UniProtKB - O60337 (MARH6_HUMAN)
E3 ubiquitin-protein ligase MARCHF6
MARCHF6
Functioni
E3 ubiquitin-protein ligase that promotes 'Lys-48'-linked ubiquitination of target proteins, leading to their proteasomal degradation (PubMed:15673284).
Promotes ubiquitination of DIO2, leading to its degradation (PubMed:19651899).
Promotes ubiquitination of SQLE, leading to its degradation (PubMed:24449766).
E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May cooperate with UBE2G1 (PubMed:15673284).
3 PublicationsCatalytic activityi
- S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.1 Publication EC:2.3.2.27
: protein ubiquitination Pathwayi
This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.1 PublicationView all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 9 | Zinc 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 12 | Zinc 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 26 | Zinc 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 28 | Zinc 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 36 | Zinc 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 39 | Zinc 1PROSITE-ProRule annotation | 1 | |
Metal bindingi | 52 | Zinc 2PROSITE-ProRule annotation | 1 | |
Metal bindingi | 55 | Zinc 2PROSITE-ProRule annotation | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 1 – 62 | RING-CH-typePROSITE-ProRule annotationAdd BLAST | 62 |
GO - Molecular functioni
- enzyme binding Source: UniProtKB
- ubiquitin conjugating enzyme binding Source: UniProtKB
- ubiquitin protein ligase activity Source: UniProtKB
- ubiquitin-protein transferase activity Source: UniProtKB
- ubiquitin-specific protease binding Source: ParkinsonsUK-UCL
- zinc ion binding Source: InterPro
GO - Biological processi
- endoplasmic reticulum mannose trimming Source: Reactome
- ERAD pathway Source: ParkinsonsUK-UCL
- proteasomal protein catabolic process Source: ParkinsonsUK-UCL
- proteasome-mediated ubiquitin-dependent protein catabolic process Source: UniProtKB
- protein K48-linked ubiquitination Source: UniProtKB
- protein ubiquitination Source: UniProtKB
- ubiquitin-dependent ERAD pathway Source: GO_Central
Keywordsi
Molecular function | Transferase |
Biological process | Ubl conjugation pathway |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
BRENDAi | 2.3.2.27, 2681 |
PathwayCommonsi | O60337 |
Reactomei | R-HSA-901032, ER Quality Control Compartment (ERQC) |
SignaLinki | O60337 |
UniPathwayi | UPA00143 |
Names & Taxonomyi
Protein namesi | Recommended name: E3 ubiquitin-protein ligase MARCHF6 (EC:2.3.2.272 Publications)Alternative name(s): Doa10 homolog Membrane-associated RING finger protein 6 Membrane-associated RING-CH protein VI Short name: MARCH-VI1 Publication Protein TEB-43 Publications RING finger protein 176 RING-type E3 ubiquitin transferase MARCHF6Curated |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:30550, MARCHF6 |
MIMi | 613297, gene |
neXtProti | NX_O60337 |
VEuPathDBi | HostDB:ENSG00000145495 |
Subcellular locationi
Endoplasmic reticulum
- Endoplasmic reticulum membrane 1 Publication; Multi-pass membrane protein 1 Publication
Endoplasmic reticulum
- endoplasmic reticulum Source: HPA
- endoplasmic reticulum membrane Source: Reactome
- endoplasmic reticulum quality control compartment Source: GOC
