UniProtKB - O57457 (E41LA_DANRE)
Protein
Band 4.1-like protein 4
Gene
epb41l4a
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
Not known, binds calmodulin.
GO - Molecular functioni
- calmodulin binding Source: UniProtKB-KW
GO - Biological processi
- actomyosin structure organization Source: GO_Central
Keywordsi
Molecular function | Calmodulin-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Band 4.1-like protein 4Alternative name(s): Erythrocyte membrane protein band 4.1-like 4ABy similarity Protein Nbl4 |
Gene namesi | |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio) |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-990415-20, epb41l4a |
Subcellular locationi
Cytoskeleton
- cytoskeleton By similarity
Cytoskeleton
- cytoskeleton Source: GO_Central
Other locations
- cytoplasm Source: UniProtKB-KW
Keywords - Cellular componenti
Cytoplasm, CytoskeletonPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000219403 | 1 – 619 | Band 4.1-like protein 4Add BLAST | 619 |
Proteomic databases
PaxDbi | O57457 |
PRIDEi | O57457 |
Expressioni
Tissue specificityi
In adults, it is found in the ovary, eye, heart and brain, but not in gut or skeletal muscle.
Interactioni
GO - Molecular functioni
- calmodulin binding Source: UniProtKB-KW
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000058626 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 11 – 299 | FERMPROSITE-ProRule annotationAdd BLAST | 289 |
Phylogenomic databases
eggNOGi | KOG3530, Eukaryota |
InParanoidi | O57457 |
PhylomeDBi | O57457 |
Family and domain databases
CDDi | cd14473, FERM_B-lobe, 1 hit |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR030696, Band4.1-like4A IPR019749, Band_41_domain IPR014847, FERM-adjacent IPR014352, FERM/acyl-CoA-bd_prot_sf IPR035963, FERM_2 IPR019748, FERM_central IPR019747, FERM_CS IPR000299, FERM_domain IPR018979, FERM_N IPR018980, FERM_PH-like_C IPR011993, PH-like_dom_sf IPR029071, Ubiquitin-like_domsf |
PANTHERi | PTHR23280:SF4, PTHR23280:SF4, 1 hit |
Pfami | View protein in Pfam PF08736, FA, 1 hit PF09380, FERM_C, 1 hit PF00373, FERM_M, 1 hit PF09379, FERM_N, 1 hit |
PRINTSi | PR00935, BAND41 |
SMARTi | View protein in SMART SM00295, B41, 1 hit SM01195, FA, 1 hit SM01196, FERM_C, 1 hit |
SUPFAMi | SSF47031, SSF47031, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS00660, FERM_1, 1 hit PS00661, FERM_2, 1 hit PS50057, FERM_3, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
O57457-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSCFCSVQEE FYCEVLLLDE SKLILTTQQQ GIKKSTRGSV VLDYVFSHVN
60 70 80 90 100
LAETEYFGVR YCDRSHQTFW LDPSKTLAEH KDLIATGPPY TLYFGVKFYA
110 120 130 140 150
EDPGKLKEEI TRYQFFLQVK QDVLQGRLPC AFNISAQLAA LAIQSELGDY
160 170 180 190 200
DPYKHTAGYV SEYRFVPDQK EDLEDSIEQI HKTLLGQVPA EAENNYLAIA
210 220 230 240 250
KTLEMYGVDL HPVFGEKQAE YFLGLTPVGV VVYKNKTQVG KYFWPRITKV
260 270 280 290 300
YFKETQFELR VLGRDCNETS FFFDAASKTA CKNLWKCCVE HHTFFRMPEN
310 320 330 340 350
ESNSLTRKLS KFSSLGSKHR YSGKTAMQIG RESTETLPRA DLQVIRTRSK
360 370 380 390 400
TYPKRSTQPA GRNNGGQAVT KMENTSEGQP KTSALTPVKS PRVKAESASV
410 420 430 440 450
QQEKPSAPWE EDAPQSGLYN SASERNKSPK FPKAHRRSPS GGSENEPRHR
460 470 480 490 500
RGQTADDAQA NKQHRRRSRS RGNTSSGSES ENSNREHRKK RNRSRQSNEM
510 520 530 540 550
VDSAPQWEVV LRRQKEKTPN DPNQRRSRHR SRSRSPDVQA KEQLWKHIQK
560 570 580 590 600
ELVDPSGLSE EQLKEIPYKK VETQGDPIKI RHSHSPRSFG STGAPTARTE
610
RGLCCPKSTL ALIWFLLWL
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketE7F2L0 | E7F2L0_DANRE | Band 4.1-like protein 4 | epb41l4a epb4.1l4 | 671 | Annotation score: | ||
F1QZK3 | F1QZK3_DANRE | Band 4.1-like protein 4 | epb41l4a epb4.1l4 | 603 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF025306 mRNA Translation: AAB97965.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AF025306 mRNA Translation: AAB97965.1 |
3D structure databases
SMRi | O57457 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000058626 |
Proteomic databases
PaxDbi | O57457 |
PRIDEi | O57457 |
Organism-specific databases
ZFINi | ZDB-GENE-990415-20, epb41l4a |
Phylogenomic databases
eggNOGi | KOG3530, Eukaryota |
InParanoidi | O57457 |
PhylomeDBi | O57457 |
Miscellaneous databases
PROi | PR:O57457 |
Family and domain databases
CDDi | cd14473, FERM_B-lobe, 1 hit |
Gene3Di | 1.20.80.10, 1 hit 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR030696, Band4.1-like4A IPR019749, Band_41_domain IPR014847, FERM-adjacent IPR014352, FERM/acyl-CoA-bd_prot_sf IPR035963, FERM_2 IPR019748, FERM_central IPR019747, FERM_CS IPR000299, FERM_domain IPR018979, FERM_N IPR018980, FERM_PH-like_C IPR011993, PH-like_dom_sf IPR029071, Ubiquitin-like_domsf |
PANTHERi | PTHR23280:SF4, PTHR23280:SF4, 1 hit |
Pfami | View protein in Pfam PF08736, FA, 1 hit PF09380, FERM_C, 1 hit PF00373, FERM_M, 1 hit PF09379, FERM_N, 1 hit |
PRINTSi | PR00935, BAND41 |
SMARTi | View protein in SMART SM00295, B41, 1 hit SM01195, FA, 1 hit SM01196, FERM_C, 1 hit |
SUPFAMi | SSF47031, SSF47031, 1 hit SSF54236, SSF54236, 1 hit |
PROSITEi | View protein in PROSITE PS00660, FERM_1, 1 hit PS00661, FERM_2, 1 hit PS50057, FERM_3, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | E41LA_DANRE | |
Accessioni | O57457Primary (citable) accession number: O57457 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 15, 1999 |
Last sequence update: | June 1, 1998 | |
Last modified: | October 7, 2020 | |
This is version 117 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |