RNASEH1

Functionⁱ

Endonuclease that specifically degrades the RNA of RNA-DNA hybrids (PubMed:10497183). Plays a role in RNA polymerase II (RNAp II) transcription termination by degrading R-loop RNA-DNA hybrid formation at G-rich pause sites located downstream of the poly(A) site and behind the elongating RNAp II (PubMed:21700224).2 Publications

Catalytic activityⁱ

Endonucleolytic cleavage to 5'-phosphomonoester.PROSITE-ProRule annotation

Cofactorⁱ

Mg²⁺Note: Binds 1 Mg²⁺ ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.

Activity regulationⁱ

In the presence of magnesium, manganese is inhibitory.

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	145	Magnesium 1PROSITE-ProRule annotation	1
Metal bindingⁱ	145	Magnesium 2PROSITE-ProRule annotation	1
Metal bindingⁱ	186	Magnesium 1PROSITE-ProRule annotation	1
Metal bindingⁱ	210	Magnesium 1PROSITE-ProRule annotation	1
Metal bindingⁱ	274	Magnesium 2PROSITE-ProRule annotation	1

GO - Molecular functionⁱ

magnesium ion binding Source: InterPro
nucleic acid binding
Source: ProtInc
Traceable author statementⁱ
- 9799596
ribonuclease activity
Source: ProtInc
Traceable author statementⁱ
- 9799596
RNA binding
Source: ProtInc
Traceable author statementⁱ
- 9799596
RNA-DNA hybrid ribonuclease activity
Source: UniProtKB
Inferred from direct assayⁱ
- 21700224

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

DNA replication, removal of RNA primer
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
RNA catabolic process
Source: ProtInc
Traceable author statementⁱ
- 9799596
RNA phosphodiester bond hydrolysis, endonucleolytic
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Endonuclease, Hydrolase, Nuclease
Ligand	Magnesium, Metal-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Ribonuclease H1 (EC:3.1.26.4) Short name: RNase H1 Alternative name(s): Ribonuclease H type II
Gene namesⁱ	Name:RNASEH1 Synonyms:RNH1
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 2

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000171865.9
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:18466 RNASEH1
MIMⁱ	604123 gene
neXtProtⁱ	NX_O60930

Keywords - Cellular componentⁱ

Cytoplasm

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2 (PEOB2)1 Publication

The disease is caused by mutations affecting the gene represented in this entry.

Disease descriptionA form of progressive external ophthalmoplegia, a mitochondrial myopathy characterized by progressive paralysis of the levator palpebrae, orbicularis oculi, and extraocular muscles. PEOB2 patients manifest exercise intolerance, muscle weakness, and signs and symptoms of spinocerebellar ataxia, such as impaired gait and dysarthria. Some patients may have respiratory insufficiency.

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱVAR_074561	142	V → I in PEOB2; has partial residual endonuclease activity. 1 PublicationCorresponds to variant dbSNP:rs766294940EnsemblClinVar.		1
Natural variantⁱVAR_074562	185	A → V in PEOB2; has partial residual endonuclease activity. 1 PublicationCorresponds to variant dbSNP:rs1057517675Ensembl.		1

Keywords - Diseaseⁱ

Disease mutation, Primary mitochondrial disease, Progressive external ophthalmoplegia

Organism-specific databases

DisGeNET More...DisGeNETⁱ	246243
MalaCards human disease database More...MalaCardsⁱ	RNASEH1
MIMⁱ	616479 phenotype
Open Targets More...OpenTargetsⁱ	ENSG00000171865
Orphanetⁱ	329336 Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy
PharmGKBⁱ	PA38543

Chemistry databases

ChEMBLⁱ	CHEMBL5893

ChEMBLⁱ

CHEMBL5893

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000195433	1 – 286	Ribonuclease H1Add BLAST		286

Proteomic databases

EPDⁱ	O60930
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O60930
PaxDbⁱ	O60930
PeptideAtlas More...PeptideAtlasⁱ	O60930
PRIDEⁱ	O60930
ProteomicsDBⁱ	49675

PTM databases

iPTMnetⁱ	O60930
PhosphoSitePlusⁱ	O60930

Expressionⁱ

Tissue specificityⁱ

Ubiquitous.