- ER ubiquitin ligase complex Source: ParkinsonsUK-UCL
- integral component of endoplasmic reticulum membrane Source: UniProtKB
Other locations
- integral component of membrane Source: ParkinsonsUK-UCL
- membrane Source: UniProtKB
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 91 | Cytoplasmic2 PublicationsAdd BLAST | 91 | |
Transmembranei | 92 – 112 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 113 – 142 | ExtracellularSequence analysisAdd BLAST | 30 | |
Transmembranei | 143 – 163 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 164 – 283 | CytoplasmicSequence analysisAdd BLAST | 120 | |
Transmembranei | 284 – 304 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 305 – 336 | ExtracellularSequence analysisAdd BLAST | 32 | |
Transmembranei | 337 – 357 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 358 – 376 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 377 – 397 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 398 – 421 | ExtracellularSequence analysisAdd BLAST | 24 | |
Transmembranei | 422 – 442 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 443 – 480 | CytoplasmicSequence analysisAdd BLAST | 38 | |
Transmembranei | 481 – 501 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 502 – 519 | ExtracellularSequence analysisAdd BLAST | 18 | |
Transmembranei | 520 – 540 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 541 – 632 | CytoplasmicSequence analysisAdd BLAST | 92 | |
Transmembranei | 633 – 653 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 654 – 678 | ExtracellularSequence analysisAdd BLAST | 25 | |
Transmembranei | 679 – 699 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 700 – 721 | CytoplasmicSequence analysisAdd BLAST | 22 | |
Transmembranei | 722 – 742 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 743 – 764 | ExtracellularSequence analysisAdd BLAST | 22 | |
Transmembranei | 765 – 785 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 786 – 815 | CytoplasmicSequence analysisAdd BLAST | 30 | |
Transmembranei | 816 – 836 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 837 – 848 | ExtracellularSequence analysisAdd BLAST | 12 | |
Transmembranei | 849 – 869 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 870 – 910 | Cytoplasmic1 PublicationAdd BLAST | 41 |
Keywords - Cellular componenti
Endoplasmic reticulum, MembranePathology & Biotechi
Involvement in diseasei
Epilepsy, familial adult myoclonic, 3 (FAME3)1 Publication
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 9 | C → A: Abolishes auto-ubiquitination. Loss of ubiquitin ligase activity. 2 Publications | 1 |
Keywords - Diseasei
EpilepsyOrganism-specific databases
DisGeNETi | 10299 |
MalaCardsi | MARCHF6 |
MIMi | 613608, phenotype |
OpenTargetsi | ENSG00000145495 |
Orphaneti | 86814, Benign adult familial myoclonic epilepsy |
PharmGKBi | PA134869368 |
Miscellaneous databases
Pharosi | O60337, Tbio |
Genetic variation databases
BioMutai | MARCH6 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000274298 | 1 – 910 | E3 ubiquitin-protein ligase MARCHF6Add BLAST | 910 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1 | N-acetylmethionineCombined sources | 1 |
Post-translational modificationi
Keywords - PTMi
