KIN

Functionⁱ

Involved in DNA replication and the cellular response to DNA damage. May participate in DNA replication factories and create a bridge between DNA replication and repair mediated by high molecular weight complexes. May play a role in illegitimate recombination and regulation of gene expression. May participate in mRNA processing. Binds, in vitro, to double-stranded DNA. Also shown to bind preferentially to curved DNA in vitro and in vivo (By similarity). Binds via its C-terminal domain to RNA in vitro.By similarity6 Publications

Miscellaneous

Recognized by antibodies directed against the RecA protein.By similarity

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	28 – 50	C2H2-typeSequence analysisAdd BLAST		23

GO - Molecular functionⁱ

DNA binding
Source: ProtInc
Traceable author statementⁱ
- 1923796
double-stranded DNA binding Source: UniProtKB
metal ion binding Source: UniProtKB-KW
RNA binding
Source: UniProtKB
Inferred from direct assayⁱ
- 17045609

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cellular response to DNA damage stimulus
Source: UniProtKB
Inferred from expression patternⁱ
- 12853634
DNA recombination Source: UniProtKB-KW
DNA repair Source: UniProtKB-KW
DNA replication
Source: UniProtKB
Inferred from direct assayⁱ
- 12359749
mRNA processing
Source: UniProtKB
Traceable author statementⁱ
- 17045609
viral process Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	DNA-binding, RNA-binding
Biological process	DNA damage, DNA recombination, DNA repair, DNA replication, Host-virus interaction, mRNA processing, Stress response
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-HSA-8876725 Protein methylation

Reactomeⁱ

R-HSA-8876725 Protein methylation

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: DNA/RNA-binding protein KIN17 Alternative name(s): Binding to curved DNA KIN, antigenic determinant of recA protein homolog
Gene namesⁱ	Name:KINImported Synonyms:BTCD, KIN17
Organismⁱ	Homo sapiens (Human)
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo
Proteomesⁱ	UP000005640 Componentⁱ: Chromosome 10

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000151657.11
Human Gene Nomenclature Database More...HGNCⁱ	HGNC:6327 KIN
MIMⁱ	601720 gene
neXtProtⁱ	NX_O60870

Keywords - Cellular componentⁱ

Cytoplasm, Nucleus

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Length
Mutagenesisⁱ	135	K → R: Almost complete loss of in vitro methylation by METTL22. 1 Publication	1
Mutagenesisⁱ	302	K → E: Significant reduction of RNA-binding activity. 1 Publication	1
Mutagenesisⁱ	391	K → E: Significant reduction of RNA-binding activity. 1 Publication	1

Organism-specific databases

DisGeNET More...DisGeNETⁱ	22944
Open Targets More...OpenTargetsⁱ	ENSG00000151657
PharmGKBⁱ	PA30113

Polymorphism and mutation databases

BioMutaⁱ	KIN

BioMutaⁱ

KIN

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000289134	1 – 393	DNA/RNA-binding protein KIN17Add BLAST		393

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Modified residueⁱ	135	N6,N6,N6-trimethyllysine; by METTL22; in vitroCombined sources1 Publication		1
Modified residueⁱ	135	N6-methyllysineCombined sources		1

Keywords - PTMⁱ

Methylation

Proteomic databases

EPDⁱ	O60870
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O60870
PaxDbⁱ	O60870
PeptideAtlas More...PeptideAtlasⁱ	O60870
PRIDEⁱ	O60870
ProteomicsDBⁱ	49638

PTM databases

iPTMnetⁱ	O60870
PhosphoSitePlusⁱ	O60870

Expressionⁱ

Tissue specificityⁱ

Ubiquitously expressed in all tissues examined, with highest levels in skeletal muscle, heart and testis. Differentially expressed in non-tumorigenic and tumorigenic cell lines. Highly expressed in proliferating epithelial keratinocyte cells in vitro (at protein level).2 Publications

Inductionⁱ

By UVC irradiation in quiescent primary fibroblasts. By mitomycin C in human melanoma MeWO cells.2 Publications

Gene expression databases

Bgeeⁱ	ENSG00000151657 Expressed in 217 organ(s), highest expression level in lung
CleanExⁱ	HS_KIN
ExpressionAtlasⁱ	O60870 baseline and differential
Genevisibleⁱ	O60870 HS

Organism-specific databases

Human Protein Atlas More...HPAⁱ	CAB016339 HPA038700

HPAⁱ

CAB016339
HPA038700

Interactionⁱ

Subunit structureⁱ

Associated with DNA polymerase alpha, RFC1 and cyclin A, in multiprotein DNA replication complexes. Also associates with replication origins at the G1/S phase boundary and throughout the S phase in vivo.1 Publication

(Microbial infection) Interacts with SV40 large T antigen.1 Publication

Protein-protein interaction databases

BioGridⁱ	116600, 13 interactors
CORUMⁱ	O60870
IntActⁱ	O60870, 3 interactors
Molecular INTeraction database More...MINTⁱ	O60870
STRINGⁱ	9606.ENSP00000368881

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Helixⁱ	61 – 63	Combined sources	3
Helixⁱ	65 – 83	Combined sources	19
Beta strandⁱ	88 – 90	Combined sources	3
Helixⁱ	91 – 98	Combined sources	8
Helixⁱ	107 – 109	Combined sources	3
Helixⁱ	115 – 122	Combined sources	8
Turnⁱ	123 – 126	Combined sources	4
Beta strandⁱ	127 – 133	Combined sources	7
Beta strandⁱ	136 – 141	Combined sources	6
Helixⁱ	146 – 154	Combined sources	9
Helixⁱ	156 – 158	Combined sources	3
Beta strandⁱ	285 – 289	Combined sources	5
Helixⁱ	296 – 298	Combined sources	3
Beta strandⁱ	302 – 309	Combined sources	8
Turnⁱ	310 – 312	Combined sources	3
Beta strandⁱ	313 – 318	Combined sources	6
Turnⁱ	319 – 321	Combined sources	3
Beta strandⁱ	324 – 328	Combined sources	5
Helixⁱ	329 – 331	Combined sources	3
Beta strandⁱ	332 – 334	Combined sources	3
Beta strandⁱ	342 – 345	Combined sources	4
Turnⁱ	349 – 352	Combined sources	4
Beta strandⁱ	354 – 361	Combined sources	8
Helixⁱ	362 – 364	Combined sources	3
Beta strandⁱ	366 – 371	Combined sources	6
Turnⁱ	375 – 378	Combined sources	4
Beta strandⁱ	380 – 385	Combined sources	6
Helixⁱ	386 – 388	Combined sources	3
Beta strandⁱ	389 – 392	Combined sources	4

Show more details

3D structure databases

ProteinModelPortalⁱ	O60870
SMRⁱ	O60870
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Miscellaneous databases

EvolutionaryTraceⁱ	O60870

EvolutionaryTraceⁱ

O60870

Family & Domainsⁱ

Region

Feature key	Position(s)	DescriptionActions	Length
Regionⁱ	51 – 160	Winged helix-turn-helix (wHTH)Add BLAST	110
Regionⁱ	284 – 334	C-terminal subdomain A1 PublicationAdd BLAST	51
Regionⁱ	340 – 391	C-terminal subdomain B1 PublicationAdd BLAST	52

Coiled coil

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Coiled coilⁱ	147 – 180	Sequence analysisAdd BLAST		34
Coiled coilⁱ	250 – 277	Sequence analysisAdd BLAST		28

Domainⁱ

The C-terminal domain (268-393) is organized into 2 subdomains that bear structural similarities to SH3-like domains. Both subdomains adopt a similar 5-stranded beta-barrel-like fold and are connected to each other by a short linker of 5 residues. The 5 beta-sheets are packed at approximately right angles against each other. A highly conserved groove formed at the interface between the 2 subdomains, comprised of Lys residues 302 and 391 and other positively charged residues, may possibly be the site of RNA-binding.1 Publication

Sequence similaritiesⁱ

Belongs to the KIN17 family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	28 – 50	C2H2-typeSequence analysisAdd BLAST		23

Keywords - Domainⁱ

Coiled coil, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG2837 Eukaryota ENOG410XRJ7 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00390000005903
HOGENOMⁱ	HOG000178663
HOVERGENⁱ	HBG053068
InParanoidⁱ	O60870
KEGG Orthology (KO) More...KOⁱ	K13102
OMAⁱ	WLQPNIV
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0AQX
PhylomeDBⁱ	O60870
TreeFamⁱ	TF314393

Family and domain databases

Gene3Dⁱ	1.10.10.2030, 1 hit 2.30.30.30, 1 hit
InterProⁱ	View protein in InterPro IPR019447 DNA/RNA-bd_Kin17_cons_domain IPR037321 KIN17-like IPR038254 KIN17_WH-like_sf IPR014722 Rib_L2_dom2 IPR036236 Znf_C2H2_sf
PANTHERⁱ	PTHR12805 PTHR12805, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF10357 Kin17_mid, 1 hit
SMARTⁱ	View protein in SMART SM01253 Kin17_mid, 1 hit
SUPFAMⁱ	SSF57667 SSF57667, 1 hit
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 1 hit

Sequences (2+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 2 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 2 described isoforms and 1 potential isoform that is computationally mapped.Show all Align All

Isoform 1 (identifier: O60870-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MGKSDFLTPK AIANRIKSKG LQKLRWYCQM CQKQCRDENG FKCHCMSESH 
        60         70         80         90        100
QRQLLLASEN PQQFMDYFSE EFRNDFLELL RRRFGTKRVH NNIVYNEYIS 
       110        120        130        140        150
HREHIHMNAT QWETLTDFTK WLGREGLCKV DETPKGWYIQ YIDRDPETIR 
       160        170        180        190        200
RQLELEKKKK QDLDDEEKTA KFIEEQVRRG LEGKEQEVPT FTELSRENDE 
       210        220        230        240        250
EKVTFNLSKG ACSSSGATSS KSSTLGPSAL KTIGSSASVK RKESSQSSTQ 
       260        270        280        290        300
SKEKKKKKSA LDEIMEIEEE KKRTARTDYW LQPEIIVKII TKKLGEKYHK 
       310        320        330        340        350
KKAIVKEVID KYTAVVKMID SGDKLKLDQT HLETVIPAPG KRILVLNGGY 
       360        370        380        390 
RGNEGTLESI NEKTFSATIV IETGPLKGRR VEGIQYEDIS KLA

Length:393

Mass (Da):45,374

Last modified:January 1, 1999 - v2

Checksum:ⁱ515A89B4C8A4C007

GO

Isoform 2 (identifier: O60870-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
374-393: GPLKGRRVEGIQYEDISKLA → V

« Hide

        10         20         30         40         50
MGKSDFLTPK AIANRIKSKG LQKLRWYCQM CQKQCRDENG FKCHCMSESH 
        60         70         80         90        100
QRQLLLASEN PQQFMDYFSE EFRNDFLELL RRRFGTKRVH NNIVYNEYIS 
       110        120        130        140        150
HREHIHMNAT QWETLTDFTK WLGREGLCKV DETPKGWYIQ YIDRDPETIR 
       160        170        180        190        200
RQLELEKKKK QDLDDEEKTA KFIEEQVRRG LEGKEQEVPT FTELSRENDE 
       210        220        230        240        250
EKVTFNLSKG ACSSSGATSS KSSTLGPSAL KTIGSSASVK RKESSQSSTQ 
       260        270        280        290        300
SKEKKKKKSA LDEIMEIEEE KKRTARTDYW LQPEIIVKII TKKLGEKYHK 
       310        320        330        340        350
KKAIVKEVID KYTAVVKMID SGDKLKLDQT HLETVIPAPG KRILVLNGGY 
       360        370 
RGNEGTLESI NEKTFSATIV IETV

Note: No experimental confirmation available.

Show »

Length:374

Mass (Da):43,261

Checksum:ⁱ4507B25B386B68F7

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	S4R357	S4R357_HUMAN		DNA/RNA-binding protein KIN17 DNA/RNA-binding protein KIN17	KIN	108	Annotation score:

Alternative sequence

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Alternative sequenceⁱVSP_056074	374 – 393	GPLKG…ISKLA → V in isoform 2. 1 PublicationAdd BLAST		20

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ005273 mRNA Translation: CAA06462.1 AK301789 mRNA Translation: BAG63244.1 AL158044 Genomic DNA No translation available. BC017309 mRNA Translation: AAH17309.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS7080.1 [O60870-1]
NCBI Reference Sequences More...RefSeqⁱ	NP_036443.1, NM_012311.3 [O60870-1] XP_011517729.1, XM_011519427.1 [O60870-2]
UniGeneⁱ	Hs.397918

Genome annotation databases

Ensemblⁱ	ENST00000379562; ENSP00000368881; ENSG00000151657 [O60870-1]
GeneIDⁱ	22944
KEGGⁱ	hsa:22944
UCSC genome browser More...UCSCⁱ	uc001ijt.4 human [O60870-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

100% Identity
90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O60870	KIN isoform 1		PANTR		393	UniRef100_O60870
Uncharacterized protein		PANPA		393
UPI0007DC703E		HUMAN		287
O60870-2	DNA/RNA-binding protein KIN17 (Fragment)		HUMAN		108	UniRef100_O60870-2
KIN isoform 5 (Fragment)		PANTR		108
UPI0003EAEF37		HUMAN		394
UPI000206596D		HUMAN		288

Protein	Similar proteins		Species	Score	Length	Source
O60870	KIN isoform 1		PANTR		393	UniRef90_O60870
Uncharacterized protein		PANPA		393
Uncharacterized protein		NOMLE		395
Uncharacterized protein		CERAT		394
DNA/RNA-binding protein KIN17		MACMU		393
+123

Protein	Similar proteins		Species	Score	Length	Source
O60870	DNA/RNA-binding protein KIN17		MOUSE		391	UniRef50_O60870
KIN isoform 1		PANTR		393
Uncharacterized protein		PANPA		393
Uncharacterized protein		NOMLE		395
Uncharacterized protein		CERAT		394
+457

