UniProtKB - O61307 (TENM_DROME)
Protein
Teneurin-m
Gene
Ten-m
Organism
Drosophila melanogaster (Fruit fly)
Status
Functioni
Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Acts as a homophilic and heterophilic synaptic cell adhesion molecule that drives synapse assembly. Promotes bi-directional trans-synaptic signaling with Ten-a to organize neuromuscular synapses. Functions in olfactory synaptic partner matching by promoting homophilic cell adhesion between pre-synaptic olfactory receptor neurons (ORN) axons and post-synaptic projection neurons (PN) dendrites partner in the developing antennal lobe to form stable connections. Also required for peripheral axon growth cone guidance and target recognition of motor neurons.4 Publications
Miscellaneous
The name odz (odd Oz) reflects the odd pair rule nature of the gene and Oz reflects the prominent expression of the gene in the brain, heart and neurons, corresponding to the three gifts that the Wizard of Oz bestowed.
GO - Molecular functioni
- filamin binding Source: FlyBase
- identical protein binding Source: FlyBase
- protein heterodimerization activity Source: UniProtKB
- protein homodimerization activity Source: UniProtKB
GO - Biological processi
- cell adhesion Source: UniProtKB-KW
- chaeta development Source: FlyBase
- compound eye corneal lens development Source: FlyBase
- compound eye morphogenesis Source: FlyBase
- compound eye photoreceptor development Source: FlyBase
- cytoplasmic microtubule organization Source: UniProtKB
- maintenance of alignment of postsynaptic density and presynaptic active zone Source: SynGO
- maintenance of presynaptic active zone structure Source: UniProtKB
- motor neuron axon guidance Source: FlyBase
- neuromuscular synaptic transmission Source: UniProtKB
- positive regulation of heterotypic cell-cell adhesion Source: UniProtKB
- positive regulation of locomotion Source: UniProtKB
- postsynaptic membrane organization Source: UniProtKB
- postsynaptic spectrin-associated cytoskeleton organization Source: SynGO
- presynaptic membrane organization Source: UniProtKB
- R7 cell development Source: FlyBase
- regulation of homotypic cell-cell adhesion Source: UniProtKB
- regulation of terminal button organization Source: UniProtKB
- synapse organization Source: UniProtKB
- synaptic growth at neuromuscular junction Source: FlyBase
- synaptic target attraction Source: FlyBase
- synaptic target recognition Source: UniProtKB
- synaptic vesicle membrane organization Source: UniProtKB
Keywordsi
Molecular function | Developmental protein |
Biological process | Cell adhesion, Neurogenesis |
Names & Taxonomyi
Protein namesi | Recommended name: Teneurin-mShort name: Tenm Alternative name(s): Odd Oz protein Tenascin-like protein |
Gene namesi | Name:Ten-m Synonyms:odz ORF Names:CG5723 |
Organismi | Drosophila melanogaster (Fruit fly) |
Taxonomic identifieri | 7227 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Brachycera › Muscomorpha › Ephydroidea › Drosophilidae › Drosophila › Sophophora › |
Proteomesi |
|
Organism-specific databases
FlyBasei | FBgn0004449, Ten-m |
Subcellular locationi
Plasma membrane
Other locations
- Cytoplasm
- synaptosome
- Membrane Curated; Single-pass membrane protein Curated
Note: Localizes at neuromuscular junction. Localizes in neuron cell bodies. Colocalizes with alpha-Spec at the membranous subsynaptic reticulum (SSR).