Acetylation, Ubl conjugationProteomic databases
EPDi | O60337 |
jPOSTi | O60337 |
MassIVEi | O60337 |
MaxQBi | O60337 |
PaxDbi | O60337 |
PeptideAtlasi | O60337 |
PRIDEi | O60337 |
ProteomicsDBi | 4463 49363 [O60337-4] 5070 |
PTM databases
iPTMneti | O60337 |
PhosphoSitePlusi | O60337 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000145495, Expressed in cerebellar vermis and 253 other tissues |
ExpressionAtlasi | O60337, baseline and differential |
Genevisiblei | O60337, HS |
Organism-specific databases
HPAi | ENSG00000145495, Low tissue specificity |
Interactioni
Subunit structurei
Binary interactionsi
O60337
With | #Exp. | IntAct |
---|---|---|
ADGRE2 [Q9UHX3] | 3 | EBI-2684600,EBI-11277970 |
RGS2 - isoform 1 [P41220-1] | 3 | EBI-2684600,EBI-16037474 |
GO - Molecular functioni
- enzyme binding Source: UniProtKB
- ubiquitin conjugating enzyme binding Source: UniProtKB
- ubiquitin-specific protease binding Source: ParkinsonsUK-UCL
Protein-protein interaction databases
BioGRIDi | 115587, 51 interactors |
DIPi | DIP-56134N |
IntActi | O60337, 18 interactors |
MINTi | O60337 |
STRINGi | 9606.ENSP00000274140 |
Miscellaneous databases
RNActi | O60337, protein |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 185 – 256 | DisorderedSequence analysisAdd BLAST | 72 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 224 – 246 | Acidic residuesSequence analysisAdd BLAST | 23 |
Domaini
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 1 – 62 | RING-CH-typePROSITE-ProRule annotationAdd BLAST | 62 |
Keywords - Domaini
Transmembrane, Transmembrane helix, Zinc-fingerPhylogenomic databases
eggNOGi | KOG1609, Eukaryota |
GeneTreei | ENSGT00940000155171 |
HOGENOMi | CLU_006373_1_0_1 |
InParanoidi | O60337 |
OMAi | WLPIRIL |
OrthoDBi | 170933at2759 |
PhylomeDBi | O60337 |
TreeFami | TF105777 |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR011016, Znf_RING-CH IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF12906, RINGv, 1 hit |
SMARTi | View protein in SMART SM00744, RINGv, 1 hit |
PROSITEi | View protein in PROSITE PS51292, ZF_RING_CH, 1 hit |
s (3+)i Sequence
Sequence statusi: Complete.
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MDTAEEDICR VCRSEGTPEK PLYHPCVCTG SIKFIHQECL VQWLKHSRKE
60 70 80 90 100
YCELCKHRFA FTPIYSPDMP SRLPIQDIFA GLVTSIGTAI RYWFHYTLVA
110 120 130 140 150
FAWLGVVPLT ACRIYKCLFT GSVSSLLTLP LDMLSTENLL ADCLQGCFVV
160 170 180 190 200
TCTLCAFISL VWLREQIVHG GAPIWLEHAA PPFNAAGHHQ NEAPAGGNGA
210 220 230 240 250
ENVAADQPAN PPAENAVVGE NPDAQDDQAE EEEEDNEEED DAGVEDAADA
260 270 280 290 300
NNGAQDDMNW NALEWDRAAE ELTWERMLGL DGSLVFLEHV FWVVSLNTLF
310 320 330 340 350
ILVFAFCPYH IGHFSLVGLG FEEHVQASHF EGLITTIVGY ILLAITLIIC
360 370 380 390 400
HGLATLVKFH RSRRLLGVCY IVVKVSLLVV VEIGVFPLIC GWWLDICSLE
410 420 430 440 450
MFDATLKDRE LSFQSAPGTT MFLHWLVGMV YVFYFASFIL LLREVLRPGV
460 470 480 490 500
LWFLRNLNDP DFNPVQEMIH LPIYRHLRRF ILSVIVFGSI VLLMLWLPIR
510 520 530 540 550
IIKSVLPNFL PYNVMLYSDA PVSELSLELL LLQVVLPALL EQGHTRQWLK
560 570 580 590 600
GLVRAWTVTA GYLLDLHSYL LGDQEENENS ANQQVNNNQH ARNNNAIPVV
610 620 630 640 650
GEGLHAAHQA ILQQGGPVGF QPYRRPLNFP LRIFLLIVFM CITLLIASLI
660 670 680 690 700
CLTLPVFAGR WLMSFWTGTA KIHELYTAAC GLYVCWLTIR AVTVMVAWMP
710 720 730 740 750
