CTSV

Functionⁱ

Cysteine protease. May have an important role in corneal physiology.2 Publications

Catalytic activityⁱ

The recombinant enzyme hydrolyzes proteins (serum albumin, collagen) and synthetic substrates (Z-Phe-Arg-NHMec > Z-Leu-Arg-NHMec > Z-Val-Arg-NHMec).1 Publication

Sites

Feature key	Position(s)	DescriptionActions	Length
Active siteⁱ	138	1 Publication	1
Active siteⁱ	277	1 Publication	1
Active siteⁱ	301	1 Publication	1

GO - Molecular functionⁱ

aminopeptidase activity Source: Ensembl
cysteine-type endopeptidase activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
cysteine-type peptidase activity
Source: ProtInc
Traceable author statementⁱ
- 9563472
kininogen binding Source: Ensembl
peptide binding Source: Ensembl
protein-containing complex binding Source: Ensembl
serine-type endopeptidase activity Source: Reactome

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
autophagic cell death Source: Ensembl
cellular response to starvation Source: Ensembl
decidualization Source: Ensembl
extracellular matrix disassembly Source: Reactome
multicellular organism aging Source: Ensembl
nerve development Source: Ensembl
proteolysis involved in cellular protein catabolic process
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
regulation of keratinocyte differentiation Source: Reactome
response to glucocorticoid Source: Ensembl
response to glucose Source: Ensembl
response to gonadotropin Source: Ensembl
response to odorant Source: Ensembl
Sertoli cell differentiation Source: Ensembl
spermatogenesis Source: Ensembl

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Hydrolase, Protease, Thiol protease

Molecular function

Hydrolase, Protease, Thiol protease

Enzyme and pathway databases

BRENDAⁱ	3.4.22.43 2681
Reactomeⁱ	R-HSA-1236977 Endosomal/Vacuolar pathway R-HSA-1474228 Degradation of the extracellular matrix R-HSA-1592389 Activation of Matrix Metalloproteinases R-HSA-1679131 Trafficking and processing of endosomal TLR R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures R-HSA-2132295 MHC class II antigen presentation R-HSA-8939242 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
SABIO-RKⁱ	O60911

Protein family/group databases

MEROPS protease database More...MEROPSⁱ	I29.010

MEROPSⁱ

I29.010

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Cathepsin L2 (EC:3.4.22.43) Alternative name(s): Cathepsin U Cathepsin V
Gene namesⁱ	Name:CTSV Synonyms:CATL2, CTSL2, CTSU ORF Names:UNQ268/PRO305
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 9

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000136943.10
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:2538 CTSV
MIMⁱ	603308 gene
neXtProtⁱ	NX_O60911

Keywords - Cellular componentⁱ

Lysosome

Pathology & Biotechⁱ

Organism-specific databases

DisGeNET More...DisGeNETⁱ	1515
Open Targets More...OpenTargetsⁱ	ENSG00000136943
PharmGKBⁱ	PA27036

Chemistry databases

ChEMBLⁱ	CHEMBL3272
Drug and drug target database More...DrugBankⁱ	DB02869 3-amino-5-phenylpentane DB04451 4-Methylpiperazin-1-Yl Carbonyl Group
IUPHAR/BPS Guide to PHARMACOLOGY More...GuidetoPHARMACOLOGYⁱ	2352

Polymorphism and mutation databases

BioMutaⁱ	CTSV

BioMutaⁱ

CTSV

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Length
Signal peptideⁱ	1 – 17	Sequence analysisAdd BLAST	17
PropeptideⁱPRO_0000026277	18 – 113	Activation peptideAdd BLAST	96
ChainⁱPRO_0000026278	114 – 334	Cathepsin L2Add BLAST	221

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Disulfide bondⁱ	135 ↔ 178	Combined sources1 Publication
Disulfide bondⁱ	169 ↔ 211	Combined sources1 Publication
Glycosylationⁱ	221	N-linked (GlcNAc...) asparagine1 Publication	1
Disulfide bondⁱ	270 ↔ 323	Combined sources1 Publication
Glycosylationⁱ	292	N-linked (GlcNAc...) asparagine1 Publication	1

Keywords - PTMⁱ

Disulfide bond, Glycoprotein, Zymogen

Proteomic databases

EPDⁱ	O60911
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O60911
PaxDbⁱ	O60911
PeptideAtlas More...PeptideAtlasⁱ	O60911
PRIDEⁱ	O60911
ProteomicsDBⁱ	49669

