UniProtKB - O54781 (SRPK2_MOUSE)

BLAST

>sp|O54781|SRPK2_MOUSE SRSF protein kinase 2 OS=Mus musculus OX=10090 GN=Srpk2 PE=1 SV=2
MSVNSEKSSSSERPEPQQKAPLVPPPPPPPPPPPLPDPAPPEPEEEILGSDDEEQEDPAD
YCKGGYHPVKIGDLFNGRYHVIRKLGWGHFSTVWLCWDMQGKRFVAMKVVKSAQHYTETA
LDEIKLLKCVRESDPSDPNKDMVVQLIDDFKISGMNGIHVCMVFEVLGHHLLKWIIKSNY
QGLPVRCVKSIIRQVLQGLDYLHSKCKIIHTDIKPENILMCVDDAYVRRMAAEATEWQKA
GAPPPSGSAVSTAPQQKPIGKISKNKKKKLKKKQKRQAELLEKRLQEIEELEREAERKIL
EENITSAEASGEQDGEYQPEVTLKAADLEDTTEEETAKDNGEVEDQEEKEDAEKENAEKD
EDDVEQELANLDPTWVESPKANGHIENGPFSLEQQLEDEEDDEDDCANPEEYNLDEPNAE
SDYTYSSSYEQFNGELPNGQHKTSEFPTPLFSGPLEPVACGSVISEGSPLTEQEESSPSH
DRSRTVSASSTGDLPKTKTRAADLLVNPLDPRNADKIRVKIADLGNACWVHKHFTEDIQT
RQYRSIEVLIGAGYSTPADIWSTACMAFELATGDYLFEPHSGEDYSRDEDHIAHIIELLG
SIPRHFALSGKYSREFFNRRGELRHITKLKPWSLFDVLVEKYGWPHEDAAQFTDFLIPML
EMVPEKRASAGECLRHPWLNS

Align
Format
Add to basket Added to basket
History
Entry version 139 (07 Nov 2018)
Sequence version 2 (05 Jul 2005)
Previous versions | rss
Other tutorials and videos
Help video
Feedback

Protein

SRSF protein kinase 2

Gene

Srpk2

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Serine/arginine-rich protein-specific kinase which specifically phosphorylates its substrates at serine residues located in regions rich in arginine/serine dipeptides, known as RS domains and is involved in the phosphorylation of SR splicing factors and the regulation of splicing. Promotes neuronal apoptosis by up-regulating cyclin-D1 (CCND1) expression. This is done by the phosphorylation of SRSF2, leading to the suppression of p53/TP53 phosphorylation thereby relieving the repressive effect of p53/TP53 on cyclin-D1 (CCND1) expression. Phosphorylates ACIN1, and redistributes it from the nuclear speckles to the nucleoplasm, resulting in cyclin A1 but not cyclin A2 up-regulation. Plays an essential role in spliceosomal B complex formation via the phosphorylation of DDX23/PRP28.2 Publications

Catalytic activityⁱ

ATP + a protein = ADP + a phosphoprotein.1 Publication

Cofactorⁱ

Mg²⁺1 Publication

Activity regulationⁱ

Activated by phosphorylation on Ser-50 and Ser-581.By similarity

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Binding siteⁱ	108	ATPPROSITE-ProRule annotationBy similarity		1
Active siteⁱ	212	Proton acceptorPROSITE-ProRule annotationBy similarity		1

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Nucleotide bindingⁱ	85 – 93	ATPPROSITE-ProRule annotationBy similarity		9

GO - Molecular functionⁱ

14-3-3 protein binding
Source: BHF-UCL
Inferred from direct assayⁱ
- 19592491
ATP binding
Source: UniProtKB
Inferred from direct assayⁱ
- 9446799
magnesium ion binding
Source: UniProtKB
Inferred from direct assayⁱ
- 9446799
protein serine/threonine kinase activity
Source: UniProtKB
Inferred from direct assayⁱ
- 9446799

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

angiogenesis
Source: BHF-UCL
Inferred from direct assayⁱ
- 19906640
cell differentiation Source: UniProtKB-KW
intracellular signal transduction
Source: UniProtKB
Inferred from direct assayⁱ
- 9446799
negative regulation of viral genome replication Source: BHF-UCL
nuclear speck organization
Source: BHF-UCL
Inferred from direct assayⁱ
- 9446799
positive regulation of cell cycle
Source: BHF-UCL
Inferred from direct assayⁱ
- 19592491
positive regulation of cell proliferation
Source: BHF-UCL
Inferred from direct assayⁱ
- 19592491
positive regulation of gene expression
Source: BHF-UCL
Inferred from direct assayⁱ
- 19592491
positive regulation of neuron apoptotic process
Source: BHF-UCL
Inferred from direct assayⁱ
- 19592491
positive regulation of viral genome replication Source: BHF-UCL
protein phosphorylation
Source: UniProtKB
Inferred from direct assayⁱ
- 9446799
regulation of gene expression
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
regulation of mRNA processing
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
RNA splicing
Source: UniProtKB
Inferred from direct assayⁱ
- 9446799
spliceosomal complex assembly
Source: UniProtKB
Inferred from direct assayⁱ
- 9446799

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Kinase, Serine/threonine-protein kinase, Transferase
Biological process	Differentiation, mRNA processing, mRNA splicing
Ligand	ATP-binding, Nucleotide-binding

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: SRSF protein kinase 2 (EC:2.7.11.1) Alternative name(s): SFRS protein kinase 2 Serine/arginine-rich protein-specific kinase 2 Short name: SR-protein-specific kinase 2 Cleaved into the following 2 chains: SRSF protein kinase 2 N-terminal SRSF protein kinase 2 C-terminal
Gene namesⁱ	Name:Srpk2Imported
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Unplaced

Organism-specific databases

MGIⁱ	MGI:1201408 Srpk2

Keywords - Cellular componentⁱ

Cytoplasm, Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Length
ChainⁱPRO_0000086678	1 – 681	SRSF protein kinase 2Add BLAST	681
ChainⁱPRO_0000414753	1 – 137	SRSF protein kinase 2 N-terminalAdd BLAST	137
ChainⁱPRO_0000414754	138 – 681	SRSF protein kinase 2 C-terminalAdd BLAST	544

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	50	PhosphoserineCombined sources	1
Modified residueⁱ	331	PhosphothreonineCombined sources	1
Modified residueⁱ	332	PhosphothreonineCombined sources	1
Modified residueⁱ	378	PhosphoserineCombined sources	1
Modified residueⁱ	468	PhosphoserineCombined sources	1
Modified residueⁱ	471	PhosphothreonineCombined sources	1
Modified residueⁱ	477	PhosphoserineCombined sources	1
Modified residueⁱ	479	PhosphoserineCombined sources	1
Modified residueⁱ	483	PhosphoserineCombined sources	1
Modified residueⁱ	485	Phosphothreonine; by PKB/AKT1By similarity	1
Modified residueⁱ	487	PhosphoserineCombined sources	1
Modified residueⁱ	490	PhosphoserineBy similarity	1
Modified residueⁱ	581	Phosphoserine; by CK2By similarity	1

Post-translational modificationⁱ

Phosphorylation at Thr-485 by PKB/AKT1 enhances its stimulatory activity in triggering cyclin-D1 (CCND1) expression and promoting apoptosis in neurons, which can be blocked by YWHAB. It also enhances its protein kinase activity toward ACIN1 and SRSF2, promotes its nuclear translocation and prevents its proteolytic cleavage (By similarity).By similarity

Proteolytically cleaved at Asp-137 and Asp-401 by caspase-3 during apoptotic cell death. Cleavage at Asp-137 which is the major site of cleavage, produces a small N-terminal fragment that translocates into nucleus and promotes VP16-induced apoptosis (By similarity).By similarity

Sites

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Siteⁱ	137 – 138	Cleavage; by caspase-3By similarity		2
Siteⁱ	401 – 402	Cleavage; by caspase-3By similarity		2

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

EPDⁱ	O54781
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	O54781
PaxDbⁱ	O54781
PeptideAtlas More...PeptideAtlasⁱ	O54781
PRIDEⁱ	O54781

PTM databases

iPTMnetⁱ	O54781
PhosphoSitePlusⁱ	O54781

Expressionⁱ

Tissue specificityⁱ

Expressed in testes, lung and brain.1 Publication

Gene expression databases

CleanExⁱ	MM_SRPK2

CleanExⁱ

MM_SRPK2

Interactionⁱ

Subunit structureⁱ

Interacts with PKB/AKT1 in a phosphorylation-dependent manner. The phosphorylated form (by PKB/AKT1) interacts with YWHAB and YWHAE. Interaction with YWHAB suppresses its cleavage by caspases and inhibits the release of its N-terminal pro-apoptotic fragment. Interacts with SFN. Associates with U4/U6-U5 tri-small nuclear ribonucleoproteins (U4/U6-U5 tri-snRNPs) (By similarity). Interacts with ACIN1.By similarity1 Publication

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
SRSF1	Q07955	3	EBI-593325,EBI-398920	From Homo sapiens.

With

Entry

#Exp.

IntAct

Notes

SRSF1

Q07955

EBI-593325,EBI-398920

From Homo sapiens.

GO - Molecular functionⁱ

14-3-3 protein binding
Source: BHF-UCL
Inferred from direct assayⁱ
- 19592491

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	203503, 3 interactors
IntActⁱ	O54781, 4 interactors
STRINGⁱ	10090.ENSMUSP00000085734

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	O54781
SMRⁱ	O54781
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	79 – 681	Protein kinasePROSITE-ProRule annotationAdd BLAST		603

Sequence similaritiesⁱ

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family.Curated

Phylogenomic databases

eggNOGⁱ	KOG1290 Eukaryota ENOG410XRBH LUCA
HOGENOMⁱ	HOG000171558
HOVERGENⁱ	HBG108512
InParanoidⁱ	O54781
KEGG Orthology (KO) More...KOⁱ	K08831
PhylomeDBⁱ	O54781
TreeFamⁱ	TF105334

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009 Kinase-like_dom_sf IPR000719 Prot_kinase_dom IPR017441 Protein_kinase_ATP_BS IPR008271 Ser/Thr_kinase_AS
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00069 Pkinase, 2 hits
SMARTⁱ	View protein in SMART SM00220 S_TKc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS00107 PROTEIN_KINASE_ATP, 1 hit PS50011 PROTEIN_KINASE_DOM, 1 hit PS00108 PROTEIN_KINASE_ST, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

Sequence processingⁱ: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show all Align All

O54781-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSVNSEKSSS SERPEPQQKA PLVPPPPPPP PPPPLPDPAP PEPEEEILGS 
        60         70         80         90        100
DDEEQEDPAD YCKGGYHPVK IGDLFNGRYH VIRKLGWGHF STVWLCWDMQ 
       110        120        130        140        150
GKRFVAMKVV KSAQHYTETA LDEIKLLKCV RESDPSDPNK DMVVQLIDDF 
       160        170        180        190        200
KISGMNGIHV CMVFEVLGHH LLKWIIKSNY QGLPVRCVKS IIRQVLQGLD 
       210        220        230        240        250
YLHSKCKIIH TDIKPENILM CVDDAYVRRM AAEATEWQKA GAPPPSGSAV 
       260        270        280        290        300
STAPQQKPIG KISKNKKKKL KKKQKRQAEL LEKRLQEIEE LEREAERKIL 
       310        320        330        340        350
EENITSAEAS GEQDGEYQPE VTLKAADLED TTEEETAKDN GEVEDQEEKE 
       360        370        380        390        400
DAEKENAEKD EDDVEQELAN LDPTWVESPK ANGHIENGPF SLEQQLEDEE 
       410        420        430        440        450
DDEDDCANPE EYNLDEPNAE SDYTYSSSYE QFNGELPNGQ HKTSEFPTPL 
       460        470        480        490        500
FSGPLEPVAC GSVISEGSPL TEQEESSPSH DRSRTVSASS TGDLPKTKTR 
       510        520        530        540        550
AADLLVNPLD PRNADKIRVK IADLGNACWV HKHFTEDIQT RQYRSIEVLI 
       560        570        580        590        600
GAGYSTPADI WSTACMAFEL ATGDYLFEPH SGEDYSRDED HIAHIIELLG 
       610        620        630        640        650
SIPRHFALSG KYSREFFNRR GELRHITKLK PWSLFDVLVE KYGWPHEDAA 
       660        670        680 
QFTDFLIPML EMVPEKRASA GECLRHPWLN S

Length:681

Mass (Da):76,757

Last modified:July 5, 2005 - v2

Checksum:ⁱ1857EA955B2F9C0E

Computationally mapped potential isoform sequencesⁱ

There are 6 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

A0A0R4J124	A0A0R4J124_MOUSE	SRSF protein kinase 2 SRSF protein kinase 2 (Serine/arginine-rich protein specific kinase 2, isoform CRA_a)	Srpk2 mCG_4527	682	Annotation score:
Q6P5E1	Q6P5E1_MOUSE	SRSF protein kinase 2 SRSF protein kinase 2 (Srpk2 protein)	Srpk2	156	Annotation score:
A0A0G2JG74	A0A0G2JG74_MOUSE	SRSF protein kinase 2 SRSF protein kinase 2	Srpk2	134	Annotation score:
A0A0G2JDY2	A0A0G2JDY2_MOUSE	SRSF protein kinase 2 SRSF protein kinase 2	Srpk2	129	Annotation score:
A0A0G2JDT6	A0A0G2JDT6_MOUSE	SRSF protein kinase 2 SRSF protein kinase 2	Srpk2	57	Annotation score:
A0A0G2JEI1	A0A0G2JEI1_MOUSE	SRSF protein kinase 2 SRSF protein kinase 2	Srpk2	22	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	313	Q → QQ in AAH20178 (PubMed:15489334).Curated		1
Sequence conflictⁱ	368	L → P in BAA24055 (PubMed:9446799).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB006036 mRNA Translation: BAA24055.1 BC020178 mRNA Translation: AAH20178.1
PIRⁱ	JC5929
NCBI Reference Sequences More...RefSeqⁱ	NP_033300.2, NM_009274.2 XP_017176258.1, XM_017320769.1
UniGeneⁱ	Mm.288728

Genome annotation databases

GeneIDⁱ	20817
KEGGⁱ	mmu:20817
UCSC genome browser More...UCSCⁱ	uc008wqe.1 mouse

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
O54781	Uncharacterized protein		PIG		732	UniRef90_O54781
SRSF protein kinase 2 isoform X7		DELLE		723
SRSF protein kinase 2 isoform X4		Enhydra lutris kenyoni		723
Uncharacterized protein		FELCA		723
SRSF protein kinase 2		AILME		705
+128

Protein	Similar proteins		Species	Score	Length	Source
O54781	Uncharacterized protein		PIG		732	UniRef50_O54781
SRSF protein kinase 2 isoform X7		DELLE		723
Uncharacterized protein		FELCA		723
SRSF protein kinase 2 isoform X4		Enhydra lutris kenyoni		723
SRSF protein kinase 2		AILME		705
+554

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AB006036 mRNA Translation: BAA24055.1 BC020178 mRNA Translation: AAH20178.1
PIRⁱ	JC5929
RefSeqⁱ	NP_033300.2, NM_009274.2 XP_017176258.1, XM_017320769.1
UniGeneⁱ	Mm.288728

3D structure databases

ProteinModelPortalⁱ	O54781
SMRⁱ	O54781
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	203503, 3 interactors
IntActⁱ	O54781, 4 interactors
STRINGⁱ	10090.ENSMUSP00000085734

PTM databases

iPTMnetⁱ	O54781
PhosphoSitePlusⁱ	O54781

Proteomic databases

EPDⁱ	O54781
MaxQBⁱ	O54781
PaxDbⁱ	O54781
PeptideAtlasⁱ	O54781
PRIDEⁱ	O54781

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

GeneIDⁱ	20817
KEGGⁱ	mmu:20817
UCSCⁱ	uc008wqe.1 mouse

Organism-specific databases

CTDⁱ	6733
MGIⁱ	MGI:1201408 Srpk2

Phylogenomic databases

eggNOGⁱ	KOG1290 Eukaryota ENOG410XRBH LUCA
HOGENOMⁱ	HOG000171558
HOVERGENⁱ	HBG108512
InParanoidⁱ	O54781
KOⁱ	K08831
PhylomeDBⁱ	O54781
TreeFamⁱ	TF105334

Miscellaneous databases

ChiTaRSⁱ	Srpk2 mouse
Protein Ontology More...PROⁱ	PR:O54781
SOURCEⁱ	Search...

Gene expression databases

CleanExⁱ	MM_SRPK2

CleanExⁱ

MM_SRPK2

Family and domain databases

InterProⁱ	View protein in InterPro IPR011009 Kinase-like_dom_sf IPR000719 Prot_kinase_dom IPR017441 Protein_kinase_ATP_BS IPR008271 Ser/Thr_kinase_AS
Pfamⁱ	View protein in Pfam PF00069 Pkinase, 2 hits
SMARTⁱ	View protein in SMART SM00220 S_TKc, 1 hit
SUPFAMⁱ	SSF56112 SSF56112, 1 hit
PROSITEⁱ	View protein in PROSITE PS00107 PROTEIN_KINASE_ATP, 1 hit PS50011 PROTEIN_KINASE_DOM, 1 hit PS00108 PROTEIN_KINASE_ST, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	SRPK2_MOUSE
Accessionⁱ	O54781Primary (citable) accession number: O54781 Secondary accession number(s): Q8VCD9
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	July 5, 2005
	Last sequence update:	July 5, 2005
	Last modified:	November 7, 2018
	This is version 139 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
Human and mouse protein kinases
Human and mouse protein kinases: classification and index

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - O54781 (SRPK2_MOUSE)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

SRSF protein kinase 2

Srpk2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Other locations

Cytosol

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Sites

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