QGRRVIFQKV KEWSLMIMKT LIVAVLLAGV VPLLLGLLFE LVIVAPLRVP
760 770 780 790 800
LDQTPLFYPW QDWALGVLHA KIIAAITLMG PQWWLKTVIE QVYANGIRNI
810 820 830 840 850
DLHYIVRKLA APVISVLLLS LCVPYVIASG VVPLLGVTAE MQNLVHRRIY
860 870 880 890 900
PFLLMVVVLM AILSFQVRQF KRLYEHIKND KYLVGQRLVN YERKSGKQGS
910
SPPPPQSSQE
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A0B4J206 | A0A0B4J206_HUMAN | E3 ubiquitin-protein ligase MARCHF6 | MARCHF6 | 608 | Annotation score: | ||
D6RHY7 | D6RHY7_HUMAN | E3 ubiquitin-protein ligase MARCHF6 | MARCHF6 | 77 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 380 | V → VG in AAB66840 (Ref. 6) Curated | 1 | |
Sequence conflicti | 384 | G → GS in AAB66840 (Ref. 6) Curated | 1 | |
Sequence conflicti | 390 | C → WW in AAB66840 (Ref. 6) Curated | 1 | |
Sequence conflicti | 395 | D → G in AAB66840 (Ref. 6) Curated | 1 | |
Sequence conflicti | 399 | L → LG in AAB66840 (Ref. 6) Curated | 1 | |
Sequence conflicti | 546 | R → K in AAB66840 (Ref. 6) Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_030251 | 622 | P → L1 PublicationCorresponds to variant dbSNP:rs1062914Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_047035 | 7 – 112 | DICRV…PLTAC → G in isoform 3. 1 PublicationAdd BLAST | 106 | |
Alternative sequenceiVSP_047036 | 64 – 112 | IYSPD…PLTAC → S in isoform 2. 1 PublicationAdd BLAST | 49 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB011169 mRNA Translation: BAA25523.1 Different initiation. AK296585 mRNA Translation: BAG59204.1 AK300034 mRNA Translation: BAG61845.1 AC012640 Genomic DNA No translation available. AC092336 Genomic DNA No translation available. CH471102 Genomic DNA Translation: EAX08065.1 CH471102 Genomic DNA Translation: EAX08066.1 BC046148 mRNA Translation: AAH46148.1 BC136461 mRNA Translation: AAI36462.1 BC136462 mRNA Translation: AAI36463.1 BC142679 mRNA Translation: AAI42680.1 BC142694 mRNA Translation: AAI42695.1 AF009301 mRNA Translation: AAB66840.1 Sequence problems. |
CCDSi | CCDS34135.1 [O60337-4] CCDS59487.1 [O60337-5] CCDS59488.1 [O60337-6] |
PIRi | T00268 |
RefSeqi | NP_001257589.1, NM_001270660.1 [O60337-5] NP_001257590.1, NM_001270661.1 [O60337-6] NP_005876.2, NM_005885.3 [O60337-4] |
Genome annotation databases
Ensembli | ENST00000274140; ENSP00000274140; ENSG00000145495 ENST00000449913; ENSP00000414643; ENSG00000145495 [O60337-5] ENST00000503788; ENSP00000425930; ENSG00000145495 [O60337-6] |
GeneIDi | 10299 |
KEGGi | hsa:10299 |
MANE-Selecti | ENST00000274140.10; ENSP00000274140.4; NM_005885.4; NP_005876.2 |
UCSCi | uc003jet.3, human [O60337-4] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB011169 mRNA Translation: BAA25523.1 Different initiation. AK296585 mRNA Translation: BAG59204.1 AK300034 mRNA Translation: BAG61845.1 AC012640 Genomic DNA No translation available. AC092336 Genomic DNA No translation available. CH471102 Genomic DNA Translation: EAX08065.1 CH471102 Genomic DNA Translation: EAX08066.1 BC046148 mRNA Translation: AAH46148.1 BC136461 mRNA Translation: AAI36462.1 BC136462 mRNA Translation: AAI36463.1 BC142679 mRNA Translation: AAI42680.1 BC142694 mRNA Translation: AAI42695.1 AF009301 mRNA Translation: AAB66840.1 Sequence problems. |
CCDSi | CCDS34135.1 [O60337-4] CCDS59487.1 [O60337-5] CCDS59488.1 [O60337-6] |
PIRi | T00268 |