Gene expression databases

Bgeeⁱ	ENSG00000171865 Expressed in 235 organ(s), highest expression level in secondary oocyte
CleanExⁱ	HS_RNASEH1 HS_RNH1
ExpressionAtlasⁱ	O60930 baseline and differential
Genevisibleⁱ	O60930 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	HPA043037

HPAⁱ

HPA043037

Interactionⁱ

Subunit structureⁱ

Monomer.Curated

Protein-protein interaction databases

BioGridⁱ	128882, 13 interactors
IntActⁱ	O60930, 10 interactors
Molecular INTeraction database More...MINTⁱ	O60930
STRINGⁱ	9606.ENSP00000313350

Chemistry databases

BindingDBⁱ

O60930

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Beta strandⁱ	28 – 36	Combined sources	9
Beta strandⁱ	38 – 42	Combined sources	5
Helixⁱ	43 – 50	Combined sources	8
Beta strandⁱ	57 – 63	Combined sources	7
Helixⁱ	64 – 72	Combined sources	9
Beta strandⁱ	139 – 149	Combined sources	11
Turnⁱ	150 – 152	Combined sources	3
Beta strandⁱ	153 – 155	Combined sources	3
Beta strandⁱ	157 – 163	Combined sources	7
Beta strandⁱ	172 – 175	Combined sources	4
Helixⁱ	182 – 199	Combined sources	18
Beta strandⁱ	204 – 210	Combined sources	7
Helixⁱ	212 – 219	Combined sources	8
Helixⁱ	221 – 226	Combined sources	6
Turnⁱ	227 – 229	Combined sources	3
Beta strandⁱ	235 – 237	Combined sources	3
Helixⁱ	241 – 251	Combined sources	11
Beta strandⁱ	255 – 260	Combined sources	6
Beta strandⁱ	263 – 265	Combined sources	3
Helixⁱ	268 – 281	Combined sources	14

Show more details

3D structure databases

ProteinModelPortalⁱ	O60930
SMRⁱ	O60930
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	O60930

EvolutionaryTraceⁱ

O60930

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	136 – 282	RNase HPROSITE-ProRule annotationAdd BLAST		147

Sequence similaritiesⁱ

Belongs to the RNase H family.Curated

Phylogenomic databases

eggNOGⁱ	KOG3752 Eukaryota COG0328 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000003466
HOGENOMⁱ	HOG000040465
HOVERGENⁱ	HBG002135
InParanoidⁱ	O60930
KEGG Orthology (KO) More...KOⁱ	K03469
OMAⁱ	ELWYGLY
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0RCI
PhylomeDBⁱ	O60930
TreeFamⁱ	TF313356

Family and domain databases

Gene3Dⁱ	3.30.420.10, 1 hit 3.40.970.10, 1 hit
InterProⁱ	View protein in InterPro IPR009027 Ribosomal_L9/RNase_H1_N IPR017067 RNase_H1_euk IPR011320 RNase_H1_N IPR037056 RNase_H1_N_sf IPR012337 RNaseH-like_sf IPR002156 RNaseH_domain IPR036397 RNaseH_sf
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF01693 Cauli_VI, 1 hit PF00075 RNase_H, 1 hit
PIRSFⁱ	PIRSF036852 Ribonuclease_H1_euk, 1 hit
SUPFAMⁱ	SSF53098 SSF53098, 1 hit SSF55658 SSF55658, 1 hit
PROSITEⁱ	View protein in PROSITE PS50879 RNASE_H, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show all Align All

O60930-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSWLLFLAHR VALAALPCRR GSRGFGMFYA VRRGRKTGVF LTWNECRAQV 
        60         70         80         90        100
DRFPAARFKK FATEDEAWAF VRKSASPEVS EGHENQHGQE SEAKASKRLR 
       110        120        130        140        150
EPLDGDGHES AEPYAKHMKP SVEPAPPVSR DTFSYMGDFV VVYTDGCCSS 
       160        170        180        190        200
NGRRRPRAGI GVYWGPGHPL NVGIRLPGRQ TNQRAEIHAA CKAIEQAKTQ 
       210        220        230        240        250
NINKLVLYTD SMFTINGITN WVQGWKKNGW KTSAGKEVIN KEDFVALERL 
       260        270        280 
TQGMDIQWMH VPGHSGFIGN EEADRLAREG AKQSED

