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UniProtKB - O60732 (MAGC1_HUMAN)

Entry version 145 (02 Dec 2020)
Sequence version 3 (27 Jun 2006)
Previous versions | rss
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Protein

Melanoma-associated antigen C1

Gene

MAGEC1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionTumor antigen

Enzyme and pathway databases

Pathway Commons web resource for biological pathway data

More...PathwayCommonsi		O60732

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Melanoma-associated antigen C1
Alternative name(s):
Cancer/testis antigen 7.1
Short name:
CT7.1
MAGE-C1 antigen
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:MAGEC1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome X

Organism-specific databases

Eukaryotic Pathogen and Host Database Resources

More...EuPathDBi		HostDB:ENSG00000155495.8

Human Gene Nomenclature Database

More...HGNCi		HGNC:6812, MAGEC1

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		300223, gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_O60732

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...DisGeNETi		9947

Open Targets

More...OpenTargetsi		ENSG00000155495

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA30558

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		O60732, Tbio

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		MAGEC1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001567201 – 1142Melanoma-associated antigen C1Add BLAST1142

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei63PhosphoserineCombined sources1
Modified residuei207PhosphoserineCombined sources1
Modified residuei382PhosphoserineCombined sources1
Modified residuei1063PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		O60732

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		O60732

MaxQB - The MaxQuant DataBase

More...MaxQBi		O60732

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		O60732

PeptideAtlas

More...PeptideAtlasi		O60732

PRoteomics IDEntifications database

More...PRIDEi		O60732

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		49577 [O60732-1]
77

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		O60732

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		O60732

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in testis and in tumors of a wide variety of histologic types.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000155495, Expressed in right testis and 27 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		O60732, HS

Organism-specific databases

Human Protein Atlas

More...HPAi		ENSG00000155495, Tissue enriched (testis)

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection">Interaction</a>' section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="https://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated at every <a href="http://www.uniprot.org/help/synchronization">UniProt release</a>.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		115272, 11 interactors

Protein interaction database and analysis system

More...IntActi		O60732, 8 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000285879

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		O60732, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		O60732

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini908 – 1106MAGEPROSITE-ProRule annotationAdd BLAST199

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG4562, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00940000164535

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_277023_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		O60732

Identification of Orthologs from Complete Genome Data

More...OMAi		HYFPQSP

Database of Orthologous Groups

More...OrthoDBi		1195799at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		O60732

TreeFam database of animal gene trees

More...TreeFami		TF328505

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.10.1200, 1 hit
1.10.10.1210, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR037445, MAGE
IPR041898, MAGE_WH1
IPR041899, MAGE_WH2
IPR002190, MHD_dom

