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Protein

Nucleolar pre-ribosomal-associated protein 1

Gene

URB1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleolar pre-ribosomal-associated protein 1
Alternative name(s):
Nucleolar protein 254 kDa
URB1 ribosome biogenesis 1 homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:URB1
Synonyms:C21orf108, KIAA0539, NOP254, NPA1
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 21

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
HostDB:ENSG00000142207.6

Human Gene Nomenclature Database

More...
HGNCi
HGNC:17344 URB1

Online Mendelian Inheritance in Man (OMIM)

More...
MIMi
608865 gene

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_O60287

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...
OpenTargetsi
ENSG00000142207

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162408676

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
URB1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000579391 – 2271Nucleolar pre-ribosomal-associated protein 1Add BLAST2271

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei17PhosphoserineBy similarity1
Modified residuei1143PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
O60287

MaxQB - The MaxQuant DataBase

More...
MaxQBi
O60287

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O60287

PeptideAtlas

More...
PeptideAtlasi
O60287

PRoteomics IDEntifications database

More...
PRIDEi
O60287

ProteomicsDB human proteome resource

More...
ProteomicsDBi
49316

2D gel databases

Two-dimensional polyacrylamide gel electrophoresis database from the Geneva University Hospital

More...
SWISS-2DPAGEi
O60287

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O60287

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O60287

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000142207 Expressed in 175 organ(s), highest expression level in endothelial cell

CleanEx database of gene expression profiles

More...
CleanExi
HS_URB1

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O60287 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA018334

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
115207, 45 interactors

Protein interaction database and analysis system

More...
IntActi
O60287, 25 interactors

Molecular INTeraction database

More...
MINTi
O60287

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000372199

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
O60287

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1791 Eukaryota
ENOG410XR9W LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000014210

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113835

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG108197

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O60287

KEGG Orthology (KO)

More...
KOi
K14861

Identification of Orthologs from Complete Genome Data

More...
OMAi
WILEILQ

Database of Orthologous Groups

More...
OrthoDBi
EOG091G007X

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O60287

TreeFam database of animal gene trees

More...
TreeFami
TF313756

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024 ARM-type_fold
IPR032436 NopRA1_C
IPR021714 Npa1_N
IPR039844 URB1

