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Protein

Thermosome subunit

Gene

ths

Organism
Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Molecular chaperone; binds unfolded polypeptides in vitro, and has a weak ATPase activity.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionChaperone
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPHOR70601:G1G39-20-MONOMER
BRENDAi3.6.4.B10 5244

Names & Taxonomyi

Protein namesi
Recommended name:
Thermosome subunit
Alternative name(s):
Chaperonin subunit
Gene namesi
Name:ths
Ordered Locus Names:PH0017
OrganismiPyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
Taxonomic identifieri70601 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaThermococciThermococcalesThermococcaceaePyrococcus
Proteomesi
  • UP000000752 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001283961 – 549Thermosome subunitAdd BLAST549

Proteomic databases

PRIDEiO57762

Interactioni

Subunit structurei

Forms an oligomeric complex of eight-membered rings.By similarity

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-29172N
IntActiO57762, 2 interactors
MINTiO57762
STRINGi70601.PH0017

Structurei

3D structure databases

ProteinModelPortaliO57762
SMRiO57762
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the TCP-1 chaperonin family.Curated

Phylogenomic databases

eggNOGiarCOG01257 Archaea
COG0459 LUCA
HOGENOMiHOG000226730
KOiK22447
OMAiQFCLSPP
OrthoDBiPOG093Z02BT

Family and domain databases

CDDicd03343 cpn60, 1 hit
Gene3Di1.10.560.10, 2 hits
3.30.260.10, 2 hits
3.50.7.10, 1 hit
InterProiView protein in InterPro
IPR017998 Chaperone_TCP-1
IPR002194 Chaperonin_TCP-1_CS
IPR002423 Cpn60/TCP-1
IPR027409 GroEL-like_apical_dom_sf
IPR027413 GROEL-like_equatorial_sf
IPR027410 TCP-1-like_intermed_sf
IPR012714 Thermosome_arc
PfamiView protein in Pfam
PF00118 Cpn60_TCP1, 1 hit
PRINTSiPR00304 TCOMPLEXTCP1
SUPFAMiSSF48592 SSF48592, 2 hits
SSF52029 SSF52029, 1 hit
SSF54849 SSF54849, 2 hits
TIGRFAMsiTIGR02339 thermosome_arch, 1 hit
PROSITEiView protein in PROSITE
PS00750 TCP1_1, 1 hit
PS00751 TCP1_2, 1 hit
PS00995 TCP1_3, 1 hit

Sequencei

Sequence statusi: Complete.

O57762-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQLAGQPIL ILPEGTQRYV GRDAQRMNIL AARIIAETVR TTLGPKGMDK
60 70 80 90 100
MLVDSLGDIV ITNDGATILD EMDIQHPAAK MMVEVAKTQD KEAGDGTTTA
110 120 130 140 150
VVIAGELLKK AEELLDQNIH PSIIIKGYTL ASQKAQEILD SIAKEVKPDD
160 170 180 190 200
EEVLLKAAMT AITGKAAEEE REYLAKLAVE AVKLVAEEKD GKLKVDIDNI
210 220 230 240 250
KLEKKEGGAV RDTRLIRGVV IDKEVVHPGM PKRIENAKIA LINDALEVKE
260 270 280 290 300
TETDAEIRIT SPEQLQAFLE QEEKMLKEMV DKIKEVGANV VFVQKGIDDL
310 320 330 340 350
AQHYLAKYGI LAVRRVKKSD MEKLAKATGA KIVTNIRDLT PEDLGEAELV
360 370 380 390 400
EERKVAGENM IFVEGCKNPK AVTILIRGGT EHVVDEVERA LEDAIKVVKD
410 420 430 440 450
ILEDGKIIAG GGASEIELSI KLDEYAKEVG GKEQLAIEAF AEALKVIPRT
460 470 480 490 500
LAENAGLDPI ETLVKVIAAH KEKGQTIGID VYEGEPADMM ERGVIEPVRV
510 520 530 540
KKQAIKSASE AAIMILRIDD VIAASKLEKE KEGEKGGGSE EFSGSSDLD
Length:549
Mass (Da):59,693
Last modified:August 1, 1998 - v1
Checksum:i9A451CA8C6CFEB4D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000001 Genomic DNA Translation: BAA29085.1
PIRiF71219
RefSeqiWP_010884137.1, NC_000961.1

Genome annotation databases

EnsemblBacteriaiBAA29085; BAA29085; BAA29085
GeneIDi1443919
KEGGipho:PH0017

Similar proteinsi

Entry informationi

Entry nameiTHS_PYRHO
AccessioniPrimary (citable) accession number: O57762
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 30, 2000
Last sequence update: August 1, 1998
Last modified: June 20, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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