4_CAEEL
Uncharacterized protein
unc-73 CELE_F55C7.7, F55C7.7
923Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H2KYM3H2KYM3_CAEEL
Uncharacterized protein
unc-73 CELE_F55C7.7, F55C7.7
646Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF048834 mRNA Translation: AAC12931.1
BX284601 Genomic DNA Translation: CCD63876.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A87749
D87749
T34428
T42739

NCBI Reference Sequences

More...
RefSeqi
NP_001021496.1, NM_001026325.1

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
F55C7.7a.1; F55C7.7a.1; WBGene00006805

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
171988

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_F55C7.7

UCSC genome browser

More...
UCSCi
F55C7.7c c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF048834 mRNA Translation: AAC12931.1
BX284601 Genomic DNA Translation: CCD63876.1
PIRiA87749
D87749
T34428
T42739
RefSeqiNP_001021496.1, NM_001026325.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi6239.F55C7.7a

Genome annotation databases

EnsemblMetazoaiF55C7.7a.1; F55C7.7a.1; WBGene00006805
GeneIDi171988
KEGGicel:CELE_F55C7.7
UCSCiF55C7.7c c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
171988
WormBaseiF55C7.7a ; CE19464 ; WBGene00006805 ; unc-73

Phylogenomic databases

eggNOGiKOG4240 Eukaryota
ENOG410XPCA LUCA
KOiK08810
OMAiMDMIREC
OrthoDBi5761at2759

Enzyme and pathway databases

ReactomeiR-CEL-193648 NRAGE signals death through JNK
R-CEL-194840 Rho GTPase cycle
R-CEL-416476 G alpha (q) signalling events
R-CEL-416482 G alpha (12/13) signalling events
R-CEL-418885 DCC mediated attractive signaling

Gene expression databases

BgeeiWBGene00006805 Expressed in 4 organ(s), highest expression level in pharyngeal muscle cell (C elegans)

Family and domain databases

CDDicd00063 FN3, 1 hit
cd00160 RhoGEF, 2 hits
Gene3Di1.20.900.10, 2 hits
2.30.29.30, 2 hits
2.60.40.10, 2 hits
InterProiView protein in InterPro
IPR001251 CRAL-TRIO_dom
IPR036865 CRAL-TRIO_dom_sf
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR003961 FN3_dom
IPR036116 FN3_sf
IPR001331 GDS_CDC24_CS
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR013098 Ig_I-set
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF07679 I-set, 1 hit
PF00621 RhoGEF, 2 hits
SMARTiView protein in SMART
SM00060 FN3, 1 hit
SM00233 PH, 2 hits
SM00325 RhoGEF, 2 hits
SM00516 SEC14, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF48065 SSF48065, 2 hits
SSF48726 SSF48726, 1 hit
SSF49265 SSF49265, 1 hit
SSF50044 SSF50044, 1 hit
SSF52087 SSF52087, 1 hit
PROSITEiView protein in PROSITE
PS00741 DH_1, 1 hit
PS50010 DH_2, 2 hits
PS50853 FN3, 1 hit
PS50835 IG_LIKE, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS50002 SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO61528_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O61528
Secondary accession number(s): O61529, P91339
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: August 1, 1998
Last sequence update: August 1, 1998
Last modified: November 13, 2019
This is version 176 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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