Length:286

Mass (Da):32,064

Last modified:April 27, 2001 - v2

Checksum:ⁱ400FE04E7E85CA6A

GO

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

F8WBP0	F8WBP0_HUMAN	Ribonuclease H1 Ribonuclease H1	RNASEH1	43	Annotation score:
F8WD93	F8WD93_HUMAN	Ribonuclease H1 Ribonuclease H1	RNASEH1	43	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Length
Sequence conflictⁱ	24	G → R in AAV38476 (Ref. 5) Curated	1
Sequence conflictⁱ	33	R → K in CAG46619 (Ref. 4) Curated	1
Sequence conflictⁱ	68	W → R in AAV38476 (Ref. 5) Curated	1
Sequence conflictⁱ	89	Q → R in CAA11835 (PubMed:9894807).Curated	1
Sequence conflictⁱ	136	M → I in CAG46619 (Ref. 4) Curated	1
Sequence conflictⁱ	223	Q → R in CAA11835 (PubMed:9894807).Curated	1

Natural variant

Feature key	Position(s)	DescriptionActions	Length
Natural variantⁱVAR_023469	4	L → F2 PublicationsCorresponds to variant dbSNP:rs1136545Ensembl.	1
Natural variantⁱVAR_074561	142	V → I in PEOB2; has partial residual endonuclease activity. 1 PublicationCorresponds to variant dbSNP:rs766294940EnsemblClinVar.	1
Natural variantⁱVAR_074562	185	A → V in PEOB2; has partial residual endonuclease activity. 1 PublicationCorresponds to variant dbSNP:rs1057517675Ensembl.	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF048995 mRNA Translation: AAC78564.1 AF048994 mRNA Translation: AAC78563.1 AF039652 mRNA Translation: AAC09261.1 AJ224117 mRNA Translation: CAA11835.1 CR541820 mRNA Translation: CAG46619.1 BT019670 mRNA Translation: AAV38476.1 AK075490 mRNA Translation: BAG52156.1 AC108488 Genomic DNA Translation: AAX82026.1 CH471053 Genomic DNA Translation: EAX01061.1 BC002973 mRNA Translation: AAH02973.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS1647.1
NCBI Reference Sequences More...RefSeqⁱ	NP_002927.2, NM_002936.4
UniGeneⁱ	Hs.568006

Genome annotation databases

Ensemblⁱ	ENST00000315212; ENSP00000313350; ENSG00000171865
GeneIDⁱ	246243
KEGGⁱ	hsa:246243
UCSC genome browser More...UCSCⁱ	uc002qxt.5 human

Keywords - Coding sequence diversityⁱ

Polymorphism

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O60930	Ribonuclease H1		HUMAN		286	UniRef100_O60930
cDNA FLJ39594 fis, clone SKNSH2001875, highly similar to Ribonuclease H1		HUMAN		169
Ribonuclease H1		HUMAN		43
UPI0000207FD6		HUMAN		260

Protein	Similar proteins		Species	Score	Length	Source
O60930	Ribonuclease H1		HUMAN		286	UniRef90_O60930
Ribonuclease H1		CALJA		290
Ribonuclease H1		RHIRO		289
Ribonuclease H1		SAIBB		288
Ribonuclease H1		Cebus capucinus imitator		288
+40

Protein	Similar proteins		Species	Score	Length	Source
O60930	Ribonuclease H1		MOUSE		285	UniRef50_O60930
Ribonuclease H1		RAT		285
Ribonuclease H1		HUMAN		286
Ribonuclease H1		CALJA		290
Ribonuclease H1		RHIRO		289
+103

Cross-referencesⁱ

Web resourcesⁱ

Wikipedia

RNase H entry

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AF048995 mRNA Translation: AAC78564.1 AF048994 mRNA Translation: AAC78563.1 AF039652 mRNA Translation: AAC09261.1 AJ224117 mRNA Translation: CAA11835.1 CR541820 mRNA Translation: CAG46619.1 BT019670 mRNA Translation: AAV38476.1 AK075490 mRNA Translation: BAG52156.1 AC108488 Genomic DNA Translation: AAX82026.1 CH471053 Genomic DNA Translation: EAX01061.1 BC002973 mRNA Translation: AAH02973.1
CCDSⁱ	CCDS1647.1
RefSeqⁱ	NP_002927.2, NM_002936.4
UniGeneⁱ	Hs.568006

