UniProtKB - O60142 (PPR2_SCHPO)
Protein
Pentatricopeptide repeat-containing protein 2, mitochondrial
Gene
ppr2
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
Mitochondrial RNA-binding protein that acts as a general translation factor.1 Publication
GO - Biological processi
- mitochondrial gene expression Source: PomBase
- regulation of translation Source: UniProtKB-KW
- translation Source: UniProtKB-KW
Keywordsi
Molecular function | Activator |
Biological process | Protein biosynthesis, Translation regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Pentatricopeptide repeat-containing protein 2, mitochondrial |
Gene namesi | Name:ppr2 ORF Names:SPBC18H10.11c |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC18H10.11c, ppr2 |
VEuPathDBi | FungiDB:SPBC18H10.11c |
Subcellular locationi
Mitochondrion
- Mitochondrion 2 Publications
Mitochondrion
- mitochondrial matrix Source: PomBase
- mitochondrion Source: PomBase
Keywords - Cellular componenti
MitochondrionPathology & Biotechi
Disruption phenotypei
Impairs growth on galactose.1 Publication
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transit peptidei | 1 – 33 | MitochondrionSequence analysisAdd BLAST | 33 | |
ChainiPRO_0000316604 | 34 – 432 | Pentatricopeptide repeat-containing protein 2, mitochondrialAdd BLAST | 399 |
Proteomic databases
MaxQBi | O60142 |
PaxDbi | O60142 |
PRIDEi | O60142 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 277316, 86 interactors |
STRINGi | 4896.SPBC18H10.11c.1 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Repeati | 108 – 142 | PPR 1Add BLAST | 35 | |
Repeati | 143 – 179 | PPR 2Add BLAST | 37 | |
Repeati | 360 – 394 | PPR 3Add BLAST | 35 | |
Repeati | 395 – 429 | PPR 4Add BLAST | 35 |
Keywords - Domaini
Repeat, Transit peptidePhylogenomic databases
eggNOGi | ENOG502QSY4, Eukaryota |
HOGENOMi | CLU_625787_0_0_1 |
InParanoidi | O60142 |
OMAi | IHEDLLC |
PhylomeDBi | O60142 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR002885, Pentatricopeptide_repeat IPR011990, TPR-like_helical_dom_sf |
Pfami | View protein in Pfam PF13041, PPR_2, 1 hit |
TIGRFAMsi | TIGR00756, PPR, 1 hit |
PROSITEi | View protein in PROSITE PS51375, PPR, 2 hits |
i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
O60142-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MQFIKRTFPR RAFVDLLLNR FCLREFATTY SVSVSNARKL VRKRLLIADA
60 70 80 90 100
LKFKEQVNNL NEFRNKKTKS SLIRNDGFKL AKNVSSLLQK ESLEKALHLL
110 120 130 140 150
YERSNAKKTV AYNLVLQYHL AKGHYNAAWS LYNDMKKRQQ KPSDHTYSIL
160 170 180 190 200
LKGFCDAIEK NKQGNFSKLR EYSEKVTASA LKESNNVTSN LHHIRIISKC
210 220 230 240 250
SLKLKSMVLV SMIIPSIKQT LDFYSGSQIL RLLNDFSMFN PEQREEVLKM
260 270 280 290 300
GTNLWNYFVL ECQKKGIAVD ESLICSFVKL LATSNSPQVR NVGLNILTKV
310 320 330 340 350
MGLEYQIFED SNLRYPLPPY CDCTSRSLVT ALQVIRQIQN GDLLARYWKY
360 370 380 390 400
FEESHKFDLN LQVYHEKLRN LVQQGQAAEC LNTIKRMSHN GPFPTQQTFL
410 420 430
IVLSLCKRPK FYSYTKSFLD LAKKLNVPVE AT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA18408.1 |
PIRi | T39775 |
RefSeqi | NP_595735.1, NM_001021633.2 |
Genome annotation databases
EnsemblFungii | SPBC18H10.11c.1; SPBC18H10.11c.1:pep; SPBC18H10.11c |
GeneIDi | 2540797 |
KEGGi | spo:SPBC18H10.11c |
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU329671 Genomic DNA Translation: CAA18408.1 |
PIRi | T39775 |
RefSeqi | NP_595735.1, NM_001021633.2 |
3D structure databases
SMRi | O60142 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 277316, 86 interactors |
STRINGi | 4896.SPBC18H10.11c.1 |
Proteomic databases
MaxQBi | O60142 |
PaxDbi | O60142 |
PRIDEi | O60142 |
Genome annotation databases
EnsemblFungii | SPBC18H10.11c.1; SPBC18H10.11c.1:pep; SPBC18H10.11c |
GeneIDi | 2540797 |
KEGGi | spo:SPBC18H10.11c |
Organism-specific databases
PomBasei | SPBC18H10.11c, ppr2 |
VEuPathDBi | FungiDB:SPBC18H10.11c |
Phylogenomic databases
eggNOGi | ENOG502QSY4, Eukaryota |
HOGENOMi | CLU_625787_0_0_1 |
InParanoidi | O60142 |
OMAi | IHEDLLC |
PhylomeDBi | O60142 |
Miscellaneous databases
PROi | PR:O60142 |
Family and domain databases
Gene3Di | 1.25.40.10, 1 hit |
InterProi | View protein in InterPro IPR002885, Pentatricopeptide_repeat IPR011990, TPR-like_helical_dom_sf |
Pfami | View protein in Pfam PF13041, PPR_2, 1 hit |
TIGRFAMsi | TIGR00756, PPR, 1 hit |
PROSITEi | View protein in PROSITE PS51375, PPR, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | PPR2_SCHPO | |
Accessioni | O60142Primary (citable) accession number: O60142 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | February 5, 2008 |
Last sequence update: | August 1, 1998 | |
Last modified: | April 7, 2021 | |
This is version 99 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names