The PANTHER Classification System

More...
PANTHERi
PTHR13500 PTHR13500, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16201 NopRA1, 1 hit
PF11707 Npa1, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371 SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O60287-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVPKRKASG GQDGAASSAG AAKRARKEEL TGVRFKAQLK DPQGPGPGLE
60 70 80 90 100
AFVSAAKKLP REDVYDVVEG YIKISVECVE IFQLLSGEKR PESETMLIFQ
110 120 130 140 150
VFEAILLRTA SDLSHFHVVG TNIVKKLMNN HMKLICESLY ASGYRLARAC
160 170 180 190 200
LSLMTAMVTQ GPEAARDVCS HFDLNKKTLY TLVTKRDSKG VYDVRQAYVQ
210 220 230 240 250
FALSFLIAGD DSTIVQVLEV KEFIPCIFSS GIKEDRISTI NILLSTLKTK
260 270 280 290 300
VVHNKNITKT QKVRFFTGQL LNHIASLYNW NGITDVNPEN VKVSAEEAGK
310 320 330 340 350
TMVRELVHNF LMDLCCSLKH GINFYDASLG TFGRGGNLTL LHFLLGLKTA
360 370 380 390 400
ADDDLVADLV VNILKVCPDL LNKYFKEVTF SFIPRAKSTW LNNIKLLNKI
410 420 430 440 450
YEAQPEISRA FQTREFIPLP RLLAMVMVTT VPLVCNKSMF TQALNLDSTS
460 470 480 490 500
VRHTALSLIS VILKRALKTV DHCLNKEVWQ ESGVYTAVMM EEFVQLFREA
510 520 530 540 550
LSKILPDLNT VVWVWQSLKK QETKQDDKKG QKRSDGPPAA CDAHQCDDAE
560 570 580 590 600
TILLKAVLLQ VICLYQKVVP HVVMQYNFDF SKLLKGVISE QGLREEVPPI
610 620 630 640 650
LQHHMLKVAL ELPASKFLWL KAQEGPDAEI IGGERSVFYL LMKMFVTSSH
660 670 680 690 700
LQLKSLTKLL IMKILRDTGV FEHTWKELEL WLEHLENTME EDKETVIQFL
710 720 730 740 750
ERILLTLVAN PYSYTDKASD FVQEASMLQA TMTKQEADDM SIPISHIDDV
760 770 780 790 800
LDMVDVLVEG SEGLDEEIGF TLSEDMILLT FPFSAVVPAA LEARNKLLLG
810 820 830 840 850
TGNEAAENVV TYLTAVLTDL LHTQRDPLAL CLLLQAYDKL EPPCLVPCCQ
860 870 880 890 900
QLSRFNRYYS LWIPEQAREA WLLQAQGSPS PPALPLASSF TALLQAAYES
910 920 930 940 950
QALRDEHIQV QLQATMPHLS MQQVLLAAKQ VLLYLRSTVE NFGQLGRSVG
960 970 980 990 1000
PPLLQLFLDL LRRLVVHCEQ LDAQNQQRCE AARAEADLFL DMESVASLEL
1010 1020 1030 1040 1050
ANDQTLEEVL VAILRHPTLE GWFLALEQQA LPPHTLSPVL VKLLATHFSA
1060 1070 1080 1090 1100
GVLQLLAASA PILQNIGQLG LLARYSEAIT QSVLKELQNR RAGPATSPPK
1110 1120 1130 1140 1150
TPPQLEALQE LHPYMEGAQL REVTLALLSL PETHLVTQQP TKSPGKERHL
1160 1170 1180 1190 1200
NALGKTLVQL LTCSPQDQLQ SGELLWSSEY VRGLGALLPT LAVDELDTVL
1210 1220 1230 1240 1250
LHTLQRDPVL APAVGADLLD YCLARRTQAA LSIAALLLQE SCTHLLWFEQ
1260 1270 1280 1290 1300
WCLQAGPGLG LQGDLDDFLP LIHVYLQCRT RSHFTRPAGV SSAVIPVLRK
1310 1320 1330 1340 1350
TLWRQLQSRL LSTDSPPASG LYQEILAQLV PFARAKDLSV LMDRLPSLLH
1360 1370 1380 1390 1400
TPSSHKRWIV ADSISAALEG SAEELCAWRR TLLESCVKWL IVSFSGGQQD
1410 1420 1430 1440 1450
DDNTQNQEKE MLLRLNALLH ALNEVDPGDW QKFVKKGLKF RYQDHTFLKM
1460 1470 1480 1490 1500
LLTAVQLLYS PESSVRTKLI QLPVVYVMLM QHSLFLPTLL TSDGEESPDS
1510 1520 1530 1540 1550
QVKEALVDLM LTVVEMCPSV CESSHFAVLL GAYGATLSVL DQKILLLLRA
1560 1570 1580 1590 1600
YEQNKLSLIN FRVLLWGPAA VEHHKTCRSL GRSLWQQPSV GDILRLLDRD
1610 1620 1630 1640 1650
RMMQTILHFP QNRRLLPPED TQELIFKDKS RVDLDGLYDP CFLLQLFSEL
1660 1670 1680 1690 1700
TRPEFVVDCR KFLDSNALGL TVTALSSYDP QMRAIAYHVL AAYYSHLEGA
1710 1720 1730 1740 1750
RFQEQSQLLY LLDVVRNGIR TQDMRLTFTL ALFIAKAALQ ILKPEEHMYL
1760 1770 1780 1790 1800
KVSNFLLSHE YLNMDKVPGF YQFFYSSDFE QKTEQKWVFG VLRQGIRDKQ
1810 1820 1830 1840 1850
CYELCARRGI FHIILSFFHS PLCDEAAQNW ILEILQNAAQ VARSAYEIIR
1860 1870 1880 1890 1900
DYSLLTWILH ILESKFLETP LLSNVISLLH TLWVTNLGDK AVEWESQRLC
1910 1920 1930 1940 1950
QPSSQEPAKR LALHLVNEFL YVLIVLMKHL RPTLAPVQLT NFFGTLDSVL
1960 1970 1980 1990 2000
RYRATVIQAF RDMNRFTVNE TVLSTKDVLV LLHKWSLIER DLKLQEDLRA
2010 2020 2030 2040 2050
AIEKAQAREL MKMLKDKNKP VMPARAKGPR GRKRRPGEAE EMADPELMAS
2060 2070 2080 2090 2100
TLETCKGLLR SILTYWRPVI PGPDPTQEPV DSASPESDAP GPVYAAASLA
2110 2120 2130 2140 2150
VSWVLRSVAE HPLSRAEAAG LIGWLKSHIL PHPVVVADLL KDSAVRSSIF
2160 2170 2180 2190 2200
RLYSRLCGAE GLAGPVQEVA CLFNTVMLQL VAAQGRAGSP FHPAMEALSL
2210 2220 2230 2240 2250
SSLSEKDEAT QASAAFLVSL YIKDIWLGAQ RPDTLLTHVR MVCEAADDAP
2260 2270
SSEEEAIVVL CKDAASAASD A
Length:2,271
Mass (Da):254,389
Last modified:November 24, 2009 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i1217E7A724E816D8
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti368P → S in BAA25465 (PubMed:9628581).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_0605861791V → L2 PublicationsCorresponds to variant dbSNP:rs3761342Ensembl.1
Natural variantiVAR_0597052071P → R. Corresponds to variant dbSNP:rs762225Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP000266 Genomic DNA No translation available.
AP000267 Genomic DNA No translation available.
AP000268 Genomic DNA No translation available.
AP000269 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX09876.1
CH471079 Genomic DNA Translation: EAX09877.1
CT001610 mRNA No translation available.
AF231919 mRNA Translation: AAF72943.1
AB011111 mRNA Translation: BAA25465.2
AF432264 mRNA Translation: AAL28110.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS46645.1

