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Entry version 145 (02 Dec 2020)
Sequence version 1 (01 Jun 1998)
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Protein

Sodium/potassium/calcium exchanger 2

Gene

Slc24a2

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Critical component of the visual transduction cascade, controlling the calcium concentration of outer segments during light and darkness. Light causes a rapid lowering of cytosolic free calcium in the outer segment of both retinal rod and cone photoreceptors and the light-induced lowering of calcium is caused by extrusion via this protein which plays a key role in the process of light adaptation. Transports 1 Ca2+ and 1 K+ in exchange for 4 Na+.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processAntiport, Calcium transport, Ion transport, Potassium transport, Sensory transduction, Sodium transport, Symport, Transport, Vision
LigandCalcium, Potassium, Sodium

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-RNO-425561, Sodium/Calcium exchangers

Protein family/group databases

Transport Classification Database

More...
TCDBi
2.A.19.4.2, the ca(2+):cation antiporter (caca) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Sodium/potassium/calcium exchanger 2
Alternative name(s):
Na(+)/K(+)/Ca(2+)-exchange protein 2
Retinal cone Na-Ca+K exchanger
Solute carrier family 24 member 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Slc24a2
Synonyms:Nckx2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiRattus norvegicus (Rat)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10116 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000002494 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 5

Organism-specific databases

Rat genome database

More...
RGDi
628650, Slc24a2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 38CytoplasmicSequence analysisAdd BLAST38
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei39 – 59HelicalSequence analysisAdd BLAST21
Topological domaini60 – 133ExtracellularSequence analysisAdd BLAST74
Transmembranei134 – 154HelicalSequence analysisAdd BLAST21
Topological domaini155 – 179CytoplasmicSequence analysisAdd BLAST25
Transmembranei180 – 200HelicalSequence analysisAdd BLAST21
Topological domaini201 – 205ExtracellularSequence analysis5
Transmembranei206 – 226HelicalSequence analysisAdd BLAST21
Topological domaini227 – 244CytoplasmicSequence analysisAdd BLAST18
Transmembranei245 – 265HelicalSequence analysisAdd BLAST21
Topological domaini266ExtracellularSequence analysis1
Transmembranei267 – 287HelicalSequence analysisAdd BLAST21
Topological domaini288 – 506CytoplasmicSequence analysisAdd BLAST219
Transmembranei507 – 527HelicalSequence analysisAdd BLAST21
Topological domaini528 – 542ExtracellularSequence analysisAdd BLAST15
Transmembranei543 – 563HelicalSequence analysisAdd BLAST21
Topological domaini564 – 578CytoplasmicSequence analysisAdd BLAST15
Transmembranei579 – 599HelicalSequence analysisAdd BLAST21
Topological domaini600 – 611ExtracellularSequence analysisAdd BLAST12
Transmembranei612 – 632HelicalSequence analysisAdd BLAST21
Topological domaini633 – 639CytoplasmicSequence analysis7
Transmembranei640 – 660HelicalSequence analysisAdd BLAST21
Topological domaini661 – 670ExtracellularSequence analysis10

Keywords - Cellular componenti

Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000193681 – 670Sodium/potassium/calcium exchanger 2Add BLAST670

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi112N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei337PhosphoserineCombined sources1
Modified residuei341PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
O54701

PRoteomics IDEntifications database

More...
PRIDEi
O54701

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
O54701, 1 site

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
O54701

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
O54701

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed abundantly in all regions of the brain and weakly in the eye, large intestine and adrenal tissue.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSRNOG00000008169, Expressed in Ammon's horn and 13 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
O54701, RN

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
250001, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10116.ENSRNOP00000010827

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati175 – 215Alpha-1Add BLAST41
Repeati550 – 581Alpha-2Add BLAST32

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1307, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00990000203658

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_007948_5_1_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
O54701

Identification of Orthologs from Complete Genome Data

More...
OMAi
WPLFRDM

Database of Orthologous Groups

More...
OrthoDBi
1168500at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
O54701

TreeFam database of animal gene trees

More...
TreeFami
TF318759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR004481, K/Na/Ca-exchanger
IPR004837, NaCa_Exmemb
IPR030236, SLC24A2