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AJ005273 mRNA Translation: CAA06462.1 AK301789 mRNA Translation: BAG63244.1 AL158044 Genomic DNA No translation available. BC017309 mRNA Translation: AAH17309.1
CCDSⁱ	CCDS7080.1 [O60870-1]
RefSeqⁱ	NP_036443.1, NM_012311.3 [O60870-1] XP_011517729.1, XM_011519427.1 [O60870-2]
UniGeneⁱ	Hs.397918

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	2CKK	X-ray	1.45	A	268-393	[»]
	2V1N	NMR	-	A	51-160	[»]
ProteinModelPortalⁱ	O60870
SMRⁱ	O60870
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	116600, 13 interactors
CORUMⁱ	O60870
IntActⁱ	O60870, 3 interactors
MINTⁱ	O60870
STRINGⁱ	9606.ENSP00000368881

PTM databases

iPTMnetⁱ	O60870
PhosphoSitePlusⁱ	O60870

Polymorphism and mutation databases

BioMutaⁱ	KIN

BioMutaⁱ

KIN

Proteomic databases

EPDⁱ	O60870
MaxQBⁱ	O60870
PaxDbⁱ	O60870
PeptideAtlasⁱ	O60870
PRIDEⁱ	O60870
ProteomicsDBⁱ	49638

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENST00000379562; ENSP00000368881; ENSG00000151657 [O60870-1]
GeneIDⁱ	22944
KEGGⁱ	hsa:22944
UCSCⁱ	uc001ijt.4 human [O60870-1]

Organism-specific databases

CTDⁱ	22944
DisGeNETⁱ	22944
EuPathDBⁱ	HostDB:ENSG00000151657.11
GeneCardsⁱ	KIN
HGNCⁱ	HGNC:6327 KIN
HPAⁱ	CAB016339 HPA038700
MIMⁱ	601720 gene
neXtProtⁱ	NX_O60870
OpenTargetsⁱ	ENSG00000151657
PharmGKBⁱ	PA30113
GenAtlas: human gene database More...GenAtlasⁱ	Search...

Phylogenomic databases

eggNOGⁱ	KOG2837 Eukaryota ENOG410XRJ7 LUCA
GeneTreeⁱ	ENSGT00390000005903
HOGENOMⁱ	HOG000178663
HOVERGENⁱ	HBG053068
InParanoidⁱ	O60870
KOⁱ	K13102
OMAⁱ	WLQPNIV
OrthoDBⁱ	EOG091G0AQX
PhylomeDBⁱ	O60870
TreeFamⁱ	TF314393

Enzyme and pathway databases

Reactomeⁱ	R-HSA-8876725 Protein methylation

Reactomeⁱ

R-HSA-8876725 Protein methylation

Miscellaneous databases

ChiTaRSⁱ	KIN human
EvolutionaryTraceⁱ	O60870
GeneWikiⁱ	KIN_(gene)
GenomeRNAiⁱ	22944
Protein Ontology More...PROⁱ	PR:O60870
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSG00000151657 Expressed in 217 organ(s), highest expression level in lung
CleanExⁱ	HS_KIN
ExpressionAtlasⁱ	O60870 baseline and differential
Genevisibleⁱ	O60870 HS

Family and domain databases

Gene3Dⁱ	1.10.10.2030, 1 hit 2.30.30.30, 1 hit
InterProⁱ	View protein in InterPro IPR019447 DNA/RNA-bd_Kin17_cons_domain IPR037321 KIN17-like IPR038254 KIN17_WH-like_sf IPR014722 Rib_L2_dom2 IPR036236 Znf_C2H2_sf
PANTHERⁱ	PTHR12805 PTHR12805, 1 hit
Pfamⁱ	View protein in Pfam PF10357 Kin17_mid, 1 hit
SMARTⁱ	View protein in SMART SM01253 Kin17_mid, 1 hit
SUPFAMⁱ	SSF57667 SSF57667, 1 hit
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	KIN17_HUMAN
Accessionⁱ	O60870Primary (citable) accession number: O60870 Secondary accession number(s): B4DX32
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	May 29, 2007
	Last sequence update:	January 1, 1999
	Last modified:	November 7, 2018
	This is version 163 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references
Human chromosome 10
Human chromosome 10: entries, gene names and cross-references to MIM

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UniProtKB - O60870 (KIN17_HUMAN)

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DNA/RNA-binding protein KIN17

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<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Organism-specific databases

Polymorphism and mutation databases

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Organism-specific databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

Miscellaneous databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Coiled coil

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Polymorphism and mutation databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