UniProtKB - O57662 (O57662_XENLA)
Protein
Submitted name:
Potassium channel xKv4.3
Gene
kcnd3.L
Organism
Xenopus laevis (African clawed frog)
Status
Functioni
GO - Molecular functioni
- voltage-gated potassium channel activity Source: InterPro
GO - Biological processi
- protein homooligomerization Source: InterPro
- regulation of ion transmembrane transport Source: UniProtKB-KW
Keywordsi
Molecular function | Ion channel, Potassium channelARBA annotation, Voltage-gated channelARBA annotation |
Biological process | Ion transport, Potassium transport, Transport |
Ligand | Potassium |
Names & Taxonomyi
Protein namesi | Submitted name: Potassium channel xKv4.3Imported |
Gene namesi | |
Organismi | Xenopus laevis (African clawed frog)Imported |
Taxonomic identifieri | 8355 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus |
Organism-specific databases
Xenbasei | XB-GENE-5867986, kcnd3.L |
Subcellular locationi
Other locations
- dendrite ARBA annotation
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- voltage-gated potassium channel complex Source: InterPro
Other locations
- dendrite Source: UniProtKB-SubCell
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 181 – 202 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 222 – 246 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 258 – 275 | HelicalSequence analysisAdd BLAST | 18 | |
Transmembranei | 325 – 346 | HelicalSequence analysisAdd BLAST | 22 | |
Transmembranei | 358 – 374 | HelicalSequence analysisAdd BLAST | 17 |
Keywords - Cellular componenti
Cell projectionARBA annotation, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 16 | Sequence analysisAdd BLAST | 16 | |
ChainiPRO_5004159036 | 17 – 659 | Sequence analysisAdd BLAST | 643 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 38 – 107 | BTBInterPro annotationAdd BLAST | 70 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 623 – 651 | DisorderedSequence analysisAdd BLAST | 29 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 137 – 157 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysis, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
OrthoDBi | 469107at2759 |
Family and domain databases
Gene3Di | 1.20.120.350, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR005821, Ion_trans_dom IPR003968, K_chnl_volt-dep_Kv IPR003975, K_chnl_volt-dep_Kv4 IPR004056, K_chnl_volt-dep_Kv4.3 IPR024587, K_chnl_volt-dep_Kv4_C IPR021645, Shal-type_N IPR011333, SKP1/BTB/POZ_sf IPR003131, T1-type_BTB IPR028325, VG_K_chnl IPR027359, Volt_channel_dom_sf |
PANTHERi | PTHR11537, PTHR11537, 1 hit |
Pfami | View protein in Pfam PF02214, BTB_2, 1 hit PF11879, DUF3399, 1 hit PF00520, Ion_trans, 1 hit PF11601, Shal-type, 1 hit |
PRINTSi | PR01518, KV43CHANNEL PR01491, KVCHANNEL PR01497, SHALCHANNEL |
SMARTi | View protein in SMART SM00225, BTB, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit |
i Sequence
Sequence statusi: Complete.
O57662-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MASGVAAWLP FARAAAIGWM PVANCPMPLA PADKNKKQDE VIILNVSGRR
60 70 80 90 100
FQTWRTTLER YPDNLLGRPE KEFFFNEETK EYFFDRDPEV FRSILNFYRT
110 120 130 140 150
GKLHYPRYEY ISAYDEELSF YGILPEIIGD CCYEEYKDRK RENAERLMDD
160 170 180 190 200
NEFENKQEAM PSLNLRETMW RAFENPHTST LALVFYYVTG FFIAVSVIAN
210 220 230 240 250
VVETVPCGTV PGNKELPCGE RYQVAFFCLD TACVMIFTVE YLLRLFAAPS
260 270 280 290 300
RYRFMRSVMR SVMSIDVVAI MPYYIGLVMT NINEDVSGAF VTLRVFRVFR
310 320 330 340 350
IFKFSRHSQG LRILGYTLKS CASELGFLLF SLTMAIIIFA TVMFYAEKGS
360 370 380 390 400
TSSKFTSIPA SFWYTIVTMT TLGYGDMVPK TIAGKIFEFH LTSLSGVLVI
410 420 430 440 450
ALPDPVMVSN FSRIYHQNQR ADKRRAQKKA RLARIRVAKT GSSTAYLHSK
460 470 480 490 500
RNGLLNEALE LMGSTEEPHI GKSASLIESQ HHHLLHCLEK TTGLSYLVDD
510 520 530 540 550
PLLSVRTSDH EEPCSLWMSQ MFEQNCRENS CKNYPSTATA SLSSHHGLTT
560 570 580 590 600
SCCSRRNKKT THLPNSNVPA TRLRTMQELS TIHIQCSDQP SLTASRSSLN
610 620 630 640 650
LKSEDEMRSN CKASQITTAI ISIPTPPALT PEGETRPGSP PGRSTNIHST
SNIVKVSAL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U89265 mRNA Translation: AAB94379.1 |
RefSeqi | NP_001079287.1, NM_001085818.1 |
Genome annotation databases
GeneIDi | 378574 |
KEGGi | xla:378574 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | U89265 mRNA Translation: AAB94379.1 |
RefSeqi | NP_001079287.1, NM_001085818.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Genome annotation databases
GeneIDi | 378574 |
KEGGi | xla:378574 |
Organism-specific databases
CTDi | 378574 |
Xenbasei | XB-GENE-5867986, kcnd3.L |
Phylogenomic databases
OrthoDBi | 469107at2759 |
Family and domain databases
Gene3Di | 1.20.120.350, 1 hit |
InterProi | View protein in InterPro IPR000210, BTB/POZ_dom IPR005821, Ion_trans_dom IPR003968, K_chnl_volt-dep_Kv IPR003975, K_chnl_volt-dep_Kv4 IPR004056, K_chnl_volt-dep_Kv4.3 IPR024587, K_chnl_volt-dep_Kv4_C IPR021645, Shal-type_N IPR011333, SKP1/BTB/POZ_sf IPR003131, T1-type_BTB IPR028325, VG_K_chnl IPR027359, Volt_channel_dom_sf |
PANTHERi | PTHR11537, PTHR11537, 1 hit |
Pfami | View protein in Pfam PF02214, BTB_2, 1 hit PF11879, DUF3399, 1 hit PF00520, Ion_trans, 1 hit PF11601, Shal-type, 1 hit |
PRINTSi | PR01518, KV43CHANNEL PR01491, KVCHANNEL PR01497, SHALCHANNEL |
SMARTi | View protein in SMART SM00225, BTB, 1 hit |
SUPFAMi | SSF54695, SSF54695, 1 hit |
PROSITEi | View protein in PROSITE PS50097, BTB, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | O57662_XENLA | |
Accessioni | O57662Primary (citable) accession number: O57662 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 1998 |
Last sequence update: | June 1, 1998 | |
Last modified: | December 2, 2020 | |
This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |