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Entry version 98 (07 Apr 2021)
Sequence version 1 (01 Jun 1998)
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Protein
Submitted name:

EscU

Gene

escU

Organism
Escherichia coli
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

Protein family/group databases

MEROPS protease database

More...
MEROPSi
N06.003

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
EscUImported
Submitted name:
EscU proteinImported
Submitted name:
EscU/YscU/HrcU family type III secretion system export apparatus switch proteinImported
Submitted name:
T3SS structure protein EscUImported
Submitted name:
Type III secretion system LEE export apparatus switch protein EscUImported
Submitted name:
Type III secretion system, LEE associatedImported
Submitted name:
Yop proteins translocation protein UImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:escUImported
Synonyms:yscUImported
ORF Names:BON63_23750Imported, D9E49_10510Imported, DL800_21895Imported, E2855_03880Imported, E2863_03727Imported, EC95NR1_02313Imported, ERS085406_02322Imported, ERS150873_02495Imported, HVV39_11325Imported, HVW44_21590Imported, HVX60_20200Imported, L537_056Imported, LDEC_048Imported, LIHIT_052Imported, NCTC10089_00074Imported, NCTC8621_00110Imported, NCTC8959_03693Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiEscherichia coliImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri562 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacteralesEnterobacteriaceaeEscherichia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000406392 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence
  • UP000514533 Componenti: Chromosome
  • UP000514498 Componenti: Chromosome
  • UP000272738 Componenti: Chromosome
  • UP000298241 Componenti: Unassembled WGS sequence
  • UP000281900 Componenti: Chromosome
  • UP000250208 Componenti: Chromosome
  • UP000255118 Componenti: Unassembled WGS sequence
  • UP000247985 Componenti: Chromosome
  • UP000255093 Componenti: Unassembled WGS sequence
  • UP000042305 Componenti: Unassembled WGS sequence
  • UP000271175 Componenti: Unassembled WGS sequence
  • UP000514528 Componenti: Chromosome
  • UP000043018 Componenti: Unassembled WGS sequence

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei35 – 55HelicalSequence analysisAdd BLAST21
Transmembranei143 – 161HelicalSequence analysisAdd BLAST19
Transmembranei173 – 204HelicalSequence analysisAdd BLAST32

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the type III secretion exporter family.ARBA annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1690.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006307, BsaZ
IPR006135, T3SS_substrate_exporter
IPR029025, T3SS_substrate_exporter_C

The PANTHER Classification System

More...
PANTHERi
PTHR30531, PTHR30531, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01312, Bac_export_2, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00950, TYPE3IMSPROT

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF160544, SSF160544, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01404, FlhB_rel_III, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

O52130-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEKTEKPTP KKLRDLKKKG DVTKSEEVMA AVQSLILFSF FSLYGMSFFV
60 70 80 90 100
DIVGLVNTTI DSLNRPFLYA IREILGAVLN IFLLYILPIS LIVFVGTVTT
110 120 130 140 150
GVSQIGFIFA VEKIKPSAQK ISVKNNLKNI FSVKSIFELL KSVFKLVIIV
160 170 180 190 200
LIFYFMGHSY ANEFANFTGL NAYQALVVVA FFVFLLWKGV LFGYLLFSVF
210 220 230 240 250
DFWFQKHEGL KKMKMSKDEV KREAKDTDGN PEIKGERRRL HSEIQSGSLA
260 270 280 290 300
NNIKKSTVIV KNPTHIAICL YYKLGETPLP LVIETGKDAK ALQIIKLAEL
310 320 330 340
YDIPVIEDIP LARSLYKNIH KGQYITEDFF EPVAQLIRIA IDLDY
Length:345
Mass (Da):39,177
Last modified:June 1, 1998 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF2F3941BDA27D845
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF022236 Genomic DNA Translation: AAC38372.1
CP021339 Genomic DNA Translation: ART26083.1
CP029692 Genomic DNA Translation: AWS38220.1
AP018796 Genomic DNA Translation: BBF49438.1
AP018802 Genomic DNA Translation: BBF55182.1
AJ633129 Genomic DNA Translation: CAG17518.1
FM986650 Genomic DNA Translation: CAX18590.1
FM986651 Genomic DNA Translation: CAX18665.1
FM986652 Genomic DNA Translation: CAX18745.1
CYBW01000011 Genomic DNA Translation: CTU59700.1
CYFX01000014 Genomic DNA Translation: CTZ47860.1
ROAL01000008 Genomic DNA Translation: MIB60829.1
CP055951 Genomic DNA Translation: QMS02042.1
CP055967 Genomic DNA Translation: QMS21185.1
CP055981 Genomic DNA Translation: QMS38585.1
UFZD01000005 Genomic DNA Translation: STE12927.1
UGBW01000003 Genomic DNA Translation: STH80244.1
MTWW01000095 Genomic DNA Translation: TEY97262.1
CABEEY010000003 Genomic DNA Translation: VTR11300.1