The PANTHER Classification System

More...PANTHERi		PTHR11736, PTHR11736, 11 hits

Pfam protein domain database

More...Pfami		View protein in Pfam
PF01454, MAGE, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM01373, MAGE, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS50838, MAGE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: O60732-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MGDKDMPTAG MPSLLQSSSE SPQSCPEGED SQSPLQIPQS SPESDDTLYP 
        60         70         80         90        100
LQSPQSRSEG EDSSDPLQRP PEGKDSQSPL QIPQSSPEGD DTQSPLQNSQ 
       110        120        130        140        150
SSPEGKDSLS PLEISQSPPE GEDVQSPLQN PASSFFSSAL LSIFQSSPES 
       160        170        180        190        200
TQSPFEGFPQ SVLQIPVSAA SSSTLVSIFQ SSPESTQSPF EGFPQSPLQI 
       210        220        230        240        250
PVSRSFSSTL LSIFQSSPER TQSTFEGFAQ SPLQIPVSPS SSSTLLSLFQ 
       260        270        280        290        300
SFSERTQSTF EGFAQSSLQI PVSPSFSSTL VSLFQSSPER TQSTFEGFPQ 
       310        320        330        340        350
SPLQIPVSSS SSSTLLSLFQ SSPERTHSTF EGFPQSLLQI PMTSSFSSTL 
       360        370        380        390        400
LSIFQSSPES AQSTFEGFPQ SPLQIPGSPS FSSTLLSLFQ SSPERTHSTF 
       410        420        430        440        450
EGFPQSPLQI PMTSSFSSTL LSILQSSPES AQSAFEGFPQ SPLQIPVSSS 
       460        470        480        490        500
FSYTLLSLFQ SSPERTHSTF EGFPQSPLQI PVSSSSSSST LLSLFQSSPE 
       510        520        530        540        550
CTQSTFEGFP QSPLQIPQSP PEGENTHSPL QIVPSLPEWE DSLSPHYFPQ 
       560        570        580        590        600
SPPQGEDSLS PHYFPQSPPQ GEDSLSPHYF PQSPQGEDSL SPHYFPQSPP 
       610        620        630        640        650
QGEDSMSPLY FPQSPLQGEE FQSSLQSPVS ICSSSTPSSL PQSFPESSQS 
       660        670        680        690        700
PPEGPVQSPL HSPQSPPEGM HSQSPLQSPE SAPEGEDSLS PLQIPQSPLE 
       710        720        730        740        750
GEDSLSSLHF PQSPPEWEDS LSPLHFPQFP PQGEDFQSSL QSPVSICSSS 
       760        770        780        790        800
TSLSLPQSFP ESPQSPPEGP AQSPLQRPVS SFFSYTLASL LQSSHESPQS 
       810        820        830        840        850
PPEGPAQSPL QSPVSSFPSS TSSSLSQSSP VSSFPSSTSS SLSKSSPESP 
       860        870        880        890        900
LQSPVISFSS STSLSPFSEE SSSPVDEYTS SSDTLLESDS LTDSESLIES 
       910        920        930        940        950
EPLFTYTLDE KVDELARFLL LKYQVKQPIT KAEMLTNVIS RYTGYFPVIF 
       960        970        980        990       1000
RKAREFIEIL FGISLREVDP DDSYVFVNTL DLTSEGCLSD EQGMSQNRLL 
      1010       1020       1030       1040       1050
ILILSIIFIK GTYASEEVIW DVLSGIGVRA GREHFAFGEP RELLTKVWVQ 
      1060       1070       1080       1090       1100
EHYLEYREVP NSSPPRYEFL WGPRAHSEVI KRKVVEFLAM LKNTVPITFP 
      1110       1120       1130       1140 
SSYKDALKDV EERAQAIIDT TDDSTATESA SSSVMSPSFS SE
Length:1,142
Mass (Da):123,643
Last modified:June 27, 2006 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6C9AE820156F3C50
GO
Isoform 2 (identifier: O60732-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-933: Missing.

Show »
Length:209
Mass (Da):23,747
Checksum:i402F6EAF6A78C72B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti221 – 225TQSTF → SQRTS (PubMed:9485030).Curated5
Sequence conflicti221 – 225TQSTF → SQRTS (PubMed:9618514).Curated5
Sequence conflicti239P → S (PubMed:9485030).Curated1
Sequence conflicti239P → S (PubMed:9618514).Curated1
Sequence conflicti252 – 253FS → SP (PubMed:9485030).Curated2
Sequence conflicti252 – 253FS → SP (PubMed:9618514).Curated2
Sequence conflicti264A → P (PubMed:9485030).Curated1
Sequence conflicti264A → P (PubMed:9618514).Curated1
Sequence conflicti267S → P (PubMed:9485030).Curated1
Sequence conflicti267S → P (PubMed:9618514).Curated1
Sequence conflicti274P → R (PubMed:9485030).Curated1
Sequence conflicti274P → R (PubMed:9618514).Curated1
Sequence conflicti281 – 283VSL → LSI (PubMed:9485030).Curated3
Sequence conflicti281 – 283VSL → LSI (PubMed:9618514).Curated3
Sequence conflicti299P → A (PubMed:9485030).Curated1
Sequence conflicti299P → A (PubMed:9618514).Curated1
Sequence conflicti309 – 311SSS → PSF in AAC24227 (PubMed:9618514).Curated3
Sequence conflicti316 – 318LSL → VSI in AAC24227 (PubMed:9618514).Curated3
Sequence conflicti337L → P in AAC24227 (PubMed:9618514).Curated1
Sequence conflicti342 – 343MT → VS in AAC24227 (PubMed:9618514).Curated2
Sequence conflicti353I → L in AAC24227 (PubMed:9618514).Curated1
Sequence conflicti360 – 361SA → RT in AAC24227 (PubMed:9618514).Curated2
Sequence conflicti467H → Q in AAC18837 (PubMed:9485030).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_05350125C → Y1 PublicationCorresponds to variant dbSNP:rs176036Ensembl.1
Natural variantiVAR_053502151T → I2 PublicationsCorresponds to variant dbSNP:rs176037Ensembl.1
Natural variantiVAR_053503257Q → H. Corresponds to variant dbSNP:rs143440588Ensembl.1
Natural variantiVAR_053504276F → S. Corresponds to variant dbSNP:rs75148863Ensembl.1
Natural variantiVAR_060068327H → Q2 PublicationsCorresponds to variant dbSNP:rs176047Ensembl.1
Natural variantiVAR_062121709H → Y. Corresponds to variant dbSNP:rs56256227Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0563821 – 933Missing in isoform 2. 1 PublicationAdd BLAST933

