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UniProtKB - O61059 (O61059_LEIME)
Protein
Submitted name:
Glucose transporter
Gene
LmGT2
Organism
Leishmania mexicana
Status
Functioni
GO - Molecular functioni
- carbohydrate transmembrane transporter activity Source: InterPro
Keywordsi
Biological process | Sugar transportImportedARBA annotation, Transport |
Protein family/group databases
TCDBi | 2.A.1.1.77, the major facilitator superfamily (mfs) |
Names & Taxonomyi
Protein namesi | Submitted name: Glucose transporterImported |
Gene namesi | Name:LmGT2Imported |
Organismi | Leishmania mexicanaImported |
Taxonomic identifieri | 5665 [NCBI] |
Taxonomic lineagei | Eukaryota › Discoba › Euglenozoa › Kinetoplastea › Metakinetoplastina › Trypanosomatida › Trypanosomatidae › Leishmaniinae › Leishmania › |
Organism-specific databases
VEuPathDBi | TriTrypDB:LmxM.36.6290 |
Subcellular locationi
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 158 – 179 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 186 – 206 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 212 – 236 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 248 – 268 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 288 – 308 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 341 – 363 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 375 – 397 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 404 – 425 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 437 – 462 | HelicalSequence analysisAdd BLAST | 26 | |
Transmembranei | 474 – 496 | HelicalSequence analysisAdd BLAST | 23 | |
Transmembranei | 516 – 537 | HelicalSequence analysisAdd BLAST | 22 |
Keywords - Cellular componenti
MembraneStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 45 – 538 | MFSInterPro annotationAdd BLAST | 494 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 21 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 541 – 567 | DisorderedSequence analysisAdd BLAST | 27 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]UniRule annotationARBA annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
OMAi | CCAVYAS |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 2 hits |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O61059-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDKLEANGR SSRSEKEPIH DVITKNVMED EDDAPPFLSA SNARVTLVQA
60 70 80 90 100
IGGCLNGYSI GFVGVYSTLF GYSTNCANFR SERGCTTAPN ADCQWFANAT
110 120 130 140 150
GTSYCGWPEI TCRRTYTYSS VAEMPGAIAQ CEADSRCRWS YSAKECQNPS
160 170 180 190 200
GYSSSESGIF AGSMIAGCLI GSVFAGPLAS TIGARLSFLL VGLVGVVSSV
210 220 230 240 250
MCHVSASENE FWVLVVGRFV IGLFVGVIGV ACPVYTDQNA HPKWKRTIGV
260 270 280 290 300
MFQVFTTLGI FIAAAVGLAL GQSTYFDRNK DQMVMARMQG LCAFSTLFSL
310 320 330 340 350
LTILLGIVMS ESRAKFGGDD EEGGIELDPN EYSYVEMVPR LLMGAVMAGT
360 370 380 390 400
LQLTGINAVM NYAPAIMGSL GLAPLVGNFV VMLWNFVTTL ASIPLSYVFT
410 420 430 440 450
MRQLFLFGSL FTSSMCLFMC GIPVYPGVSK KTEVKNGVAI TGILLFILGF
460 470 480 490 500
EVCVGPCYFV LTQDMFPLSF RPRGASFTQV AQFIFNLIIN VCYPIATEHI
510 520 530 540 550
SGGPSGNQDK GQAVAFIFFG CLGMICFIIQ VFFLHPWDEK RDGKKRPATP
560
AGGKRELSSS LSGNRAE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF039221 Genomic DNA Translation: AAC70907.2 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF039221 Genomic DNA Translation: AAC70907.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Chemistry databases
ChEMBLi | CHEMBL3431938 |
Protein family/group databases
TCDBi | 2.A.1.1.77, the major facilitator superfamily (mfs) |
Organism-specific databases
VEuPathDBi | TriTrypDB:LmxM.36.6290 |
Phylogenomic databases
OMAi | CCAVYAS |
Family and domain databases
Gene3Di | 1.20.1250.20, 2 hits |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR045262, STP/PLT_plant IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
PANTHERi | PTHR23500, PTHR23500, 1 hit |
Pfami | View protein in Pfam PF00083, Sugar_tr, 2 hits |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | O61059_LEIME | |
Accessioni | O61059Primary (citable) accession number: O61059 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | August 1, 1998 |
Last sequence update: | January 11, 2011 | |
Last modified: | May 25, 2022 | |
This is version 95 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |