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Protein

Virion infectivity factor

Gene

vif

Organism
Human immunodeficiency virus 1
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processHost-virus interactionSAAS annotation, Ubl conjugation pathwaySAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Virion infectivity factorUniRule annotation
Gene namesi
Name:vifImported
OrganismiHuman immunodeficiency virus 1Imported
Taxonomic identifieri11676 [NCBI]
Taxonomic lineageiVirusesOrterviralesRetroviridaeOrthoretrovirinaeLentivirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]

Subcellular locationi

  • Host cell membrane UniRule annotationSAAS annotation; Peripheral membrane protein UniRule annotationSAAS annotation; Cytoplasmic side UniRule annotationSAAS annotation
  • Host cytoplasm UniRule annotation
  • Virion UniRule annotationSAAS annotation
  • Note: In the cytoplasm, seems to colocalize with intermediate filament vimentin. A fraction is associated with the cytoplasmic side of cellular membranes, presumably via the interaction with Pr55Gag precursor.UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host cell membraneSAAS annotation, Host cytoplasmSAAS annotation, Host membrane, Membrane, VirionSAAS annotation

Family & Domainsi

Sequence similaritiesi

Belongs to the primate lentivirus group Vif protein family.UniRule annotationSAAS annotation

Family and domain databases

HAMAPiMF_04081 HIV_VIF, 1 hit
InterProiView protein in InterPro
IPR000475 Viral_infect
PfamiView protein in Pfam
PF00559 Vif, 1 hit
PRINTSiPR00349 VIRIONINFFCT

Sequencei

Sequence statusi: Complete.

O55973-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MENRWQVMIV WQVDRMRIKT WKSLVKHHMY RSGRARESFY RHHYESTHPK
60 70 80 90 100
ISSEVHIPLG DARLVVTTYW GMHTGERDWH LGQGVSIEWR KRRYSTQVDP
110 120 130 140 150
NLADQLRHLY YFDCFSESAI RNAILGRIVR PSCDFQAGHN KVGTRQYLAL
160 170 180 190
AALITPKKIK PPLPSVAKLT EDRWNNPQNT KGHRGSHTMN GH
Length:192
Mass (Da):22,567
Last modified:June 1, 1998 - v1
Checksum:i98A5C26FC22F3A3A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF019474 Genomic DNA Translation: AAC02351.1

Similar proteinsi

Entry informationi

Entry nameiO55973_9HIV1
AccessioniPrimary (citable) accession number: O55973
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: July 18, 2018
This is version 85 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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