UniProtKB - O60242 (AGRB3_HUMAN)
Adhesion G protein-coupled receptor B3
ADGRB3
Functioni
Receptor that plays a role in the regulation of synaptogenesis and dendritic spine formation at least partly via interaction with ELMO1 and RAC1 activity (By similarity).
Promotes myoblast fusion through ELMO/DOCK1 (PubMed:24567399).
By similarity1 PublicationMiscellaneous
GO - Molecular functioni
- G protein-coupled receptor activity Source: GO_Central
- GTPase activator activity Source: UniProtKB
GO - Biological processi
- adenylate cyclase-activating G protein-coupled receptor signaling pathway Source: GO_Central
- cell surface receptor signaling pathway Source: InterPro
- G protein-coupled receptor signaling pathway Source: GDB
- maintenance of synapse structure Source: Ensembl
- motor learning Source: Ensembl
- myoblast fusion Source: UniProtKB
- negative regulation of angiogenesis Source: InterPro
- neuron remodeling Source: GO_Central
- positive regulation of synapse assembly Source: Ensembl
- regulation of dendrite morphogenesis Source: UniProtKB
Keywordsi
Molecular function | G-protein coupled receptor, Receptor, Transducer |
Enzyme and pathway databases
PathwayCommonsi | O60242 |
SignaLinki | O60242 |
Protein family/group databases
MEROPSi | P02.027 |
TCDBi | 9.A.14.6.7, the g-protein-coupled receptor (gpcr) family |
Names & Taxonomyi
Protein namesi | Recommended name: Adhesion G protein-coupled receptor B31 PublicationAlternative name(s): Brain-specific angiogenesis inhibitor 3 |
Gene namesi | |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:945, ADGRB3 |
MIMi | 602684, gene |
neXtProti | NX_O60242 |
VEuPathDBi | HostDB:ENSG00000135298 |
Subcellular locationi
Plasma membrane
- Cell membrane 2 Publications; Multi-pass membrane protein Sequence analysis
Extracellular region or secreted
- synaptic cleft Source: GO_Central
Plasma Membrane
- integral component of plasma membrane Source: GO_Central
- plasma membrane Source: UniProtKB
Other locations
- integral component of membrane Source: GDB
- postsynapse Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 25 – 880 | ExtracellularCuratedAdd BLAST | 856 | |
Transmembranei | 881 – 901 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 902 – 910 | CytoplasmicCurated | 9 | |
Transmembranei | 911 – 931 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 932 – 939 | ExtracellularCurated | 8 | |
Transmembranei | 940 – 960 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 961 – 981 | CytoplasmicCuratedAdd BLAST | 21 | |
Transmembranei | 982 – 1002 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 1003 – 1023 | ExtracellularCuratedAdd BLAST | 21 | |
Transmembranei | 1024 – 1044 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 1045 – 1098 | CytoplasmicCuratedAdd BLAST | 54 | |
Transmembranei | 1099 – 1119 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 1120 – 1125 | ExtracellularCurated | 6 | |
Transmembranei | 1126 – 1146 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Topological domaini | 1147 – 1522 | CytoplasmicCuratedAdd BLAST | 376 |
Keywords - Cellular componenti
Cell membrane, MembranePathology & Biotechi
Organism-specific databases
DisGeNETi | 577 |
OpenTargetsi | ENSG00000135298 |
PharmGKBi | PA25249 |
Miscellaneous databases
Pharosi | O60242, Tbio |
Genetic variation databases
BioMutai | ADGRB3 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 24 | Sequence analysisAdd BLAST | 24 | |
ChainiPRO_0000012865 | 25 – 1522 | Adhesion G protein-coupled receptor B3Add BLAST | 1498 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 30 ↔ 55 | PROSITE-ProRule annotation | ||
Glycosylationi | 51 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 54 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 82 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 105 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 241 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 303 ↔ 336 | PROSITE-ProRule annotation | ||
Disulfide bondi | 307 ↔ 342 | PROSITE-ProRule annotation | ||
Disulfide bondi | 318 ↔ 326 | PROSITE-ProRule annotation | ||
Glycosylationi | 337 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 357 ↔ 392 | PROSITE-ProRule annotation | ||
Disulfide bondi | 361 ↔ 397 | PROSITE-ProRule annotation | ||
Disulfide bondi | 372 ↔ 382 | PROSITE-ProRule annotation | ||
Disulfide bondi | 412 ↔ 447 | PROSITE-ProRule annotation | ||
Disulfide bondi | 416 ↔ 452 | PROSITE-ProRule annotation | ||
Glycosylationi | 418 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 427 ↔ 437 | PROSITE-ProRule annotation | ||
Disulfide bondi | 467 ↔ 502 | PROSITE-ProRule annotation | ||
Disulfide bondi | 471 ↔ 507 | PROSITE-ProRule annotation | ||
Disulfide bondi | 482 ↔ 492 | PROSITE-ProRule annotation | ||
Disulfide bondi | 514 ↔ 549 | 1 Publication | ||
Disulfide bondi | 537 ↔ 567 | 1 Publication | ||
Glycosylationi | 540 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Modified residuei | 619 | PhosphoserineCombined sources | 1 | |
Glycosylationi | 625 | N-linked (GlcNAc...) asparagine1 Publication | 1 | |
Glycosylationi | 779 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 812 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 819 ↔ 851 | 1 Publication | ||
Glycosylationi | 828 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 839 ↔ 853 | 1 Publication | ||
Glycosylationi | 937 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Modified residuei | 1220 | PhosphoserineBy similarity | 1 | |
Modified residuei | 1411 | PhosphoserineBy similarity | 1 |
Post-translational modificationi
Keywords - PTMi
Disulfide bond, Glycoprotein, PhosphoproteinProteomic databases
MassIVEi | O60242 |
PaxDbi | O60242 |
PeptideAtlasi | O60242 |
PRIDEi | O60242 |
ProteomicsDBi | 49275 [O60242-1] 6341 |
PTM databases
GlyConnecti | 2016, 1 N-Linked glycan (1 site) |
GlyGeni | O60242, 14 sites, 2 N-linked glycans (1 site) |
iPTMneti | O60242 |
PhosphoSitePlusi | O60242 |
Expressioni
Tissue specificityi
Gene expression databases
Bgeei | ENSG00000135298, Expressed in middle temporal gyrus and 156 other tissues |
ExpressionAtlasi | O60242, baseline and differential |
Genevisiblei | O60242, HS |
Organism-specific databases
HPAi | ENSG00000135298, Group enriched (brain, pituitary gland) |
Interactioni
Subunit structurei
Binary interactionsi
O60242
Protein-protein interaction databases
BioGRIDi | 107053, 11 interactors |
DIPi | DIP-56121N |
IntActi | O60242, 10 interactors |
STRINGi | 9606.ENSP00000359630 |
Miscellaneous databases
RNActi | O60242, protein |
Structurei
Secondary structure
3D structure databases
SMRi | O60242 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 30 – 159 | CUBPROSITE-ProRule annotationAdd BLAST | 130 | |
Domaini | 291 – 343 | TSP type-1 1PROSITE-ProRule annotationAdd BLAST | 53 | |
Domaini | 345 – 398 | TSP type-1 2PROSITE-ProRule annotationAdd BLAST | 54 | |
Domaini | 400 – 453 | TSP type-1 3PROSITE-ProRule annotationAdd BLAST | 54 | |
Domaini | 455 – 508 | TSP type-1 4PROSITE-ProRule annotationAdd BLAST | 54 | |