Extracellular region or secreted
- extracellular matrix Source: FlyBase
Plasma Membrane
- integral component of plasma membrane Source: FlyBase
- plasma membrane Source: FlyBase
- postsynaptic membrane Source: UniProtKB
Other locations
- cytoplasm Source: UniProtKB-SubCell
- neuromuscular junction Source: FlyBase
- neuron projection Source: UniProtKB-SubCell
- neuronal cell body Source: UniProtKB
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 229 | CytoplasmicSequence analysisAdd BLAST | 229 | |
Transmembranei | 230 – 250 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 251 – 2731 | ExtracellularSequence analysisAdd BLAST | 2481 |
Keywords - Cellular componenti
Cell junction, Cell membrane, Cytoplasm, Membrane, Postsynaptic cell membrane, Synapse, SynaptosomePathology & Biotechi
Disruption phenotypei
Shows peripheral motor neuron axon guidance defects.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000421021 | 1 – 2731 | Teneurin-mAdd BLAST | 2731 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 540 ↔ 549 | PROSITE-ProRule annotation | ||
Disulfide bondi | 545 ↔ 560 | PROSITE-ProRule annotation | ||
Disulfide bondi | 562 ↔ 571 | PROSITE-ProRule annotation | ||
Disulfide bondi | 578 ↔ 589 | PROSITE-ProRule annotation | ||
Disulfide bondi | 583 ↔ 594 | PROSITE-ProRule annotation | ||
Disulfide bondi | 596 ↔ 605 | PROSITE-ProRule annotation | ||
Disulfide bondi | 651 ↔ 664 | PROSITE-ProRule annotation | ||
Disulfide bondi | 666 ↔ 675 | PROSITE-ProRule annotation | ||
Disulfide bondi | 742 ↔ 752 | PROSITE-ProRule annotation | ||
Disulfide bondi | 746 ↔ 762 | PROSITE-ProRule annotation | ||
Disulfide bondi | 764 ↔ 773 | PROSITE-ProRule annotation | ||
Glycosylationi | 857 | N-linked (GlcNAc...) asparagine1 Publication | 1 |
Post-translational modificationi
Phosphorylated. Phosphorylation occurs at tyrosine residues.1 Publication
Proteolytically cleaved.1 Publication
Keywords - PTMi
Disulfide bond, GlycoproteinProteomic databases
PaxDbi | O61307 |
PeptideAtlasi | O61307 |
PRIDEi | O61307 |
PTM databases
iPTMneti | O61307 |
Expressioni
Tissue specificityi
Expressed in muscles and motor neurons (at protein level).1 Publication
Developmental stagei
Expressed in the central nervous system and heart. Expressed in the developing antennal lobe. Expressed in subset of matching olfactory receptor neurons (ORN) and projection neurons (PN) in select glomeruli between 12 to 48 hours after puparium formation (apf) (at protein level). Expressed in odd-numbered blastoderm parasegments, the central nervous system, muscle attachment points and tracheal precursor cells. Expressed in the ventral nerve cord, the cardiac mesoderm and epidermis at late embryonic stages. Expressed in all imaginal disks.4 Publications
Gene expression databases
Bgeei | FBgn0004449, Expressed in embryonic/larval hemocyte (Drosophila) and 42 other tissues |
ExpressionAtlasi | O61307, baseline and differential |
Genevisiblei | O61307, DM |
Interactioni
Subunit structurei
Homodimer. Heterodimer with Ten-a.
