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Protein

Putative arsenical resistance operon repressor ArsR

Gene

arsR

Organism
Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Transcriptional repressor for the arsADRC operon.By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
DNA bindingi73 – 96H-T-H motifPROSITE-ProRule annotationAdd BLAST24

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding, Repressor
Biological processArsenical resistance, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Putative arsenical resistance operon repressor ArsR
Gene namesi
Name:arsR
Ordered Locus Names:VNG_5182G
Encoded oniPlasmid pNRC1000 Publication
OrganismiHalobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Taxonomic identifieri64091 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaStenosarchaea groupHalobacteriaHalobacterialesHalobacteriaceaeHalobacterium
Proteomesi
  • UP000000554 Componenti: Plasmid pNRC100

Pathology & Biotechi

Disruption phenotypei

Deletion of the arsADRC operon results in increased sensitivity to arsenite and antimonite but not arsenate.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004291141 – 129Putative arsenical resistance operon repressor ArsRAdd BLAST129

Expressioni

Inductioni

By arsenite and antimonite.1 Publication

Structurei

3D structure databases

ProteinModelPortaliO52029
SMRiO52029
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini37 – 129HTH arsR-typePROSITE-ProRule annotationAdd BLAST93

Phylogenomic databases

InParanoidiO52029
OMAiVCEFAPL
OrthoDBiPOG093Z09YN
PhylomeDBiO52029

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR001845 HTH_ArsR_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01022 HTH_5, 1 hit
PRINTSiPR00778 HTHARSR
SMARTiView protein in SMART
SM00418 HTH_ARSR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50987 HTH_ARSR_2, 1 hit

Sequencei

Sequence statusi: Complete.

O52029-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSSTERLQRY LTDERGGCGD EEVAQRLDEL EELDAAAGGP ALEADVGVLS
60 70 80 90 100
ALANETRYKI IRILHIAGEE LCVCEFSPLL DVSDSAISHS LSQLTEAGLV
110 120
TRRKDGKWRK YQTTMRGDAL LVALNGSRR
Length:129
Mass (Da):14,150
Last modified:June 1, 1998 - v1
Checksum:iD64406438B042E2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF016485 Genomic DNA Translation: AAC82909.1
PIRiT08342

Genome annotation databases

EnsemblBacteriaiAAC82909; AAC82909; AAC82909
KEGGihal:arsR

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF016485 Genomic DNA Translation: AAC82909.1
PIRiT08342

3D structure databases

ProteinModelPortaliO52029
SMRiO52029
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC82909; AAC82909; AAC82909
KEGGihal:arsR

Phylogenomic databases

InParanoidiO52029
OMAiVCEFAPL
OrthoDBiPOG093Z09YN
PhylomeDBiO52029

Family and domain databases

CDDicd00090 HTH_ARSR, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR011991 ArsR-like_HTH
IPR001845 HTH_ArsR_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PfamiView protein in Pfam
PF01022 HTH_5, 1 hit
PRINTSiPR00778 HTHARSR
SMARTiView protein in SMART
SM00418 HTH_ARSR, 1 hit
SUPFAMiSSF46785 SSF46785, 1 hit
PROSITEiView protein in PROSITE
PS50987 HTH_ARSR_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiARSR_HALSA
AccessioniPrimary (citable) accession number: O52029
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 14, 2014
Last sequence update: June 1, 1998
Last modified: November 7, 2018
This is version 106 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Plasmid, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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