PTM databases

iPTMnetⁱ	O60911
PhosphoSitePlusⁱ	O60911

Expressionⁱ

Tissue specificityⁱ

Predominantly expressed in the thymus and testis. Also expressed in corneal epithelium, and to a lesser extent in conjunctival epithelium and skin.3 Publications

Gene expression databases

Bgeeⁱ	ENSG00000136943 Expressed in 175 organ(s), highest expression level in hair follicle
CleanExⁱ	HS_CTSL2
ExpressionAtlasⁱ	O60911 baseline and differential
Genevisibleⁱ	O60911 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB017112

HPAⁱ

CAB017112

Interactionⁱ

GO - Molecular functionⁱ

kininogen binding Source: Ensembl

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	107895, 31 interactors
IntActⁱ	O60911, 15 interactors
Molecular INTeraction database More...MINTⁱ	O60911
STRINGⁱ	9606.ENSP00000259470

Chemistry databases

BindingDBⁱ

O60911

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	120 – 123	Combined sources	4
Helixⁱ	138 – 155	Combined sources	18
Helixⁱ	163 – 169	Combined sources	7
Helixⁱ	171 – 173	Combined sources	3
Helixⁱ	177 – 179	Combined sources	3
Helixⁱ	183 – 193	Combined sources	11
Beta strandⁱ	196 – 198	Combined sources	3
Turnⁱ	199 – 201	Combined sources	3
Helixⁱ	215 – 217	Combined sources	3
Beta strandⁱ	218 – 220	Combined sources	3
Beta strandⁱ	225 – 227	Combined sources	3
Helixⁱ	233 – 242	Combined sources	10
Beta strandⁱ	246 – 250	Combined sources	5
Helixⁱ	255 – 258	Combined sources	4
Beta strandⁱ	262 – 265	Combined sources	4
Beta strandⁱ	272 – 274	Combined sources	3
Beta strandⁱ	277 – 289	Combined sources	13
Beta strandⁱ	293 – 300	Combined sources	8
Beta strandⁱ	312 – 316	Combined sources	5
Beta strandⁱ	318 – 321	Combined sources	4
Helixⁱ	322 – 324	Combined sources	3
Turnⁱ	325 – 327	Combined sources	3
Beta strandⁱ	330 – 332	Combined sources	3

Show more details

3D structure databases

ProteinModelPortalⁱ	O60911
SMRⁱ	O60911
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	O60911

EvolutionaryTraceⁱ

O60911

Family & Domainsⁱ

Sequence similaritiesⁱ

Belongs to the peptidase C1 family.PROSITE-ProRule annotation

Keywords - Domainⁱ

Signal

Phylogenomic databases

eggNOGⁱ	KOG1543 Eukaryota COG4870 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00900000140823
HOGENOMⁱ	HOG000230774
HOVERGENⁱ	HBG011513
InParanoidⁱ	O60911
KEGG Orthology (KO) More...KOⁱ	K01375
OMAⁱ	FEGANSD
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AKT
PhylomeDBⁱ	O60911
TreeFamⁱ	TF313739

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd02248 Peptidase_C1A, 1 hit
InterProⁱ	View protein in InterPro IPR038765 Papain_like_cys_pep_sf IPR025661 Pept_asp_AS IPR000169 Pept_cys_AS IPR025660 Pept_his_AS IPR013128 Peptidase_C1A IPR000668 Peptidase_C1A_C IPR039417 Peptidase_C1A_papain-like IPR013201 Prot_inhib_I29
PANTHERⁱ	PTHR12411 PTHR12411, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF08246 Inhibitor_I29, 1 hit PF00112 Peptidase_C1, 1 hit
PRINTSⁱ	PR00705 PAPAIN
SMARTⁱ	View protein in SMART SM00848 Inhibitor_I29, 1 hit SM00645 Pept_C1, 1 hit
SUPFAMⁱ	SSF54001 SSF54001, 1 hit
PROSITEⁱ	View protein in PROSITE PS00640 THIOL_PROTEASE_ASN, 1 hit PS00139 THIOL_PROTEASE_CYS, 1 hit PS00639 THIOL_PROTEASE_HIS, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

O60911-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MNLSLVLAAF CLGIASAVPK FDQNLDTKWY QWKATHRRLY GANEEGWRRA 
        60         70         80         90        100
VWEKNMKMIE LHNGEYSQGK HGFTMAMNAF GDMTNEEFRQ MMGCFRNQKF 
       110        120        130        140        150
RKGKVFREPL FLDLPKSVDW RKKGYVTPVK NQKQCGSCWA FSATGALEGQ 
       160        170        180        190        200
MFRKTGKLVS LSEQNLVDCS RPQGNQGCNG GFMARAFQYV KENGGLDSEE 
       210        220        230        240        250
SYPYVAVDEI CKYRPENSVA NDTGFTVVAP GKEKALMKAV ATVGPISVAM 
       260        270        280        290        300
DAGHSSFQFY KSGIYFEPDC SSKNLDHGVL VVGYGFEGAN SNNSKYWLVK 
       310        320        330 
NSWGPEWGSN GYVKIAKDKN NHCGIATAAS YPNV

Length:334

Mass (Da):37,329

Last modified:December 1, 2000 - v2

Checksum:ⁱCD2DE51AC5F242C8

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	81	G → P in CAA75029 (PubMed:9563472).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Y14734 mRNA Translation: CAA75029.1 AB001928 mRNA Translation: BAA25909.1 AF070448 mRNA Translation: AAC23598.1 AB019534 Genomic DNA Translation: BAA34365.1 AY358641 mRNA Translation: AAQ89004.1 AL445670 Genomic DNA No translation available. BC023504 mRNA Translation: AAH23504.1 BC110512 mRNA Translation: AAI10513.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS6723.1
NCBI Reference Sequences More...RefSeqⁱ	NP_001188504.1, NM_001201575.1 NP_001324.2, NM_001333.3
UniGeneⁱ	Hs.610096

Genome annotation databases

Ensemblⁱ	ENST00000259470; ENSP00000259470; ENSG00000136943 ENST00000538255; ENSP00000445052; ENSG00000136943
GeneIDⁱ	1515
KEGGⁱ	hsa:1515
UCSC genome browser More...UCSCⁱ	uc004awt.4 human

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O60911	Cathepsin L2, isoform CRA_a		HUMAN		334	UniRef100_O60911

Protein	Similar proteins		Species	Score	Length	Source
O60911	Cathepsin L2, isoform CRA_a		HUMAN		334	UniRef90_O60911
Uncharacterized protein		NOMLE		335
CTSV isoform 1		PONAB		334
CTSV isoform 1		PANTR		334
Cathepsin V		GORGO		334
+11

Protein	Similar proteins		Species	Score	Length	Source
O60911	Crustapain		PANBO		323	UniRef50_O60911
Cathepsin L2, isoform CRA_a		HUMAN		334
Uncharacterized protein		NOMLE		335
CTSV isoform 1		PONAB		334
Uncharacterized protein		RHIRO		334
+260

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	Y14734 mRNA Translation: CAA75029.1 AB001928 mRNA Translation: BAA25909.1 AF070448 mRNA Translation: AAC23598.1 AB019534 Genomic DNA Translation: BAA34365.1 AY358641 mRNA Translation: AAQ89004.1 AL445670 Genomic DNA No translation available. BC023504 mRNA Translation: AAH23504.1 BC110512 mRNA Translation: AAI10513.1
CCDSⁱ	CCDS6723.1
RefSeqⁱ	NP_001188504.1, NM_001201575.1 NP_001324.2, NM_001333.3
UniGeneⁱ	Hs.610096

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	1FH0	X-ray	1.60	A/B	114-334	[»]
	3H6S	X-ray	2.22	A/B/C/D	114-334	[»]
	3KFQ	X-ray	1.99	A/B	114-334	[»]
ProteinModelPortalⁱ	O60911
SMRⁱ	O60911
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	107895, 31 interactors
IntActⁱ	O60911, 15 interactors
MINTⁱ	O60911
STRINGⁱ	9606.ENSP00000259470

Chemistry databases

BindingDBⁱ	O60911
ChEMBLⁱ	CHEMBL3272
DrugBankⁱ	DB02869 3-amino-5-phenylpentane DB04451 4-Methylpiperazin-1-Yl Carbonyl Group
GuidetoPHARMACOLOGYⁱ	2352