Domaini | 816 – 868 | GPSPROSITE-ProRule annotationAdd BLAST | 53 |
Sequence similaritiesi
Keywords - Domaini
Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG502QRKJ, Eukaryota |
GeneTreei | ENSGT00940000155081 |
HOGENOMi | CLU_003751_1_0_1 |
InParanoidi | O60242 |
OMAi | DIACRSX |
OrthoDBi | 27621at2759 |
PhylomeDBi | O60242 |
TreeFami | TF331634 |
Family and domain databases
Gene3Di | 2.20.100.10, 4 hits 4.10.1240.10, 1 hit |
InterProi | View protein in InterPro IPR043838, AGRB_N IPR000859, CUB_dom IPR032471, GAIN_dom_N IPR017981, GPCR_2-like IPR008077, GPCR_2_brain_angio_inhib IPR036445, GPCR_2_extracell_dom_sf IPR001879, GPCR_2_extracellular_dom IPR000832, GPCR_2_secretin-like IPR017983, GPCR_2_secretin-like_CS IPR000203, GPS IPR000884, TSP1_rpt IPR036383, TSP1_rpt_sf |
Pfami | View protein in Pfam PF00002, 7tm_2, 1 hit PF19188, AGRB_N, 1 hit PF16489, GAIN, 1 hit PF01825, GPS, 1 hit PF02793, HRM, 1 hit PF00090, TSP_1, 4 hits |
PRINTSi | PR01694, BAIPRECURSOR PR00249, GPCRSECRETIN |
SMARTi | View protein in SMART SM00303, GPS, 1 hit SM00008, HormR, 1 hit SM00209, TSP1, 4 hits |
SUPFAMi | SSF82895, SSF82895, 4 hits |
PROSITEi | View protein in PROSITE PS01180, CUB, 1 hit PS00650, G_PROTEIN_RECEP_F2_2, 1 hit PS50227, G_PROTEIN_RECEP_F2_3, 1 hit PS50261, G_PROTEIN_RECEP_F2_4, 1 hit PS50221, GPS, 1 hit PS50092, TSP1, 4 hits |
s (2+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 2 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 2 described isoforms and 4 potential isoforms that are computationally mapped.Show allAlign All
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MKAVRNLLIY IFSTYLLVMF GFNAAQDFWC STLVKGVIYG SYSVSEMFPK
60 70 80 90 100
NFTNCTWTLE NPDPTKYSIY LKFSKKDLSC SNFSLLAYQF DHFSHEKIKD
110 120 130 140 150
LLRKNHSIMQ LCNSKNAFVF LQYDKNFIQI RRVFPTNFPG LQKKGEEDQK
160 170 180 190 200
SFFEFLVLNK VSPSQFGCHV LCTWLESCLK SENGRTESCG IMYTKCTCPQ
210 220 230 240 250
HLGEWGIDDQ SLILLNNVVL PLNEQTEGCL TQELQTTQVC NLTREAKRPP
260 270 280 290 300
KEEFGMMGDH TIKSQRPRSV HEKRVPQEQA DAAKFMAQTG ESGVEEWSQW
310 320 330 340 350
STCSVTCGQG SQVRTRTCVS PYGTHCSGPL RESRVCNNTA LCPVHGVWEE
360 370 380 390 400
WSPWSLCSFT CGRGQRTRTR SCTPPQYGGR PCEGPETHHK PCNIALCPVD
410 420 430 440 450
GQWQEWSSWS QCSVTCSNGT QQRSRQCTAA AHGGSECRGP WAESRECYNP
460 470 480 490 500
ECTANGQWNQ WGHWSGCSKS CDGGWERRIR TCQGAVITGQ QCEGTGEEVR
510 520 530 540 550
RCNEQRCPAP YEICPEDYLM SMVWKRTPAG DLAFNQCPLN ATGTTSRRCS
560 570 580 590 600
LSLHGVAFWE QPSFARCISN EYRHLQHSIK EHLAKGQRML AGDGMSQVTK
610 620 630 640 650
TLLDLTQRKN FYAGDLLMSV EILRNVTDTF KRASYIPASD GVQNFFQIVS
660 670 680 690 700
NLLDEENKEK WEDAQQIYPG SIELMQVIED FIHIVGMGMM DFQNSYLMTG
710 720 730 740 750
NVVASIQKLP AASVLTDINF PMKGRKGMVD WARNSEDRVV IPKSIFTPVS
760 770 780 790 800
SKELDESSVF VLGAVLYKNL DLILPTLRNY TVINSKIIVV TIRPEPKTTD
810 820 830 840 850
SFLEIELAHL ANGTLNPYCV LWDDSKTNES LGTWSTQGCK TVLTDASHTK
860 870 880 890 900
CLCDRLSTFA ILAQQPREII MESSGTPSVT LIVGSGLSCL ALITLAVVYA
910 920 930 940 950
ALWRYIRSER SIILINFCLS IISSNILILV GQTQTHNKSI CTTTTAFLHF
960 970 980 990 1000
FFLASFCWVL TEAWQSYMAV TGKIRTRLIR KRFLCLGWGL PALVVATSVG
1010 1020 1030 1040 1050
FTRTKGYGTD HYCWLSLEGG LLYAFVGPAA AVVLVNMVIG ILVFNKLVSR
1060 1070 1080 1090 1100
DGILDKKLKH RAGQMSEPHS GLTLKCAKCG VVSTTALSAT TASNAMASLW
1110 1120 1130 1140 1150
SSCVVLPLLA LTWMSAVLAM TDKRSILFQI LFAVFDSLQG FVIVMVHCIL
1160 1170 1180 1190 1200
RREVQDAFRC RLRNCQDPIN ADSSSSFPNG HAQIMTDFEK DVDIACRSVL
1210 1220 1230 1240 1250
HKDIGPCRAA TITGTLSRIS LNDDEEEKGT NPEGLSYSTL PGNVISKVII
1260 1270 1280 1290 1300
QQPTGLHMPM SMNELSNPCL KKENSELRRT VYLCTDDNLR GADMDIVHPQ
1310 1320 1330 1340 1350
ERMMESDYIV MPRSSVNNQP SMKEESKMNI GMETLPHERL LHYKVNPEFN
1360 1370 1380 1390 1400
MNPPVMDQFN MNLEQHLAPQ EHMQNLPFEP RTAVKNFMAS ELDDNAGLSR
1410 1420 1430 1440 1450
SETGSTISMS SLERRKSRYS DLDFEKVMHT RKRHMELFQE LNQKFQTLDR
1460 1470 1480 1490 1500
FRDIPNTSSM ENPAPNKNPW DTFKNPSEYP HYTTINVLDT EAKDALELRP
1510 1520
AEWEKCLNLP LDVQEGDFQT EV
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketJ3KMY8 | J3KMY8_HUMAN | Adhesion G protein-coupled receptor... | ADGRB3 | 728 | Annotation score: | ||
S4R307 | S4R307_HUMAN | Adhesion G protein-coupled receptor... | ADGRB3 | 145 | Annotation score: | ||
S4R3D0 | S4R3D0_HUMAN | Adhesion G protein-coupled receptor... | ADGRB3 | 68 | Annotation score: | ||
A0A804HJR2 | A0A804HJR2_HUMAN | Adhesion G protein-coupled receptor... | ADGRB3 | 1,063 | Annotation score: |
Sequence cautioni
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_046525 | 503 | N → S3 PublicationsCorresponds to variant dbSNP:rs1932618Ensembl. | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_056939 | 1 – 1036 | Missing in isoform 2. 1 PublicationAdd BLAST | 1036 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB005299 mRNA Translation: BAA25363.1 AB011122 mRNA Translation: BAA25476.2 Different initiation. AK293560 mRNA Translation: BAH11536.1 AL035469 Genomic DNA No translation available. AL078598 Genomic DNA No translation available. AL589875 Genomic DNA No translation available. AL133378 Genomic DNA No translation available. AL158051 Genomic DNA No translation available. AL160401 Genomic DNA No translation available. AL356117 Genomic DNA No translation available. AL359714 Genomic DNA No translation available. AL391807 Genomic DNA No translation available. CH471051 Genomic DNA Translation: EAW48837.1 BC111720 mRNA Translation: AAI11721.1 |
CCDSi | CCDS4968.1 [O60242-1] |
PIRi | T00028 T00326 |
RefSeqi | NP_001695.1, NM_001704.2 [O60242-1] XP_005248809.1, XM_005248752.2 |
Genome annotation databases
Ensembli | ENST00000370598; ENSP00000359630; ENSG00000135298 ENST00000546190; ENSP00000441821; ENSG00000135298 |
GeneIDi | 577 |
KEGGi | hsa:577 |
MANE-Selecti | ENST00000370598.6; ENSP00000359630.1; NM_001704.3; NP_001695.2 |
UCSCi | uc003pev.5, human [O60242-1] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AB005299 mRNA Translation: BAA25363.1 AB011122 mRNA Translation: BAA25476.2 Different initiation. AK293560 mRNA Translation: BAH11536.1 AL035469 Genomic DNA No translation available. AL078598 Genomic DNA No translation available. AL589875 Genomic DNA No translation available. AL133378 Genomic DNA No translation available. AL158051 Genomic DNA No translation available. AL160401 Genomic DNA No translation available. AL356117 Genomic DNA No translation available. AL359714 Genomic DNA No translation available. AL391807 Genomic DNA No translation available. CH471051 Genomic DNA Translation: EAW48837.1 BC111720 mRNA Translation: AAI11721.1 |
CCDSi | CCDS4968.1 [O60242-1] |
PIRi | T00028 T00326 |
RefSeqi | NP_001695.1, NM_001704.2 [O60242-1] XP_005248809.1, XM_005248752.2 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
4DLO | X-ray | 2.30 | A/B | 498-868 | [»] | |
SMRi | O60242 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 107053, 11 interactors |
DIPi | DIP-56121N |
IntActi | O60242, 10 interactors |
STRINGi | 9606.ENSP00000359630 |
Protein family/group databases
MEROPSi | P02.027 |