NCBI Reference Sequences

More...
RefSeqi
WP_001291693.1, NZ_WSWY01000130.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
ART26083; ART26083; EC95NR1_02313
AWS38220; AWS38220; DL800_21895
BBF49438; BBF49438; E2855_03880
BBF55182; BBF55182; E2863_03727
CTU59700; CTU59700; ERS085406_02322
CTZ47860; CTZ47860; ERS150873_02495
STE12927; STE12927; NCTC8959_03693
STH80244; STH80244; NCTC8621_00110

Pathosystems Resource Integration Center (PATRIC)

More...
PATRICi
fig|562.7234.peg.3361

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF022236 Genomic DNA Translation: AAC38372.1
CP021339 Genomic DNA Translation: ART26083.1
CP029692 Genomic DNA Translation: AWS38220.1
AP018796 Genomic DNA Translation: BBF49438.1
AP018802 Genomic DNA Translation: BBF55182.1
AJ633129 Genomic DNA Translation: CAG17518.1
FM986650 Genomic DNA Translation: CAX18590.1
FM986651 Genomic DNA Translation: CAX18665.1
FM986652 Genomic DNA Translation: CAX18745.1
CYBW01000011 Genomic DNA Translation: CTU59700.1
CYFX01000014 Genomic DNA Translation: CTZ47860.1
ROAL01000008 Genomic DNA Translation: MIB60829.1
CP055951 Genomic DNA Translation: QMS02042.1
CP055967 Genomic DNA Translation: QMS21185.1
CP055981 Genomic DNA Translation: QMS38585.1
UFZD01000005 Genomic DNA Translation: STE12927.1
UGBW01000003 Genomic DNA Translation: STH80244.1
MTWW01000095 Genomic DNA Translation: TEY97262.1
CABEEY010000003 Genomic DNA Translation: VTR11300.1
RefSeqiWP_001291693.1, NZ_WSWY01000130.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

MEROPSiN06.003

Genome annotation databases

EnsemblBacteriaiART26083; ART26083; EC95NR1_02313
AWS38220; AWS38220; DL800_21895
BBF49438; BBF49438; E2855_03880
BBF55182; BBF55182; E2863_03727
CTU59700; CTU59700; ERS085406_02322
CTZ47860; CTZ47860; ERS150873_02495
STE12927; STE12927; NCTC8959_03693
STH80244; STH80244; NCTC8621_00110
PATRICifig|562.7234.peg.3361

Family and domain databases

Gene3Di3.40.1690.10, 1 hit
InterProiView protein in InterPro
IPR006307, BsaZ
IPR006135, T3SS_substrate_exporter
IPR029025, T3SS_substrate_exporter_C
PANTHERiPTHR30531, PTHR30531, 1 hit
PfamiView protein in Pfam
PF01312, Bac_export_2, 1 hit
PRINTSiPR00950, TYPE3IMSPROT
SUPFAMiSSF160544, SSF160544, 1 hit
TIGRFAMsiTIGR01404, FlhB_rel_III, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiO52130_ECOLX
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: O52130
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 1998
Last sequence update: June 1, 1998
Last modified: April 7, 2021
This is version 98 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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