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF064589 Genomic DNA Translation: AAC18837.1
AF056334 mRNA Translation: AAC24227.1
AL022152 Genomic DNA No translation available.
BC127771 mRNA Translation: AAI27772.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS35417.1 [O60732-1]

NCBI Reference Sequences

More...RefSeqi		NP_005453.2, NM_005462.4 [O60732-1]
XP_011529720.1, XM_011531418.2 [O60732-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000285879; ENSP00000285879; ENSG00000155495 [O60732-1]
ENST00000406005; ENSP00000385500; ENSG00000155495 [O60732-2]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		9947

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:9947

UCSC genome browser

More...UCSCi		uc004fbt.4, human [O60732-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF064589 Genomic DNA Translation: AAC18837.1
AF056334 mRNA Translation: AAC24227.1
AL022152 Genomic DNA No translation available.
BC127771 mRNA Translation: AAI27772.1
CCDSiCCDS35417.1 [O60732-1]
RefSeqiNP_005453.2, NM_005462.4 [O60732-1]
XP_011529720.1, XM_011531418.2 [O60732-1]

3D structure databases

SMRiO60732
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi115272, 11 interactors
IntActiO60732, 8 interactors
STRINGi9606.ENSP00000285879

PTM databases

iPTMnetiO60732
PhosphoSitePlusiO60732

Polymorphism and mutation databases

BioMutaiMAGEC1

Proteomic databases

EPDiO60732
MassIVEiO60732
MaxQBiO60732
PaxDbiO60732
PeptideAtlasiO60732
PRIDEiO60732
ProteomicsDBi49577 [O60732-1]
77

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		528, 139 antibodies

Genome annotation databases

EnsembliENST00000285879; ENSP00000285879; ENSG00000155495 [O60732-1]
ENST00000406005; ENSP00000385500; ENSG00000155495 [O60732-2]
GeneIDi9947
KEGGihsa:9947
UCSCiuc004fbt.4, human [O60732-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		9947
DisGeNETi9947
EuPathDBiHostDB:ENSG00000155495.8

GeneCards: human genes, protein and diseases

More...GeneCardsi		MAGEC1
HGNCiHGNC:6812, MAGEC1
HPAiENSG00000155495, Tissue enriched (testis)
MIMi300223, gene
neXtProtiNX_O60732
OpenTargetsiENSG00000155495
PharmGKBiPA30558

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiKOG4562, Eukaryota
GeneTreeiENSGT00940000164535
HOGENOMiCLU_277023_0_0_1
InParanoidiO60732
OMAiHYFPQSP
OrthoDBi1195799at2759
PhylomeDBiO60732
TreeFamiTF328505

Enzyme and pathway databases

PathwayCommonsiO60732

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		9947, 5 hits in 470 CRISPR screens

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		9947
PharosiO60732, Tbio

Protein Ontology

More...PROi		PR:O60732
RNActiO60732, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000155495, Expressed in right testis and 27 other tissues
GenevisibleiO60732, HS

Family and domain databases

Gene3Di1.10.10.1200, 1 hit
1.10.10.1210, 1 hit
InterProiView protein in InterPro
IPR037445, MAGE
IPR041898, MAGE_WH1
IPR041899, MAGE_WH2
IPR002190, MHD_dom
PANTHERiPTHR11736, PTHR11736, 11 hits
PfamiView protein in Pfam
PF01454, MAGE, 1 hit
SMARTiView protein in SMART
SM01373, MAGE, 1 hit
PROSITEiView protein in PROSITE
PS50838, MAGE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiMAGC1_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O60732
Secondary accession number(s): A0PK03, O75451, Q8TCV4
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: June 27, 2006
Last modified: December 2, 2020
This is version 145 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. Human chromosome X
    Human chromosome X: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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