Protein sequence database of the Protein Information Resource

More...
PIRi
T00269

NCBI Reference Sequences

More...
RefSeqi
NP_055640.2, NM_014825.2

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Hs.473611

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000382751; ENSP00000372199; ENSG00000142207

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
9875

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:9875

UCSC genome browser

More...
UCSCi
uc002ypn.3 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP000266 Genomic DNA No translation available.
AP000267 Genomic DNA No translation available.
AP000268 Genomic DNA No translation available.
AP000269 Genomic DNA No translation available.
CH471079 Genomic DNA Translation: EAX09876.1
CH471079 Genomic DNA Translation: EAX09877.1
CT001610 mRNA No translation available.
AF231919 mRNA Translation: AAF72943.1
AB011111 mRNA Translation: BAA25465.2
AF432264 mRNA Translation: AAL28110.1
CCDSiCCDS46645.1
PIRiT00269
RefSeqiNP_055640.2, NM_014825.2
UniGeneiHs.473611

3D structure databases

ProteinModelPortaliO60287
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi115207, 45 interactors
IntActiO60287, 25 interactors
MINTiO60287
STRINGi9606.ENSP00000372199

PTM databases

iPTMnetiO60287
PhosphoSitePlusiO60287

Polymorphism and mutation databases

BioMutaiURB1

2D gel databases

SWISS-2DPAGEiO60287

Proteomic databases

EPDiO60287
MaxQBiO60287
PaxDbiO60287
PeptideAtlasiO60287
PRIDEiO60287
ProteomicsDBi49316

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000382751; ENSP00000372199; ENSG00000142207
GeneIDi9875
KEGGihsa:9875
UCSCiuc002ypn.3 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
9875
EuPathDBiHostDB:ENSG00000142207.6

GeneCards: human genes, protein and diseases

More...
GeneCardsi
URB1

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0016060
HGNCiHGNC:17344 URB1
HPAiHPA018334
MIMi608865 gene
neXtProtiNX_O60287
OpenTargetsiENSG00000142207
PharmGKBiPA162408676

Human Unidentified Gene-Encoded large proteins database

More...
HUGEi
Search...

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiKOG1791 Eukaryota
ENOG410XR9W LUCA
GeneTreeiENSGT00390000014210
HOGENOMiHOG000113835
HOVERGENiHBG108197
InParanoidiO60287
KOiK14861
OMAiWILEILQ
OrthoDBiEOG091G007X
PhylomeDBiO60287
TreeFamiTF313756

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
URB1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
9875

Protein Ontology

More...
PROi
PR:O60287

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSG00000142207 Expressed in 175 organ(s), highest expression level in endothelial cell
CleanExiHS_URB1
GenevisibleiO60287 HS

Family and domain databases

InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR032436 NopRA1_C
IPR021714 Npa1_N
IPR039844 URB1
PANTHERiPTHR13500 PTHR13500, 1 hit
PfamiView protein in Pfam
PF16201 NopRA1, 1 hit
PF11707 Npa1, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNPA1P_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O60287
Secondary accession number(s): D3DSE5, Q96NX1, Q9NYQ1
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: November 24, 2009
Last modified: November 7, 2018
This is version 148 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 21
    Human chromosome 21: entries, gene names and cross-references to MIM
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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