Interacts with Ten-a; the interaction occurs at the neuromuscular junction.
Interacts with alpha-Spec and cher.
3 PublicationsBinary interactionsi
O61307
With | #Exp. | IntAct |
---|---|---|
cher [Q9VEN1] | 4 | EBI-118556,EBI-133626 |
GO - Molecular functioni
- filamin binding Source: FlyBase
- identical protein binding Source: FlyBase
- protein heterodimerization activity Source: UniProtKB
- protein homodimerization activity Source: UniProtKB
Protein-protein interaction databases
BioGRIDi | 65699, 9 interactors |
IntActi | O61307, 705 interactors |
STRINGi | 7227.FBpp0297244 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 536 – 572 | EGF-like 1PROSITE-ProRule annotationAdd BLAST | 37 | |
Domaini | 574 – 606 | EGF-like 2PROSITE-ProRule annotationAdd BLAST | 33 | |
Domaini | 643 – 676 | EGF-like 3PROSITE-ProRule annotationAdd BLAST | 34 | |
Domaini | 738 – 774 | EGF-like 4PROSITE-ProRule annotationAdd BLAST | 37 | |
Repeati | 1160 – 1201 | NHL 1Add BLAST | 42 | |
Repeati | 1202 – 1246 | NHL 2Add BLAST | 45 | |
Repeati | 1391 – 1434 | NHL 3Add BLAST | 44 | |
Repeati | 1459 – 1502 | NHL 4Add BLAST | 44 | |
Repeati | 1618 – 1652 | YDSequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 317 – 368 | Ser-richAdd BLAST | 52 |
Sequence similaritiesi
Keywords - Domaini
EGF-like domain, Repeat, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG1225, Eukaryota KOG4659, Eukaryota |
GeneTreei | ENSGT01010000222317 |
HOGENOMi | CLU_000229_1_0_1 |
InParanoidi | O61307 |
OMAi | AHYKYAY |
Family and domain databases
Gene3Di | 2.120.10.30, 2 hits 2.60.120.260, 1 hit |
InterProi | View protein in InterPro IPR011042, 6-blade_b-propeller_TolB-like IPR008969, CarboxyPept-like_regulatory IPR000742, EGF-like_dom IPR008979, Galactose-bd-like_sf IPR031325, RHS_repeat IPR028916, Tox-GHH_dom IPR006530, YD |
Pfami | View protein in Pfam PF05593, RHS_repeat, 1 hit PF15636, Tox-GHH, 1 hit |
SMARTi | View protein in SMART SM00181, EGF, 8 hits |
SUPFAMi | SSF49464, SSF49464, 1 hit |
TIGRFAMsi | TIGR01643, YD_repeat_2x, 1 hit |
PROSITEi | View protein in PROSITE PS00022, EGF_1, 8 hits PS01186, EGF_2, 6 hits PS50026, EGF_3, 4 hits |
s (2+)i Sequence
Sequence statusi: Complete.
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show allAlign All
Isoform B (identifier: O61307-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MNPYEYESTL DCRDVGGGPT PAHAHPHAQG RTLPMSGHGR PTTDLGPVHG
60 70 80 90 100
SQTLQHQNQQ NLQAAQAAAQ SSHYDYEYQH LAHRPPDTAN NTAQRTHGRQ
110 120 130 140 150
GFLLEGVTPT APPDVPPRNP TMSRMQNGRL TVNNPNDADF EPSCLVRTPS
160 170 180 190 200
GNVYIPSGNL NINKGSPIDF KSGSACSTPT KDTLKGYERS TQGCMGPVLP
210 220 230 240 250
QRSVMNGLPA HHYSAPMNFR KDLVARCSSP WFGIGSISVL FAFVVMLILL
260 270 280 290 300
TTTGVIKWNQ SPPCSVLVGN EASEVTAAKS TNTDLSKLHN SSVRAKNGQG
310 320 330 340 350
IGLAQGQSGL GAAGVGSGGG SSAATVTTAT SNSGTAQGLQ STSASAEATS
360 370 380 390 400
SAATSSSQSS LTPSLSSSLA NANNGGARTF PARSFPPDGT TFGQITLGQK
410 420 430 440 450
LTKEIQPYSY WNMQFYQSEP AYVKFDYTIP RGASIGVYGR RNALPTHTQY