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2QK9	X-ray	2.55	A	136-286	[»]
	2QKB	X-ray	2.40	A/B	136-286	[»]
	2QKK	X-ray	3.20	A/B/E/F/I/J/M/N/R/S/W	136-286	[»]
	3BSU	X-ray	2.10	A/B/C/F/G/H	27-76	[»]
ProteinModelPortalⁱ	O60930
SMRⁱ	O60930
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	128882, 13 interactors
IntActⁱ	O60930, 10 interactors
MINTⁱ	O60930
STRINGⁱ	9606.ENSP00000313350

Chemistry databases

BindingDBⁱ	O60930
ChEMBLⁱ	CHEMBL5893

PTM databases

iPTMnetⁱ	O60930
PhosphoSitePlusⁱ	O60930

Proteomic databases

EPDⁱ	O60930
MaxQBⁱ	O60930
PaxDbⁱ	O60930
PeptideAtlasⁱ	O60930
PRIDEⁱ	O60930
ProteomicsDBⁱ	49675

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	246243
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENST00000315212; ENSP00000313350; ENSG00000171865
GeneIDⁱ	246243
KEGGⁱ	hsa:246243
UCSCⁱ	uc002qxt.5 human

Organism-specific databases

CTDⁱ	246243
DisGeNETⁱ	246243
EuPathDBⁱ	HostDB:ENSG00000171865.9
GeneCardsⁱ	RNASEH1
H-InvDBⁱ	HIX0039191
HGNCⁱ	HGNC:18466 RNASEH1
HPAⁱ	HPA043037
MalaCardsⁱ	RNASEH1
MIMⁱ	604123 gene 616479 phenotype
neXtProtⁱ	NX_O60930
OpenTargetsⁱ	ENSG00000171865
Orphanetⁱ	329336 Adult-onset chronic progressive external ophthalmoplegia with mitochondrial myopathy
PharmGKBⁱ	PA38543
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG3752 Eukaryota COG0328 LUCA
GeneTreeⁱ	ENSGT00390000003466
HOGENOMⁱ	HOG000040465
HOVERGENⁱ	HBG002135
InParanoidⁱ	O60930
KOⁱ	K03469
OMAⁱ	ELWYGLY
OrthoDBⁱ	EOG091G0RCI
PhylomeDBⁱ	O60930
TreeFamⁱ	TF313356

Miscellaneous databases

ChiTaRSⁱ	RNASEH1 human
EvolutionaryTraceⁱ	O60930
GeneWikiⁱ	RNASEH1
GenomeRNAiⁱ	246243
Protein Ontology More...PROⁱ	PR:O60930
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000171865 Expressed in 235 organ(s), highest expression level in secondary oocyte
CleanExⁱ	HS_RNASEH1 HS_RNH1
ExpressionAtlasⁱ	O60930 baseline and differential
Genevisibleⁱ	O60930 HS

Family and domain databases

Gene3Dⁱ	3.30.420.10, 1 hit 3.40.970.10, 1 hit
InterProⁱ	View protein in InterPro IPR009027 Ribosomal_L9/RNase_H1_N IPR017067 RNase_H1_euk IPR011320 RNase_H1_N IPR037056 RNase_H1_N_sf IPR012337 RNaseH-like_sf IPR002156 RNaseH_domain IPR036397 RNaseH_sf
Pfamⁱ	View protein in Pfam PF01693 Cauli_VI, 1 hit PF00075 RNase_H, 1 hit
PIRSFⁱ	PIRSF036852 Ribonuclease_H1_euk, 1 hit
SUPFAMⁱ	SSF53098 SSF53098, 1 hit SSF55658 SSF55658, 1 hit
PROSITEⁱ	View protein in PROSITE PS50879 RNASE_H, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	RNH1_HUMAN
Accessionⁱ	O60930Primary (citable) accession number: O60930 Secondary accession number(s): B3KQU4 , O60523, O60857, Q57Z93, Q5U0C1, Q6FHD4
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	April 27, 2001
	Last sequence update:	April 27, 2001
	Last modified:	November 7, 2018
	This is version 173 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Human chromosome 2
Human chromosome 2: entries, gene names and cross-references to MIM
Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

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UniProtKB - O60930 (RNH1_HUMAN)

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Ribonuclease H1

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

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Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

Organism-specific databases

Chemistry databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

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<p>This subsection of the <a href="http://www.uniprot.org/manual/cross_references_section">Cross-references</a> section provides links to various web resources that are relevant for a specific protein.<p><a href='/help/web_resource' target='_top'>More...</a></p>Web resourcesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

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Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Web resourcesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