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Protein

Putative ATP-dependent RNA helicase C550.03c

Gene

SPCC550.03c

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

RNA helicase component of the SKI complex involved in 3'-mRNA degradation pathway.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi302 – 309ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHelicase, Hydrolase, RNA-binding
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-SPO-429958 mRNA decay by 3' to 5' exoribonuclease

Names & Taxonomyi

Protein namesi
Recommended name:
Putative ATP-dependent RNA helicase C550.03c (EC:3.6.4.-)
Gene namesi
ORF Names:SPCC550.03c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome III

Organism-specific databases

EuPathDBiFungiDB:SPCC550.03c
PomBaseiSPCC550.03c

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003107851 – 1213Putative ATP-dependent RNA helicase C550.03cAdd BLAST1213

Proteomic databases

MaxQBiO59801
PaxDbiO59801
PRIDEiO59801

PTM databases

iPTMnetiO59801

Interactioni

Subunit structurei

Component of the SKI complex.By similarity

Protein-protein interaction databases

BioGridi275422, 62 interactors
STRINGi4896.SPCC550.03c.1

Structurei

3D structure databases

ProteinModelPortaliO59801
SMRiO59801
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini289 – 445Helicase ATP-bindingPROSITE-ProRule annotationAdd BLAST157
Domaini545 – 736Helicase C-terminalPROSITE-ProRule annotationAdd BLAST192

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi393 – 396DEAH box4

Sequence similaritiesi

Belongs to the helicase family. SKI2 subfamily.Curated

Phylogenomic databases

HOGENOMiHOG000163048
InParanoidiO59801
KOiK12599
OMAiTQYPFWP
OrthoDBiEOG092C0MRM
PhylomeDBiO59801

Family and domain databases

CDDicd00079 HELICc, 1 hit
InterProiView protein in InterPro
IPR011545 DEAD/DEAH_box_helicase_dom
IPR014001 Helicase_ATP-bd
IPR001650 Helicase_C
IPR027417 P-loop_NTPase
IPR025696 rRNA_proc-arch_dom
IPR016438 Ski2-like
IPR012961 Ski2_C
PfamiView protein in Pfam
PF00270 DEAD, 1 hit
PF08148 DSHCT, 1 hit
PF00271 Helicase_C, 1 hit
PF13234 rRNA_proc-arch, 1 hit
PIRSFiPIRSF005198 Antiviral_helicase_SKI2, 1 hit
SMARTiView protein in SMART
SM00487 DEXDc, 1 hit
SM01142 DSHCT, 1 hit
SM00490 HELICc, 1 hit
SUPFAMiSSF52540 SSF52540, 3 hits
PROSITEiView protein in PROSITE
PS51192 HELICASE_ATP_BIND_1, 1 hit
PS51194 HELICASE_CTER, 1 hit

Sequencei

Sequence statusi: Complete.

O59801-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSKLVDAIN EVAVSNKDKI ELDGIKDDSF DGHLSITEAT YDVDTFLKPS
60 70 80 90 100
PALSKDWIRK LQKKWDREIT YKGLYEYPET LARTQIRFQR HGLEGKIMGY
110 120 130 140 150
KEVPELIEDL NSKNSSSFLR KPSSKNEFVR GSTSNIPFLA DDSDVDAIAG
160 170 180 190 200
EPSVKMALYG EDGLLQVPPG FSRGLSMTAT STTDNLNDEF DPEKWDTKKV
210 220 230 240 250
KSSNRNFVTI HELNEHLKNV NSKHSEIDDL LPDKRSIVSL PPSTLNLHKQ
260 270 280 290 300
PDYAHVVDSS APIENFQQLV PEMALDFPFE LDNFQKEAIY HLEMGDSVFV
310 320 330 340 350
AAHTSAGKTV VAEYAIALAQ KHMTKAIYTS PIKALSNQKF RDFKHKFEDV
360 370 380 390 400
GILTGDVQVN PEGSCLLMTT EILRSMLYRG ADLIRDVEFV IFDEVHYVND
410 420 430 440 450
LERGVVWEEV IIMLPPHVTL ILLSATVPNT KEFASWVGRT KKKNIYVIST
460 470 480 490 500
LKRPVPLEHY LWVKQNMFKI VDQHGRFLMD GYKSANDALK KPDKPVIAKD
510 520 530 540 550
NKNSARGRGA ARGRGVQTNM MRGRGSAKSV ERRDANTWVH LIGHLHKQNL
560 570 580 590 600
LPVIVFVFSK KRCEEYVDTL TNRDLNNHQE KSEVHVVIEK AVARLKKEDR
610 620 630 640 650
LLPQIGRMRE MLSRGLAVHH GGLLPIIKEI VEILFQRGLV KVLFATETFA
660 670 680 690 700
MGVNMPAKSV VFSGTQKHDG RNFRDLLPGE YTQCSGRAGR RGLDVTGTVI
710 720 730 740 750
ILSRSELPDT ASLRHMIMGP SSKLISQFRL TYNMILNLLR VETLRIEDMI
760 770 780 790 800
KRSFSENVNQ TLVPQHEEKI KSFEEKLSAL KKEMSDVDLK EIKSCLLSSE
810 820 830 840 850
SFKEYTKKMH FRAITTANGK RIFKDGRVIV FQQLDFTRTV GVLLGTSIRT
860 870 880 890 900
NASDCTLEVA YLNPQNNLKR PSDLLAFADA FNDVYDNAIF DESNQFKYGL
910 920 930 940 950
INLSGIERVC NTILRIDSGG IRDRRGGAFR KLSEQFASIK KFSDLLFEEV
960 970 980 990 1000
NWSKVRDFEF CEAFEKRNFL QNKLSGNPII STPNFLTHFA LAYQEYELES
1010 1020 1030 1040 1050
NIDNLSSYIS DQNLELLPDY EQRIKVLQEL GYIDAERTVL LKGRVACEIN
1060 1070 1080 1090 1100
STSELVLTEL ILENSLADFS CEETIALLSA FVFDEKTEVE PTISPHLQKG
1110 1120 1130 1140 1150
KEMILSVAEK VNQIQEHYQV LYFNEGNDFE SQPRFGLMEV CYEWARGMSF
1160 1170 1180 1190 1200
NRITDLTDVL EGSIVRTIIR LDEVLRECRG AARVVGDSSM YTKMEECQNL
1210
IRRNIVFCPS LYM
Length:1,213
Mass (Da):138,028
Last modified:August 1, 1998 - v1
Checksum:i2F9BE2ABF8068A37
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329672 Genomic DNA Translation: CAA19107.1
PIRiT41378
RefSeqiNP_588095.1, NM_001023086.2

Genome annotation databases

EnsemblFungiiSPCC550.03c.1; SPCC550.03c.1:pep; SPCC550.03c
GeneIDi2538841
KEGGispo:SPCC550.03c

Similar proteinsi

Entry informationi

Entry nameiSKI2_SCHPO
AccessioniPrimary (citable) accession number: O59801
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 13, 2007
Last sequence update: August 1, 1998
Last modified: June 20, 2018
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

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