460 470 480 490 500
HFKEVLSGFS ASTRTARAAH LSITREVTRY MEPGHWFVSL YNDDGDVQEL
510 520 530 540 550
TFYAAVAEDM TQNCPNGCSG NGQCLLGHCQ CNPGFGGDDC SESVCPVLCS
560 570 580 590 600
QHGEYTNGEC ICNPGWKGKE CSLRHDECEV ADCSGHGHCV SGKCQCMRGY
610 620 630 640 650
KGKFCEEVDC PHPNCSGHGF CADGTCICKK GWKGPDCATM DQDALQCLPD
660 670 680 690 700
CSGHGTFDLD TQTCTCEAKW SGDDCSKELC DLDCGQHGRC EGDACACDPE
710 720 730 740 750
WGGEYCNTRL CDVRCNEHGQ CKNGTCLCVT GWNGKHCTIE GCPNSCAGHG
760 770 780 790 800
QCRVSGEGQW ECRCYEGWDG PDCGIALELN CGDSKDNDKD GLVDCEDPEC
810 820 830 840 850
CASHVCKTSQ LCVSAPKPID VLLRKQPPAI TASFFERMKF LIDESSLQNY
860 870 880 890 900
AKLETFNESR SAVIRGRVVT SLGMGLVGVR VSTTTLLEGF TLTRDDGWFD
910 920 930 940 950
LMVNGGGAVT LQFGRAPFRP QSRIVQVPWN EVVIIDLVVM SMSEEKGLAV
960 970 980 990 1000
TTTHTCFAHD YDLMKPVVLA SWKHGFQGAC PDRSAILAES QVIQESLQIP
1010 1020 1030 1040 1050
GTGLNLVYHS SRAAGYLSTI KLQLTPDVIP TSLHLIHLRI TIEGILFERI
1060 1070 1080 1090 1100
FEADPGIKFT YAWNRLNIYR QRVYGVTTAV VKVGYQYTDC TDIVWDIQTT
1110 1120 1130 1140 1150
KLSGHDMSIS EVGGWNLDIH HRYNFHEGIL QKGDGSNIYL RNKPRIILTT
1160 1170 1180 1190 1200
MGDGHQRPLE CPDCDGQATK QRLLAPVALA AAPDGSLFVG DFNYIRRIMT
1210 1220 1230 1240 1250
DGSIRTVVKL NATRVSYRYH MALSPLDGTL YVSDPESHQI IRVRDTNDYS
1260 1270 1280 1290 1300
QPELNWEAVV GSGERCLPGD EAHCGDGALA KDAKLAYPKG IAISSDNILY
1310 1320 1330 1340 1350
FADGTNIRMV DRDGIVSTLI GNHMHKSHWK PIPCEGTLKL EEMHLRWPTE
1360 1370 1380 1390 1400
LAVSPMDNTL HIIDDHMILR MTPDGRVRVI SGRPLHCATA STAYDTDLAT
1410 1420 1430 1440 1450
HATLVMPQSI AFGPLGELYV AESDSQRINR VRVIGTDGRI APFAGAESKC
1460 1470 1480 1490 1500
NCLERGCDCF EAEHYLATSA KFNTIAALAV TPDSHVHIAD QANYRIRSVM
1510 1520 1530 1540 1550
SSIPEASPSR EYEIYAPDMQ EIYIFNRFGQ HVSTRNILTG ETTYVFTYNV
1560 1570 1580 1590 1600
NTSNGKLSTV TDAAGNKVFL LRDYTSQVNS IENTKGQKCR LRMTRMKMLH
1610 1620 1630 1640 1650
ELSTPDNYNV TYEYHGPTGL LRTKLDSTGR SYVYNYDEFG RLTSAVTPTG
1660 1670 1680 1690 1700
RVIELSFDLS VKGAQVKVSE NAQKEMSLLI QGATVIVRNG AAESRTTVDM
1710 1720 1730 1740 1750
DGSTTSITPW GHNLQMEVAP YTILAEQSPL LGESYPVPAK QRTEIAGDLA
1760 1770 1780 1790 1800
NRFEWRYFVR RQQPLQAGKQ SKGPPRPVTE VGRKLRVNGD NVLTLEYDRE
1810 1820 1830 1840 1850
TQSVVVMVDD KQELLNVTYD RTSRPISFRP QSGDYADVDL EYDRFGRLVS
1860 1870 1880 1890 1900
WKWGVLQEAY SFDRNGRLNE IKYGDGSTMV YAFKDMFGSL PLKVTTPRRS
1910 1920 1930 1940 1950
DYLLQYDDAG ALQSLTTPRG HIHAFSLQTS LGFFKYQYYS PINRHPFEIL
1960 1970 1980 1990 2000
YNDEGQILAK IHPHQSGKVA FVHDTAGRLE TILAGLSSTH YTYQDTTSLV
2010 2020 2030 2040 2050
KSVEVQEPGF ELRREFKYHA GILKDEKLRF GSKNSLASAR YKYAYDGNAR
2060 2070 2080 2090 2100
LSGIEMAIDD KELPTTRYKY SQNLGQLEVV QDLKITRNAF NRTVIQDSAK
2110 2120 2130 2140 2150
QFFAIVDYDQ HGRVKSVLMN VKNIDVFRLE LDYDLRNRIK SQKTTFGRST
2160 2170 2180 2190 2200
AFDKINYNAD GHVVEVLGTN NWKYLFDENG NTVGVVDQGE KFNLGYDIGD
2210 2220 2230 2240 2250
RVIKVGDVEF NNYDARGFVV KRGEQKYRYN NRGQLIHSFE RERFQSWYYY
2260 2270 2280 2290 2300
DDRSRLVAWH DNKGNTTQYY YANPRTPHLV THVHFPKISR TMKLFYDDRD
2310 2320 2330 2340 2350
MLIALEHEDQ RYYVATDQNG SPLAFFDQNG SIVKEMKRTP FGRIIKDTKP
2360 2370 2380 2390 2400
EFFVPIDFHG GLIDPHTKLV YTEQRQYDPH VGQWMTPLWE TLATEMSHPT
2410 2420 2430 2440 2450
DVFIYRYHNN DPINPNKPQN YMIDLDSWLQ LFGYDLNNMQ SSRYTKLAQY
2460 2470 2480 2490 2500
TPQASIKSNT LAPDFGVISG LECIVEKTSE KFSDFDFVPK PLLKMEPKMR
2510 2520 2530 2540 2550
NLLPRVSYRR GVFGEGVLLS RIGGRALVSV VDGSNSVVQD VVSSVFNNSY
2560 2570 2580 2590 2600
FLDLHFSIHD QDVFYFVKDN VLKLRDDNEE LRRLGGMFNI STHEISDHGG
2610 2620 2630 2640 2650
SAAKELRLHG PDAVVIIKYG VDPEQERHRI LKHAHKRAVE RAWELEKQLV
2660 2670 2680 2690 2700
AAGFQGRGDW TEEEKEELVQ HGDVDGWNGI DIHSIHKYPQ LADDPGNVAF
2710 2720 2730
QRDAKRKRRK TGSSHRSASN RRQLKFGELS A
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketM9PGF7 | M9PGF7_DROME | Tenascin major, isoform E | Ten-m 2017, 5301, BcDNA:AT25108, CG11452, CT16449 | 3,349 | Annotation score: |
Sequence cautioni
The sequence CAA51678 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 22 | A → G in AAB88281 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 22 | A → G in AAC05080 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 37 | G → S in AAB88281 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 37 | G → S in AAC05080 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 65 | A → V in AAB88281 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 89 | A → V in AAB88281 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 1837 | D → Y in CAA51678 (PubMed:8070401).Curated | 1 | |
Sequence conflicti | 2099 | A → G in AAB88281 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 2099 | A → G in AAC05080 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 2315 | A → T in AAB88281 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 2495 | M → T in CAA51678 (PubMed:8070401).Curated | 1 | |
Sequence conflicti | 2710 | K → R in AAB88281 (PubMed:9373139).Curated | 1 | |
Sequence conflicti | 2710 | K → R in AAC05080 (PubMed:9373139).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_054459 | 375 | G → GGRAMSTRLSVRGAGERGRR HRRSLNEEQGEDDVATDGTF SDLITNESLNQQAAEKYLAT TLAKSPTDVHGSGNKTLPRM DGVYGTQRSEDTPDTSYDYV YEDEVEPETTPSLIRRTKTG QQFGKSLNSNLRSAAKTLVN KRRKYDHGTVEAEHIKHEEE EEEDEQKLERHEAIGMATEL TTESETSTLPAVIDDDNQSD NSSSGPTPETTVRSDTDDIV EINTPPSQTAQRTFAAVSHQ PAIEHDFQIKGTDAGGLQTE KPATDDINNERDLADNYEVD SKEPTSPGTPPQGKVSQQTG KASLQSLQSESDLMMNDASH YEDIDIVKLDGLTISHEEEI YKTADKENMAPKNQPSQHID RSQNEVLKGHQQGDEKQPQL EPLKPYVSERVDLPGKRIFL NLTIATDEGSDSVYTLHVEV PTGGGPHFIKEVLTHEKPTA QADSCVPEPPPRMPDCPCSC LPPPAPIYLDDTVDIDSAPP AKTVTTSTISAPINPFHSEE EDDEDGVRDEEQTPSSSTAT NLPSTEIDNHIAAFTEPAVG AGGVPFACPDVMPVLILE in isoform D. Curated | 1 | |
Alternative sequenceiVSP_054460 | 858 | E → ESIFWNYFNA in isoform D. Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X73154 mRNA Translation: CAA51678.1 Different initiation. AF008227, AF008224, AF008226 Genomic DNA Translation: AAC05080.1 AF008228 mRNA Translation: AAB88281.1 AE014296 Genomic DNA Translation: AAF51824.2 AE014296 Genomic DNA Translation: ABW08579.2 |
RefSeqi | NP_001097661.2, NM_001104191.3 [O61307-2] NP_524215.2, NM_079491.3 [O61307-1] |
Genome annotation databases
