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UniProtKB - O59932 (GHT4_SCHPO)
Protein
High-affinity hexose transporter ght4
Gene
ght4
Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Functioni
GO - Molecular functioni
- carbohydrate:proton symporter activity Source: GO_Central
GO - Biological processi
- carbohydrate transport Source: GO_Central
Keywordsi
Biological process | Sugar transport, Transport |
Names & Taxonomyi
Protein namesi | Recommended name: High-affinity hexose transporter ght4Short name: Hexose transporter 4 |
Gene namesi | Name:ght4 ORF Names:SPBC1683.08 |
Organismi | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) |
Taxonomic identifieri | 284812 [NCBI] |
Taxonomic lineagei | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › |
Proteomesi |
|
Organism-specific databases
PomBasei | SPBC1683.08, ght4 |
VEuPathDBi | FungiDB:SPBC1683.08 |
Subcellular locationi
Other locations
Plasma Membrane
- integral component of plasma membrane Source: PomBase
- plasma membrane Source: PomBase
- plasma membrane of cell tip Source: PomBase
Other locations
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 9 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 10 – 30 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 31 – 58 | ExtracellularSequence analysisAdd BLAST | 28 | |
Transmembranei | 59 – 79 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 80 – 87 | CytoplasmicSequence analysis | 8 | |
Transmembranei | 88 – 108 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 109 – 112 | ExtracellularSequence analysis | 4 | |
Transmembranei | 113 – 133 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 134 – 144 | CytoplasmicSequence analysisAdd BLAST | 11 | |
Transmembranei | 145 – 165 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 166 – 179 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 180 – 200 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 201 – 266 | CytoplasmicSequence analysisAdd BLAST | 66 | |
Transmembranei | 267 – 285 | Helical; Name=7Sequence analysisAdd BLAST | 19 | |
Topological domaini | 286 – 301 | ExtracellularSequence analysisAdd BLAST | 16 | |
Transmembranei | 302 – 322 | Helical; Name=8Sequence analysisAdd BLAST | 21 | |
Topological domaini | 323 – 328 | CytoplasmicSequence analysis | 6 | |
Transmembranei | 329 – 349 | Helical; Name=9Sequence analysisAdd BLAST | 21 | |
Topological domaini | 350 – 363 | ExtracellularSequence analysisAdd BLAST | 14 | |
Transmembranei | 364 – 384 | Helical; Name=10Sequence analysisAdd BLAST | 21 | |
Topological domaini | 385 – 404 | CytoplasmicSequence analysisAdd BLAST | 20 | |
Transmembranei | 405 – 425 | Helical; Name=11Sequence analysisAdd BLAST | 21 | |
Topological domaini | 426 – 432 | ExtracellularSequence analysis | 7 | |
Transmembranei | 433 – 453 | Helical; Name=12Sequence analysisAdd BLAST | 21 | |
Topological domaini | 454 – 557 | CytoplasmicSequence analysisAdd BLAST | 104 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000050412 | 1 – 557 | High-affinity hexose transporter ght4Add BLAST | 557 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 357 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | O59932 |
PTM databases
iPTMneti | O59932 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 276263, 7 interactors |
STRINGi | 4896.SPBC1683.08.1 |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 492 – 557 | DisorderedSequence analysisAdd BLAST | 66 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 492 – 518 | Basic and acidic residuesSequence analysisAdd BLAST | 27 | |
Compositional biasi | 520 – 557 | Polar residuesSequence analysisAdd BLAST | 38 |
Sequence similaritiesi
Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | O59932 |
OMAi | MACMVIY |
PhylomeDBi | O59932 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
i Sequence
Sequence statusi: Complete.