Protein family/group databases

MEROPSⁱ	I29.010

MEROPSⁱ

I29.010

PTM databases

iPTMnetⁱ	O60911
PhosphoSitePlusⁱ	O60911

Polymorphism and mutation databases

BioMutaⁱ	CTSV

BioMutaⁱ

CTSV

Proteomic databases

EPDⁱ	O60911
MaxQBⁱ	O60911
PaxDbⁱ	O60911
PeptideAtlasⁱ	O60911
PRIDEⁱ	O60911
ProteomicsDBⁱ	49669

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000259470; ENSP00000259470; ENSG00000136943 ENST00000538255; ENSP00000445052; ENSG00000136943
GeneIDⁱ	1515
KEGGⁱ	hsa:1515
UCSCⁱ	uc004awt.4 human

Organism-specific databases

CTDⁱ	1515
DisGeNETⁱ	1515
EuPathDBⁱ	HostDB:ENSG00000136943.10
GeneCardsⁱ	CTSV
HGNCⁱ	HGNC:2538 CTSV
HPAⁱ	CAB017112
MIMⁱ	603308 gene
neXtProtⁱ	NX_O60911
OpenTargetsⁱ	ENSG00000136943
PharmGKBⁱ	PA27036
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG1543 Eukaryota COG4870 LUCA
GeneTreeⁱ	ENSGT00900000140823
HOGENOMⁱ	HOG000230774
HOVERGENⁱ	HBG011513
InParanoidⁱ	O60911
KOⁱ	K01375
OMAⁱ	FEGANSD
OrthoDBⁱ	EOG091G0AKT
PhylomeDBⁱ	O60911
TreeFamⁱ	TF313739

Enzyme and pathway databases

BRENDAⁱ	3.4.22.43 2681
Reactomeⁱ	R-HSA-1236977 Endosomal/Vacuolar pathway R-HSA-1474228 Degradation of the extracellular matrix R-HSA-1592389 Activation of Matrix Metalloproteinases R-HSA-1679131 Trafficking and processing of endosomal TLR R-HSA-2022090 Assembly of collagen fibrils and other multimeric structures R-HSA-2132295 MHC class II antigen presentation R-HSA-8939242 RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
SABIO-RKⁱ	O60911

Miscellaneous databases

ChiTaRSⁱ	CTSV human
EvolutionaryTraceⁱ	O60911
GeneWikiⁱ	Cathepsin_L2
GenomeRNAiⁱ	1515
Protein Ontology More...PROⁱ	PR:O60911
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000136943 Expressed in 175 organ(s), highest expression level in hair follicle
CleanExⁱ	HS_CTSL2
ExpressionAtlasⁱ	O60911 baseline and differential
Genevisibleⁱ	O60911 HS

Family and domain databases

CDDⁱ	cd02248 Peptidase_C1A, 1 hit
InterProⁱ	View protein in InterPro IPR038765 Papain_like_cys_pep_sf IPR025661 Pept_asp_AS IPR000169 Pept_cys_AS IPR025660 Pept_his_AS IPR013128 Peptidase_C1A IPR000668 Peptidase_C1A_C IPR039417 Peptidase_C1A_papain-like IPR013201 Prot_inhib_I29
PANTHERⁱ	PTHR12411 PTHR12411, 1 hit
Pfamⁱ	View protein in Pfam PF08246 Inhibitor_I29, 1 hit PF00112 Peptidase_C1, 1 hit
PRINTSⁱ	PR00705 PAPAIN
SMARTⁱ	View protein in SMART SM00848 Inhibitor_I29, 1 hit SM00645 Pept_C1, 1 hit
SUPFAMⁱ	SSF54001 SSF54001, 1 hit
PROSITEⁱ	View protein in PROSITE PS00640 THIOL_PROTEASE_ASN, 1 hit PS00139 THIOL_PROTEASE_CYS, 1 hit PS00639 THIOL_PROTEASE_HIS, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	CATL2_HUMAN
Accessionⁱ	O60911Primary (citable) accession number: O60911 Secondary accession number(s): O60233, Q2TB86, Q5T1U0
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 15, 1998
	Last sequence update:	December 1, 2000
	Last modified:	November 7, 2018
	This is version 182 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
Peptidase families
Classification of peptidase families and list of entries
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 9
Human chromosome 9: entries, gene names and cross-references to MIM

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UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O60911 (CATL2_HUMAN)

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Cathepsin L2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

Protein family/group databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Lysosome

Extracellular region or secreted

Lysosome

Plasma Membrane

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Chemistry databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

Chemistry databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Chemistry databases

Protein family/group databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