EnsemblMetazoai | FBtr0078509; FBpp0078161; FBgn0004449 [O61307-1] FBtr0306107; FBpp0297244; FBgn0004449 [O61307-2] |
GeneIDi | 40464 |
KEGGi | dme:Dmel_CG5723 |
UCSCi | CG5723-RB, d. melanogaster CG5723-RC, d. melanogaster |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | X73154 mRNA Translation: CAA51678.1 Different initiation. AF008227, AF008224, AF008226 Genomic DNA Translation: AAC05080.1 AF008228 mRNA Translation: AAB88281.1 AE014296 Genomic DNA Translation: AAF51824.2 AE014296 Genomic DNA Translation: ABW08579.2 |
RefSeqi | NP_001097661.2, NM_001104191.3 [O61307-2] NP_524215.2, NM_079491.3 [O61307-1] |
3D structure databases
SMRi | O61307 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 65699, 9 interactors |
IntActi | O61307, 705 interactors |
STRINGi | 7227.FBpp0297244 |
PTM databases
iPTMneti | O61307 |
Proteomic databases
PaxDbi | O61307 |
PeptideAtlasi | O61307 |
PRIDEi | O61307 |
Genome annotation databases
EnsemblMetazoai | FBtr0078509; FBpp0078161; FBgn0004449 [O61307-1] FBtr0306107; FBpp0297244; FBgn0004449 [O61307-2] |
GeneIDi | 40464 |
KEGGi | dme:Dmel_CG5723 |
UCSCi | CG5723-RB, d. melanogaster CG5723-RC, d. melanogaster |
Organism-specific databases
CTDi | 40464 |
FlyBasei | FBgn0004449, Ten-m |
Phylogenomic databases
eggNOGi | KOG1225, Eukaryota KOG4659, Eukaryota |
GeneTreei | ENSGT01010000222317 |
HOGENOMi | CLU_000229_1_0_1 |
InParanoidi | O61307 |
OMAi | AHYKYAY |
Miscellaneous databases
BioGRID-ORCSi | 40464, 0 hits in 3 CRISPR screens |
ChiTaRSi | Ten-m, fly |
GenomeRNAii | 40464 |
PROi | PR:O61307 |
Gene expression databases
Bgeei | FBgn0004449, Expressed in embryonic/larval hemocyte (Drosophila) and 42 other tissues |
ExpressionAtlasi | O61307, baseline and differential |
Genevisiblei | O61307, DM |
Family and domain databases
Gene3Di | 2.120.10.30, 2 hits 2.60.120.260, 1 hit |
InterProi | View protein in InterPro IPR011042, 6-blade_b-propeller_TolB-like IPR008969, CarboxyPept-like_regulatory IPR000742, EGF-like_dom IPR008979, Galactose-bd-like_sf IPR031325, RHS_repeat IPR028916, Tox-GHH_dom IPR006530, YD |
Pfami | View protein in Pfam PF05593, RHS_repeat, 1 hit PF15636, Tox-GHH, 1 hit |
SMARTi | View protein in SMART SM00181, EGF, 8 hits |
SUPFAMi | SSF49464, SSF49464, 1 hit |
TIGRFAMsi | TIGR01643, YD_repeat_2x, 1 hit |
PROSITEi | View protein in PROSITE PS00022, EGF_1, 8 hits PS01186, EGF_2, 6 hits PS50026, EGF_3, 4 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | TENM_DROME | |
Accessioni | O61307Primary (citable) accession number: O61307 Secondary accession number(s): A8JNW8 Q9VNU6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 6, 2013 |
Last sequence update: | February 6, 2013 | |
Last modified: | December 2, 2020 | |
This is version 146 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Drosophila annotation project |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Drosophila
Drosophila: entries, gene names and cross-references to FlyBase - SIMILARITY comments
Index of protein domains and families