RefSeqi | NP_001257589.1, NM_001270660.1 [O60337-5] NP_001257590.1, NM_001270661.1 [O60337-6] NP_005876.2, NM_005885.3 [O60337-4] |
3D structure databases
SMRi | O60337 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 115587, 51 interactors |
DIPi | DIP-56134N |
IntActi | O60337, 18 interactors |
MINTi | O60337 |
STRINGi | 9606.ENSP00000274140 |
PTM databases
iPTMneti | O60337 |
PhosphoSitePlusi | O60337 |
Genetic variation databases
BioMutai | MARCH6 |
Proteomic databases
EPDi | O60337 |
jPOSTi | O60337 |
MassIVEi | O60337 |
MaxQBi | O60337 |
PaxDbi | O60337 |
PeptideAtlasi | O60337 |
PRIDEi | O60337 |
ProteomicsDBi | 4463 49363 [O60337-4] 5070 |
Protocols and materials databases
Antibodypediai | 22463, 152 antibodies from 29 providers |
DNASUi | 10299 |
Genome annotation databases
Ensembli | ENST00000274140; ENSP00000274140; ENSG00000145495 ENST00000449913; ENSP00000414643; ENSG00000145495 [O60337-5] ENST00000503788; ENSP00000425930; ENSG00000145495 [O60337-6] |
GeneIDi | 10299 |
KEGGi | hsa:10299 |
MANE-Selecti | ENST00000274140.10; ENSP00000274140.4; NM_005885.4; NP_005876.2 |
UCSCi | uc003jet.3, human [O60337-4] |
Organism-specific databases
CTDi | 10299 |
DisGeNETi | 10299 |
GeneCardsi | MARCHF6 |
HGNCi | HGNC:30550, MARCHF6 |
HPAi | ENSG00000145495, Low tissue specificity |
MalaCardsi | MARCHF6 |
MIMi | 613297, gene 613608, phenotype |
neXtProti | NX_O60337 |
OpenTargetsi | ENSG00000145495 |
Orphaneti | 86814, Benign adult familial myoclonic epilepsy |
PharmGKBi | PA134869368 |
VEuPathDBi | HostDB:ENSG00000145495 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1609, Eukaryota |
GeneTreei | ENSGT00940000155171 |
HOGENOMi | CLU_006373_1_0_1 |
InParanoidi | O60337 |
OMAi | WLPIRIL |
OrthoDBi | 170933at2759 |
PhylomeDBi | O60337 |
TreeFami | TF105777 |
Enzyme and pathway databases
UniPathwayi | UPA00143 |
BRENDAi | 2.3.2.27, 2681 |
PathwayCommonsi | O60337 |
Reactomei | R-HSA-901032, ER Quality Control Compartment (ERQC) |
SignaLinki | O60337 |
Miscellaneous databases
BioGRID-ORCSi | 10299, 35 hits in 1041 CRISPR screens |
ChiTaRSi | MARCH6, human |
GeneWikii | MARCH6 |
GenomeRNAii | 10299 |
Pharosi | O60337, Tbio |
PROi | PR:O60337 |
RNActi | O60337, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000145495, Expressed in cerebellar vermis and 253 other tissues |
ExpressionAtlasi | O60337, baseline and differential |
Genevisiblei | O60337, HS |
Family and domain databases
Gene3Di | 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR011016, Znf_RING-CH IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF12906, RINGv, 1 hit |
SMARTi | View protein in SMART SM00744, RINGv, 1 hit |
PROSITEi | View protein in PROSITE PS51292, ZF_RING_CH, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | MARH6_HUMAN | |
Accessioni | O60337Primary (citable) accession number: O60337 Secondary accession number(s): A5PKZ4 Q86X77 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 6, 2007 |
Last sequence update: | February 6, 2007 | |
Last modified: | February 23, 2022 | |
This is version 162 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Human chromosome 5
Human chromosome 5: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PATHWAY comments
Index of metabolic and biosynthesis pathways