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Protein

Proteasome subunit beta type

Gene

psmb6

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

Cleavage of peptide bonds with very broad specificity.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase, Protease, Threonine proteaseUniRule annotation

Protein family/group databases

MEROPSiT01.010

Names & Taxonomyi

Protein namesi
Recommended name:
Proteasome subunit beta typeUniRule annotation (EC:3.4.25.1UniRule annotation)
Gene namesi
Name:psmb6Imported
Synonyms:YImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990415-216 psmb6

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

CytoplasmUniRule annotation, NucleusUniRule annotationSAAS annotation, ProteasomeUniRule annotationImported

Interactioni

Subunit structurei

The 26S proteasome consists of a 20S proteasome core and two 19S regulatory subunits.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliO57332
SMRiO57332
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the peptidase T1B family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0174 Eukaryota
ENOG410XS23 LUCA
HOGENOMiHOG000091079
HOVERGENiHBG000123
KOiK02738

Family and domain databases

Gene3Di3.60.20.10, 1 hit
InterProiView protein in InterPro
IPR029055 Ntn_hydrolases_N
IPR000243 Pept_T1A_subB
IPR035140 Proteasome_beta6
IPR016050 Proteasome_bsu_CS
IPR001353 Proteasome_sua/b
IPR023333 Proteasome_suB-type
PANTHERiPTHR11599:SF46 PTHR11599:SF46, 1 hit
PfamiView protein in Pfam
PF00227 Proteasome, 1 hit
PRINTSiPR00141 PROTEASOME
SUPFAMiSSF56235 SSF56235, 1 hit
PROSITEiView protein in PROSITE
PS00854 PROTEASOME_BETA_1, 1 hit
PS51476 PROTEASOME_BETA_2, 1 hit

Sequencei

Sequence statusi: Complete.

O57332-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASTLNNYND LCPDWTQREV STGTTIMAVE FDGGVVMGAD SRTTTGAYIA
60 70 80 90 100
NRVTDKLTPI HDRIFCCRSG SAADTQAIAD AVTYQLGFHS IELDEAPLVQ
110 120 130 140 150
TAASLFRDMC YRYREELMAG IIVAGWDRRR GGQVYTVPVG GMLTRQPVSV
160 170 180 190 200
GGSGSSYIYG YVDSNYRSGM SKEECLKFTA GALTLPMERD GSSGGVVRLA
210 220
VISEQGVERQ AILGNQLPQF STV
Length:223
Mass (Da):24,123
Last modified:June 1, 1998 - v1
Checksum:i1B7258CAD584B897
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF032392 mRNA Translation: AAB87681.1
RefSeqiNP_571227.1, NM_131152.1
UniGeneiDr.11843

Genome annotation databases

GeneIDi30388
KEGGidre:30388

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF032392 mRNA Translation: AAB87681.1
RefSeqiNP_571227.1, NM_131152.1
UniGeneiDr.11843

3D structure databases

ProteinModelPortaliO57332
SMRiO57332
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiT01.010

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi30388
KEGGidre:30388

Organism-specific databases

CTDi5694
ZFINiZDB-GENE-990415-216 psmb6

Phylogenomic databases

eggNOGiKOG0174 Eukaryota
ENOG410XS23 LUCA
HOGENOMiHOG000091079
HOVERGENiHBG000123
KOiK02738

Family and domain databases

Gene3Di3.60.20.10, 1 hit
InterProiView protein in InterPro
IPR029055 Ntn_hydrolases_N
IPR000243 Pept_T1A_subB
IPR035140 Proteasome_beta6
IPR016050 Proteasome_bsu_CS
IPR001353 Proteasome_sua/b
IPR023333 Proteasome_suB-type
PANTHERiPTHR11599:SF46 PTHR11599:SF46, 1 hit
PfamiView protein in Pfam
PF00227 Proteasome, 1 hit
PRINTSiPR00141 PROTEASOME
SUPFAMiSSF56235 SSF56235, 1 hit
PROSITEiView protein in PROSITE
PS00854 PROTEASOME_BETA_1, 1 hit
PS51476 PROTEASOME_BETA_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiO57332_DANRE
AccessioniPrimary (citable) accession number: O57332
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: May 23, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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