The PANTHER Classification System

More...
PANTHERi
PTHR10846, PTHR10846, 1 hit
PTHR10846:SF41, PTHR10846:SF41, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01699, Na_Ca_ex, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00367, TIGR00367, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: O54701-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MDLHQSATVR LLQEWCSHES PSGCRRHYNT RKKLKLIRVI GLVMGLVAVS
60 70 80 90 100
TVPFSISAFT ETYSQNNRGE ASDVTGPRAA PGHRQRTLLD LNDKIRDYTP
110 120 130 140 150
QPPASQEDRS ENGTDHAQGD YPKDVFSLEE RRKGAIILHV IGMIYMFIAL
160 170 180 190 200
AIVCDEFFVP SLTVITEKLG ISDDVAGATF MAAGGSAPEL FTSLIGVFIA
210 220 230 240 250
HSNVGIGTIV GSAVFNILFV IGMCALFSRE ILNLTWWPLF RDVSFYIVDL
260 270 280 290 300
IMLIIFFLDN VIMWWESLLL LTAYFAYVVF MKFNVQVERW VKQMINRNKV
310 320 330 340 350
VKVTVSEAQA KASTAGDKEE PTLPNKPRLQ RGGSSASLHN SLMRNSIFQL
360 370 380 390 400
MIHTLDPLAE ELGSYGKLKY YDTMTEEGRF REKASILHKI AKKKCQVDEN
410 420 430 440 450
ERQNGAANHV DYAAEKIELP NSTSTEVEMT PSSEASEPVQ NGNLSHSIEA
460 470 480 490 500
ADAPQATETA EEDDDQPLSL SWPSNTRKQI TFLIVLPIVF PLWITLPDVR
510 520 530 540 550
KPASKKFFPI TFFGSITWIA VFSYLMVWWA HQVGETIGIS EEIMGLTILA
560 570 580 590 600
AGTSIPDLIT SVIVARKGLG DMAVSSSVGS NIFDITVGLP LPWLLYTIIH
610 620 630 640 650
RFKPVTVSSN GLFCAIVLLF IMLIFVILSI ALCKWRMNKI LGFIMFGLYF
660 670
AFLVVSVLLE DKVLECPVSI
Length:670
Mass (Da):74,657
Last modified:June 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i4E855A467FC6679E
GO
Isoform 2 (identifier: O54701-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     360-376: Missing.

Show »
Length:653
Mass (Da):72,647
Checksum:i510AD46CF3884AF5
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti309Q → R in AAC19404 (PubMed:9461611).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_006165360 – 376Missing in isoform 2. 1 PublicationAdd BLAST17

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF021923 mRNA Translation: AAC19405.1
AF027506 mRNA Translation: AAC19404.1

NCBI Reference Sequences

More...
RefSeqi
NP_113931.1, NM_031743.2 [O54701-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSRNOT00000010827; ENSRNOP00000010827; ENSRNOG00000008169 [O54701-1]
ENSRNOT00000083373; ENSRNOP00000074180; ENSRNOG00000008169 [O54701-1]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
84550

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
rno:84550

UCSC genome browser

More...
UCSCi
RGD:628650, rat [O54701-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF021923 mRNA Translation: AAC19405.1
AF027506 mRNA Translation: AAC19404.1
RefSeqiNP_113931.1, NM_031743.2 [O54701-1]

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi250001, 1 interactor
STRINGi10116.ENSRNOP00000010827

Protein family/group databases

TCDBi2.A.19.4.2, the ca(2+):cation antiporter (caca) family

PTM databases

GlyGeniO54701, 1 site
iPTMnetiO54701
PhosphoSitePlusiO54701

Proteomic databases

PaxDbiO54701
PRIDEiO54701

Genome annotation databases

EnsembliENSRNOT00000010827; ENSRNOP00000010827; ENSRNOG00000008169 [O54701-1]
ENSRNOT00000083373; ENSRNOP00000074180; ENSRNOG00000008169 [O54701-1]
GeneIDi84550
KEGGirno:84550
UCSCiRGD:628650, rat [O54701-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
25769
RGDi628650, Slc24a2

Phylogenomic databases

eggNOGiKOG1307, Eukaryota
GeneTreeiENSGT00990000203658
HOGENOMiCLU_007948_5_1_1
InParanoidiO54701
OMAiWPLFRDM
OrthoDBi1168500at2759
PhylomeDBiO54701
TreeFamiTF318759

Enzyme and pathway databases

ReactomeiR-RNO-425561, Sodium/Calcium exchangers

Miscellaneous databases

Protein Ontology

More...
PROi
PR:O54701

Gene expression databases

BgeeiENSRNOG00000008169, Expressed in Ammon's horn and 13 other tissues
GenevisibleiO54701, RN

Family and domain databases

InterProiView protein in InterPro
IPR004481, K/Na/Ca-exchanger
IPR004837, NaCa_Exmemb
IPR030236, SLC24A2
PANTHERiPTHR10846, PTHR10846, 1 hit
PTHR10846:SF41, PTHR10846:SF41, 1 hit
PfamiView protein in Pfam
PF01699, Na_Ca_ex, 2 hits
TIGRFAMsiTIGR00367, TIGR00367, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNCKX2_RAT
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O54701
Secondary accession number(s): O54706
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 13, 2001
Last sequence update: June 1, 1998
Last modified: December 2, 2020
This is version 145 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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