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Protein
Submitted name:

Paired-like homeodomain containing protein

Gene

Esx1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi118 – 177HomeoboxPROSITE-ProRule annotationAdd BLAST60

GO - Molecular functioni

GO - Biological processi

  • blood vessel development Source: MGI
  • labyrinthine layer blood vessel development Source: MGI
  • labyrinthine layer morphogenesis Source: MGI
  • regulation of transcription by RNA polymerase II Source: MGI

Keywordsi

Molecular functionDNA-bindingPROSITE-ProRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Paired-like homeodomain containing proteinImported
Gene namesi
Name:Esx1Imported
Synonyms:EtxImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1096388 Esx1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliO54817
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini116 – 176HomeoboxInterPro annotationAdd BLAST61

Keywords - Domaini

HomeoboxPROSITE-ProRule annotationSAAS annotationImported

Phylogenomic databases

eggNOGiKOG0490 Eukaryota
ENOG410YIJ3 LUCA
HOVERGENiHBG052987

Family and domain databases

CDDicd00086 homeodomain, 1 hit
InterProiView protein in InterPro
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR000047 HTH_motif
PfamiView protein in Pfam
PF00046 Homeobox, 1 hit
PRINTSiPR00031 HTHREPRESSR
SMARTiView protein in SMART
SM00389 HOX, 1 hit
SUPFAMiSSF46689 SSF46689, 1 hit
PROSITEiView protein in PROSITE
PS00027 HOMEOBOX_1, 1 hit
PS50071 HOMEOBOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

O54817-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MENSLFNSMF LEEANYQEPE GFEPSRGEAA APVAEAPQAW NGNENLGGGF
60 70 80 90 100
LEANAQLGEA DAAPVRQSLM RPLMQPVAQS SPQPLPANPL QAPQQPEEQE
110 120 130 140 150
EEEEEQPGEE QPQQEPKPRR YRICFTPIQL QELEAFFQRV QYPDLFARVE
160 170 180 190 200
LARRLGLPEP RVQVWFQNRR AKWRRLRRAQ AFRNMVPVAM SPPVGVYLDD
210 220 230 240 250
HYGPIPIVEV IWKCYPMVPR PMHPQMMPLP PRPPPGFRMP PPFRPPPLPP
260 270 280 290 300
FPWPPVPPDA HIPNAAREYN PFPFPFPFPF PFPNPFPNPN PNPNPNPNPN
310
PNPNQNFAGP RYRY
Length:314
Mass (Da):35,969
Last modified:June 1, 1998 - v1
Checksum:i72568F81DA4AA246
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF004211 mRNA Translation: AAB94670.1
UniGeneiMm.8017

Similar proteinsi

Entry informationi

Entry nameiO54817_MOUSE
AccessioniPrimary (citable) accession number: O54817
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: March 28, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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