TCDBi | 9.A.14.6.7, the g-protein-coupled receptor (gpcr) family |
GPCRDBi | Search... |
PTM databases
GlyConnecti | 2016, 1 N-Linked glycan (1 site) |
GlyGeni | O60242, 14 sites, 2 N-linked glycans (1 site) |
iPTMneti | O60242 |
PhosphoSitePlusi | O60242 |
Genetic variation databases
BioMutai | ADGRB3 |
Proteomic databases
MassIVEi | O60242 |
PaxDbi | O60242 |
PeptideAtlasi | O60242 |
PRIDEi | O60242 |
ProteomicsDBi | 49275 [O60242-1] 6341 |
Protocols and materials databases
Antibodypediai | 2938, 239 antibodies from 32 providers |
DNASUi | 577 |
Genome annotation databases
Ensembli | ENST00000370598; ENSP00000359630; ENSG00000135298 ENST00000546190; ENSP00000441821; ENSG00000135298 |
GeneIDi | 577 |
KEGGi | hsa:577 |
MANE-Selecti | ENST00000370598.6; ENSP00000359630.1; NM_001704.3; NP_001695.2 |
UCSCi | uc003pev.5, human [O60242-1] |
Organism-specific databases
CTDi | 577 |
DisGeNETi | 577 |
GeneCardsi | ADGRB3 |
HGNCi | HGNC:945, ADGRB3 |
HPAi | ENSG00000135298, Group enriched (brain, pituitary gland) |
MIMi | 602684, gene |
neXtProti | NX_O60242 |
OpenTargetsi | ENSG00000135298 |
PharmGKBi | PA25249 |
VEuPathDBi | HostDB:ENSG00000135298 |
HUGEi | Search... |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | ENOG502QRKJ, Eukaryota |
GeneTreei | ENSGT00940000155081 |
HOGENOMi | CLU_003751_1_0_1 |
InParanoidi | O60242 |
OMAi | DIACRSX |
OrthoDBi | 27621at2759 |
PhylomeDBi | O60242 |
TreeFami | TF331634 |
Enzyme and pathway databases
PathwayCommonsi | O60242 |
SignaLinki | O60242 |
Miscellaneous databases
BioGRID-ORCSi | 577, 7 hits in 1040 CRISPR screens |
ChiTaRSi | ADGRB3, human |
GeneWikii | Brain-specific_angiogenesis_inhibitor_3 |
GenomeRNAii | 577 |
Pharosi | O60242, Tbio |
PROi | PR:O60242 |
RNActi | O60242, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000135298, Expressed in middle temporal gyrus and 156 other tissues |
ExpressionAtlasi | O60242, baseline and differential |
Genevisiblei | O60242, HS |
Family and domain databases
Gene3Di | 2.20.100.10, 4 hits 4.10.1240.10, 1 hit |
InterProi | View protein in InterPro IPR043838, AGRB_N IPR000859, CUB_dom IPR032471, GAIN_dom_N IPR017981, GPCR_2-like IPR008077, GPCR_2_brain_angio_inhib IPR036445, GPCR_2_extracell_dom_sf IPR001879, GPCR_2_extracellular_dom IPR000832, GPCR_2_secretin-like IPR017983, GPCR_2_secretin-like_CS IPR000203, GPS IPR000884, TSP1_rpt IPR036383, TSP1_rpt_sf |
Pfami | View protein in Pfam PF00002, 7tm_2, 1 hit PF19188, AGRB_N, 1 hit PF16489, GAIN, 1 hit PF01825, GPS, 1 hit PF02793, HRM, 1 hit PF00090, TSP_1, 4 hits |
PRINTSi | PR01694, BAIPRECURSOR PR00249, GPCRSECRETIN |
SMARTi | View protein in SMART SM00303, GPS, 1 hit SM00008, HormR, 1 hit SM00209, TSP1, 4 hits |
SUPFAMi | SSF82895, SSF82895, 4 hits |
PROSITEi | View protein in PROSITE PS01180, CUB, 1 hit PS00650, G_PROTEIN_RECEP_F2_2, 1 hit PS50227, G_PROTEIN_RECEP_F2_3, 1 hit PS50261, G_PROTEIN_RECEP_F2_4, 1 hit PS50221, GPS, 1 hit PS50092, TSP1, 4 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | AGRB3_HUMAN | |
Accessioni | O60242Primary (citable) accession number: O60242 Secondary accession number(s): B7Z1K0 Q9BX54 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | December 1, 2000 |
Last sequence update: | November 2, 2010 | |
Last modified: | February 23, 2022 | |
This is version 187 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- 7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries - Human chromosome 6
Human chromosome 6: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families