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Protein

Protein NipSnap homolog 2

Gene

Nipsnap2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May act as a positive regulator of L-type calcium channels.1 Publication

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NipSnap homolog 2
Short name:
NipSnap2
Alternative name(s):
Glioblastoma-amplified sequence
Gene namesi
Name:Nipsnap2
Synonyms:Gbas
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:1278343 Nipsnap2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Membrane, Mitochondrion, Mitochondrion outer membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002211491 – 281Protein NipSnap homolog 2Add BLAST281

Proteomic databases

EPDiO55126
MaxQBiO55126
PaxDbiO55126
PeptideAtlasiO55126
PRIDEiO55126

PTM databases

iPTMnetiO55126
PhosphoSitePlusiO55126
SwissPalmiO55126

Expressioni

Gene expression databases

CleanExiMM_GBAS

Interactioni

Subunit structurei

Interacts with VDAC1.By similarity

Protein-protein interaction databases

IntActiO55126, 4 interactors
MINTiO55126
STRINGi10090.ENSMUSP00000083211

Structurei

3D structure databases

ProteinModelPortaliO55126
SMRiO55126
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NipSnap family.Curated

Phylogenomic databases

eggNOGiKOG2883 Eukaryota
ENOG410XSWP LUCA
HOGENOMiHOG000194298
HOVERGENiHBG052627
InParanoidiO55126
PhylomeDBiO55126

Family and domain databases

InterProiView protein in InterPro
IPR011008 Dimeric_a/b-barrel
IPR012577 NIPSNAP
PfamiView protein in Pfam
PF07978 NIPSNAP, 1 hit
SUPFAMiSSF54909 SSF54909, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

O55126-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAARVLLARG GLLRPAAQSA FLPGLRTVTS SSHRAREDSW LKSLFVRKVD
60 70 80 90 100
PRKDAHSNLL AKKETSSLYK LQFHNVKPEC LDAYNKICQE VLPKIHEGKQ
110 120 130 140 150
YPCTLVGTWN TWYGEQDQAV HLWRYEGGYP ALTEVMNKLK ENQEFVNFRK
160 170 180 190 200
ARSDMLLSRK NQLLLEFSFW NEPVPRPGPN IYELRSYQLR PGTMIEWGNY
210 220 230 240 250
WARAIRFRQD SNEAIGGFFS QIGQLYMVDH LWAYRDLQTR EDIRNAAWHK
260 270 280
HGWEELVYYT VPLIQEMESR IMIPLKTSPL Q
Length:281
Mass (Da):32,933
Last modified:June 1, 1998 - v1
Checksum:i260D52675BF1CA7E
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q7TMG8Q7TMG8_MOUSE
Glioblastoma amplified sequence
Nipsnap2 Gbas
281Annotation score:
A0A0G2JEV1A0A0G2JEV1_MOUSE
Protein NipSnap homolog 2
Nipsnap2 Gbas
111Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001261 mRNA Translation: CAA04635.1
CCDSiCCDS19698.1
UniGeneiMm.12468

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ001261 mRNA Translation: CAA04635.1
CCDSiCCDS19698.1
UniGeneiMm.12468

3D structure databases

ProteinModelPortaliO55126
SMRiO55126
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiO55126, 4 interactors
MINTiO55126
STRINGi10090.ENSMUSP00000083211

PTM databases

iPTMnetiO55126
PhosphoSitePlusiO55126
SwissPalmiO55126

Proteomic databases

EPDiO55126
MaxQBiO55126
PaxDbiO55126
PeptideAtlasiO55126
PRIDEiO55126

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1278343 Nipsnap2

Phylogenomic databases

eggNOGiKOG2883 Eukaryota
ENOG410XSWP LUCA
HOGENOMiHOG000194298
HOVERGENiHBG052627
InParanoidiO55126
PhylomeDBiO55126

Miscellaneous databases

ChiTaRSiGbas mouse
PROiPR:O55126
SOURCEiSearch...

Gene expression databases

CleanExiMM_GBAS

Family and domain databases

InterProiView protein in InterPro
IPR011008 Dimeric_a/b-barrel
IPR012577 NIPSNAP
PfamiView protein in Pfam
PF07978 NIPSNAP, 1 hit
SUPFAMiSSF54909 SSF54909, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiNIPS2_MOUSE
AccessioniPrimary (citable) accession number: O55126
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 26, 2001
Last sequence update: June 1, 1998
Last modified: September 12, 2018
This is version 110 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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Main funding by: National Institutes of Health

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