O59932-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGRTLTSVLV VFISMAGWLG GADTGSISGI LGMRDFQSRF ADRYNPITNS
60 70 80 90 100
YSYSAWRQAL LTGTVNAGCL FGAMLSSPFT EAIGKKYSIA FFSGCYIIGQ
110 120 130 140 150
ILLVTAVPSW VQIMVGKLFT GLTIGALSVL SPGYQSEVAP PQIRGAVVST
160 170 180 190 200
YQLFQTCGTL IAACINMGTH KLRKTASWRT SFGINILWGI FLMVGVLFLP
210 220 230 240 250
ESPRYLIYKG RDEEALRIMC QTAELDPESE IIQTNFNTIK SDIEMEMAGG
260 270 280 290 300
KARWPEVFGK EVRYRTVLGF LTMLLRELIG NNYYFYYATQ VFKGTGMTDI
310 320 330 340 350
FLPAVILGAI NFGTTFGALY TIDNLGRRNP LIFGAAFQSI CFFIYAAVGD
360 370 380 390 400
RKLIYKNGTS DHRAGAVMIV FSCLFLFSYC CSWGPMGWVI VGETFPIRYR
410 420 430 440 450
SKCAAVATSG NWLGNFMVSF FTPFISNSIG FKLGYIYACI NMTSAFQIFL
460 470 480 490 500
MAKETKGLTL EEVNELYESD IKPWDSYKYV RQIESRRIHF SKEEEKRERE
510 520 530 540 550
KSKGYRGQEE RFIENADGAD NDDSSASSES FASAGAHSRS VFPRRSNVSE
ESHPTWV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF051140 Genomic DNA Translation: AAC63976.1 CU329671 Genomic DNA Translation: CAB91170.1 |
PIRi | T43657 |
RefSeqi | NP_595064.1, NM_001020970.2 |
Genome annotation databases
EnsemblFungii | SPBC1683.08.1; SPBC1683.08.1:pep; SPBC1683.08 |
GeneIDi | 2539710 |
KEGGi | spo:SPBC1683.08 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF051140 Genomic DNA Translation: AAC63976.1 CU329671 Genomic DNA Translation: CAB91170.1 |
PIRi | T43657 |
RefSeqi | NP_595064.1, NM_001020970.2 |
3D structure databases
AlphaFoldDBi | O59932 |
SMRi | O59932 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 276263, 7 interactors |
STRINGi | 4896.SPBC1683.08.1 |
PTM databases
iPTMneti | O59932 |
Proteomic databases
PaxDbi | O59932 |
Genome annotation databases
EnsemblFungii | SPBC1683.08.1; SPBC1683.08.1:pep; SPBC1683.08 |
GeneIDi | 2539710 |
KEGGi | spo:SPBC1683.08 |
Organism-specific databases
PomBasei | SPBC1683.08, ght4 |
VEuPathDBi | FungiDB:SPBC1683.08 |
Phylogenomic databases
eggNOGi | KOG0254, Eukaryota |
HOGENOMi | CLU_001265_30_1_1 |
InParanoidi | O59932 |
OMAi | MACMVIY |
PhylomeDBi | O59932 |
Miscellaneous databases
PROi | PR:O59932 |
Family and domain databases
Gene3Di | 1.20.1250.20, 1 hit |
InterProi | View protein in InterPro IPR020846, MFS_dom IPR005828, MFS_sugar_transport-like IPR036259, MFS_trans_sf IPR003663, Sugar/inositol_transpt IPR005829, Sugar_transporter_CS |
Pfami | View protein in Pfam PF00083, Sugar_tr, 1 hit |
PRINTSi | PR00171, SUGRTRNSPORT |
SUPFAMi | SSF103473, SSF103473, 1 hit |
TIGRFAMsi | TIGR00879, SP, 1 hit |
PROSITEi | View protein in PROSITE PS50850, MFS, 1 hit PS00216, SUGAR_TRANSPORT_1, 1 hit PS00217, SUGAR_TRANSPORT_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | GHT4_SCHPO | |
Accessioni | O59932Primary (citable) accession number: O59932 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 11, 2001 |
Last sequence update: | November 1, 1998 | |
Last modified: | May 25, 2022 | |
This is version 143 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Fungal Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- Schizosaccharomyces pombe
Schizosaccharomyces pombe: entries and gene names - SIMILARITY comments
Index of protein domains and families